{"id":"https://openalex.org/W4396618581","doi":"https://doi.org/10.1016/j.ajpath.2024.04.005","title":"Dysregulation of the Long Noncoding RNA X-Inactive\u2013Specific Transcript Expression in Male Patients with Pulmonary Arterial Hypertension","display_name":"Dysregulation of the Long Noncoding RNA X-Inactive\u2013Specific Transcript Expression in Male Patients with Pulmonary Arterial Hypertension","publication_year":2024,"publication_date":"2024-05-03","ids":{"openalex":"https://openalex.org/W4396618581","doi":"https://doi.org/10.1016/j.ajpath.2024.04.005","pmid":"https://pubmed.ncbi.nlm.nih.gov/38705381","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11284765"},"language":"en","primary_location":{"id":"doi:10.1016/j.ajpath.2024.04.005","doi":"https://doi.org/10.1016/j.ajpath.2024.04.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ajpath.2024.04.005","pdf_url":"https://ajp.amjpathol.org/article/S0002-9440(24)00166-4/pdf","source":{"id":"https://openalex.org/S145577119","display_name":"American Journal Of Pathology","issn_l":"0002-9440","issn":["0002-9440","1525-2191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Pathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://ajp.amjpathol.org/article/S0002-9440(24)00166-4/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076478044","display_name":"Brandon L. Carman","orcid":"https://orcid.org/0000-0002-3556-3730","observed_orcids":["https://orcid.org/0000-0002-3556-3730"]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brandon L. Carman","raw_affiliation_strings":["Division of Pulmonary, Critical Care and Sleep Medicine, Rush University Medical Center, Chicago, Illinois"],"raw_orcid":"https://orcid.org/0000-0002-3556-3730","affiliations":[{"raw_affiliation_string":"Division of Pulmonary, Critical Care and Sleep Medicine, Rush University Medical Center, Chicago, Illinois","institution_ids":["https://openalex.org/I1285301757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013279525","display_name":"Shanshan Qin","orcid":"https://orcid.org/0000-0002-8527-5278","observed_orcids":["https://orcid.org/0000-0002-8527-5278"]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shanshan Qin","raw_affiliation_strings":["Division of Pulmonary, Critical Care and Sleep Medicine, Rush University Medical Center, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pulmonary, Critical Care and Sleep Medicine, Rush University Medical Center, Chicago, Illinois","institution_ids":["https://openalex.org/I1285301757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113547810","display_name":"Dan N. Predescu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dan N. Predescu","raw_affiliation_strings":["Division of Pulmonary, Critical Care and Sleep Medicine, Rush University Medical Center, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pulmonary, Critical Care and Sleep Medicine, Rush University Medical Center, Chicago, Illinois","institution_ids":["https://openalex.org/I1285301757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112402008","display_name":"Malabendu Jana","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Malabendu Jana","raw_affiliation_strings":["Department of Neurological Science, Rush University Medical Center, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurological Science, Rush University Medical Center, Chicago, Illinois","institution_ids":["https://openalex.org/I1285301757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060586492","display_name":"Rene Cortese","orcid":"https://orcid.org/0000-0001-9262-7828","observed_orcids":["https://orcid.org/0000-0001-9262-7828"]},"institutions":[{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rene Cortese","raw_affiliation_strings":["Child Health Research Institute, University of Missouri, Columbia, Missouri"],"raw_orcid":"https://orcid.org/0000-0001-9262-7828","affiliations":[{"raw_affiliation_string":"Child Health Research Institute, University of Missouri, Columbia, Missouri","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008186721","display_name":"Micheala A. Aldred","orcid":"https://orcid.org/0000-0002-7390-9181","observed_orcids":["https://orcid.org/0000-0002-7390-9181"]},"institutions":[{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]},{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Micheala A. Aldred","raw_affiliation_strings":["Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Indiana University School of Medicine, Indianapolis, Indiana"],"raw_orcid":"https://orcid.org/0000-0002-7390-9181","affiliations":[{"raw_affiliation_string":"Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Indiana University School of Medicine, Indianapolis, Indiana","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130","https://openalex.org/I55769427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043623030","display_name":"David Gozal","orcid":"https://orcid.org/0000-0001-8195-6036","observed_orcids":["https://orcid.org/0000-0001-8195-6036"]},"institutions":[{"id":"https://openalex.org/I88694374","display_name":"Marshall University","ror":"https://ror.org/02erqft81","country_code":"US","type":"education","lineage":["https://openalex.org/I88694374"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Gozal","raw_affiliation_strings":["Joan C. Edwards School of Medicine, Marshall University, Huntington, West Virginia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Joan C. Edwards School of Medicine, Marshall University, Huntington, West Virginia","institution_ids":["https://openalex.org/I88694374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068088647","display_name":"Babak Mokhlesi","orcid":"https://orcid.org/0000-0001-8135-5433","observed_orcids":["https://orcid.org/0000-0001-8135-5433"]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Babak Mokhlesi","raw_affiliation_strings":["Division of Pulmonary, Critical Care and Sleep Medicine, Rush University Medical Center, Chicago, Illinois"],"raw_orcid":"https://orcid.org/0000-0001-8135-5433","affiliations":[{"raw_affiliation_string":"Division of Pulmonary, Critical Care and Sleep Medicine, Rush University Medical Center, Chicago, Illinois","institution_ids":["https://openalex.org/I1285301757"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072522825","display_name":"Sanda A. Predescu","orcid":"https://orcid.org/0000-0002-9386-6756","observed_orcids":["https://orcid.org/0000-0002-9386-6756"]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sanda A. Predescu","raw_affiliation_strings":["Division of Pulmonary, Critical Care and Sleep Medicine, Rush University Medical Center, Chicago, Illinois. Electronic address: sanda_predescu@rush.edu"],"raw_orcid":"https://orcid.org/0000-0002-9386-6756","affiliations":[{"raw_affiliation_string":"Division of Pulmonary, Critical Care and Sleep Medicine, Rush University Medical Center, Chicago, Illinois. Electronic address: sanda_predescu@rush.edu","institution_ids":["https://openalex.org/I1285301757"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5072522825"],"corresponding_institution_ids":["https://openalex.org/I1285301757"],"apc_list":{"value":2800,"currency":"USD","value_usd":2800},"apc_paid":null,"fwci":3.7748,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.94047258,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"194","issue":"8","first_page":"1592","last_page":"1606"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pulmonary-arterial-hypertension","display_name":"pulmonary arterial hypertension","score":0.9860000014305115},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.4860000014305115},{"id":"https://openalex.org/keywords/male-patients","display_name":"male patients","score":0.6859999895095825},{"id":"https://openalex.org/keywords/pulmonary-artery-endothelial-cells","display_name":"pulmonary artery endothelial cells","score":0.9079999923706055},{"id":"https://openalex.org/keywords/endothelial-cell-proliferation","display_name":"endothelial cell proliferation","score":0.9350000023841858},{"id":"https://openalex.org/keywords/klf2","display_name":"KLF2","score":0.625},{"id":"https://openalex.org/keywords/ezh2","display_name":"EZH2","score":0.9419999718666077},{"id":"https://openalex.org/keywords/polycomb-repressive-complex-2","display_name":"polycomb repressive complex 2","score":0.9679999947547913},{"id":"https://openalex.org/keywords/c-fos","display_name":"c-fos","score":0.8140000104904175},{"id":"https://openalex.org/keywords/p38-mapk-signaling","display_name":"p38 MAPK signaling","score":0.8970000147819519},{"id":"https://openalex.org/keywords/cyclin-a1","display_name":"cyclin A1","score":0.7929999828338623},{"id":"https://openalex.org/keywords/cyclin-d2","display_name":"cyclin D2","score":0.9959999918937683},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.7459999918937683},{"id":"https://openalex.org/keywords/x-chromosome-inactivation","display_name":"X chromosome inactivation","score":0.875}],"concepts":[{"id":"https://openalex.org/C110411900","wikidata":"https://www.wikidata.org/wiki/Q18032385","display_name":"XIST","level":5,"score":0.7581070065498352},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.6925956606864929},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6512511372566223},{"id":"https://openalex.org/C2780930700","wikidata":"https://www.wikidata.org/wiki/Q1128595","display_name":"Pulmonary hypertension","level":2,"score":0.6187916398048401},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.5909216403961182},{"id":"https://openalex.org/C62203573","wikidata":"https://www.wikidata.org/wiki/Q15087973","display_name":"Long non-coding RNA","level":4,"score":0.49528828263282776},{"id":"https://openalex.org/C194993378","wikidata":"https://www.wikidata.org/wiki/Q427087","display_name":"Non-coding RNA","level":4,"score":0.4753439426422119},{"id":"https://openalex.org/C35158069","wikidata":"https://www.wikidata.org/wiki/Q61333","display_name":"X chromosome","level":3,"score":0.4288558065891266},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4174101650714874},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3731231093406677},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3528062701225281},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.31133610010147095},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.29992151260375977},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.25348764657974243},{"id":"https://openalex.org/C4323932","wikidata":"https://www.wikidata.org/wiki/Q898914","display_name":"X-inactivation","level":4,"score":0.24601009488105774}],"mesh":[{"descriptor_ui":"D000071221","descriptor_name":"Enhancer of Zeste Homolog 2 Protein","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000071221","descriptor_name":"Enhancer of Zeste Homolog 2 Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000081029","descriptor_name":"Pulmonary Arterial Hypertension","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000081029","descriptor_name":"Pulmonary Arterial Hypertension","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000081029","descriptor_name":"Pulmonary Arterial Hypertension","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011651","descriptor_name":"Pulmonary Artery","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011651","descriptor_name":"Pulmonary Artery","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D050807","descriptor_name":"ets-Domain Protein Elk-1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D050807","descriptor_name":"ets-Domain Protein Elk-1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051741","descriptor_name":"Kruppel-Like Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051741","descriptor_name":"Kruppel-Like Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.ajpath.2024.04.005","doi":"https://doi.org/10.1016/j.ajpath.2024.04.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ajpath.2024.04.005","pdf_url":"https://ajp.amjpathol.org/article/S0002-9440(24)00166-4/pdf","source":{"id":"https://openalex.org/S145577119","display_name":"American Journal Of Pathology","issn_l":"0002-9440","issn":["0002-9440","1525-2191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Pathology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11284765","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11284765","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11284765/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Pathol","raw_type":"Text"},{"id":"pmh:oai:europepmc.org:11121405","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11284765","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:38705381","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38705381","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of pathology","raw_type":"Journal Article"},{"id":"pmh:oai:scholarworks.indianapolis.iu.edu:1805/50880","doi":null,"is_oa":false,"landing_page_url":"https://scholarworks.indianapolis.iu.edu/bitstreams/bbaaedbf-9b83-44f1-ac7f-9c289928b561/download","pdf_url":null,"source":{"id":"https://openalex.org/S4306400987","display_name":"IUScholarWorks (Indiana University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I592451","host_organization_name":"Indiana University","host_organization_lineage":["https://openalex.org/I592451"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PMC","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1016/j.ajpath.2024.04.005","doi":"https://doi.org/10.1016/j.ajpath.2024.04.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ajpath.2024.04.005","pdf_url":"https://ajp.amjpathol.org/article/S0002-9440(24)00166-4/pdf","source":{"id":"https://openalex.org/S145577119","display_name":"American Journal Of Pathology","issn_l":"0002-9440","issn":["0002-9440","1525-2191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Pathology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3496267628","display_name":"Cleavage of intersectin-1s by Granzyme B and Pulmonary Arterial Hypertension","funder_award_id":"R01HL127022","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5707561111","display_name":"Nitric Oxide in Pulmonary Hypertension","funder_award_id":"R37HL060917","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7166330850","display_name":"Nitric Oxide in Pulmonary Hypertension","funder_award_id":"R01HL060917","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7366038496","display_name":"Pulmonary Hypertension Breakthrough Initiative","funder_award_id":"R24HL123767","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000176715","display_name":null,"funder_award_id":"HL 60917","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320309680","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83"},{"id":"https://openalex.org/F4320316601","display_name":"Cardiovascular Medical Research and Education Fund","ror":"https://ror.org/00f1t9w57"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320333295","display_name":"Lerner Research Institute, Cleveland Clinic","ror":null},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4396618581.pdf","grobid_xml":"https://content.openalex.org/works/W4396618581.grobid-xml"},"referenced_works_count":75,"referenced_works":["https://openalex.org/W78683901","https://openalex.org/W1967339226","https://openalex.org/W1978324852","https://openalex.org/W1993287655","https://openalex.org/W2000051774","https://openalex.org/W2008620032","https://openalex.org/W2025856640","https://openalex.org/W2029603032","https://openalex.org/W2038311789","https://openalex.org/W2038720675","https://openalex.org/W2041839333","https://openalex.org/W2050098287","https://openalex.org/W2050650803","https://openalex.org/W2052074936","https://openalex.org/W2059597936","https://openalex.org/W2061442012","https://openalex.org/W2061564804","https://openalex.org/W2069373787","https://openalex.org/W2071419761","https://openalex.org/W2090192743","https://openalex.org/W2097706430","https://openalex.org/W2114570899","https://openalex.org/W2117339256","https://openalex.org/W2118452945","https://openalex.org/W2122699022","https://openalex.org/W2129513537","https://openalex.org/W2130287279","https://openalex.org/W2147107152","https://openalex.org/W2156831603","https://openalex.org/W2162937290","https://openalex.org/W2165879832","https://openalex.org/W2166773371","https://openalex.org/W2168334038","https://openalex.org/W2194585464","https://openalex.org/W2264682687","https://openalex.org/W2460880027","https://openalex.org/W2479584244","https://openalex.org/W2493579771","https://openalex.org/W2508082015","https://openalex.org/W2509738156","https://openalex.org/W2512700670","https://openalex.org/W2520931866","https://openalex.org/W2531569648","https://openalex.org/W2540656623","https://openalex.org/W2571331043","https://openalex.org/W2583089302","https://openalex.org/W2592793288","https://openalex.org/W2616160118","https://openalex.org/W2620873905","https://openalex.org/W2621229357","https://openalex.org/W2731206995","https://openalex.org/W2794222785","https://openalex.org/W2795080192","https://openalex.org/W2807912841","https://openalex.org/W2808672927","https://openalex.org/W2810602324","https://openalex.org/W2888964175","https://openalex.org/W2909484927","https://openalex.org/W2912695998","https://openalex.org/W2940206963","https://openalex.org/W2945454095","https://openalex.org/W2995245904","https://openalex.org/W2995489031","https://openalex.org/W2999537752","https://openalex.org/W3011328782","https://openalex.org/W3025150890","https://openalex.org/W3144866048","https://openalex.org/W3151056947","https://openalex.org/W3170621707","https://openalex.org/W4200503401","https://openalex.org/W4210546866","https://openalex.org/W4293499849","https://openalex.org/W4308649820","https://openalex.org/W4318039502","https://openalex.org/W4385667068"],"related_works":["https://openalex.org/W3144866048","https://openalex.org/W3025150890","https://openalex.org/W4210546866","https://openalex.org/W4225428317","https://openalex.org/W4293244082","https://openalex.org/W7161598031","https://openalex.org/W6990818216","https://openalex.org/W3013789431","https://openalex.org/W4404246205","https://openalex.org/W3149142491"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2024-05-04T00:00:00"}