{"id":"https://openalex.org/W4394996258","doi":"https://doi.org/10.1186/s13036-024-00424-5","title":"Engineering water exchange is a safe and effective method for magnetic resonance imaging in diverse cell types","display_name":"Engineering water exchange is a safe and effective method for magnetic resonance imaging in diverse cell types","publication_year":2024,"publication_date":"2024-04-22","ids":{"openalex":"https://openalex.org/W4394996258","doi":"https://doi.org/10.1186/s13036-024-00424-5","pmid":"https://pubmed.ncbi.nlm.nih.gov/37986852","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10659288"},"language":"en","primary_location":{"id":"doi:10.1186/s13036-024-00424-5","doi":"https://doi.org/10.1186/s13036-024-00424-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13036-024-00424-5","pdf_url":"https://jbioleng.biomedcentral.com/counter/pdf/10.1186/s13036-024-00424-5","source":{"id":"https://openalex.org/S156566788","display_name":"Journal of Biological Engineering","issn_l":"1754-1611","issn":["1754-1611"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Engineering","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://jbioleng.biomedcentral.com/counter/pdf/10.1186/s13036-024-00424-5","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043304120","display_name":"Austin D.C. Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Austin D.C. Miller","raw_affiliation_strings":["Biomolecular Science and Engineering Graduate Program, University of California, Santa Barbara, CA 93106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomolecular Science and Engineering Graduate Program, University of California, Santa Barbara, CA 93106, USA","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103135062","display_name":"Soham P. Chowdhury","orcid":"https://orcid.org/0009-0008-8321-8406","observed_orcids":["https://orcid.org/0009-0008-8321-8406"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Soham P. Chowdhury","raw_affiliation_strings":["Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hadley W. Hanson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hadley W. Hanson","raw_affiliation_strings":["Biomolecular Science and Engineering Graduate Program, University of California, Santa Barbara, CA 93106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomolecular Science and Engineering Graduate Program, University of California, Santa Barbara, CA 93106, USA","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093251271","display_name":"Sarah K. Linderman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah K. Linderman","raw_affiliation_strings":["Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010622074","display_name":"Hannah I. Ghasemi","orcid":"https://orcid.org/0000-0002-5795-7271","observed_orcids":["https://orcid.org/0000-0002-5795-7271"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hannah I. Ghasemi","raw_affiliation_strings":["Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043309241","display_name":"Wyatt D. Miller","orcid":"https://orcid.org/0000-0002-6152-8533","observed_orcids":["https://orcid.org/0000-0002-6152-8533"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wyatt D. Miller","raw_affiliation_strings":["Biomolecular Science and Engineering Graduate Program, University of California, Santa Barbara, CA 93106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomolecular Science and Engineering Graduate Program, University of California, Santa Barbara, CA 93106, USA","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049281520","display_name":"Meghan A. Morrissey","orcid":"https://orcid.org/0000-0002-0531-4864","observed_orcids":["https://orcid.org/0000-0002-0531-4864"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Meghan A. Morrissey","raw_affiliation_strings":["Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA"],"raw_orcid":"https://orcid.org/0000-0002-0531-4864","affiliations":[{"raw_affiliation_string":"Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002966076","display_name":"Chris D. Richardson","orcid":"https://orcid.org/0000-0003-3122-4851","observed_orcids":["https://orcid.org/0000-0003-3122-4851"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chris D. Richardson","raw_affiliation_strings":["Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA"],"raw_orcid":"https://orcid.org/0000-0003-3122-4851","affiliations":[{"raw_affiliation_string":"Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007386757","display_name":"Brooke M. Gardner","orcid":"https://orcid.org/0000-0001-7999-8827","observed_orcids":["https://orcid.org/0000-0001-7999-8827"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brooke M. Gardner","raw_affiliation_strings":["Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA"],"raw_orcid":"https://orcid.org/0000-0001-7999-8827","affiliations":[{"raw_affiliation_string":"Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063875629","display_name":"Arnab Mukherjee","orcid":"https://orcid.org/0000-0003-3571-8015","observed_orcids":["https://orcid.org/0000-0003-3571-8015"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Arnab Mukherjee","raw_affiliation_strings":["Biomolecular Science and Engineering Graduate Program, University of California, Santa Barbara, CA 93106, USA","Department of Bioengineering, University of California, Santa Barbara, CA 93106, USA","Department of Chemical Engineering, University of California, Santa Barbara, CA 93106, USA","Department of Chemistry, University of California, Santa Barbara, CA 93106, USA","Neuroscience Research Institute, University of California, Santa Barbara, CA 93106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomolecular Science and Engineering Graduate Program, University of California, Santa Barbara, CA 93106, USA","institution_ids":["https://openalex.org/I154570441"]},{"raw_affiliation_string":"Department of Bioengineering, University of California, Santa Barbara, CA 93106, USA","institution_ids":["https://openalex.org/I154570441"]},{"raw_affiliation_string":"Department of Chemical Engineering, University of California, Santa Barbara, CA 93106, USA","institution_ids":["https://openalex.org/I154570441"]},{"raw_affiliation_string":"Department of Chemistry, University of California, Santa Barbara, CA 93106, USA","institution_ids":["https://openalex.org/I154570441"]},{"raw_affiliation_string":"Neuroscience Research Institute, University of California, Santa Barbara, CA 93106, USA","institution_ids":["https://openalex.org/I154570441"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5063875629"],"corresponding_institution_ids":["https://openalex.org/I154570441"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":0.7784,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.64049804,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"18","issue":"1","first_page":"30","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.3366999924182892,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.3366999924182892,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12603","display_name":"NMR spectroscopy and applications","score":0.3034999966621399,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.15870000422000885,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aquaporin-1","display_name":"aquaporin-1","score":0.996999979019165},{"id":"https://openalex.org/keywords/aquaporins","display_name":"aquaporins","score":0.3799999952316284},{"id":"https://openalex.org/keywords/endoplasmic-reticulum-stress","display_name":"endoplasmic reticulum stress","score":0.9430000185966492},{"id":"https://openalex.org/keywords/phagocytosis","display_name":"phagocytosis","score":0.7950000166893005},{"id":"https://openalex.org/keywords/insulin-secretion","display_name":"insulin secretion","score":0.8569999933242798},{"id":"https://openalex.org/keywords/tumor-cell-migration","display_name":"tumor cell migration","score":0.9819999933242798},{"id":"https://openalex.org/keywords/in-vivo-imaging","display_name":"in vivo imaging","score":0.6110000014305115},{"id":"https://openalex.org/keywords/cell-viability","display_name":"cell viability","score":0.5109999775886536}],"concepts":[{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6678118705749512},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6155623197555542},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.5187654495239258},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.459716796875},{"id":"https://openalex.org/C154280991","wikidata":"https://www.wikidata.org/wiki/Q623090","display_name":"Aquaporin","level":2,"score":0.44582900404930115},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.41667264699935913},{"id":"https://openalex.org/C53227056","wikidata":"https://www.wikidata.org/wiki/Q189152","display_name":"Viability assay","level":3,"score":0.41004714369773865},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40202248096466064},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3654232919216156},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3599510192871094},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.2351442277431488},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14633247256278992},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10383915901184082}],"mesh":[],"locations_count":8,"locations":[{"id":"doi:10.1186/s13036-024-00424-5","doi":"https://doi.org/10.1186/s13036-024-00424-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13036-024-00424-5","pdf_url":"https://jbioleng.biomedcentral.com/counter/pdf/10.1186/s13036-024-00424-5","source":{"id":"https://openalex.org/S156566788","display_name":"Journal of Biological Engineering","issn_l":"1754-1611","issn":["1754-1611"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Engineering","raw_type":"journal-article"},{"id":"doi:10.1101/2023.11.07.566095","doi":"https://doi.org/10.1101/2023.11.07.566095","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2023.11.07.566095","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2023/11/10/2023.11.07.566095.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:11035135","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11035135","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11035135/pdf/13036_2024_Article_424.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Biol Eng","raw_type":"Text"},{"id":"pmid:37986852","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37986852","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"bioRxiv : the preprint server for biology","raw_type":"Preprint"},{"id":"pmid:38649904","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38649904","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biological engineering","raw_type":"Journal Article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt0zc3c9ps","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/0zc3c9ps","pdf_url":"https://escholarship.org/content/qt0zc3c9ps/qt0zc3c9ps.pdf?t=sdbw5a","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Biological Engineering, vol 18, iss 1","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10659288","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10659288","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10659288/pdf/nihpp-2023.11.07.566095v1.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:b290fa163a9e4789a667fe3c07ab057a","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b290fa163a9e4789a667fe3c07ab057a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-14 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s13036-024-00424-5","doi":"https://doi.org/10.1186/s13036-024-00424-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13036-024-00424-5","pdf_url":"https://jbioleng.biomedcentral.com/counter/pdf/10.1186/s13036-024-00424-5","source":{"id":"https://openalex.org/S156566788","display_name":"Journal of Biological Engineering","issn_l":"1754-1611","issn":["1754-1611"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Engineering","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"study_designs":[],"awards":[{"id":"https://openalex.org/G321649331","display_name":null,"funder_award_id":"W911NF-19-D-0001-0009","funder_id":"https://openalex.org/F4320338502","funder_display_name":"Institute for Collaborative Biotechnologies"},{"id":"https://openalex.org/G4096929283","display_name":"A genetically encoded MRI reporter for noninvasive imaging of activity-dependent gene expression in neurons","funder_award_id":"R03DA050971","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G5008113308","display_name":null,"funder_award_id":"C23CR5592","funder_id":"https://openalex.org/F4320315321","funder_display_name":"Cancer Research Coordinating Committee"},{"id":"https://openalex.org/G6912258823","display_name":"Materials Research Science and Engineering Center at UCSB","funder_award_id":"1720256","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7962055198","display_name":"Investigating the role of AAA+-ATPases in peroxisome biology","funder_award_id":"R00GM121880","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G8729722292","display_name":"Engineering fluorescence and magnetic resonance reporter genes for imaging biological function in hypoxic cells and in vivo","funder_award_id":"R35GM133530","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000869092","display_name":"Metal-free, genetically encoded reporters for calcium recording with MRI","funder_award_id":"R01NS128278","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G9000894296","display_name":"Signal Integration during Phagocytosis","funder_award_id":"R35GM146935","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000905370","display_name":"Defining DNA resection and protein localization changes that occur during DSB repair","funder_award_id":"R35GM142975","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306147","display_name":"Brain and Behavior Research Foundation","ror":"https://ror.org/03a63f080"},{"id":"https://openalex.org/F4320314849","display_name":"Searle Scholars Program","ror":null},{"id":"https://openalex.org/F4320315321","display_name":"Cancer Research Coordinating Committee","ror":null},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332500","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320338281","display_name":"Army Research Office","ror":"https://ror.org/05epdh915"},{"id":"https://openalex.org/F4320338502","display_name":"Institute for Collaborative Biotechnologies","ror":"https://ror.org/04kz4p343"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4394996258.pdf","grobid_xml":"https://content.openalex.org/works/W4394996258.grobid-xml"},"referenced_works_count":77,"referenced_works":["https://openalex.org/W1450867862","https://openalex.org/W1507864482","https://openalex.org/W1592495560","https://openalex.org/W1605077957","https://openalex.org/W1697178647","https://openalex.org/W1874831549","https://openalex.org/W1970672280","https://openalex.org/W1974923926","https://openalex.org/W1983159179","https://openalex.org/W1987824410","https://openalex.org/W1991919920","https://openalex.org/W1995844056","https://openalex.org/W2000494473","https://openalex.org/W2002628032","https://openalex.org/W2003581319","https://openalex.org/W2006224145","https://openalex.org/W2010789559","https://openalex.org/W2018912704","https://openalex.org/W2029054052","https://openalex.org/W2032417358","https://openalex.org/W2033567679","https://openalex.org/W2040915777","https://openalex.org/W2041178795","https://openalex.org/W2063616884","https://openalex.org/W2065555928","https://openalex.org/W2067203318","https://openalex.org/W2080601632","https://openalex.org/W2083877042","https://openalex.org/W2084761689","https://openalex.org/W2099331667","https://openalex.org/W2107277218","https://openalex.org/W2108250239","https://openalex.org/W2112048948","https://openalex.org/W2114360920","https://openalex.org/W2130970481","https://openalex.org/W2145132757","https://openalex.org/W2153074213","https://openalex.org/W2160857316","https://openalex.org/W2160978749","https://openalex.org/W2201881805","https://openalex.org/W2290792317","https://openalex.org/W2296900205","https://openalex.org/W2331195764","https://openalex.org/W2338871610","https://openalex.org/W2407094878","https://openalex.org/W2488203923","https://openalex.org/W2500691849","https://openalex.org/W2524204594","https://openalex.org/W2560333870","https://openalex.org/W2561217468","https://openalex.org/W2611210276","https://openalex.org/W2621155715","https://openalex.org/W2782137090","https://openalex.org/W2790600737","https://openalex.org/W2811301994","https://openalex.org/W2892479404","https://openalex.org/W2898690501","https://openalex.org/W2949407488","https://openalex.org/W2949483171","https://openalex.org/W2951446739","https://openalex.org/W2975580645","https://openalex.org/W2987582022","https://openalex.org/W3003581486","https://openalex.org/W3036982869","https://openalex.org/W3128058096","https://openalex.org/W3192339688","https://openalex.org/W3196897371","https://openalex.org/W4206655776","https://openalex.org/W4210408537","https://openalex.org/W4220891075","https://openalex.org/W4225016307","https://openalex.org/W4283159240","https://openalex.org/W4289443637","https://openalex.org/W4290612745","https://openalex.org/W4310785350","https://openalex.org/W4313454866","https://openalex.org/W4353041361"],"related_works":["https://openalex.org/W7084177696","https://openalex.org/W2561217468","https://openalex.org/W4379377811","https://openalex.org/W7020728845","https://openalex.org/W4391172199","https://openalex.org/W4400768531","https://openalex.org/W4392463514","https://openalex.org/W4387344737","https://openalex.org/W2469325110","https://openalex.org/W7146196814"],"abstract_inverted_index":{"Aquaporin-1":[0],"(Aqp1),":[1],"a":[2,60,160,170],"water":[3,35],"channel,":[4],"has":[5],"garnered":[6],"significant":[7],"interest":[8],"for":[9,173],"cell-based":[10],"medicine":[11],"and":[12,47,91,135,163],"in":[13,37,84,139,174],"vivo":[14,175],"synthetic":[15],"biology":[16],"due":[17],"to":[18,21,25,148],"its":[19,56,166],"ability":[20],"be":[22],"genetically":[23],"encoded":[24],"produce":[26],"magnetic":[27,74],"resonance":[28,75],"signals":[29,76],"by":[30],"increasing":[31],"the":[32,42,140,155],"rate":[33],"of":[34,44,111,157],"diffusion":[36],"cells.":[38],"However,":[39],"concerns":[40,153],"regarding":[41,154],"effects":[43,123],"Aqp1":[45,70,97,118,158],"overexpression":[46,98],"increased":[48],"membrane":[49,112],"diffusivity":[50],"on":[51,124],"cell":[52,80,86,137,142],"physiology":[53],"have":[54],"limited":[55],"widespread":[57],"use":[58],"as":[59,129,159,169],"deep-tissue":[61],"reporter.":[62],"In":[63],"this":[64],"study,":[65],"we":[66,115],"present":[67],"evidence":[68],"that":[69,96,117],"generates":[71],"strong":[72],"diffusion-based":[73],"without":[77],"adversely":[78],"affecting":[79],"viability":[81],"or":[82],"morphology":[83],"diverse":[85],"lines":[87],"derived":[88],"from":[89],"mice":[90],"humans.":[92],"Our":[93],"findings":[94,145],"indicate":[95],"does":[99],"not":[100],"induce":[101],"ER":[102],"stress,":[103],"which":[104],"is":[105],"frequently":[106],"associated":[107],"with":[108],"heterologous":[109],"expression":[110,119],"proteins.":[113],"Furthermore,":[114],"observed":[116],"had":[120],"no":[121],"detrimental":[122],"native":[125],"biological":[126],"activities,":[127],"such":[128],"phagocytosis,":[130],"immune":[131],"response,":[132],"insulin":[133],"secretion,":[134],"tumor":[136],"migration":[138],"analyzed":[141],"lines.":[143],"These":[144],"should":[146,164],"serve":[147],"alleviate":[149],"any":[150],"lingering":[151],"safety":[152],"utilization":[156],"genetic":[161],"reporter":[162,172],"foster":[165],"broader":[167],"application":[168],"noninvasive":[171],"studies.":[176]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2024-04-23T00:00:00"}