{"id":"https://openalex.org/W4396590837","doi":"https://doi.org/10.1158/1538-7445.sabcs23-po1-03-11","title":"Abstract PO1-03-11: Camrelizumab in Combination with Nab-Paclitaxel and Carboplatin versus Nab-Paclitaxel and Carboplatin as Neoadjuvant Therapy for Triple Negative Breast Cancer: A Multicenter, Open-Label, Randomized Controlled Study","display_name":"Abstract PO1-03-11: Camrelizumab in Combination with Nab-Paclitaxel and Carboplatin versus Nab-Paclitaxel and Carboplatin as Neoadjuvant Therapy for Triple Negative Breast Cancer: A Multicenter, Open-Label, Randomized Controlled Study","publication_year":2024,"publication_date":"2024-05-02","ids":{"openalex":"https://openalex.org/W4396590837","doi":"https://doi.org/10.1158/1538-7445.sabcs23-po1-03-11"},"language":"en","primary_location":{"id":"doi:10.1158/1538-7445.sabcs23-po1-03-11","doi":"https://doi.org/10.1158/1538-7445.sabcs23-po1-03-11","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1158/1538-7445.sabcs23-po1-03-11","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065294384","display_name":"Weipeng Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weipeng Zhao","raw_affiliation_strings":["1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;","institution_ids":["https://openalex.org/I2802573037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100327859","display_name":"Xin Wang","orcid":"https://orcid.org/0000-0001-9325-3194","observed_orcids":["https://orcid.org/0000-0001-9325-3194"]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xin Wang","raw_affiliation_strings":["1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;","institution_ids":["https://openalex.org/I2802573037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100392778","display_name":"Bin Zhang","orcid":"https://orcid.org/0000-0001-6834-4705","observed_orcids":["https://orcid.org/0000-0001-6834-4705"]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Zhang","raw_affiliation_strings":["1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;","institution_ids":["https://openalex.org/I2802573037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008310956","display_name":"Yehui Shi","orcid":"https://orcid.org/0000-0001-9649-7119","observed_orcids":["https://orcid.org/0000-0001-9649-7119"]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yehui Shi","raw_affiliation_strings":["1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;","institution_ids":["https://openalex.org/I2802573037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100337500","display_name":"Chen Wang","orcid":"https://orcid.org/0000-0001-7857-5435","observed_orcids":["https://orcid.org/0000-0001-7857-5435","https://orcid.org/0000-0003-2638-3081"]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chen Wang","raw_affiliation_strings":["2Tianjin Medical University Cancer Institute and Hospital;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Tianjin Medical University Cancer Institute and Hospital;","institution_ids":["https://openalex.org/I2802573037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100407879","display_name":"Xu Wang","orcid":"https://orcid.org/0000-0002-5053-3142","observed_orcids":["https://orcid.org/0000-0002-5053-3142"]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xu Wang","raw_affiliation_strings":["1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;","institution_ids":["https://openalex.org/I2802573037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101947774","display_name":"Shufen Li","orcid":"https://orcid.org/0000-0002-7338-2770","observed_orcids":["https://orcid.org/0000-0002-7338-2770"]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shufen Li","raw_affiliation_strings":["2Tianjin Medical University Cancer Institute and Hospital;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Tianjin Medical University Cancer Institute and Hospital;","institution_ids":["https://openalex.org/I2802573037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112570153","display_name":"Chunfang Hao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]},{"id":"https://openalex.org/I5740404","display_name":"Tianjin Medical University","ror":"https://ror.org/02mh8wx89","country_code":"CN","type":"education","lineage":["https://openalex.org/I5740404"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunfang Hao","raw_affiliation_strings":["3Tianjin Medical University Cancer Institute & Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Tianjin Medical University Cancer Institute & Hospital","institution_ids":["https://openalex.org/I2802573037","https://openalex.org/I5740404"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ning Lu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ning Lu","raw_affiliation_strings":["2Tianjin Medical University Cancer Institute and Hospital;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Tianjin Medical University Cancer Institute and Hospital;","institution_ids":["https://openalex.org/I2802573037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100561576","display_name":"Yongsheng Jia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yongsheng Jia","raw_affiliation_strings":["1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;","institution_ids":["https://openalex.org/I2802573037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100425554","display_name":"Li Zhang","orcid":"https://orcid.org/0000-0002-3617-2627","observed_orcids":["https://orcid.org/0000-0002-3617-2627","https://orcid.org/0000-0003-2756-2620","https://orcid.org/0009-0001-8129-4308"]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Zhang","raw_affiliation_strings":["1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;","institution_ids":["https://openalex.org/I2802573037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100322309","display_name":"Lan Zhang","orcid":"https://orcid.org/0000-0002-7572-1035","observed_orcids":["https://orcid.org/0000-0002-7572-1035","https://orcid.org/0009-0005-1074-0736","https://orcid.org/0009-0008-3967-9571"]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lan Zhang","raw_affiliation_strings":["1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;","institution_ids":["https://openalex.org/I2802573037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079793624","display_name":"Weixin Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weixin Sun","raw_affiliation_strings":["1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;","institution_ids":["https://openalex.org/I2802573037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077382421","display_name":"Xuchen Cao","orcid":"https://orcid.org/0000-0003-3216-6673","observed_orcids":["https://orcid.org/0000-0003-3216-6673"]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuchen Cao","raw_affiliation_strings":["2Tianjin Medical University Cancer Institute and Hospital;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Tianjin Medical University Cancer Institute and Hospital;","institution_ids":["https://openalex.org/I2802573037"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091530007","display_name":"Zhongsheng Tong","orcid":"https://orcid.org/0000-0001-8060-5699","observed_orcids":["https://orcid.org/0000-0001-8060-5699","https://orcid.org/0000-0002-6495-3981"]},"institutions":[{"id":"https://openalex.org/I2802573037","display_name":"Tianjin Medical University Cancer Institute and Hospital","ror":"https://ror.org/0152hn881","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802573037"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhongsheng Tong","raw_affiliation_strings":["1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy;","institution_ids":["https://openalex.org/I2802573037"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"84","issue":"9_Supplement","first_page":"PO1","last_page":"03"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/camrelizumab","display_name":"camrelizumab","score":0.9419999718666077},{"id":"https://openalex.org/keywords/triple-negative-breast-cancer","display_name":"triple-negative breast cancer","score":0.8840000033378601},{"id":"https://openalex.org/keywords/neoadjuvant-therapy","display_name":"neoadjuvant therapy","score":0.9869999885559082},{"id":"https://openalex.org/keywords/immune-checkpoint-inhibitors","display_name":"immune checkpoint inhibitors","score":0.6909999847412109},{"id":"https://openalex.org/keywords/anti-pd-1-antibody","display_name":"anti-PD-1","score":0.9179999828338623},{"id":"https://openalex.org/keywords/nab-paclitaxel","display_name":"nab-paclitaxel","score":0.9919999837875366},{"id":"https://openalex.org/keywords/carboplatin","display_name":"carboplatin","score":1.0},{"id":"https://openalex.org/keywords/pathological-complete-response","display_name":"pathological complete response","score":0.8510000109672546},{"id":"https://openalex.org/keywords/early-breast-cancer","display_name":"early breast cancer","score":0.7120000123977661},{"id":"https://openalex.org/keywords/treatment-related-adverse-events","display_name":"treatment-related adverse events","score":0.7799999713897705},{"id":"https://openalex.org/keywords/thrombocytopenia","display_name":"thrombocytopenia","score":0.9290000200271606},{"id":"https://openalex.org/keywords/combination-chemotherapy","display_name":"combination chemotherapy","score":0.41100001335144043},{"id":"https://openalex.org/keywords/residual-cancer-burden","display_name":"residual cancer burden","score":0.6359999775886536},{"id":"https://openalex.org/keywords/event-free-survival","display_name":"event-free survival","score":0.8870000243186951},{"id":"https://openalex.org/keywords/objective-response-rate","display_name":"objective response rate","score":0.6240000128746033}],"concepts":[{"id":"https://openalex.org/C2781451048","wikidata":"https://www.wikidata.org/wiki/Q415588","display_name":"Carboplatin","level":4,"score":0.9199086427688599},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7860879898071289},{"id":"https://openalex.org/C2777292972","wikidata":"https://www.wikidata.org/wiki/Q423762","display_name":"Paclitaxel","level":3,"score":0.7176812887191772},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6177407503128052},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.549988329410553},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5220953226089478},{"id":"https://openalex.org/C2910430875","wikidata":"https://www.wikidata.org/wiki/Q7251413","display_name":"Nab-paclitaxel","level":4,"score":0.518513560295105},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5076249837875366},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.4368472695350647},{"id":"https://openalex.org/C2780110267","wikidata":"https://www.wikidata.org/wiki/Q7843332","display_name":"Triple-negative breast cancer","level":4,"score":0.4169292449951172},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.26066452264785767},{"id":"https://openalex.org/C2778239845","wikidata":"https://www.wikidata.org/wiki/Q412415","display_name":"Cisplatin","level":3,"score":0.09131923317909241}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1538-7445.sabcs23-po1-03-11","doi":"https://doi.org/10.1158/1538-7445.sabcs23-po1-03-11","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1158/1538-7445.sabcs23-po1-03-11","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4387813622","https://openalex.org/W4410815426","https://openalex.org/W4295819127","https://openalex.org/W4379328887","https://openalex.org/W4411292169","https://openalex.org/W7162507327","https://openalex.org/W4412525420","https://openalex.org/W4411286268","https://openalex.org/W4411291712","https://openalex.org/W4399323475"],"abstract_inverted_index":{"Abstract":[0],"Background:":[1],"Triple-negative":[2],"breast":[3,156],"cancer":[4,171],"(TNBC)":[5],"is":[6,178,352],"recognized":[7],"for":[8,51,406],"its":[9],"aggressive":[10],"nature":[11],"and":[12,26,36,97,109,118,174,190,221,279,334,397,401],"unfavorable":[13],"prognosis.":[14],"Immune":[15],"checkpoint":[16],"inhibitors":[17],"have":[18],"demonstrated":[19,336],"promising":[20],"antitumor":[21],"activity":[22],"in":[23,43,74,197,292,302,305,330,354,393],"both":[24],"neoadjuvant":[25,49,80,234,326],"metastatic":[27],"settings.":[28],"This":[29,55,176],"study":[30,61,177,351],"aimed":[31],"to":[32,112,286,300,356],"assess":[33],"the":[34,65,75,103,114,122,131,134,138,144,183,198,209,215,222,231,241,254,325,350,421],"efficacy":[35],"safety":[37,344],"of":[38,67,86,137,203,233,257,288,328,349,420],"camrelizumab,":[39],"an":[40,342],"anti-PD-1":[41],"antibody,":[42],"conjunction":[44],"with":[45,64,92,180,212,322,332,341,395],"chemotherapy":[46],"as":[47,403],"a":[48,337],"treatment":[50,235,303,327],"early-stage":[52],"TNBC.":[53],"Methods:":[54],"two-phase":[56],"prospective,":[57],"multicenter,":[58],"randomized":[59,110],"controlled":[60],"was":[62,143,218,225],"initiated":[63],"enrollment":[66],"previously":[68],"untreated":[69],"stage":[70],"II-III":[71],"TNBC":[72],"patients":[73,106,194,211,321],"first":[76,135,199],"phase.":[77,200],"They":[78],"received":[79],"therapy":[81],"comprising":[82],"six":[83],"3-week":[84],"cycles":[85],"camrelizumab":[87,115,329],"(200":[88],"mg,":[89],"q3w),":[90],"along":[91],"nab-paclitaxel":[93,117,123,333],"(220":[94],"mg/m2,":[95],"q3w)":[96],"carboplatin":[98,119,125,335],"(AUC":[99],"5,":[100],"q3w).":[101],"In":[102,320],"second":[104,347],"phase,":[105],"were":[107,195,206,259,313],"enrolled":[108,196],"1:1":[111],"either":[113],"plus":[116,124],"group":[120],"or":[121,249],"group.":[126],"The":[127,140,228,346],"present":[128],"report":[129],"covers":[130],"data":[132],"from":[133],"phase":[136,348],"study.":[139],"primary":[141],"endpoint":[142],"total":[145,202],"pathological":[146,157],"complete":[147,158],"response":[148,159,164],"(tpCR,":[149],"ypT0/is":[150],"ypN0)":[151],"rate.":[152],"Secondary":[153],"endpoints":[154],"included":[155],"(bpCR,":[160],"ypT0/is)":[161],"rate,":[162],"objective":[163],"rate":[165,217,224,340],"(ORR),":[166],"event-free":[167],"survival":[168],"(EFS),":[169],"residual":[170],"burden":[172],"(RCB),":[173],"safety.":[175],"registered":[179],"ClinicalTrials.gov,":[181],"under":[182],"identifier":[184],"NCT04907344.":[185],"Results:":[186],"Between":[187],"September":[188],"2021":[189],"March":[191],"2023,":[192],"39":[193,242],"A":[201,411],"35":[204],"(89.7%)":[205],"node-positive.":[207],"Among":[208,240],"32":[210],"evaluable":[213],"efficacy,":[214],"tpCR":[216],"59.4%":[219],"(19/32),":[220],"bpCR":[223],"68.8%":[226],"(22/32).":[227],"ORR":[229],"at":[230,237],"end":[232],"stood":[236],"87.2%":[238],"(34/39).":[239],"patients,":[243,295],"11":[244],"(28.2%)":[245],"experienced":[246],"grade":[247],"3":[248],"higher":[250],"treatment-related":[251,310],"adverse":[252,297,311],"events,":[253],"most":[255],"common":[256],"which":[258],"thrombocytopenia":[260],"(6":[261],"[15.4%]),":[262],"leucopenia":[263],"(5":[264,267],"[12.8%]),":[265,268],"neutropenia":[266],"alanine":[269],"aminotransferase":[270,275],"increased":[271,276],"(2":[272],"[5.1%]),":[273],"aspartate":[274],"(1":[277,281],"[2.6%]),":[278],"hypothyroidism":[280],"[2.6%]).":[282],"Adverse":[283],"events":[284,298,312],"leading":[285,299],"discontinuation":[287],"any":[289],"agent":[290],"occurred":[291,304],"5":[293],"(12.8%)":[294],"while":[296],"delay":[301],"7":[306],"(17.9%)":[307],"patients.":[308,318],"Serious":[309],"reported":[314],"by":[315],"4":[316],"(10.4%)":[317],"Conclusions:":[319],"early":[323],"TNBC,":[324],"combination":[331],"high":[338],"pCR":[339],"acceptable":[343],"profile.":[345],"currently":[353],"progress":[355],"validate":[357],"these":[358],"findings.":[359],"Citation":[360],"Format:":[361],"Weipeng":[362],"Zhao,":[363],"Xin":[364],"Wang,":[365,371,373],"Bin":[366],"Zhang,":[367,383,385],"Yehui":[368],"Shi,":[369],"Chen":[370],"Xu":[372],"Shufen":[374],"Li,":[375],"Chunfang":[376],"Hao,":[377],"Ning":[378],"Lu,":[379],"Yongsheng":[380],"Jia,":[381],"Li":[382],"Lan":[384],"Weixin":[386],"Sun,":[387],"Xuchen":[388],"Cao,":[389],"Zhongsheng":[390],"Tong.":[391],"Camrelizumab":[392],"Combination":[394],"Nab-Paclitaxel":[396,400],"Carboplatin":[398,402],"versus":[399],"Neoadjuvant":[404],"Therapy":[405],"Triple":[407],"Negative":[408],"Breast":[409,425],"Cancer:":[410],"Multicenter,":[412],"Open-Label,":[413],"Randomized":[414],"Controlled":[415],"Study":[416],"[abstract].":[417],"In:":[418],"Proceedings":[419],"2023":[422,428],"San":[423,431],"Antonio":[424],"Cancer":[426,437],"Symposium;":[427],"Dec":[429],"5-9;":[430],"Antonio,":[432],"TX.":[433],"Philadelphia":[434],"(PA):":[435],"AACR;":[436],"Res":[438],"2024;84(9":[439],"Suppl):Abstract":[440],"nr":[441],"PO1-03-11.":[442]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2024-05-03T00:00:00"}