{"id":"https://openalex.org/W4394979542","doi":"https://doi.org/10.1093/sleep/zsae067.0868","title":"0868 Cardiac Remodeling: Apnea-Hypopnea Index as a Predictor for Changes in Left Atrial Volume","display_name":"0868 Cardiac Remodeling: Apnea-Hypopnea Index as a Predictor for Changes in Left Atrial Volume","publication_year":2024,"publication_date":"2024-04-20","ids":{"openalex":"https://openalex.org/W4394979542","doi":"https://doi.org/10.1093/sleep/zsae067.0868"},"language":"en","primary_location":{"id":"doi:10.1093/sleep/zsae067.0868","doi":"https://doi.org/10.1093/sleep/zsae067.0868","is_oa":true,"landing_page_url":"https://doi.org/10.1093/sleep/zsae067.0868","pdf_url":"https://academic.oup.com/sleep/article-pdf/47/Supplement_1/A372/57290516/zsae067.0868.pdf","source":{"id":"https://openalex.org/S42921845","display_name":"SLEEP","issn_l":"0161-8105","issn":["0161-8105","1550-9109"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SLEEP","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/sleep/article-pdf/47/Supplement_1/A372/57290516/zsae067.0868.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Steve Chung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steve Chung","raw_affiliation_strings":["University of Michigan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Michigan","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5095789777","display_name":"Sussan Kokinda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sussan Kokinda","raw_affiliation_strings":["University of Michigan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Michigan","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050954561","display_name":"Andy Nguyen-Phan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andy Nguyen-Phan","raw_affiliation_strings":["University of Michigan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Michigan","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091584382","display_name":"Ronald David Chervin","orcid":"https://orcid.org/0000-0002-8227-5133","observed_orcids":["https://orcid.org/0000-0002-8227-5133"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronald Chervin","raw_affiliation_strings":["University of Michigan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Michigan","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045917207","display_name":"Sonja G. Sch\u00fctz","orcid":"https://orcid.org/0000-0002-0918-9714","observed_orcids":["https://orcid.org/0000-0002-0918-9714"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sonja Schuetz","raw_affiliation_strings":["University of Michigan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Michigan","institution_ids":["https://openalex.org/I27837315"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I27837315"],"apc_list":{"value":4607,"currency":"USD","value_usd":4607},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.07025568,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"47","issue":"Supplement_1","first_page":"A372","last_page":"A373"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiac-remodeling","display_name":"cardiac remodeling","score":0.6909999847412109},{"id":"https://openalex.org/keywords/left-atrial-volume","display_name":"left atrial volume","score":0.9049999713897705},{"id":"https://openalex.org/keywords/apnea-hypopnea-index","display_name":"apnea-hypopnea index","score":0.9459999799728394},{"id":"https://openalex.org/keywords/sleep-disordered-breathing","display_name":"sleep-disordered breathing","score":0.9760000109672546},{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"obstructive sleep apnea","score":0.9959999918937683},{"id":"https://openalex.org/keywords/left-atrial-size","display_name":"left atrial size","score":0.8989999890327454},{"id":"https://openalex.org/keywords/arrhythmia-risk","display_name":"arrhythmia risk","score":0.7699999809265137},{"id":"https://openalex.org/keywords/sleep-apnea-severity","display_name":"sleep apnea severity","score":0.6930000185966492},{"id":"https://openalex.org/keywords/left-ventricular-volume","display_name":"left ventricular volume","score":0.7379999756813049},{"id":"https://openalex.org/keywords/echocardiography","display_name":"echocardiography","score":0.6759999990463257},{"id":"https://openalex.org/keywords/polysomnography","display_name":"polysomnography","score":0.9850000143051147},{"id":"https://openalex.org/keywords/dose-response-relationship","display_name":"dose-response relationship","score":0.43299999833106995},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.42899999022483826}],"concepts":[{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.747765302658081},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6725568771362305},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6390891075134277},{"id":"https://openalex.org/C2776377968","wikidata":"https://www.wikidata.org/wiki/Q618736","display_name":"Apnea\u2013hypopnea index","level":4,"score":0.552971363067627},{"id":"https://openalex.org/C2777935920","wikidata":"https://www.wikidata.org/wiki/Q213600","display_name":"Sleep apnea","level":2,"score":0.4750640094280243},{"id":"https://openalex.org/C2777382242","wikidata":"https://www.wikidata.org/wiki/Q6017816","display_name":"Index (typography)","level":2,"score":0.4150838255882263},{"id":"https://openalex.org/C2781326671","wikidata":"https://www.wikidata.org/wiki/Q754424","display_name":"Apnea","level":2,"score":0.3897397816181183},{"id":"https://openalex.org/C2778205975","wikidata":"https://www.wikidata.org/wiki/Q1754874","display_name":"Polysomnography","level":3,"score":0.24953868985176086},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/sleep/zsae067.0868","doi":"https://doi.org/10.1093/sleep/zsae067.0868","is_oa":true,"landing_page_url":"https://doi.org/10.1093/sleep/zsae067.0868","pdf_url":"https://academic.oup.com/sleep/article-pdf/47/Supplement_1/A372/57290516/zsae067.0868.pdf","source":{"id":"https://openalex.org/S42921845","display_name":"SLEEP","issn_l":"0161-8105","issn":["0161-8105","1550-9109"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SLEEP","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1093/sleep/zsae067.0868","doi":"https://doi.org/10.1093/sleep/zsae067.0868","is_oa":true,"landing_page_url":"https://doi.org/10.1093/sleep/zsae067.0868","pdf_url":"https://academic.oup.com/sleep/article-pdf/47/Supplement_1/A372/57290516/zsae067.0868.pdf","source":{"id":"https://openalex.org/S42921845","display_name":"SLEEP","issn_l":"0161-8105","issn":["0161-8105","1550-9109"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SLEEP","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4394979542.pdf","grobid_xml":"https://content.openalex.org/works/W4394979542.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1988873558","https://openalex.org/W2467936955","https://openalex.org/W2041750738","https://openalex.org/W2014113114","https://openalex.org/W2562923372","https://openalex.org/W1567602393","https://openalex.org/W4379799701","https://openalex.org/W2772296298","https://openalex.org/W2033900922","https://openalex.org/W1479826818"],"abstract_inverted_index":{"Abstract":[0],"Introduction":[1],"Left":[2],"atrial":[3],"(LA)":[4],"size":[5,195],"and":[6,62,74,88,94,116,131,134,161,176,193,223,310,313],"volume":[7,93,190,206,227,239,258,296],"are":[8,17,278],"of":[9,71,137],"interest":[10],"in":[11,204,214,225,237,256,294],"sleep-disordered":[12],"breathing":[13],"(SDB)":[14],"as":[15,106],"they":[16],"associated":[18,186,311],"with":[19,140,160,187,250,266,276],"cardiac":[20,282],"arrhythmias.":[21,283],"However,":[22],"whether":[23],"the":[24,72,83,100,125,135],"apnea-hypopnea":[25],"index":[26],"(AHI)":[27],"predicts":[28,292],"LA":[29,92,95,132,141,189,194,205,215,226,238,295,308],"longitudinal":[30],"changes":[31,142,203,213,224,293],"over":[32,143,207,240,297],"time":[33,173,208,241],"remains":[34],"unknown.":[35],"Methods":[36],"This":[37],"retrospective":[38],"cohort":[39],"study":[40],"includes":[41],"adults":[42],"(\u226518":[43],"years)":[44],"without":[45,162,231],"congestive":[46],"heart":[47],"failure":[48],"(CHF)":[49],"who":[50],"were":[51,97,121],"referred":[52],"for":[53,281,307,318],"a":[54,65,75,234,315],"diagnostic":[55],"in-laboratory":[56],"polysomnogram":[57],"(PSG)":[58],"between":[59,129,174,220,270],"January":[60],"2019":[61],"March":[63],"2020;":[64],"baseline":[66,126,138,175,291],"echocardiogram":[67,77],"within":[68],"one":[69,80],"year":[70,81],"PSG;":[73],"follow-up":[76,177],"more":[78],"than":[79],"after":[82],"initial":[84],"studies.":[85],"Clinical,":[86],"PSG":[87],"echocardiographic":[89],"variables,":[90],"including":[91],"size,":[96],"abstracted":[98],"from":[99],"medical":[101],"record.":[102],"SDB":[103,163,221,252,268,277,288],"was":[104,179,185,228],"classified":[105],"absent,":[107],"mild,":[108],"moderate,":[109],"or":[110],"severe":[111,251],"(AHI":[112,164],"\u22644.9/h,":[113],"5.0-14.9/h,":[114],"15.0-29.9/h,":[115],"\u226530/h,":[117],"respectively).":[118],"Regression":[119],"models":[120],"used":[122],"to":[123,321],"assess":[124],"cross-sectional":[127],"relationships":[128],"AHI":[130,139,184,200],"measures,":[133],"association":[136],"time.":[144,298],"Results":[145],"We":[146],"identified":[147],"103":[148],"patients":[149,275,304],"(58.8%":[150],"male,":[151],"median":[152,165,172],"age":[153],"66":[154],"years":[155,181],"(interquartile":[156],"range,":[157],"IQR":[158,167,244,261],"52-71))":[159],"19.9,":[166],"7.3":[168],"\u2013":[169,263],"35.6).":[170],"The":[171],"echocardiograms":[178],"3.2":[180],"(IQR":[182],"2.3-4.1).":[183],"larger":[188],"(\u03b2=0.64,":[191],"p=0.0002)":[192],"(\u03b2=0.08,":[196],"p=0.04)":[197],"at":[198,279,290,305],"baseline.":[199],"also":[201],"predicted":[202],"(\u03b2=0.57,":[209],"p=0.02),":[210],"but":[211],"not":[212],"size.":[216],"A":[217],"dose-dependent":[218],"relationship":[219],"severity":[222,289],"noted:":[229],"Individuals":[230,265],"OSA":[232],"demonstrated":[233,253],"slight":[235],"decrease":[236,322],"(median":[242,259],"-7,":[243],"-36":[245],"-":[246],"-5)":[247],"whereas":[248],"those":[249,271],"an":[254],"increase":[255],"LV":[257],"13,":[260],"-9":[262],"+18).":[264],"mild/moderate":[267],"fell":[269],"groups.":[272],"Conclusion":[273],"Many":[274],"risk":[280,306],"Our":[284],"results":[285],"indicate":[286],"that":[287],"These":[299],"findings":[300],"may":[301],"help":[302],"identify":[303],"enlargement":[309],"arrhythmias,":[312],"suggest":[314],"potential":[316],"opportunity":[317],"early":[319],"intervention":[320],"cardiovascular":[323],"risk.":[324],"Support":[325],"(if":[326],"any)":[327],"NIH":[328],"R25NS088248":[329]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-04-21T00:00:00"}