{"id":"https://openalex.org/W4396543322","doi":"https://doi.org/10.1158/1078-0432.25728629","title":"Supplementary Figure S2 from Radiotherapy Enhances Metastasis Through Immune Suppression by Inducing PD-L1 and MDSC in Distal Sites","display_name":"Supplementary Figure S2 from Radiotherapy Enhances Metastasis Through Immune Suppression by Inducing PD-L1 and MDSC in Distal Sites","publication_year":2024,"publication_date":"2024-05-01","ids":{"openalex":"https://openalex.org/W4396543322","doi":"https://doi.org/10.1158/1078-0432.25728629"},"language":"en","primary_location":{"id":"doi:10.1158/1078-0432.25728629","doi":"https://doi.org/10.1158/1078-0432.25728629","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.25728629","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1078-0432.25728629","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010111727","display_name":"Yuzhu Hou","orcid":"https://orcid.org/0000-0001-8274-027X","observed_orcids":["https://orcid.org/0000-0001-8274-027X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yuzhu Hou","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8274-027X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047294733","display_name":"Kaiting Yang","orcid":"https://orcid.org/0000-0001-9328-5655","observed_orcids":["https://orcid.org/0000-0001-9328-5655"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kaiting Yang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9328-5655","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100462044","display_name":"Liangliang Wang","orcid":"https://orcid.org/0000-0001-8340-5190","observed_orcids":["https://orcid.org/0000-0001-8340-5190"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Liangliang Wang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8340-5190","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089105425","display_name":"Jiaai Wang","orcid":"https://orcid.org/0000-0003-3217-7444","observed_orcids":["https://orcid.org/0000-0003-3217-7444"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jiaai Wang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3217-7444","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004564183","display_name":"Xiaona Huang","orcid":"https://orcid.org/0000-0002-9983-5723","observed_orcids":["https://orcid.org/0000-0002-9983-5723"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiaona Huang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9983-5723","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030054574","display_name":"Andr\u00e1s Piffk\u00f3","orcid":"https://orcid.org/0000-0001-5300-6594","observed_orcids":["https://orcid.org/0000-0001-5300-6594"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andr\u00e1s Piffk\u00f3","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5300-6594","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022120806","display_name":"Sean Z. Luo","orcid":"https://orcid.org/0009-0006-8652-8827","observed_orcids":["https://orcid.org/0009-0006-8652-8827"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sean Z. Luo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0006-8652-8827","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061014817","display_name":"Xinshuang Yu","orcid":"https://orcid.org/0000-0001-9095-3435","observed_orcids":["https://orcid.org/0000-0001-9095-3435"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xinshuang Yu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9095-3435","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012963546","display_name":"Enyu Rao","orcid":"https://orcid.org/0000-0003-2949-2902","observed_orcids":["https://orcid.org/0000-0003-2949-2902"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Enyu Rao","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2949-2902","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002479296","display_name":"Carlos N. Martinez","orcid":"https://orcid.org/0000-0002-6934-9847","observed_orcids":["https://orcid.org/0000-0002-6934-9847"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carlos Martinez","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6934-9847","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044918446","display_name":"Jason Bugno","orcid":"https://orcid.org/0000-0002-3046-8072","observed_orcids":["https://orcid.org/0000-0002-3046-8072"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jason Bugno","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3046-8072","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085709802","display_name":"Matthias Mack","orcid":"https://orcid.org/0000-0002-3157-7262","observed_orcids":["https://orcid.org/0000-0002-3157-7262"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matthias Mack","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3157-7262","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063904421","display_name":"Everett E. Vokes","orcid":"https://orcid.org/0000-0002-8645-8068","observed_orcids":["https://orcid.org/0000-0002-8645-8068"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Everett E. Vokes","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8645-8068","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030967817","display_name":"Sean P. Pitroda","orcid":"https://orcid.org/0000-0003-3056-7991","observed_orcids":["https://orcid.org/0000-0003-3056-7991"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sean P. Pitroda","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3056-7991","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055476105","display_name":"Steven J. Chmura","orcid":"https://orcid.org/0000-0001-8851-7108","observed_orcids":["https://orcid.org/0000-0001-8851-7108"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Steven J. Chmura","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8851-7108","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054855052","display_name":"Ralph R. Weichselbaum","orcid":"https://orcid.org/0000-0002-5643-8939","observed_orcids":["https://orcid.org/0000-0002-5643-8939"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ralph R. Weichselbaum","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5643-8939","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5102854287","display_name":"Hua Laura Liang","orcid":"https://orcid.org/0000-0001-5512-8595","observed_orcids":["https://orcid.org/0000-0001-5512-8595"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hua Laura Liang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5512-8595","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9663000106811523,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9663000106811523,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.023900000378489494,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12626","display_name":"Cancer, Stress, Anesthesia, and Immune Response","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.9760000109672546},{"id":"https://openalex.org/keywords/lung-metastasis","display_name":"lung metastasis","score":0.8259999752044678},{"id":"https://openalex.org/keywords/pd-l1","display_name":"PD-L1","score":0.8579999804496765},{"id":"https://openalex.org/keywords/tumor-associated-macrophages","display_name":"tumor-associated macrophages","score":0.8080000281333923},{"id":"https://openalex.org/keywords/myeloid-derived-suppressor-cells","display_name":"myeloid-derived suppressor cells","score":0.8640000224113464},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.890999972820282},{"id":"https://openalex.org/keywords/leukocyte-migration","display_name":"leukocyte migration","score":0.9070000052452087},{"id":"https://openalex.org/keywords/gene-expression-pathways","display_name":"gene expression pathways","score":0.8820000290870667},{"id":"https://openalex.org/keywords/irradiated-mice","display_name":"irradiated mice","score":0.7179999947547913}],"concepts":[{"id":"https://openalex.org/C2781053074","wikidata":"https://www.wikidata.org/wiki/Q21100639","display_name":"PD-L1","level":4,"score":0.5439924001693726},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5377232432365417},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.43201589584350586},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.43151846528053284},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.29860740900039673},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25957536697387695},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.2565721571445465},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2009454071521759}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1158/1078-0432.25728629","doi":"https://doi.org/10.1158/1078-0432.25728629","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.25728629","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/1078-0432.25728629.v1","doi":"https://doi.org/10.1158/1078-0432.25728629.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.25728629.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/25728629","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Figure_S2_from_Radiotherapy_Enhances_Metastasis_Through_Immune_Suppression_by_Inducing_PD-L1_and_MDSC_in_Distal_Sites/25728629","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1078-0432.25728629","doi":"https://doi.org/10.1158/1078-0432.25728629","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.25728629","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4392388168","https://openalex.org/W4396543458","https://openalex.org/W2029507224","https://openalex.org/W2052727153","https://openalex.org/W2444354051","https://openalex.org/W6920890236","https://openalex.org/W4308385779","https://openalex.org/W4309738718","https://openalex.org/W2529896352","https://openalex.org/W7208285054"],"abstract_inverted_index":{"Supplementary":[0],"figure":[1],"2.":[2],"Gene":[3],"expression":[4],"pathways":[5],"are":[6],"enriched":[7],"for":[8],"PD-L1":[9],"production":[10],"and":[11],"leukocyte":[12],"migration":[13],"in":[14],"lung":[15],"of":[16],"irradiated":[17],"mice.":[18]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-05-02T00:00:00"}