{"id":"https://openalex.org/W4396815112","doi":"https://doi.org/10.1093/ntr/ntae102","title":"The Effects of Changes in Cigarette Menthol Content on Acute Nicotine Pharmacology and Smoking Topography","display_name":"The Effects of Changes in Cigarette Menthol Content on Acute Nicotine Pharmacology and Smoking Topography","publication_year":2024,"publication_date":"2024-05-10","ids":{"openalex":"https://openalex.org/W4396815112","doi":"https://doi.org/10.1093/ntr/ntae102","pmid":"https://pubmed.ncbi.nlm.nih.gov/38728416"},"language":"en","primary_location":{"id":"doi:10.1093/ntr/ntae102","doi":"https://doi.org/10.1093/ntr/ntae102","is_oa":false,"landing_page_url":"https://doi.org/10.1093/ntr/ntae102","pdf_url":null,"source":{"id":"https://openalex.org/S62426309","display_name":"Nicotine & Tobacco Research","issn_l":"1462-2203","issn":["1462-2203","1469-994X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nicotine and Tobacco Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013347455","display_name":"Hristina Dimova","orcid":"https://orcid.org/0009-0007-9850-3608","observed_orcids":["https://orcid.org/0009-0007-9850-3608"]},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I4405263248","display_name":"Center for Tobacco Products","ror":"https://ror.org/04c42gq36","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I4405263248"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hristina Dimova","raw_affiliation_strings":["Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD ,","Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD , USA"],"raw_orcid":"https://orcid.org/0009-0007-9850-3608","affiliations":[{"raw_affiliation_string":"Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD ,","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I4405263248"]},{"raw_affiliation_string":"Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD , USA","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I4405263248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001486165","display_name":"Megan J. Schroeder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I4405263248","display_name":"Center for Tobacco Products","ror":"https://ror.org/04c42gq36","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I4405263248"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Megan J Schroeder","raw_affiliation_strings":["Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD ,","Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD ,","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I4405263248"]},{"raw_affiliation_string":"Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD , USA","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I4405263248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088899243","display_name":"Wallace B. Pickworth","orcid":"https://orcid.org/0000-0003-3310-2567","observed_orcids":["https://orcid.org/0000-0003-3310-2567"]},"institutions":[{"id":"https://openalex.org/I1325736334","display_name":"Battelle","ror":"https://ror.org/01h5tnr73","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1325736334"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wallace B Pickworth","raw_affiliation_strings":["Battelle Center for Public Health Research , Baltimore, MD ,","Battelle Center for Public Health Research , Baltimore, MD , USA"],"raw_orcid":"https://orcid.org/0000-0003-3310-2567","affiliations":[{"raw_affiliation_string":"Battelle Center for Public Health Research , Baltimore, MD ,","institution_ids":["https://openalex.org/I1325736334"]},{"raw_affiliation_string":"Battelle Center for Public Health Research , Baltimore, MD , USA","institution_ids":["https://openalex.org/I1325736334"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jia Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I4405263248","display_name":"Center for Tobacco Products","ror":"https://ror.org/04c42gq36","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I4405263248"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jia Wang","raw_affiliation_strings":["Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD ,","Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD ,","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I4405263248"]},{"raw_affiliation_string":"Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD , USA","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I4405263248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027204698","display_name":"Olusola Oniyide","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I4405263248","display_name":"Center for Tobacco Products","ror":"https://ror.org/04c42gq36","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I4405263248"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olusola Oniyide","raw_affiliation_strings":["Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD ,","Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD ,","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I4405263248"]},{"raw_affiliation_string":"Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD , USA","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I4405263248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064497198","display_name":"Lauren C. Viray","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1325736334","display_name":"Battelle","ror":"https://ror.org/01h5tnr73","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1325736334"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lauren C Viray","raw_affiliation_strings":["Battelle Center for Public Health Research , Baltimore, MD ,","Battelle Center for Public Health Research , Baltimore, MD , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Battelle Center for Public Health Research , Baltimore, MD ,","institution_ids":["https://openalex.org/I1325736334"]},{"raw_affiliation_string":"Battelle Center for Public Health Research , Baltimore, MD , USA","institution_ids":["https://openalex.org/I1325736334"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089910751","display_name":"Carson Smith","orcid":"https://orcid.org/0000-0002-1308-3437","observed_orcids":["https://orcid.org/0000-0002-1308-3437"]},"institutions":[{"id":"https://openalex.org/I1325736334","display_name":"Battelle","ror":"https://ror.org/01h5tnr73","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1325736334"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carson Smith","raw_affiliation_strings":["Battelle Center for Public Health Research , Baltimore, MD ,","Battelle Center for Public Health Research , Baltimore, MD , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Battelle Center for Public Health Research , Baltimore, MD ,","institution_ids":["https://openalex.org/I1325736334"]},{"raw_affiliation_string":"Battelle Center for Public Health Research , Baltimore, MD , USA","institution_ids":["https://openalex.org/I1325736334"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048194451","display_name":"Bartosz Koszowski","orcid":"https://orcid.org/0000-0002-7929-7040","observed_orcids":["https://orcid.org/0000-0002-7929-7040"]},"institutions":[{"id":"https://openalex.org/I1325736334","display_name":"Battelle","ror":"https://ror.org/01h5tnr73","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1325736334"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bartosz Koszowski","raw_affiliation_strings":["Battelle Center for Public Health Research , Baltimore, MD ,","Battelle Center for Public Health Research , Baltimore, MD , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Battelle Center for Public Health Research , Baltimore, MD ,","institution_ids":["https://openalex.org/I1325736334"]},{"raw_affiliation_string":"Battelle Center for Public Health Research , Baltimore, MD , USA","institution_ids":["https://openalex.org/I1325736334"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081095090","display_name":"Kia J. Jackson","orcid":"https://orcid.org/0000-0002-3913-8774","observed_orcids":["https://orcid.org/0000-0002-3913-8774"]},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I4405263248","display_name":"Center for Tobacco Products","ror":"https://ror.org/04c42gq36","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I4405263248"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kia J Jackson","raw_affiliation_strings":["Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD ,","Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD , USA"],"raw_orcid":"https://orcid.org/0000-0002-3913-8774","affiliations":[{"raw_affiliation_string":"Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD ,","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I4405263248"]},{"raw_affiliation_string":"Food and Drug Administration, Center for Tobacco Products, Office of Science , Calverton, MD , USA","institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I4405263248"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5013347455"],"corresponding_institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I4405263248"],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":null,"fwci":0.7535,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.70035799,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":"27","issue":"4","first_page":"676","last_page":"683"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11818","display_name":"Nicotinic Acetylcholine Receptors Study","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nicotine-pharmacokinetics","display_name":"nicotine pharmacokinetics","score":0.9520000219345093},{"id":"https://openalex.org/keywords/smoking-topography","display_name":"smoking topography","score":0.972000002861023},{"id":"https://openalex.org/keywords/puff-volume","display_name":"puff volume","score":0.8379999995231628},{"id":"https://openalex.org/keywords/puff-duration","display_name":"puff duration","score":0.9800000190734863},{"id":"https://openalex.org/keywords/cigarette-flavor","display_name":"cigarette flavor","score":0.35199999809265137},{"id":"https://openalex.org/keywords/tobacco-dependence","display_name":"tobacco dependence","score":0.44200000166893005}],"concepts":[{"id":"https://openalex.org/C2780194911","wikidata":"https://www.wikidata.org/wiki/Q407418","display_name":"Menthol","level":2,"score":0.9918367862701416},{"id":"https://openalex.org/C2779547902","wikidata":"https://www.wikidata.org/wiki/Q28086552","display_name":"Nicotine","level":2,"score":0.802056074142456},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5356390476226807},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4626854658126831},{"id":"https://openalex.org/C2777843972","wikidata":"https://www.wikidata.org/wiki/Q2462253","display_name":"Smoking cessation","level":2,"score":0.4553168714046478},{"id":"https://openalex.org/C3019085024","wikidata":"https://www.wikidata.org/wiki/Q7212330","display_name":"Cigarette smoking","level":2,"score":0.4243907928466797},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3877367377281189},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2692965269088745},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18194806575775146},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000073865","descriptor_name":"Cigarette Smoking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008610","descriptor_name":"Menthol","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D008610","descriptor_name":"Menthol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009538","descriptor_name":"Nicotine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D009538","descriptor_name":"Nicotine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009538","descriptor_name":"Nicotine","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D009538","descriptor_name":"Nicotine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062789","descriptor_name":"Tobacco Products","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/ntr/ntae102","doi":"https://doi.org/10.1093/ntr/ntae102","is_oa":false,"landing_page_url":"https://doi.org/10.1093/ntr/ntae102","pdf_url":null,"source":{"id":"https://openalex.org/S62426309","display_name":"Nicotine & Tobacco Research","issn_l":"1462-2203","issn":["1462-2203","1469-994X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nicotine and Tobacco Research","raw_type":"journal-article"},{"id":"pmid:38728416","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38728416","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[{"id":"https://openalex.org/G5405903729","display_name":null,"funder_award_id":"HHSF223201310030I","funder_id":"https://openalex.org/F4320332163","funder_display_name":"U.S. Food and Drug Administration"}],"funders":[{"id":"https://openalex.org/F4320332163","display_name":"U.S. Food and Drug Administration","ror":"https://ror.org/034xvzb47"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W2000115175","https://openalex.org/W2008915389","https://openalex.org/W2023196630","https://openalex.org/W2038953203","https://openalex.org/W2039460330","https://openalex.org/W2043177796","https://openalex.org/W2045213593","https://openalex.org/W2046138823","https://openalex.org/W2048270309","https://openalex.org/W2048458691","https://openalex.org/W2057143460","https://openalex.org/W2110569081","https://openalex.org/W2114694355","https://openalex.org/W2116257115","https://openalex.org/W2122742701","https://openalex.org/W2139363119","https://openalex.org/W2143512547","https://openalex.org/W2591148380","https://openalex.org/W2613065743","https://openalex.org/W2803636644","https://openalex.org/W2967703795","https://openalex.org/W2982745436","https://openalex.org/W2997588983","https://openalex.org/W2998871912","https://openalex.org/W3023925477","https://openalex.org/W3092915647","https://openalex.org/W3095589803","https://openalex.org/W3161470358","https://openalex.org/W3181528964","https://openalex.org/W4318264115"],"related_works":["https://openalex.org/W4410186736","https://openalex.org/W2048595857","https://openalex.org/W2745098681","https://openalex.org/W2803636644","https://openalex.org/W2239614844","https://openalex.org/W2084736423","https://openalex.org/W2000115175","https://openalex.org/W2061643560","https://openalex.org/W4407894161","https://openalex.org/W2518165853"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Menthol":[1],"influences":[2],"the":[3,11,28,59,159,180,190,195,206,219,276],"appeal":[4],"and":[5,20,38,71,80,103,155,170,183,203,281,287,299],"addictiveness":[6],"of":[7,30,61,91,100,130,138,278],"cigarette":[8,32,199],"smoking,":[9,147],"however":[10],"data":[12,253,274],"regarding":[13],"menthol's":[14,279],"effects":[15,60,82,268,283],"on":[16,35,75,132,239,265],"nicotine":[17,36,76,133,240],"pharmacokinetics":[18],"(PK)":[19],"smoking":[21,39,62,78,102,108,115,137,227,243,289],"topography":[22,40,116,122,244],"are":[23],"inconsistent.":[24],"This":[25],"study":[26,49,56],"investigated":[27],"impact":[29,264],"different":[31],"menthol":[33,43,66,85,131,142,162,167,186,193,198,230,257],"levels":[34],"pharmacology":[37],"in":[41,83,158,245],"current":[42,84],"smokers.":[44,86],"AIMS":[45],"AND":[46],"METHODS:":[47],"The":[48],"was":[50,117,126,149,200],"a":[51,92,104,236,262],"double-blind,":[52],"randomized,":[53],"four-period,":[54],"crossover":[55],"to":[57,165,189,224,284,296],"investigate":[58],"cigarettes":[63,139,187],"with":[64,140],"varying":[65,141,256],"content":[67,258],"(0,":[68],"3,":[69],"6,":[70],"12":[72,160,196],"mg":[73,161,182,185,192,197,208],"menthol)":[74],"PK,":[77],"topography,":[79],"subjective":[81,226],"Each":[87],"experimental":[88],"session":[89],"consisted":[90],"prescribed":[93,136],"use":[94],"session,":[95],"followed":[96],"by":[97],"145":[98],"min":[99],"no":[101,127],"1-h":[105],"ad":[106,145],"libitum":[107,146],"session.":[109],"Serial":[110],"blood":[111],"samples":[112],"were":[113],"collected;":[114],"recorded":[118],"using":[119],"CReSS":[120],"Lab":[121],"device.":[123],"RESULTS:":[124],"There":[125],"significant":[128,237,263],"effect":[129,238],"PK":[134,241],"after":[135],"contents.":[143],"During":[144],"there":[148],"significantly":[150,174],"smaller":[151],"total":[152],"puff":[153,156],"volume":[154],"duration":[157],"condition":[163],"compared":[164,188],"other":[166],"conditions.":[168],"Subjective":[169],"sensory":[171,282],"measures":[172],"indicated":[173],"higher":[175],"overall":[176],"positive":[177,225,288],"ratings":[178],"for":[179],"3":[181,207],"6":[184],"0":[191],"cigarette;":[194],"less":[201],"liked":[202],"harsher":[204],"than":[205],"condition.":[209],"CONCLUSIONS:":[210],"These":[211],"findings":[212],"suggest":[213],"that":[214,255],"menthol,":[215],"at":[216],"concentrations":[217],"reflecting":[218],"marketplace":[220],"(3-6":[221],"mg),":[222],"contributes":[223],"experiences":[228],"among":[229],"smokers,":[231],"but":[232],"does":[233,259],"not":[234,260],"have":[235,261],"or":[242],"an":[246],"acute":[247,270],"laboratory":[248],"setting.":[249],"IMPLICATIONS:":[250],"While":[251],"our":[252],"indicate":[254],"nicotine's":[266],"pharmacological":[267],"under":[269],"exposure":[271],"conditions,":[272],"these":[273],"highlight":[275],"contribution":[277],"flavor":[280],"product":[285],"preference":[286],"experiences,":[290],"which":[291],"facilitate":[292],"repeated":[293],"experimentation,":[294],"progression":[295],"regular":[297],"use,":[298],"subsequent":[300],"dependence.":[301]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2024-05-11T00:00:00"}