{"id":"https://openalex.org/W4396712802","doi":"https://doi.org/10.1615/intjmedmushrooms.2024053946","title":"Oral Administration of Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Extract Protects Gingival Tissues against Proinflammatory TNF-\u03b1 and Oxidative Stress in Periodontitis Model Rats","display_name":"Oral Administration of Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Extract Protects Gingival Tissues against Proinflammatory TNF-\u03b1 and Oxidative Stress in Periodontitis Model Rats","publication_year":2024,"publication_date":"2024-01-01","ids":{"openalex":"https://openalex.org/W4396712802","doi":"https://doi.org/10.1615/intjmedmushrooms.2024053946","pmid":"https://pubmed.ncbi.nlm.nih.gov/38967207"},"language":"en","primary_location":{"id":"doi:10.1615/intjmedmushrooms.2024053946","doi":"https://doi.org/10.1615/intjmedmushrooms.2024053946","is_oa":false,"landing_page_url":"https://doi.org/10.1615/intjmedmushrooms.2024053946","pdf_url":null,"source":{"id":"https://openalex.org/S79925788","display_name":"International journal of medicinal mushrooms","issn_l":"1521-9437","issn":["1521-9437","1940-4344"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315730","host_organization_name":"Begell House","host_organization_lineage":["https://openalex.org/P4310315730"],"host_organization_lineage_names":["Begell House"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medicinal Mushrooms","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032896005","display_name":"Shahdat Hossain","orcid":"https://orcid.org/0000-0003-2970-2324","observed_orcids":["https://orcid.org/0000-0003-2970-2324"]},"institutions":[{"id":"https://openalex.org/I46080048","display_name":"Jahangirnagar University","ror":"https://ror.org/04ywb0864","country_code":"BD","type":"education","lineage":["https://openalex.org/I46080048"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Shahdat Hossain","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka, Bangladesh","Jahangirnagar University,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka, Bangladesh","institution_ids":["https://openalex.org/I46080048"]},{"raw_affiliation_string":"Jahangirnagar University,","institution_ids":["https://openalex.org/I46080048"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100666248","display_name":"Mohammad Azizur Rahman","orcid":"https://orcid.org/0000-0002-3113-0313","observed_orcids":["https://orcid.org/0000-0002-3113-0313","https://orcid.org/0000-0003-4322-8219"]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]},{"id":"https://openalex.org/I46080048","display_name":"Jahangirnagar University","ror":"https://ror.org/04ywb0864","country_code":"BD","type":"education","lineage":["https://openalex.org/I46080048"]}],"countries":["BD","MY"],"is_corresponding":true,"raw_author_name":"Mohammad Azizur Rahman","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh; Mushroom Research Centre, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia","Jahangirnagar University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh; Mushroom Research Centre, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I33849332","https://openalex.org/I46080048"]},{"raw_affiliation_string":"Jahangirnagar University","institution_ids":["https://openalex.org/I46080048"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009264963","display_name":"Borhan Uddin","orcid":"https://orcid.org/0000-0001-9142-7568","observed_orcids":["https://orcid.org/0000-0001-9142-7568"]},"institutions":[{"id":"https://openalex.org/I46080048","display_name":"Jahangirnagar University","ror":"https://ror.org/04ywb0864","country_code":"BD","type":"education","lineage":["https://openalex.org/I46080048"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Borhan Uddin","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh","Jahangirnagar University,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh","institution_ids":["https://openalex.org/I46080048"]},{"raw_affiliation_string":"Jahangirnagar University,","institution_ids":["https://openalex.org/I46080048"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079515831","display_name":"Taslima Nahar","orcid":"https://orcid.org/0000-0002-9804-7565","observed_orcids":["https://orcid.org/0000-0002-9804-7565"]},"institutions":[{"id":"https://openalex.org/I46080048","display_name":"Jahangirnagar University","ror":"https://ror.org/04ywb0864","country_code":"BD","type":"education","lineage":["https://openalex.org/I46080048"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Taslima Nahar","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh","Jahangirnagar University,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh","institution_ids":["https://openalex.org/I46080048"]},{"raw_affiliation_string":"Jahangirnagar University,","institution_ids":["https://openalex.org/I46080048"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000660890","display_name":"Marzan Sarkar","orcid":"https://orcid.org/0000-0003-0047-1841","observed_orcids":["https://orcid.org/0000-0003-0047-1841"]},"institutions":[{"id":"https://openalex.org/I46080048","display_name":"Jahangirnagar University","ror":"https://ror.org/04ywb0864","country_code":"BD","type":"education","lineage":["https://openalex.org/I46080048"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Marzan Sarkar","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh","Jahangirnagar University,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh","institution_ids":["https://openalex.org/I46080048"]},{"raw_affiliation_string":"Jahangirnagar University,","institution_ids":["https://openalex.org/I46080048"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113242522","display_name":"Shoriful Islam Joy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I46080048","display_name":"Jahangirnagar University","ror":"https://ror.org/04ywb0864","country_code":"BD","type":"education","lineage":["https://openalex.org/I46080048"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Shoriful Islam Joy","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh","Jahangirnagar University,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh","institution_ids":["https://openalex.org/I46080048"]},{"raw_affiliation_string":"Jahangirnagar University,","institution_ids":["https://openalex.org/I46080048"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5099042429","display_name":"Anuradha Baraik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I46080048","display_name":"Jahangirnagar University","ror":"https://ror.org/04ywb0864","country_code":"BD","type":"education","lineage":["https://openalex.org/I46080048"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Anuradha Baraik","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh","institution_ids":["https://openalex.org/I46080048"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100666248"],"corresponding_institution_ids":["https://openalex.org/I33849332","https://openalex.org/I46080048"],"apc_list":null,"apc_paid":null,"fwci":0.4201,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.55088549,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":96},"biblio":{"volume":"26","issue":"8","first_page":"1","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11085","display_name":"Fungal Biology and Applications","score":0.8970000147819519,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11085","display_name":"Fungal Biology and Applications","score":0.8970000147819519,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.09399999678134918,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12087","display_name":"Natural Compound Pharmacology Studies","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ganoderma-lucidum","display_name":"Ganoderma lucidum","score":0.9990000128746033},{"id":"https://openalex.org/keywords/periodontitis","display_name":"periodontitis","score":0.996999979019165},{"id":"https://openalex.org/keywords/gingiva","display_name":"gingiva","score":0.828000009059906},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9639999866485596},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8859999775886536},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/free-radical-scavenging-activity","display_name":"free radical scavenging","score":0.7829999923706055},{"id":"https://openalex.org/keywords/polyphenols","display_name":"polyphenols","score":0.9660000205039978},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":1.0},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.7400000095367432},{"id":"https://openalex.org/keywords/oral-administration","display_name":"oral administration","score":0.5260000228881836},{"id":"https://openalex.org/keywords/fenton-s-reagent","display_name":"Fenton reagent","score":0.5210000276565552}],"concepts":[{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.816514253616333},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6534895896911621},{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.6458852291107178},{"id":"https://openalex.org/C2781401929","wikidata":"https://www.wikidata.org/wiki/Q5205953","display_name":"DPPH","level":3,"score":0.6399267911911011},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.6284686326980591},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.603813648223877},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5934380888938904},{"id":"https://openalex.org/C2780385504","wikidata":"https://www.wikidata.org/wiki/Q520127","display_name":"Periodontitis","level":2,"score":0.5933701992034912},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.5129101276397705},{"id":"https://openalex.org/C70899900","wikidata":"https://www.wikidata.org/wiki/Q290439","display_name":"Polyphenol","level":3,"score":0.48841923475265503},{"id":"https://openalex.org/C2777056448","wikidata":"https://www.wikidata.org/wiki/Q285166","display_name":"Oral administration","level":2,"score":0.45602577924728394},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.3484777808189392},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.33873307704925537},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21767175197601318},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14586976170539856},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.13180238008499146},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.1272360384464264},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11554896831512451},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005881","descriptor_name":"Gingiva","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005881","descriptor_name":"Gingiva","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010518","descriptor_name":"Periodontitis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010518","descriptor_name":"Periodontitis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D020940","descriptor_name":"Reishi","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1615/intjmedmushrooms.2024053946","doi":"https://doi.org/10.1615/intjmedmushrooms.2024053946","is_oa":false,"landing_page_url":"https://doi.org/10.1615/intjmedmushrooms.2024053946","pdf_url":null,"source":{"id":"https://openalex.org/S79925788","display_name":"International journal of medicinal mushrooms","issn_l":"1521-9437","issn":["1521-9437","1940-4344"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315730","host_organization_name":"Begell House","host_organization_lineage":["https://openalex.org/P4310315730"],"host_organization_lineage_names":["Begell House"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medicinal Mushrooms","raw_type":"journal-article"},{"id":"pmid:38967207","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38967207","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of medicinal mushrooms","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W111029014","https://openalex.org/W637283775","https://openalex.org/W1537580506","https://openalex.org/W1605160020","https://openalex.org/W1964544797","https://openalex.org/W1966571453","https://openalex.org/W1976102373","https://openalex.org/W1979521647","https://openalex.org/W1983759074","https://openalex.org/W1994080141","https://openalex.org/W1994210016","https://openalex.org/W1994780675","https://openalex.org/W1994893732","https://openalex.org/W1997834526","https://openalex.org/W1998074008","https://openalex.org/W2005502331","https://openalex.org/W2013190478","https://openalex.org/W2013203343","https://openalex.org/W2016304906","https://openalex.org/W2025703430","https://openalex.org/W2031554637","https://openalex.org/W2036932056","https://openalex.org/W2038843858","https://openalex.org/W2040332366","https://openalex.org/W2044063767","https://openalex.org/W2044708675","https://openalex.org/W2064097304","https://openalex.org/W2064139379","https://openalex.org/W2071456152","https://openalex.org/W2078811399","https://openalex.org/W2084299658","https://openalex.org/W2086033902","https://openalex.org/W2086588624","https://openalex.org/W2086994832","https://openalex.org/W2091415746","https://openalex.org/W2091831612","https://openalex.org/W2127632638","https://openalex.org/W2128632938","https://openalex.org/W2131684681","https://openalex.org/W2151309337","https://openalex.org/W2158535716","https://openalex.org/W2171105146","https://openalex.org/W2244476521","https://openalex.org/W2327828180","https://openalex.org/W2334922036","https://openalex.org/W2505865713","https://openalex.org/W3137579289","https://openalex.org/W4386929382"],"related_works":["https://openalex.org/W4401231504","https://openalex.org/W3140196010","https://openalex.org/W2064461800","https://openalex.org/W1979813841","https://openalex.org/W4402949871","https://openalex.org/W7154454856","https://openalex.org/W2020237089","https://openalex.org/W2372461930","https://openalex.org/W2024381657","https://openalex.org/W4362657667"],"abstract_inverted_index":{"Ganoderma":[0],"lucidum":[1,21,48,84,108,128,148,183,199],"is":[2,208],"a":[3],"medicinal":[4],"mushroom":[5],"that":[6],"has":[7],"been":[8],"used":[9],"since":[10],"ancient":[11],"times.":[12],"We":[13],"studied":[14],"whether":[15],"chronic":[16],"oral":[17,104],"administration":[18,105],"of":[19,27,36,43,55,67,106,123,144,153,168,178,197,205],"G.":[20,47,83,107,127,147,182,198],"extract":[22,49,85,109,129],"withstands":[23],"increases":[24],"in":[25,39,56,64,75,78,119,135,146,157,165,181],"levels":[26,118,143],"proinflammatory":[28],"TNF-\u03b1":[29,115],"and":[30,77,96,116,175,213],"lipid":[31,169],"peroxide":[32],"(LPO),":[33],"an":[34,202],"indicator":[35],"oxidative":[37,58,137,211],"stress,":[38,59,138],"the":[40,120,164,176,188,194],"gingival":[41,121],"tissues":[42,70,122],"periodontitis":[44,124],"model":[45,125],"rats.":[46,72,126,155],"was":[50,86],"initially":[51],"examined":[52],"for":[53,89,193],"inhibition":[54,167],"vitro":[57,79,136,158],"produced":[60],"by":[61,141,215],"Fenton's":[62],"reagents":[63],"whole":[65],"homogenates":[66,152],"fresh":[68,154],"gum":[69,150,217],"from":[71],"Prior":[73],"to":[74,98],"vivo":[76,166],"experiments":[80],"with":[81,163,210],"rats,":[82],"quantitatively":[87],"tested":[88],"its":[90],"total":[91,179],"polyphenol":[92],"and/or":[93],"flavonoid":[94],"contents":[95],"ability":[97],"scavenge":[99],"2,2-diphenyl-1-picrylhydrazyl":[100],"(DPPH)-free":[101],"radicals.":[102],"Chronic":[103],"(300":[110],"mg/kg":[111],"BW)":[112],"significantly":[113],"decreased":[114],"LPO":[117,145],"also":[130],"inhibited":[131],"(P":[132],"<":[133],"0.05)":[134],"as":[139],"indicated":[140],"reduced":[142],"extract-preincubated":[149],"tissue":[151],"The":[156],"results":[159,186],"were,":[160],"thus,":[161],"consistent":[162],"peroxidation,":[170],"DPPH":[171],"free":[172],"radical-scavenging":[173],"effects,":[174],"presence":[177],"polyphenols/flavonoids":[180],"extract.":[184],"Our":[185],"provide":[187],"evidence,":[189],"at":[190],"least":[191],"partially,":[192],"beneficial":[195],"effects":[196],"on":[200],"periodontitis,":[201],"inflammatory":[203],"condition":[204],"gums":[206],"which":[207],"associated":[209],"stress":[212],"preceded":[214],"infectious":[216],"diseases.":[218]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-05-08T00:00:00"}