{"id":"https://openalex.org/W4396558342","doi":"https://doi.org/10.1038/s41372-024-01982-8","title":"Feasibility of intranasal human milk as stem cell therapy in preterm infants with intraventricular hemorrhage","display_name":"Feasibility of intranasal human milk as stem cell therapy in preterm infants with intraventricular hemorrhage","publication_year":2024,"publication_date":"2024-04-30","ids":{"openalex":"https://openalex.org/W4396558342","doi":"https://doi.org/10.1038/s41372-024-01982-8","pmid":"https://pubmed.ncbi.nlm.nih.gov/38688998"},"language":"en","primary_location":{"id":"doi:10.1038/s41372-024-01982-8","doi":"https://doi.org/10.1038/s41372-024-01982-8","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41372-024-01982-8","pdf_url":null,"source":{"id":"https://openalex.org/S18455948","display_name":"Journal of Perinatology","issn_l":"0743-8346","issn":["0743-8346","1476-5543"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Perinatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018711184","display_name":"Rebecca A. Hoban","orcid":"https://orcid.org/0000-0001-9457-8791","observed_orcids":["https://orcid.org/0000-0001-9457-8791"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I2801317318","display_name":"Hospital for Sick Children","ror":"https://ror.org/057q4rt57","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801317318"]}],"countries":["CA","US"],"is_corresponding":true,"raw_author_name":"Rebecca Hoban","raw_affiliation_strings":["Division of Neonatology, The Hospital for Sick Children/University of Toronto, Toronto, ON, Canada. rebecca.hoban@seattlechildrens.org","Division of Neonatology, University of Washington, Seattle, WA, USA. rebecca.hoban@seattlechildrens.org","Division of Neonatology, The Hospital for Sick Children/University of Toronto, Toronto, ON, Canada"],"raw_orcid":"https://orcid.org/0000-0001-9457-8791","affiliations":[{"raw_affiliation_string":"Division of Neonatology, The Hospital for Sick Children/University of Toronto, Toronto, ON, Canada. rebecca.hoban@seattlechildrens.org","institution_ids":["https://openalex.org/I185261750","https://openalex.org/I2801317318"]},{"raw_affiliation_string":"Division of Neonatology, University of Washington, Seattle, WA, USA. rebecca.hoban@seattlechildrens.org","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Division of Neonatology, The Hospital for Sick Children/University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750","https://openalex.org/I2801317318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034272141","display_name":"Alessia Gallipoli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2801317318","display_name":"Hospital for Sick Children","ror":"https://ror.org/057q4rt57","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801317318"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Alessia Gallipoli","raw_affiliation_strings":["Division of Neonatology, The Hospital for Sick Children/University of Toronto, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Neonatology, The Hospital for Sick Children/University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750","https://openalex.org/I2801317318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059031931","display_name":"Marisa Signorile","orcid":"https://orcid.org/0000-0001-5310-1903","observed_orcids":["https://orcid.org/0000-0001-5310-1903"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Marisa Signorile","raw_affiliation_strings":["Ted Rogers Computational Program, Peter Munk Cardiac Centre, University Health Network, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ted Rogers Computational Program, Peter Munk Cardiac Centre, University Health Network, Toronto, ON, Canada","institution_ids":["https://openalex.org/I1325899441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024962280","display_name":"Poonam Mander","orcid":"https://orcid.org/0009-0003-7533-4179","observed_orcids":["https://orcid.org/0009-0003-7533-4179"]},"institutions":[{"id":"https://openalex.org/I4210157932","display_name":"CReATe Fertility Centre","ror":"https://ror.org/047acnh17","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210157932"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Poonam Mander","raw_affiliation_strings":["CReATe Fertility Centre, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CReATe Fertility Centre, Toronto, ON, Canada","institution_ids":["https://openalex.org/I4210157932"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025483610","display_name":"Andr\u00e9e Gauthier-Fisher","orcid":"https://orcid.org/0000-0002-1932-4684","observed_orcids":["https://orcid.org/0000-0002-1932-4684"]},"institutions":[{"id":"https://openalex.org/I4210157932","display_name":"CReATe Fertility Centre","ror":"https://ror.org/047acnh17","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210157932"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Andree Gauthier-Fisher","raw_affiliation_strings":["CReATe Fertility Centre, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CReATe Fertility Centre, Toronto, ON, Canada","institution_ids":["https://openalex.org/I4210157932"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005426292","display_name":"Clifford Lawrence Librach","orcid":"https://orcid.org/0000-0002-9699-4059","observed_orcids":["https://orcid.org/0000-0002-9699-4059"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I4210157932","display_name":"CReATe Fertility Centre","ror":"https://ror.org/047acnh17","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210157932"]},{"id":"https://openalex.org/I4210167439","display_name":"Sunnybrook Hospital","ror":"https://ror.org/008kn1a71","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1323843004","https://openalex.org/I4210167439"]},{"id":"https://openalex.org/I4391768120","display_name":"Sunnybrook Research Institute","ror":"https://ror.org/05n0tzs53","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1323843004","https://openalex.org/I185261750","https://openalex.org/I4391768120"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Clifford Librach","raw_affiliation_strings":["CReATe Fertility Centre, Toronto, ON, Canada","Department of Obstetrics and Gynecology, IMS and Physiology, University of Toronto, Toronto, ON, Canada","Sunnybrook Research Institute, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CReATe Fertility Centre, Toronto, ON, Canada","institution_ids":["https://openalex.org/I4210157932"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, IMS and Physiology, University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Sunnybrook Research Institute, Toronto, ON, Canada","institution_ids":["https://openalex.org/I4210167439","https://openalex.org/I4391768120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113894814","display_name":"Diane Wilson","orcid":"https://orcid.org/0000-0001-8350-5706","observed_orcids":["https://orcid.org/0000-0001-8350-5706"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2801317318","display_name":"Hospital for Sick Children","ror":"https://ror.org/057q4rt57","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801317318"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Diane Wilson","raw_affiliation_strings":["Division of Neonatology, The Hospital for Sick Children/University of Toronto, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Neonatology, The Hospital for Sick Children/University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750","https://openalex.org/I2801317318"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011104635","display_name":"Sharon L. Unger","orcid":"https://orcid.org/0000-0001-8091-5742","observed_orcids":["https://orcid.org/0000-0001-8091-5742"]},"institutions":[{"id":"https://openalex.org/I2800394539","display_name":"Izaak Walton Killam Health Centre","ror":"https://ror.org/0064zg438","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2800394539"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Sharon Unger","raw_affiliation_strings":["Department of Paediatrics, Izaak Walton Killam Hospital, Halifax, NS, Canada"],"raw_orcid":"https://orcid.org/0000-0001-8091-5742","affiliations":[{"raw_affiliation_string":"Department of Paediatrics, Izaak Walton Killam Hospital, Halifax, NS, Canada","institution_ids":["https://openalex.org/I2800394539"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5018711184"],"corresponding_institution_ids":["https://openalex.org/I185261750","https://openalex.org/I201448701","https://openalex.org/I2801317318"],"apc_list":{"value":4590,"currency":"USD","value_usd":4590},"apc_paid":null,"fwci":8.9244,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.98548032,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"44","issue":"11","first_page":"1652","last_page":"1657"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.9365000128746033,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.9365000128746033,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11294","display_name":"Infant Nutrition and Health","score":0.0215000007301569,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11060","display_name":"Infant Development and Preterm Care","score":0.01510000042617321,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intraventricular-hemorrhage","display_name":"intraventricular hemorrhage","score":0.9739999771118164},{"id":"https://openalex.org/keywords/preterm-infants","display_name":"preterm infants","score":0.9559999704360962},{"id":"https://openalex.org/keywords/stem-cell-therapy","display_name":"stem cell therapy","score":0.7509999871253967},{"id":"https://openalex.org/keywords/pluripotent-stem-cells","display_name":"pluripotent stem cells","score":0.8040000200271606},{"id":"https://openalex.org/keywords/neonatal-brain-injury","display_name":"neonatal brain injury","score":0.8009999990463257},{"id":"https://openalex.org/keywords/blood-brain-barrier-permeability","display_name":"blood-brain barrier permeability","score":0.8659999966621399},{"id":"https://openalex.org/keywords/feasibility","display_name":"feasibility","score":0.5120000243186951},{"id":"https://openalex.org/keywords/adverse-effects","display_name":"adverse effects","score":0.5550000071525574},{"id":"https://openalex.org/keywords/provider-acceptability","display_name":"provider acceptability","score":0.8299999833106995}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9746201038360596},{"id":"https://openalex.org/C2779252433","wikidata":"https://www.wikidata.org/wiki/Q6058597","display_name":"Intraventricular hemorrhage","level":4,"score":0.8620221614837646},{"id":"https://openalex.org/C85663871","wikidata":"https://www.wikidata.org/wiki/Q6966562","display_name":"Nasal administration","level":2,"score":0.7075179815292358},{"id":"https://openalex.org/C536800656","wikidata":"https://www.wikidata.org/wiki/Q898674","display_name":"Neonatology","level":3,"score":0.5196055769920349},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.47554704546928406},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.4277946949005127},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.33250975608825684},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3286435008049011},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.2834831774234772},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1719057261943817},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000074042","descriptor_name":"Cerebral Intraventricular Hemorrhage","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D000281","descriptor_name":"Administration, Intranasal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002543","descriptor_name":"Cerebral Hemorrhage","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D005240","descriptor_name":"Feasibility Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007235","descriptor_name":"Infant, Premature, Diseases","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D007363","descriptor_name":"Intensive Care Units, Neonatal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008895","descriptor_name":"Milk, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D033581","descriptor_name":"Stem Cell Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/s41372-024-01982-8","doi":"https://doi.org/10.1038/s41372-024-01982-8","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41372-024-01982-8","pdf_url":null,"source":{"id":"https://openalex.org/S18455948","display_name":"Journal of Perinatology","issn_l":"0743-8346","issn":["0743-8346","1476-5543"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Perinatology","raw_type":"journal-article"},{"id":"pmid:38688998","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38688998","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of perinatology : official journal of the California Perinatal Association","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W204171329","https://openalex.org/W1988987474","https://openalex.org/W2029130632","https://openalex.org/W2045608491","https://openalex.org/W2046224781","https://openalex.org/W2091423694","https://openalex.org/W2099196117","https://openalex.org/W2166360485","https://openalex.org/W2239467861","https://openalex.org/W2267514764","https://openalex.org/W2531568882","https://openalex.org/W2592679361","https://openalex.org/W2613986718","https://openalex.org/W2761963498","https://openalex.org/W2891433611","https://openalex.org/W2898778617","https://openalex.org/W2902397304","https://openalex.org/W2983559674","https://openalex.org/W3166127339","https://openalex.org/W3200665931","https://openalex.org/W4226391763","https://openalex.org/W4386463163"],"related_works":["https://openalex.org/W4403277682","https://openalex.org/W2898778617","https://openalex.org/W7170403067","https://openalex.org/W4414832885","https://openalex.org/W2888109284","https://openalex.org/W4408305747","https://openalex.org/W2904991971","https://openalex.org/W4320856590","https://openalex.org/W7161645724","https://openalex.org/W7220779478"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-05-02T00:00:00"}