{"id":"https://openalex.org/W4396818014","doi":"https://doi.org/10.1107/s2053273323087521","title":"Steps forward beyond the crystal structures: MAXS reveals the potential massive movements during the catalytic action of a kinase","display_name":"Steps forward beyond the crystal structures: MAXS reveals the potential massive movements during the catalytic action of a kinase","publication_year":2023,"publication_date":"2023-08-22","ids":{"openalex":"https://openalex.org/W4396818014","doi":"https://doi.org/10.1107/s2053273323087521"},"language":"en","primary_location":{"id":"doi:10.1107/s2053273323087521","doi":"https://doi.org/10.1107/s2053273323087521","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1107/s2053273323087521","pdf_url":null,"source":{"id":"https://openalex.org/S4393918093","display_name":"Acta Crystallographica Section A Foundations and Advances","issn_l":"2053-2733","issn":["2053-2733"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","norway-1","poland-200","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Crystallographica Section A Foundations and Advances","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002201813","display_name":"Takashi Matsumoto","orcid":"https://orcid.org/0000-0003-0639-9262","observed_orcids":["https://orcid.org/0000-0003-0639-9262"]},"institutions":[{"id":"https://openalex.org/I4210114347","display_name":"Rigaku (Japan)","ror":"https://ror.org/01z4jpw82","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210114347"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T. Matsumoto","raw_affiliation_strings":["Rigaku Corporation, 3-9-12 Matsubara-cho, Akishima, Tokyo 196-8666, Japan,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rigaku Corporation, 3-9-12 Matsubara-cho, Akishima, Tokyo 196-8666, Japan,","institution_ids":["https://openalex.org/I4210114347"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062160341","display_name":"Akihito Yamano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114347","display_name":"Rigaku (Japan)","ror":"https://ror.org/01z4jpw82","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210114347"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"A. Yamano","raw_affiliation_strings":["Rigaku Corporation, 3-9-12 Matsubara-cho, Akishima, Tokyo 196-8666, Japan,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rigaku Corporation, 3-9-12 Matsubara-cho, Akishima, Tokyo 196-8666, Japan,","institution_ids":["https://openalex.org/I4210114347"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054921161","display_name":"Yuka Murakawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387152983","display_name":"Osaka Metropolitan University","ror":"https://ror.org/01hvx5h04","country_code":"JP","type":"education","lineage":["https://openalex.org/I4387152983"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y. Murakawa","raw_affiliation_strings":["Graduate School of Science, Osaka Metropolitan University, 1-1 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8531, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Science, Osaka Metropolitan University, 1-1 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8531, Japan","institution_ids":["https://openalex.org/I4387152983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113526275","display_name":"H. Fukada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387152983","display_name":"Osaka Metropolitan University","ror":"https://ror.org/01hvx5h04","country_code":"JP","type":"education","lineage":["https://openalex.org/I4387152983"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"H. Fukada","raw_affiliation_strings":["Graduate School of Science, Osaka Metropolitan University, 1-1 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8531, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Science, Osaka Metropolitan University, 1-1 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8531, Japan","institution_ids":["https://openalex.org/I4387152983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011509062","display_name":"Masaaki Sawa","orcid":"https://orcid.org/0000-0002-0077-2188","observed_orcids":["https://orcid.org/0000-0002-0077-2188"]},"institutions":[{"id":"https://openalex.org/I4405285453","display_name":"Carna Biosciences (Japan)","ror":"https://ror.org/05fw9gc86","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405285453"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"M. Sawa","raw_affiliation_strings":["Carna Biosciences, Inc., Hyogo, 650-0047, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Carna Biosciences, Inc., Hyogo, 650-0047, Japan","institution_ids":["https://openalex.org/I4405285453"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021970932","display_name":"Takayoshi Kinoshita","orcid":"https://orcid.org/0000-0003-2850-5409","observed_orcids":["https://orcid.org/0000-0003-2850-5409"]},"institutions":[{"id":"https://openalex.org/I4387152983","display_name":"Osaka Metropolitan University","ror":"https://ror.org/01hvx5h04","country_code":"JP","type":"education","lineage":["https://openalex.org/I4387152983"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T. Kinoshita","raw_affiliation_strings":["Graduate School of Science, Osaka Metropolitan University, 1-1 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8531, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Science, Osaka Metropolitan University, 1-1 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8531, Japan","institution_ids":["https://openalex.org/I4387152983"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4220,"currency":"USD","value_usd":4220},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.12250967,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"79","issue":"a2","first_page":"C869","last_page":"C869"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.8154000043869019,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.8154000043869019,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.1632000058889389,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.005499999970197678,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/molecular-dynamics-simulation","display_name":"molecular dynamics simulation","score":0.4880000054836273},{"id":"https://openalex.org/keywords/protein-conformational-dynamics","display_name":"protein conformational dynamics","score":0.6169999837875366},{"id":"https://openalex.org/keywords/protein-flexibility","display_name":"protein flexibility","score":0.6309999823570251},{"id":"https://openalex.org/keywords/protein-structure-function-relationship","display_name":"protein structure-function relationship","score":0.5389999747276306}],"concepts":[{"id":"https://openalex.org/C2780791683","wikidata":"https://www.wikidata.org/wiki/Q846785","display_name":"Action (physics)","level":2,"score":0.685772716999054},{"id":"https://openalex.org/C2780226923","wikidata":"https://www.wikidata.org/wiki/Q929848","display_name":"Movement (music)","level":2,"score":0.5079787373542786},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.43910109996795654},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.34520959854125977},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3179120421409607},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2716400623321533},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2519260346889496},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13713067770004272},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0684114396572113},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1107/s2053273323087521","doi":"https://doi.org/10.1107/s2053273323087521","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1107/s2053273323087521","pdf_url":null,"source":{"id":"https://openalex.org/S4393918093","display_name":"Acta Crystallographica Section A Foundations and Advances","issn_l":"2053-2733","issn":["2053-2733"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","norway-1","poland-200","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Crystallographica Section A Foundations and Advances","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":2,"referenced_works":["https://openalex.org/W1981346588","https://openalex.org/W2981318050"],"related_works":["https://openalex.org/W2037023383","https://openalex.org/W2010708479","https://openalex.org/W4254912320","https://openalex.org/W6920338031","https://openalex.org/W2079937255","https://openalex.org/W2053798195","https://openalex.org/W7095318593","https://openalex.org/W2763454674","https://openalex.org/W34889195","https://openalex.org/W1992945955"],"abstract_inverted_index":{"The":[0],"expression":[1],"of":[2,13],"protein":[3],"function":[4],"in":[5],"solution":[6],"is":[7],"closely":[8],"related":[9],"to":[10],"the":[11,28],"formation":[12],"its":[14,21],"unique":[15],"and":[16,20,31],"complex":[17],"three-dimensional":[18],"structure":[19],"flexible":[22],"but":[23],"regulated":[24],"movements":[25],"dictated":[26],"by":[27],"primary":[29],"sequence":[30],"given":[32],"environment.":[33]},"counts_by_year":[],"updated_date":"2026-10-09T09:14:12.587421","created_date":"2024-05-11T00:00:00"}