{"id":"https://openalex.org/W4396559879","doi":"https://doi.org/10.7759/cureus.59411","title":"Effects of Switching From Another Sodium-Glucose Cotransporter 2 Inhibitor to Tofogliflozin on Nocturia in Patients With Type 2 Diabetes","display_name":"Effects of Switching From Another Sodium-Glucose Cotransporter 2 Inhibitor to Tofogliflozin on Nocturia in Patients With Type 2 Diabetes","publication_year":2024,"publication_date":"2024-04-30","ids":{"openalex":"https://openalex.org/W4396559879","doi":"https://doi.org/10.7759/cureus.59411","pmid":"https://pubmed.ncbi.nlm.nih.gov/38826603","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11139650"},"language":"en","primary_location":{"id":"doi:10.7759/cureus.59411","doi":"https://doi.org/10.7759/cureus.59411","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.59411","pdf_url":null,"source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.7759/cureus.59411","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110358118","display_name":"Saori Inoue","orcid":"https://orcid.org/0009-0003-5913-5997","observed_orcids":["https://orcid.org/0009-0003-5913-5997"]},"institutions":[{"id":"https://openalex.org/I4210123267","display_name":"Meitetsu Hospital","ror":"https://ror.org/021bj7008","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210123267"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Saori Inoue","raw_affiliation_strings":["Internal Medicine, Meitetsu Hospital, Nagoya, JPN",". Internal Medicine, Kakehashi Tonyobyo Kojyosen Clinic, Nagoya, JPN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine, Meitetsu Hospital, Nagoya, JPN","institution_ids":["https://openalex.org/I4210123267"]},{"raw_affiliation_string":". Internal Medicine, Kakehashi Tonyobyo Kojyosen Clinic, Nagoya, JPN","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111717814","display_name":"Hiroko Yasuda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210123267","display_name":"Meitetsu Hospital","ror":"https://ror.org/021bj7008","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210123267"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroko Yasuda","raw_affiliation_strings":["Internal Medicine, Meitetsu Hospital, Nagoya, JPN",". Internal Medicine, Kakehashi Tonyobyo Kojyosen Clinic, Nagoya, JPN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine, Meitetsu Hospital, Nagoya, JPN","institution_ids":["https://openalex.org/I4210123267"]},{"raw_affiliation_string":". Internal Medicine, Kakehashi Tonyobyo Kojyosen Clinic, Nagoya, JPN","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057501676","display_name":"Kaoru Yoshida","orcid":"https://orcid.org/0000-0001-9805-2818","observed_orcids":["https://orcid.org/0000-0001-9805-2818"]},"institutions":[{"id":"https://openalex.org/I4210123267","display_name":"Meitetsu Hospital","ror":"https://ror.org/021bj7008","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210123267"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kaoru Yoshida","raw_affiliation_strings":["Internal Medicine, Meitetsu Hospital, Nagoya, JPN",". Internal Medicine, Kakehashi Tonyobyo Kojyosen Clinic, Nagoya, JPN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine, Meitetsu Hospital, Nagoya, JPN","institution_ids":["https://openalex.org/I4210123267"]},{"raw_affiliation_string":". Internal Medicine, Kakehashi Tonyobyo Kojyosen Clinic, Nagoya, JPN","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110766051","display_name":"Kazuaki Mori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210123267","display_name":"Meitetsu Hospital","ror":"https://ror.org/021bj7008","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210123267"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuaki Mori","raw_affiliation_strings":["Internal Medicine, Meitetsu Hospital, Nagoya, JPN",". Internal Medicine, Kakehashi Tonyobyo Kojyosen Clinic, Nagoya, JPN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine, Meitetsu Hospital, Nagoya, JPN","institution_ids":["https://openalex.org/I4210123267"]},{"raw_affiliation_string":". Internal Medicine, Kakehashi Tonyobyo Kojyosen Clinic, Nagoya, JPN","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111782471","display_name":"Koichiro Ogawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210123267","display_name":"Meitetsu Hospital","ror":"https://ror.org/021bj7008","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210123267"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Koichiro Ogawa","raw_affiliation_strings":["Internal Medicine, Meitetsu Hospital, Nagoya, JPN",". Internal Medicine, Kakehashi Tonyobyo Kojyosen Clinic, Nagoya, JPN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine, Meitetsu Hospital, Nagoya, JPN","institution_ids":["https://openalex.org/I4210123267"]},{"raw_affiliation_string":". Internal Medicine, Kakehashi Tonyobyo Kojyosen Clinic, Nagoya, JPN","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093200617","display_name":"Yoko Yokotsuka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210123267","display_name":"Meitetsu Hospital","ror":"https://ror.org/021bj7008","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210123267"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoko Yokotsuka","raw_affiliation_strings":["Internal Medicine, Kakehashi Tonyobyo Kojyosen Clinic, Nagoya, JPN",". Internal Medicine, Meitetsu Hospital, Nagoya, JPN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine, Kakehashi Tonyobyo Kojyosen Clinic, Nagoya, JPN","institution_ids":[]},{"raw_affiliation_string":". Internal Medicine, Meitetsu Hospital, Nagoya, JPN","institution_ids":["https://openalex.org/I4210123267"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101739495","display_name":"Hideki Okamoto","orcid":"https://orcid.org/0000-0002-7551-8694","observed_orcids":["https://orcid.org/0000-0002-7551-8694"]},"institutions":[{"id":"https://openalex.org/I4210123267","display_name":"Meitetsu Hospital","ror":"https://ror.org/021bj7008","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210123267"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideki Okamoto","raw_affiliation_strings":["Internal Medicine, Meitetsu Hospital, Nagoya, JPN",". Internal Medicine, Kakehashi Tonyobyo Kojyosen Clinic, Nagoya, JPN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine, Meitetsu Hospital, Nagoya, JPN","institution_ids":["https://openalex.org/I4210123267"]},{"raw_affiliation_string":". Internal Medicine, Kakehashi Tonyobyo Kojyosen Clinic, Nagoya, JPN","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5110358118"],"corresponding_institution_ids":["https://openalex.org/I4210123267"],"apc_list":null,"apc_paid":null,"fwci":1.1058,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.76953899,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"16","issue":"4","first_page":"e59411","last_page":"e59411"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.9580000042915344,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.9580000042915344,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":0.03269999846816063,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tofogliflozin","display_name":"tofogliflozin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/sglt2-inhibitors","display_name":"SGLT2 inhibitors","score":0.9340000152587891},{"id":"https://openalex.org/keywords/drug-switching","display_name":"drug switching","score":0.6729999780654907},{"id":"https://openalex.org/keywords/nocturia","display_name":"nocturia","score":0.8859999775886536},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9900000095367432},{"id":"https://openalex.org/keywords/sleep-quality","display_name":"sleep quality","score":0.9129999876022339},{"id":"https://openalex.org/keywords/water-intake","display_name":"water intake","score":0.7710000276565552},{"id":"https://openalex.org/keywords/empagliflozin","display_name":"empagliflozin","score":0.8500000238418579},{"id":"https://openalex.org/keywords/dapagliflozin","display_name":"dapagliflozin","score":0.9929999709129333},{"id":"https://openalex.org/keywords/canagliflozin","display_name":"canagliflozin","score":0.9440000057220459},{"id":"https://openalex.org/keywords/luseogliflozin","display_name":"luseogliflozin","score":0.9909999966621399},{"id":"https://openalex.org/keywords/ipragliflozin","display_name":"ipragliflozin","score":0.9900000095367432},{"id":"https://openalex.org/keywords/japanese-patients","display_name":"Japanese patients","score":0.4749999940395355}],"concepts":[{"id":"https://openalex.org/C2777333188","wikidata":"https://www.wikidata.org/wiki/Q1426443","display_name":"Nocturia","level":3,"score":0.7586303949356079},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.7389973402023315},{"id":"https://openalex.org/C2777422806","wikidata":"https://www.wikidata.org/wiki/Q409898","display_name":"Dapagliflozin","level":4,"score":0.7143550515174866},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4575241804122925},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.43921077251434326},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.43742847442626953},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.43034467101097107},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3317105770111084},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.12555259466171265}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.7759/cureus.59411","doi":"https://doi.org/10.7759/cureus.59411","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.59411","pdf_url":null,"source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11139650","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11139650","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11139650/pdf/cureus-0016-00000059411.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Text"},{"id":"pmid:38826603","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38826603","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.7759/cureus.59411","doi":"https://doi.org/10.7759/cureus.59411","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.59411","pdf_url":null,"source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4396559879.pdf","grobid_xml":"https://content.openalex.org/works/W4396559879.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W2063497842","https://openalex.org/W2140411181","https://openalex.org/W2146264128","https://openalex.org/W2159917561","https://openalex.org/W2166304122","https://openalex.org/W2211127675","https://openalex.org/W2301210108","https://openalex.org/W2423399057","https://openalex.org/W2594555601","https://openalex.org/W2606681868","https://openalex.org/W2750269437","https://openalex.org/W2939222610","https://openalex.org/W2954203217","https://openalex.org/W2999945678","https://openalex.org/W3039967840","https://openalex.org/W3092753640","https://openalex.org/W4291283522"],"related_works":["https://openalex.org/W4402602075","https://openalex.org/W4408251439","https://openalex.org/W4399690056","https://openalex.org/W4311784803","https://openalex.org/W4412728760","https://openalex.org/W4415681153","https://openalex.org/W4402593849","https://openalex.org/W4411094599","https://openalex.org/W2339487668","https://openalex.org/W3092753640"],"abstract_inverted_index":{"Objective:":[0],"We":[1,124],"aimed":[2,34],"to":[3,17,35,72,87,157,191,234],"characterize":[4],"the":[5,37,40,91,96,98,104,109,120,126,131,135,150,182,208,238,252],"effects":[6],"of":[7,42,51,56,93,100,106,108,119,130,184,207,240,254,256],"a":[8,21,70,178,248],"switch":[9,71,229],"from":[10,187,212,230],"another":[11,231],"sodium-glucose":[12],"cotransporter":[13],"2":[14,29,260],"(SGLT2)":[15],"inhibitor":[16,233],"tofogliflozin,":[18],"which":[19],"has":[20],"shorter":[22],"half-life,":[23],"in":[24,39,90,181,205,224],"Japanese":[25],"patients":[26,58,257],"with":[27,258],"type":[28,259],"diabetes.":[30,261],"In":[31,82],"particular,":[32],"we":[33],"assess":[36],"changes":[38,89,204],"frequency":[41,92,183,239],"nocturnal":[43,185,241],"urination":[44,94],"and":[45,103,141,172],"other":[46,64,209],"parameters":[47,79,211],"after":[48],"four":[49,75],"months":[50],"treatment.":[52],"Methods:":[53],"A":[54],"cohort":[55],"31":[57],"who":[59],"were":[60,80,85,122,159,201],"taking":[61],"SGLT2":[62,147,232],"inhibitors":[63,148],"than":[65],"tofogliflozin":[66,158,235],"was":[67,177],"selected":[68],"for":[69,117],"tofogliflozin.":[73],"After":[74],"months,":[76],"their":[77],"clinical":[78],"assessed.":[81],"addition,":[83],"questionnaires":[84],"administered":[86],"evaluate":[88],"during":[95],"day,":[97],"amount":[99],"water":[101],"intake,":[102],"quality":[105,253],"sleep":[107,225],"participants":[110,121,151,221],"at":[111],"this":[112],"time":[113],"point.":[114],"Results:":[115],"Data":[116],"30":[118],"analyzed.":[123],"documented":[125],"following":[127],"comorbid":[128],"conditions":[129],"urinary":[132],"system":[133],"among":[134],"participants:":[136],"prostatic":[137],"hypertrophy":[138],"(4,":[139,164],"13%)":[140],"prostate":[142],"cancer":[143],"(1,":[144,170,174],"3.3%).":[145,175],"The":[146,214,228],"that":[149,218,244],"had":[152],"been":[153],"using":[154],"before":[155],"switching":[156],"empagliflozin":[160],"(16,":[161],"53%),":[162],"dapagliflozin":[163],"13%),":[165],"canagliflozin":[166],"(8,":[167],"27%),":[168],"luseogliflozin":[169],"3.3%),":[171],"ipragliflozin":[173],"There":[176],"significant":[179,203],"decrease":[180],"urination,":[186,242],"2.6":[188],"\u00b1":[189,193],"0.83":[190],"2.1":[192],"1.3":[194],"times":[195],"(P":[196],"=":[197],"0.014).":[198],"However,":[199],"there":[200],"no":[202],"any":[206],"measured":[210],"baseline.":[213],"questionnaire":[215],"survey":[216],"showed":[217],"10":[219],"(33%)":[220],"experienced":[222],"improvements":[223],"quality.":[226],"Conclusions:":[227],"may":[236,246],"reduce":[237],"implying":[243],"it":[245],"have":[247],"positive":[249],"impact":[250],"on":[251],"life":[255]},"counts_by_year":[{"year":2025,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-05-02T00:00:00"}