{"id":"https://openalex.org/W4395037274","doi":"https://doi.org/10.1161/circ.138.suppl_1.16981","title":"Abstract 16981: Prevalence of Primary Severe Hypertriglyceridemia in Olmsted County, Minnesota: A Community-Based Study","display_name":"Abstract 16981: Prevalence of Primary Severe Hypertriglyceridemia in Olmsted County, Minnesota: A Community-Based Study","publication_year":2018,"publication_date":"2018-11-06","ids":{"openalex":"https://openalex.org/W4395037274","doi":"https://doi.org/10.1161/circ.138.suppl_1.16981"},"language":"en","primary_location":{"id":"doi:10.1161/circ.138.suppl_1.16981","doi":"https://doi.org/10.1161/circ.138.suppl_1.16981","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1161/circ.138.suppl_1.16981","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036634053","display_name":"Harigopal Sandhyavenu","orcid":"https://orcid.org/0000-0002-2567-6651","observed_orcids":["https://orcid.org/0000-0002-2567-6651"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harigopal Sandhyavenu","raw_affiliation_strings":["Cardiovascular department, Mayo Clinic, Rochester, MN","Harigopal Sandhyavenu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular department, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Harigopal Sandhyavenu","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070767104","display_name":"Ahmed Khurshid Pasha","orcid":"https://orcid.org/0000-0001-9257-640X","observed_orcids":["https://orcid.org/0000-0001-9257-640X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ahmed Pasha","raw_affiliation_strings":["Cardiovascular department, Mayo Clinic, Rochester, MN","Ahmed Pasha"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular department, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Ahmed Pasha","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005621109","display_name":"Medhat Farwati","orcid":"https://orcid.org/0000-0002-9052-9690","observed_orcids":["https://orcid.org/0000-0002-9052-9690"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Medhat Farwati","raw_affiliation_strings":["Cardiovascular department, Mayo Clinic, Rochester, MN","Medhat Farwati"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular department, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Medhat Farwati","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037957960","display_name":"Kent R. Bailey","orcid":"https://orcid.org/0000-0001-8968-643X","observed_orcids":["https://orcid.org/0000-0001-8968-643X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kent Bailey","raw_affiliation_strings":["Dept of Health Sciences Rsch, Mayo Clinic, Rochester, MN","Kent Bailey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept of Health Sciences Rsch, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Kent Bailey","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065025844","display_name":"Iftikhar J. Kullo","orcid":"https://orcid.org/0000-0002-6524-3471","observed_orcids":["https://orcid.org/0000-0002-6524-3471"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Iftikhar Kullo","raw_affiliation_strings":["Cardiovascular department, Mayo Clinic, Rochester, MN","Iftikhar Kullo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular department, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Iftikhar Kullo","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"138","issue":"Suppl_1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.008299999870359898,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prevalence","display_name":"prevalence","score":0.6309999823570251},{"id":"https://openalex.org/keywords/triglyceride-levels","display_name":"triglyceride levels","score":0.625},{"id":"https://openalex.org/keywords/mixed-dyslipidemia","display_name":"mixed dyslipidemia","score":0.8939999938011169},{"id":"https://openalex.org/keywords/secondary-hypertriglyceridemia","display_name":"secondary hypertriglyceridemia","score":0.9739999771118164},{"id":"https://openalex.org/keywords/lipid-lowering-therapy","display_name":"lipid-lowering therapy","score":0.972000002861023},{"id":"https://openalex.org/keywords/rochester-epidemiology-project","display_name":"Rochester Epidemiology Project","score":0.8080000281333923},{"id":"https://openalex.org/keywords/olmsted-county-minnesota","display_name":"Olmsted County, Minnesota","score":0.9710000157356262},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.7459999918937683},{"id":"https://openalex.org/keywords/rochester-minnesota","display_name":"Rochester, Minnesota","score":0.7509999871253967},{"id":"https://openalex.org/keywords/minnesota","display_name":"Minnesota","score":0.6389999985694885},{"id":"https://openalex.org/keywords/rochester","display_name":"Rochester","score":0.8489999771118164}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9578217267990112},{"id":"https://openalex.org/C2776919658","wikidata":"https://www.wikidata.org/wiki/Q1467339","display_name":"Hypertriglyceridemia","level":4,"score":0.7688636779785156},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.5479075312614441},{"id":"https://openalex.org/C2778525166","wikidata":"https://www.wikidata.org/wiki/Q7353974","display_name":"Rochester Epidemiology Project","level":4,"score":0.441249281167984},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.30007895827293396},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2915618419647217},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.07121726870536804},{"id":"https://openalex.org/C3018709324","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Population based study","level":3,"score":0.0},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1161/circ.138.suppl_1.16981","doi":"https://doi.org/10.1161/circ.138.suppl_1.16981","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1161/circ.138.suppl_1.16981","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4386571011","https://openalex.org/W3110926563","https://openalex.org/W4385832042","https://openalex.org/W2904076154","https://openalex.org/W2906605519","https://openalex.org/W4376601421","https://openalex.org/W4413367057","https://openalex.org/W2627090023","https://openalex.org/W2127059895","https://openalex.org/W4386247814"],"abstract_inverted_index":{"Introduction:":[0],"Severe":[1],"hypertriglyceridemia":[2],"(SHTG),":[3],"defined":[4,84,116,146],"as":[5,85,117,147],"plasma":[6],"triglyceride":[7],"(TG)":[8],"level":[9],"\u2265":[10,76],"500":[11,77],"mg/dl,":[12],"is":[13,42,265],"a":[14,46,182,229],"risk":[15],"factor":[16],"for":[17,185,201],"cardiovascular":[18],"disease.":[19],"In":[20],"the":[21,27,34,40,51,63,86,94,120,156,163,188,195,204,224,234,273],"NHANES":[22],"dataset":[23],"(2001":[24],"-":[25],"2006),":[26],"prevalence":[28,35,52,205,274],"of":[29,36,53,89,122,149,155,174,199,206,210,216,223,231,248,275],"SHTG":[30,38,158,168,186,207,212,218,226,252,264],"was":[31,83,115,145,169,208,213,219],"1.7%.":[32],"However,":[33],"primary":[37,54,157,192,217,225,251,263],"in":[39,56,119,171,233,255,269],"community":[41],"unknown.":[43],"We":[44,61,97],"conducted":[45],"community-based":[47],"study":[48,95],"to":[49,71,272],"estimate":[50],"SHTG,":[55],"Olmsted":[57,202],"County,":[58,203],"Minnesota.":[59],"Methods:":[60],"used":[62],"Rochester":[64],"Epidemiology":[65],"Project":[66],"(REP)":[67],"records":[68],"linkage":[69],"system":[70],"identify":[72],"individuals":[73,99,159,173,249],"with":[74,100,250],"TG":[75,90],"mg/dl":[78,92,105],"between":[79],"1998-2015.":[80],"Index":[81],"date":[82],"first":[87],"documentation":[88],"\u2265500":[91,104],"during":[93],"period.":[96],"excluded":[98],"mixed":[101,178],"hyperlipidemia":[102],"(TG":[103],"and":[106,137,187,215,238,279],"non-high":[107],"density":[108],"lipoprotein":[109],"(HDL)":[110],"cholesterol":[111],"\u2265190":[112],"mg/dl).":[113],"HTG":[114,144],"secondary":[118,152,183,211],"presence":[121],"hypothyroidism,":[123],"biliary":[124],"obstruction,":[125],"nephrotic":[126],"syndrome,":[127],"uncontrolled":[128],"diabetes,":[129],"pregnancy,":[130],"liver":[131],"disease,":[132],"renal":[133],"failure,":[134],"BMI":[135],"\u226535":[136],"medication":[138],"use":[139],"(isotretinoin,":[140],"tetracyclines,":[141],"anti-retrovirals).":[142],"Primary":[143],"absence":[148],"an":[150],"identifiable":[151],"etiology.":[153],"Characteristics":[154,247],"were":[160,240],"ascertained":[161],"from":[162],"electronic":[164,235],"health":[165,236],"record.":[166],"Results:":[167],"identified":[170],"3802":[172],"whom":[175],"2511":[176],"had":[177,181,191,228],"hyperlipidemia,":[179],"743":[180],"cause":[184],"remaining":[189],"548":[190],"SHTG.":[193],"Using":[194],"2015":[196],"population":[197],"census":[198],"151,436":[200],"2.5%,":[209],"0.49%":[214],"0.36%.":[220],"Only":[221],"half":[222],"group":[227],"diagnosis":[230],"dyslipidemia":[232],"record":[237],"44.3%":[239],"on":[241,244],"lipid-lowering":[242],"therapy":[243],"index":[245],"date.":[246],"are":[253],"summarized":[254],"Table":[256],"1.":[257],"Conclusions:":[258],"These":[259],"data":[260],"highlight":[261],"that":[262],"relatively":[266],"common":[267],"(\u22481":[268],"300,":[270],"similar":[271],"familial":[276],"hypercholesterolemia),":[277],"underdiagnosed":[278],"undertreated.":[280]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2024-04-24T00:00:00"}