{"id":"https://openalex.org/W4396833751","doi":"https://doi.org/10.1007/s00284-024-03671-3","title":"An Overview of SARS-CoV-2 Potential Targets, Inhibitors, and Computational Insights to Enrich the Promising Treatment Strategies","display_name":"An Overview of SARS-CoV-2 Potential Targets, Inhibitors, and Computational Insights to Enrich the Promising Treatment Strategies","publication_year":2024,"publication_date":"2024-05-11","ids":{"openalex":"https://openalex.org/W4396833751","doi":"https://doi.org/10.1007/s00284-024-03671-3","pmid":"https://pubmed.ncbi.nlm.nih.gov/38733424"},"language":"en","primary_location":{"id":"doi:10.1007/s00284-024-03671-3","doi":"https://doi.org/10.1007/s00284-024-03671-3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00284-024-03671-3","pdf_url":null,"source":{"id":"https://openalex.org/S2248630","display_name":"Current Microbiology","issn_l":"0343-8651","issn":["0343-8651","1432-0991"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Microbiology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W4396833751"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5094312059","display_name":"Pooja Kumawat","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I43218427","display_name":"Mohanlal Sukhadia University","ror":"https://ror.org/00z10e966","country_code":"IN","type":"education","lineage":["https://openalex.org/I43218427"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pooja Kumawat","raw_affiliation_strings":["Department of Chemistry, Mohanlal Sukhadia University, Udaipur, Rajasthan, 313001, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Mohanlal Sukhadia University, Udaipur, Rajasthan, 313001, India","institution_ids":["https://openalex.org/I43218427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086481629","display_name":"Lokesh Kumar Agarwal","orcid":"https://orcid.org/0000-0002-2731-3328","observed_orcids":["https://orcid.org/0000-0002-2731-3328"]},"institutions":[{"id":"https://openalex.org/I43218427","display_name":"Mohanlal Sukhadia University","ror":"https://ror.org/00z10e966","country_code":"IN","type":"education","lineage":["https://openalex.org/I43218427"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Lokesh Kumar Agarwal","raw_affiliation_strings":["Department of Chemistry, Mohanlal Sukhadia University, Udaipur, Rajasthan, 313001, India. lokeshmittal24@gmail.com"],"raw_orcid":"https://orcid.org/0000-0002-2731-3328","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Mohanlal Sukhadia University, Udaipur, Rajasthan, 313001, India. lokeshmittal24@gmail.com","institution_ids":["https://openalex.org/I43218427"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021391766","display_name":"Kuldeep Raj Sharma","orcid":"https://orcid.org/0000-0002-1103-034X","observed_orcids":["https://orcid.org/0000-0002-1103-034X"]},"institutions":[{"id":"https://openalex.org/I43218427","display_name":"Mohanlal Sukhadia University","ror":"https://ror.org/00z10e966","country_code":"IN","type":"education","lineage":["https://openalex.org/I43218427"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Kuldeep Sharma","raw_affiliation_strings":["Department of Botany, Mohanlal Sukhadia University, Udaipur, Rajasthan, 313001, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Botany, Mohanlal Sukhadia University, Udaipur, Rajasthan, 313001, India","institution_ids":["https://openalex.org/I43218427"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5086481629"],"corresponding_institution_ids":["https://openalex.org/I43218427"],"apc_list":{"value":3690,"currency":"USD","value_usd":3690},"apc_paid":null,"fwci":0.5644,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.50539114,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"81","issue":"7","first_page":"169","last_page":"169"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.7476000189781189,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.7476000189781189,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.24449999630451202,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sars-cov-2","display_name":"SARS-CoV-2","score":1.0},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.8889999985694885},{"id":"https://openalex.org/keywords/antiviral-drug-targets","display_name":"antiviral drug targets","score":0.8169999718666077},{"id":"https://openalex.org/keywords/drug-repurposing","display_name":"drug repurposing","score":0.843999981880188},{"id":"https://openalex.org/keywords/fda-approved-drugs","display_name":"FDA-approved drugs","score":0.8949999809265137},{"id":"https://openalex.org/keywords/viral-entry-receptor","display_name":"viral entry receptor","score":0.6890000104904175},{"id":"https://openalex.org/keywords/viral-rna-replication","display_name":"viral RNA replication","score":0.5540000200271606},{"id":"https://openalex.org/keywords/host-cell-factors","display_name":"host cell factors","score":0.5759999752044678},{"id":"https://openalex.org/keywords/molecular-docking","display_name":"molecular docking","score":0.7450000047683716},{"id":"https://openalex.org/keywords/molecular-dynamics","display_name":"molecular dynamics","score":0.828000009059906},{"id":"https://openalex.org/keywords/qsar-modeling","display_name":"QSAR models","score":0.8740000128746033},{"id":"https://openalex.org/keywords/homology-modeling","display_name":"homology modeling","score":0.9990000128746033},{"id":"https://openalex.org/keywords/network-pharmacology","display_name":"network pharmacology","score":0.8889999985694885},{"id":"https://openalex.org/keywords/therapeutic-compounds","display_name":"therapeutic compounds","score":0.5210000276565552}],"concepts":[{"id":"https://openalex.org/C10679952","wikidata":"https://www.wikidata.org/wiki/Q5308937","display_name":"Druggability","level":3,"score":0.8595708608627319},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6911383271217346},{"id":"https://openalex.org/C519536355","wikidata":"https://www.wikidata.org/wiki/Q21021151","display_name":"Repurposing","level":2,"score":0.6829149723052979},{"id":"https://openalex.org/C103637391","wikidata":"https://www.wikidata.org/wiki/Q5308921","display_name":"Drug repositioning","level":3,"score":0.6652054190635681},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.6186031103134155},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.5515876412391663},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.5346009135246277},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.5056204795837402},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49094775319099426},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.45188793540000916},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.32368171215057373},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3135897219181061},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.20835286378860474},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.17854049801826477},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17670002579689026},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09763169288635254},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.08814248442649841},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D000093485","descriptor_name":"COVID-19 Drug Treatment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053586","descriptor_name":"Virus Internalization","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062105","descriptor_name":"Molecular Docking Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00284-024-03671-3","doi":"https://doi.org/10.1007/s00284-024-03671-3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00284-024-03671-3","pdf_url":null,"source":{"id":"https://openalex.org/S2248630","display_name":"Current Microbiology","issn_l":"0343-8651","issn":["0343-8651","1432-0991"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Microbiology","raw_type":"journal-article"},{"id":"pmid:38733424","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38733424","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current microbiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":151,"referenced_works":["https://openalex.org/W1981635318","https://openalex.org/W1994542643","https://openalex.org/W2023026872","https://openalex.org/W2055818289","https://openalex.org/W2060197609","https://openalex.org/W2063052710","https://openalex.org/W2067933199","https://openalex.org/W2093762900","https://openalex.org/W2095928865","https://openalex.org/W2140674451","https://openalex.org/W2156095183","https://openalex.org/W2566478608","https://openalex.org/W2791400386","https://openalex.org/W2889848040","https://openalex.org/W2946011020","https://openalex.org/W2948728900","https://openalex.org/W2979704953","https://openalex.org/W2998849726","https://openalex.org/W3008357263","https://openalex.org/W3008874180","https://openalex.org/W3009487812","https://openalex.org/W3009912996","https://openalex.org/W3010096538","https://openalex.org/W3010761615","https://openalex.org/W3011994656","https://openalex.org/W3013017333","https://openalex.org/W3013351884","https://openalex.org/W3014067025","https://openalex.org/W3014108899","https://openalex.org/W3014912119","https://openalex.org/W3014941429","https://openalex.org/W3015608194","https://openalex.org/W3017185871","https://openalex.org/W3017897776","https://openalex.org/W3019773443","https://openalex.org/W3019884735","https://openalex.org/W3020188044","https://openalex.org/W3021431776","https://openalex.org/W3023221016","https://openalex.org/W3023489051","https://openalex.org/W3023813595","https://openalex.org/W3023915741","https://openalex.org/W3025259434","https://openalex.org/W3025681749","https://openalex.org/W3027002382","https://openalex.org/W3028333352","https://openalex.org/W3030158388","https://openalex.org/W3030672595","https://openalex.org/W3033425553","https://openalex.org/W3033737840","https://openalex.org/W3034928480","https://openalex.org/W3035194289","https://openalex.org/W3036854260","https://openalex.org/W3038925213","https://openalex.org/W3039031817","https://openalex.org/W3039628420","https://openalex.org/W3042238480","https://openalex.org/W3043959829","https://openalex.org/W3044577259","https://openalex.org/W3045079087","https://openalex.org/W3048018942","https://openalex.org/W3049368833","https://openalex.org/W3080870377","https://openalex.org/W3084101718","https://openalex.org/W3086125063","https://openalex.org/W3087412931","https://openalex.org/W3087462052","https://openalex.org/W3087968175","https://openalex.org/W3089094108","https://openalex.org/W3091482221","https://openalex.org/W3092564100","https://openalex.org/W3093227781","https://openalex.org/W3093244828","https://openalex.org/W3093802804","https://openalex.org/W3094827588","https://openalex.org/W3096612840","https://openalex.org/W3096967708","https://openalex.org/W3102920585","https://openalex.org/W3103134232","https://openalex.org/W3107594385","https://openalex.org/W3108730183","https://openalex.org/W3108943871","https://openalex.org/W3111902275","https://openalex.org/W3112213940","https://openalex.org/W3112434525","https://openalex.org/W3115307704","https://openalex.org/W3118438588","https://openalex.org/W3119410748","https://openalex.org/W3120330984","https://openalex.org/W3121303844","https://openalex.org/W3123629693","https://openalex.org/W3124383924","https://openalex.org/W3125823132","https://openalex.org/W3129250372","https://openalex.org/W3130866895","https://openalex.org/W3132448805","https://openalex.org/W3133131390","https://openalex.org/W3139690347","https://openalex.org/W3143964243","https://openalex.org/W3147842526","https://openalex.org/W3151285714","https://openalex.org/W3152451364","https://openalex.org/W3156297617","https://openalex.org/W3159140204","https://openalex.org/W3165101199","https://openalex.org/W3167671574","https://openalex.org/W3168338972","https://openalex.org/W3172207918","https://openalex.org/W3172729509","https://openalex.org/W3173109789","https://openalex.org/W3173207811","https://openalex.org/W3173617135","https://openalex.org/W3174010563","https://openalex.org/W3175376340","https://openalex.org/W3175692790","https://openalex.org/W3176005660","https://openalex.org/W3176010026","https://openalex.org/W3176158657","https://openalex.org/W3189312452","https://openalex.org/W3199073859","https://openalex.org/W3200289956","https://openalex.org/W3203433659","https://openalex.org/W3206652304","https://openalex.org/W3212423563","https://openalex.org/W4206594482","https://openalex.org/W4210314238","https://openalex.org/W4210623453","https://openalex.org/W4211179425","https://openalex.org/W4212836998","https://openalex.org/W4212960604","https://openalex.org/W4213075232","https://openalex.org/W4220911787","https://openalex.org/W4221012348","https://openalex.org/W4225397093","https://openalex.org/W4226023710","https://openalex.org/W4283071258","https://openalex.org/W4285011397","https://openalex.org/W4295095393","https://openalex.org/W4295877110","https://openalex.org/W4297517595","https://openalex.org/W4313259721","https://openalex.org/W4321478649","https://openalex.org/W4361217414","https://openalex.org/W4362636640","https://openalex.org/W4367049415","https://openalex.org/W4367185566","https://openalex.org/W4381058445","https://openalex.org/W4382918674","https://openalex.org/W4384627093","https://openalex.org/W4385798459","https://openalex.org/W4391486089"],"related_works":["https://openalex.org/W4301394357","https://openalex.org/W4399894916","https://openalex.org/W3114112383","https://openalex.org/W3132154046","https://openalex.org/W3016499017","https://openalex.org/W3156958256","https://openalex.org/W3145330140","https://openalex.org/W4211098593","https://openalex.org/W4411858196","https://openalex.org/W4394783303"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":7}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2024-05-12T00:00:00"}