{"id":"https://openalex.org/W4394884434","doi":"https://doi.org/10.1016/j.mayocp.2023.12.009","title":"Blood Calcium, Genetic Risk, and Risk of Incident Kidney Stone: A Population-Based Cohort Study","display_name":"Blood Calcium, Genetic Risk, and Risk of Incident Kidney Stone: A Population-Based Cohort Study","publication_year":2024,"publication_date":"2024-04-17","ids":{"openalex":"https://openalex.org/W4394884434","doi":"https://doi.org/10.1016/j.mayocp.2023.12.009","pmid":"https://pubmed.ncbi.nlm.nih.gov/38639678"},"language":"en","primary_location":{"id":"doi:10.1016/j.mayocp.2023.12.009","doi":"https://doi.org/10.1016/j.mayocp.2023.12.009","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.mayocp.2023.12.009","pdf_url":"http://www.mayoclinicproceedings.org/article/S0025619623006109/pdf","source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.mayoclinicproceedings.org/article/S0025619623006109/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100330003","display_name":"Xi Cao","orcid":"https://orcid.org/0009-0008-8150-5778","observed_orcids":["https://orcid.org/0009-0008-8150-5778","https://orcid.org/0000-0003-2491-4301","https://orcid.org/0000-0003-2797-6380","https://orcid.org/0000-0002-9650-3897"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xi Cao","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100391311","display_name":"Si Li","orcid":"https://orcid.org/0000-0001-6579-2916","observed_orcids":["https://orcid.org/0000-0001-6579-2916"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Si Li","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102637945","display_name":"Yunlong Guan","orcid":"https://orcid.org/0009-0004-3743-3878","observed_orcids":["https://orcid.org/0009-0004-3743-3878"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yunlong Guan","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069015108","display_name":"Zhonghe Shao","orcid":"https://orcid.org/0009-0005-2013-6508","observed_orcids":["https://orcid.org/0009-0005-2013-6508"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhonghe Shao","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101950147","display_name":"Minghui Jiang","orcid":"https://orcid.org/0000-0002-7888-2408","observed_orcids":["https://orcid.org/0000-0002-7888-2408"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Minghui Jiang","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100415829","display_name":"Miao Wang","orcid":"https://orcid.org/0000-0002-0532-6312","observed_orcids":["https://orcid.org/0000-0002-0532-6312","https://orcid.org/0009-0001-1297-705X","https://orcid.org/0000-0002-1784-1178"]},"institutions":[{"id":"https://openalex.org/I4210129222","display_name":"Wuhan Union Hospital","ror":"https://ror.org/0371fqr87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129222"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Miao Wang","raw_affiliation_strings":["Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. Electronic address: wangmiaotj@163.com","Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. Electronic address: wangmiaotj@163.com","institution_ids":["https://openalex.org/I4210129222","https://openalex.org/I47720641"]},{"raw_affiliation_string":"Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008474331","display_name":"Xingjie Hao","orcid":"https://orcid.org/0000-0003-1535-9860","observed_orcids":["https://orcid.org/0000-0003-1535-9860"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xingjie Hao","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. Electronic address: xingjie@hust.edu.cn","Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. Electronic address: xingjie@hust.edu.cn","institution_ids":["https://openalex.org/I47720641"]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China","institution_ids":["https://openalex.org/I47720641"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5008474331","https://openalex.org/A5100415829"],"corresponding_institution_ids":["https://openalex.org/I4210129222","https://openalex.org/I47720641"],"apc_list":{"value":3300,"currency":"USD","value_usd":3300},"apc_paid":{"value":3300,"currency":"USD","value_usd":3300},"fwci":2.5921,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.88847801,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"99","issue":"8","first_page":"1248","last_page":"1260"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10606","display_name":"Kidney Stones and Urolithiasis Treatments","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10606","display_name":"Kidney Stones and Urolithiasis Treatments","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serum-calcium","display_name":"serum calcium","score":0.8190000057220459},{"id":"https://openalex.org/keywords/kidney-stones","display_name":"kidney stones","score":0.8349999785423279},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.765999972820282},{"id":"https://openalex.org/keywords/polygenic-risk-score","display_name":"polygenic risk score","score":0.9990000128746033},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9679999947547913},{"id":"https://openalex.org/keywords/hypercalcemia","display_name":"hypercalcemia","score":0.843999981880188},{"id":"https://openalex.org/keywords/nonlinear-relationship","display_name":"nonlinear relationship","score":0.4740000069141388}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9532701969146729},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.555229663848877},{"id":"https://openalex.org/C12174686","wikidata":"https://www.wikidata.org/wiki/Q1058438","display_name":"Risk assessment","level":2,"score":0.5550836324691772},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.5254242420196533},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.47689417004585266},{"id":"https://openalex.org/C2779403450","wikidata":"https://www.wikidata.org/wiki/Q178623","display_name":"Kidney stones","level":2,"score":0.42865073680877686},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34303176403045654},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.26423102617263794},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007669","descriptor_name":"Kidney Calculi","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D007669","descriptor_name":"Kidney Calculi","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007669","descriptor_name":"Kidney Calculi","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.mayocp.2023.12.009","doi":"https://doi.org/10.1016/j.mayocp.2023.12.009","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.mayocp.2023.12.009","pdf_url":"http://www.mayoclinicproceedings.org/article/S0025619623006109/pdf","source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},{"id":"pmid:38639678","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38639678","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic proceedings","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.mayocp.2023.12.009","doi":"https://doi.org/10.1016/j.mayocp.2023.12.009","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.mayocp.2023.12.009","pdf_url":"http://www.mayoclinicproceedings.org/article/S0025619623006109/pdf","source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G563345736","display_name":null,"funder_award_id":"82003561","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6768754572","display_name":null,"funder_award_id":"82273443","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G850656503","display_name":null,"funder_award_id":"2022gwzz01","funder_id":"https://openalex.org/F4320321883","funder_display_name":"Huazhong University of Science and Technology"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321883","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4394884434.pdf","grobid_xml":"https://content.openalex.org/works/W4394884434.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W30128323","https://openalex.org/W1151991771","https://openalex.org/W1236439116","https://openalex.org/W1997566955","https://openalex.org/W2007932581","https://openalex.org/W2034675748","https://openalex.org/W2045180107","https://openalex.org/W2067489213","https://openalex.org/W2074516286","https://openalex.org/W2076550141","https://openalex.org/W2079914273","https://openalex.org/W2082704080","https://openalex.org/W2095140900","https://openalex.org/W2099085143","https://openalex.org/W2102800616","https://openalex.org/W2103120948","https://openalex.org/W2116312562","https://openalex.org/W2147737790","https://openalex.org/W2148853530","https://openalex.org/W2153512596","https://openalex.org/W2156123452","https://openalex.org/W2171942415","https://openalex.org/W2172475396","https://openalex.org/W2319676870","https://openalex.org/W2419509011","https://openalex.org/W2582023030","https://openalex.org/W2621387950","https://openalex.org/W2785453084","https://openalex.org/W2895486342","https://openalex.org/W2909463307","https://openalex.org/W2944147909","https://openalex.org/W2981815988","https://openalex.org/W2999343670","https://openalex.org/W3035540983","https://openalex.org/W3035710287","https://openalex.org/W3082832108","https://openalex.org/W3205830700","https://openalex.org/W3210214395","https://openalex.org/W4206514582"],"related_works":["https://openalex.org/W4399797602","https://openalex.org/W6920421291","https://openalex.org/W3205830700","https://openalex.org/W7118135096","https://openalex.org/W7215038641","https://openalex.org/W4406788951","https://openalex.org/W7213597727","https://openalex.org/W2319676870","https://openalex.org/W4405319083","https://openalex.org/W2148196088"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"investigate":[2],"the":[3,18,35,70,89,114,124,176],"association":[4],"between":[5,224,263],"blood":[6,60,116,225,246,264],"calcium":[7,61,117,226,233,247,265],"concentration":[8,118,132,227,234,248,266],"and":[9,52,63,128,149,165,182,208,228,235,267],"incident":[10,56,221,241],"kidney":[11,57,108,138,158,193,222,242,268],"stone":[12,58,109,139,159,194,223,243,252,269],"as":[13,15],"well":[14],"to":[16,47,147,152,168,171,175,185,206,211],"assess":[17],"role":[19],"played":[20],"by":[21],"genetic":[22,187,199,229,258],"susceptibility.":[23,230],"METHODS:":[24],"We":[25],"performed":[26],"a":[27,95,216],"population-based":[28],"cohort":[29],"study":[30,76],"based":[31],"on":[32],"participants":[33,93],"from":[34,79],"UK":[36],"Biobank.":[37],"A":[38,260],"multivariable":[39],"Cox":[40],"proportional":[41],"hazards":[42],"regression":[43],"model":[44],"was":[45,73,77,166,215,271],"used":[46,167],"estimate":[48],"hazard":[49],"ratios":[50],"(HRs)":[51],"95%":[53],"CIs":[54],"of":[55,91,97,102,107,137,142,192,203,220],"for":[59,157],"level":[62],"polygenic":[64],"risk":[65,200,219,253,270],"score":[66],"(PRS).":[67],"In":[68],"addition,":[69],"potential":[71],"interaction":[72],"explored.":[74],"The":[75,155],"conducted":[78],"January":[80],"28,":[81],"2023,":[82],"through":[83],"June":[84],"4,":[85],"2023.":[86],"RESULTS:":[87],"During":[88],"follow-up":[90,101],"423,301":[92],"with":[94,113,140,179,196,201,240],"total":[96],"5,490,332":[98],"person-years":[99],"(median":[100],"13.4":[103],"years),":[104],"4502":[105],"cases":[106],"were":[110],"recorded.":[111],"Compared":[112],"low":[115,197],"group":[119],"(first":[120],"tertile),":[121],"individuals":[122,170],"in":[123,254],"high":[125,180,257],"(third":[126],"tertile)":[127,131],"moderate":[129,183],"(second":[130],"groups":[133,173],"had":[134,189],"higher":[135],"risks":[136,188,191],"HRs":[141,202],"1.24":[143],"(95%":[144],"CI,":[145],"1.15":[146],"1.33)":[148],"1.11":[150],"(1.04":[151],"1.20),":[153],"respectively.":[154,213],"PRS":[156,236],"contained":[160],"40":[161],"independent":[162],"single-nucleotide":[163],"polymorphisms":[164],"assign":[169],"3":[172],"according":[174],"quintile.":[177],"Participants":[178],"(Q5)":[181],"(Q2":[184],"Q4)":[186],"increased":[190],"compared":[195],"(Q1)":[198],"1.70":[204],"(1.53":[205],"1.89)":[207],"1.31":[209],"(1.20":[210],"1.44),":[212],"There":[214],"joint":[217],"cumulative":[218],"CONCLUSIONS:":[231],"Blood":[232],"are":[237],"significantly":[238],"associated":[239],"risk.":[244,259],"Excessive":[245],"might":[249],"bring":[250],"additional":[251],"populations":[255],"at":[256],"nonlinear":[261],"correlation":[262],"indicated.":[272]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2024-04-18T00:00:00"}