{"id":"https://openalex.org/W4396502170","doi":"https://doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a4989","title":"Latent Class Analyses of the CLOVERS Trial Reveal Novel Phenotypes of Sepsis Patients With Shock Presenting to the Emergency Department","display_name":"Latent Class Analyses of the CLOVERS Trial Reveal Novel Phenotypes of Sepsis Patients With Shock Presenting to the Emergency Department","publication_year":2024,"publication_date":"2024-04-30","ids":{"openalex":"https://openalex.org/W4396502170","doi":"https://doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a4989"},"language":"en","primary_location":{"id":"doi:10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a4989","doi":"https://doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a4989","is_oa":false,"landing_page_url":"https://doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a4989","pdf_url":null,"source":{"id":"https://openalex.org/S93356601","display_name":"American Journal of Respiratory and Critical Care Medicine","issn_l":"1073-449X","issn":["1073-449X","1535-4970"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"C16. SEPSIS IN 2024: FROM BENCH TO BEDSIDE AND AROUND THE WORLD","raw_type":"proceedings-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086111114","display_name":"Elizabeth A. Gay","orcid":"https://orcid.org/0000-0002-7151-5082","observed_orcids":["https://orcid.org/0000-0002-7151-5082"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E.A. Gay","raw_affiliation_strings":["Department of Internal Medicine, Massachusetts General Hospital, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Massachusetts General Hospital, Boston, MA, United States","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":null,"display_name":"B. Bartek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B. Bartek","raw_affiliation_strings":["Department of Anesthesiology, Washington University, St. Louis, MO, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Washington University, St. Louis, MO, United States","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":null,"display_name":"H. Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Lee","raw_affiliation_strings":["Biostatistics Center, Mass General Research Institute, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biostatistics Center, Mass General Research Institute, Boston, MA, United States","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078445016","display_name":"Eric P. Schmidt","orcid":"https://orcid.org/0000-0002-7360-0504","observed_orcids":["https://orcid.org/0000-0002-7360-0504"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E.P. Schmidt","raw_affiliation_strings":["Division of Pulmonary Sciences and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pulmonary Sciences and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, United States","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039748898","display_name":"Nathan Ivan Shapiro","orcid":"https://orcid.org/0000-0003-3508-4390","observed_orcids":["https://orcid.org/0000-0003-3508-4390"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"N. Shapiro","raw_affiliation_strings":["Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States","institution_ids":["https://openalex.org/I1316535847"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006201777","display_name":"Bruce Thompson","orcid":"https://orcid.org/0000-0001-6391-0448","observed_orcids":["https://orcid.org/0000-0001-6391-0448","https://orcid.org/0000-0002-5885-0652"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B.T. Thompson","raw_affiliation_strings":["Division of Pulmonary Sciences and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pulmonary Sciences and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, United States","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052576862","display_name":"Michael A. Matthay","orcid":"https://orcid.org/0000-0003-3039-8155","observed_orcids":["https://orcid.org/0000-0003-3039-8155"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M.A. Matthay","raw_affiliation_strings":["Departments of Medicine and Anesthesia, Univ of California At San Francisco, San Francisco, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Anesthesia, Univ of California At San Francisco, San Francisco, CA, United States","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062212651","display_name":"Carolyn S. Calfee","orcid":"https://orcid.org/0000-0001-9208-6865","observed_orcids":["https://orcid.org/0000-0001-9208-6865"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C.S. Calfee","raw_affiliation_strings":["Departments of Medicine and Anesthesia, Univ of California At San Francisco, San Francisco, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Anesthesia, Univ of California At San Francisco, San Francisco, CA, United States","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051494461","display_name":"Pratik Sinha","orcid":"https://orcid.org/0000-0003-3751-9079","observed_orcids":["https://orcid.org/0000-0003-3751-9079"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Sinha","raw_affiliation_strings":["Department of Anesthesiology, Washington University, St. Louis, MO, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Washington University, St. Louis, MO, United States","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"A4989","last_page":"A4989"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11095","display_name":"Emergency and Acute Care Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.9760000109672546},{"id":"https://openalex.org/keywords/septic-shock","display_name":"septic shock","score":0.9020000100135803},{"id":"https://openalex.org/keywords/latent-class-analysis","display_name":"latent class analysis","score":0.7289999723434448},{"id":"https://openalex.org/keywords/clinical-phenotype","display_name":"clinical phenotype","score":0.8270000219345093},{"id":"https://openalex.org/keywords/emergency-department","display_name":"emergency department","score":0.7829999923706055},{"id":"https://openalex.org/keywords/sepsis-subtypes","display_name":"sepsis subtypes","score":0.6039999723434448}],"concepts":[{"id":"https://openalex.org/C2780724011","wikidata":"https://www.wikidata.org/wiki/Q1295316","display_name":"Emergency department","level":2,"score":0.7654447555541992},{"id":"https://openalex.org/C2781300812","wikidata":"https://www.wikidata.org/wiki/Q178061","display_name":"Shock (circulatory)","level":2,"score":0.6449345350265503},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.6130752563476562},{"id":"https://openalex.org/C2777628635","wikidata":"https://www.wikidata.org/wiki/Q1765564","display_name":"Septic shock","level":3,"score":0.5217219591140747},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5011727809906006},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3980446755886078},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23158621788024902},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.19502779841423035},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19400280714035034},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09309634566307068},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0706486701965332},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a4989","doi":"https://doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a4989","is_oa":false,"landing_page_url":"https://doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a4989","pdf_url":null,"source":{"id":"https://openalex.org/S93356601","display_name":"American Journal of Respiratory and Critical Care Medicine","issn_l":"1073-449X","issn":["1073-449X","1535-4970"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"C16. SEPSIS IN 2024: FROM BENCH TO BEDSIDE AND AROUND THE WORLD","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8360999822616577,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2806376027","https://openalex.org/W4225311916","https://openalex.org/W4396504353","https://openalex.org/W4210317135","https://openalex.org/W4280647936","https://openalex.org/W4396516307","https://openalex.org/W7138856037","https://openalex.org/W3041623652","https://openalex.org/W4389385661","https://openalex.org/W4389729975"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2024-05-01T00:00:00"}