{"id":"https://openalex.org/W4396508649","doi":"https://doi.org/10.1016/j.trre.2024.100857","title":"Recurrent complement-mediated Hemolytic uremic syndrome after kidney transplantation","display_name":"Recurrent complement-mediated Hemolytic uremic syndrome after kidney transplantation","publication_year":2024,"publication_date":"2024-04-30","ids":{"openalex":"https://openalex.org/W4396508649","doi":"https://doi.org/10.1016/j.trre.2024.100857","pmid":"https://pubmed.ncbi.nlm.nih.gov/38749097"},"language":"en","primary_location":{"id":"doi:10.1016/j.trre.2024.100857","doi":"https://doi.org/10.1016/j.trre.2024.100857","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.trre.2024.100857","pdf_url":null,"source":{"id":"https://openalex.org/S188185022","display_name":"Transplantation Reviews","issn_l":"0955-470X","issn":["0955-470X","1557-9816"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation Reviews","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065839571","display_name":"Shota Obata","orcid":"https://orcid.org/0000-0002-7609-0757","observed_orcids":["https://orcid.org/0000-0002-7609-0757"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shota Obata","raw_affiliation_strings":["Precision Immunology Institute, Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Precision Immunology Institute, Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090121244","display_name":"Frank E. Hullekes","orcid":"https://orcid.org/0000-0002-2260-7175","observed_orcids":["https://orcid.org/0000-0002-2260-7175"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frank Hullekes","raw_affiliation_strings":["Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083826351","display_name":"Leonardo V. Riella","orcid":"https://orcid.org/0000-0002-7636-3196","observed_orcids":["https://orcid.org/0000-0002-7636-3196"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leonardo V. Riella","raw_affiliation_strings":["Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America; Department of Medicine, Nephrology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America","Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America","Department of Medicine, Nephrology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America; Department of Medicine, Nephrology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Medicine, Nephrology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005075162","display_name":"Paolo Cravedi","orcid":"https://orcid.org/0000-0001-7837-0923","observed_orcids":["https://orcid.org/0000-0001-7837-0923"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Paolo Cravedi","raw_affiliation_strings":["Precision Immunology Institute, Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America. Electronic address: paolo.cravedi@mssm.edu","Precision Immunology Institute, Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Precision Immunology Institute, Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America. Electronic address: paolo.cravedi@mssm.edu","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Precision Immunology Institute, Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America","institution_ids":["https://openalex.org/I98704320"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5005075162"],"corresponding_institution_ids":["https://openalex.org/I98704320"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":null,"fwci":0.3078,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.30209281,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"38","issue":"3","first_page":"100857","last_page":"100857"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atypical-hemolytic-uremic-syndrome","display_name":"atypical hemolytic uremic syndrome","score":0.9160000085830688},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.9409999847412109},{"id":"https://openalex.org/keywords/recurrence","display_name":"recurrence","score":0.5090000033378601},{"id":"https://openalex.org/keywords/eculizumab","display_name":"eculizumab","score":0.8399999737739563},{"id":"https://openalex.org/keywords/alternative-complement-pathway","display_name":"alternative complement pathway","score":0.8569999933242798},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.7409999966621399},{"id":"https://openalex.org/keywords/graft-loss","display_name":"graft loss","score":0.8059999942779541}],"concepts":[{"id":"https://openalex.org/C2777991916","wikidata":"https://www.wikidata.org/wiki/Q421617","display_name":"Eculizumab","level":4,"score":0.9424306750297546},{"id":"https://openalex.org/C2777637130","wikidata":"https://www.wikidata.org/wiki/Q17165460","display_name":"Atypical hemolytic uremic syndrome","level":4,"score":0.9124265313148499},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8079214692115784},{"id":"https://openalex.org/C111684460","wikidata":"https://www.wikidata.org/wiki/Q334848","display_name":"Complement system","level":3,"score":0.6972090005874634},{"id":"https://openalex.org/C2778715236","wikidata":"https://www.wikidata.org/wiki/Q55622662","display_name":"Discontinuation","level":2,"score":0.6189225912094116},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.5366617441177368},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5278439521789551},{"id":"https://openalex.org/C112313634","wikidata":"https://www.wikidata.org/wiki/Q7886648","display_name":"Complement (music)","level":5,"score":0.5052409768104553},{"id":"https://openalex.org/C2780303639","wikidata":"https://www.wikidata.org/wiki/Q740909","display_name":"Kidney transplantation","level":3,"score":0.5010416507720947},{"id":"https://openalex.org/C71318922","wikidata":"https://www.wikidata.org/wiki/Q426181","display_name":"Complement component 5","level":4,"score":0.47489017248153687},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.32549208402633667},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.27736330032348633},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.22521904110908508},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22349637746810913},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10290485620498657},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09827995300292969},{"id":"https://openalex.org/C188082640","wikidata":"https://www.wikidata.org/wiki/Q1780899","display_name":"Complementation","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D006463","descriptor_name":"Hemolytic-Uremic Syndrome","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D051056","descriptor_name":"Complement Inactivating Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D061067","descriptor_name":"Antibodies, Monoclonal, Humanized","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.trre.2024.100857","doi":"https://doi.org/10.1016/j.trre.2024.100857","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.trre.2024.100857","pdf_url":null,"source":{"id":"https://openalex.org/S188185022","display_name":"Transplantation Reviews","issn_l":"0955-470X","issn":["0955-470X","1557-9816"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation Reviews","raw_type":"journal-article"},{"id":"pmid:38749097","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38749097","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation reviews (Orlando, Fla.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":98,"referenced_works":["https://openalex.org/W343272032","https://openalex.org/W1486365785","https://openalex.org/W1507314459","https://openalex.org/W1970432269","https://openalex.org/W1976386747","https://openalex.org/W1980117859","https://openalex.org/W1997303422","https://openalex.org/W1998953261","https://openalex.org/W1999827339","https://openalex.org/W2008607429","https://openalex.org/W2012403186","https://openalex.org/W2012630248","https://openalex.org/W2014513484","https://openalex.org/W2014850360","https://openalex.org/W2024541829","https://openalex.org/W2032912400","https://openalex.org/W2035128042","https://openalex.org/W2048117130","https://openalex.org/W2052693906","https://openalex.org/W2056054199","https://openalex.org/W2057649456","https://openalex.org/W2078820067","https://openalex.org/W2079142360","https://openalex.org/W2088133018","https://openalex.org/W2089013072","https://openalex.org/W2094308013","https://openalex.org/W2097173937","https://openalex.org/W2106578061","https://openalex.org/W2106675927","https://openalex.org/W2118510193","https://openalex.org/W2124841845","https://openalex.org/W2125750727","https://openalex.org/W2130956616","https://openalex.org/W2143431905","https://openalex.org/W2149943632","https://openalex.org/W2152506674","https://openalex.org/W2158153997","https://openalex.org/W2164205336","https://openalex.org/W2166637331","https://openalex.org/W2171275709","https://openalex.org/W2187945026","https://openalex.org/W2264090971","https://openalex.org/W2305176160","https://openalex.org/W2317925853","https://openalex.org/W2396758747","https://openalex.org/W2540481111","https://openalex.org/W2553923194","https://openalex.org/W2565152113","https://openalex.org/W2577385521","https://openalex.org/W2590258299","https://openalex.org/W2593388942","https://openalex.org/W2604565584","https://openalex.org/W2607363181","https://openalex.org/W2727335336","https://openalex.org/W2746096526","https://openalex.org/W2751882444","https://openalex.org/W2765296883","https://openalex.org/W2767069795","https://openalex.org/W2785967297","https://openalex.org/W2789927285","https://openalex.org/W2807740363","https://openalex.org/W2886517507","https://openalex.org/W2902241490","https://openalex.org/W2921983598","https://openalex.org/W2923386909","https://openalex.org/W2943893614","https://openalex.org/W2947520624","https://openalex.org/W2955977081","https://openalex.org/W2978175710","https://openalex.org/W3009429865","https://openalex.org/W3017097384","https://openalex.org/W3027010094","https://openalex.org/W3028752638","https://openalex.org/W3049762768","https://openalex.org/W3071414872","https://openalex.org/W3096041971","https://openalex.org/W3108107578","https://openalex.org/W3111584343","https://openalex.org/W3122718279","https://openalex.org/W3136005316","https://openalex.org/W3157401890","https://openalex.org/W3177013745","https://openalex.org/W3199180046","https://openalex.org/W3212793120","https://openalex.org/W4205632884","https://openalex.org/W4210409062","https://openalex.org/W4229373824","https://openalex.org/W4230935285","https://openalex.org/W4238378618","https://openalex.org/W4242833177","https://openalex.org/W4283312476","https://openalex.org/W4292850278","https://openalex.org/W4306688623","https://openalex.org/W4306824865","https://openalex.org/W4309660097","https://openalex.org/W4320000557","https://openalex.org/W4385707806","https://openalex.org/W6611564507"],"related_works":["https://openalex.org/W3035728254","https://openalex.org/W2768116123","https://openalex.org/W1963776691","https://openalex.org/W4402461013","https://openalex.org/W1987485716","https://openalex.org/W1998953261","https://openalex.org/W3207186825","https://openalex.org/W2011115907","https://openalex.org/W2606306308","https://openalex.org/W1999827339"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-05-01T00:00:00"}
