{"id":"https://openalex.org/W4394800722","doi":"https://doi.org/10.1097/01.ju.0001009492.49624.4b.01","title":"MP51-01 A NOVEL URINARY BIOMARKER FOR THE DETECTION AND SURVEILLANCE OF RENAL CELL CARCINOMA","display_name":"MP51-01 A NOVEL URINARY BIOMARKER FOR THE DETECTION AND SURVEILLANCE OF RENAL CELL CARCINOMA","publication_year":2024,"publication_date":"2024-04-15","ids":{"openalex":"https://openalex.org/W4394800722","doi":"https://doi.org/10.1097/01.ju.0001009492.49624.4b.01"},"language":"en","primary_location":{"id":"doi:10.1097/01.ju.0001009492.49624.4b.01","doi":"https://doi.org/10.1097/01.ju.0001009492.49624.4b.01","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.ju.0001009492.49624.4b.01","pdf_url":null,"source":{"id":"https://openalex.org/S30525748","display_name":"The Journal of Urology","issn_l":"0022-5347","issn":["0022-5347","1527-3792"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Urology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005485529","display_name":"Ethan H. Vargo","orcid":"https://orcid.org/0000-0002-2084-5401","observed_orcids":["https://orcid.org/0000-0002-2084-5401"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ethan Vargo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109705083","display_name":"Wen C. Burns","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wen C. Burns","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025826877","display_name":"Aleksandra Klim","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aleksandra Klim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Linda Black","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Linda Black","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090973623","display_name":"Rebekah Keller","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rebekah Keller","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089540737","display_name":"Robert Sherburne Figenshau","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Sherburne Figenshau","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5049688133","display_name":"Michael Hiroshi Johnson","orcid":"https://orcid.org/0000-0003-4393-2468","observed_orcids":["https://orcid.org/0000-0003-4393-2468"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Johnson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.08107509,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"211","issue":"5S","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10449","display_name":"Renal cell carcinoma treatment","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10449","display_name":"Renal cell carcinoma treatment","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/renal-cell-carcinoma","display_name":"renal cell carcinoma","score":0.9980000257492065},{"id":"https://openalex.org/keywords/urinary-biomarkers","display_name":"urinary biomarkers","score":0.949999988079071},{"id":"https://openalex.org/keywords/postoperative-follow-up","display_name":"postoperative follow-up","score":0.5920000076293945},{"id":"https://openalex.org/keywords/early-cancer-detection","display_name":"early cancer detection","score":0.5320000052452087},{"id":"https://openalex.org/keywords/robot-assisted-partial-nephrectomy","display_name":"robot-assisted partial nephrectomy","score":0.8560000061988831},{"id":"https://openalex.org/keywords/robotic-radical-nephrectomy","display_name":"robotic radical nephrectomy","score":0.9729999899864197},{"id":"https://openalex.org/keywords/microscopic-hematuria","display_name":"microscopic hematuria","score":0.734000027179718},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.34200000762939453},{"id":"https://openalex.org/keywords/lymphovascular-invasion","display_name":"lymphovascular invasion","score":0.7799999713897705},{"id":"https://openalex.org/keywords/surgical-margins","display_name":"surgical margins","score":0.5860000252723694},{"id":"https://openalex.org/keywords/tumor-grade","display_name":"tumor grade","score":0.37400001287460327},{"id":"https://openalex.org/keywords/microrna-biomarkers","display_name":"microRNA biomarkers","score":0.3240000009536743},{"id":"https://openalex.org/keywords/tumor-suppressor-genes","display_name":"tumor suppressor","score":0.3140000104904175}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7249174118041992},{"id":"https://openalex.org/C2780227381","wikidata":"https://www.wikidata.org/wiki/Q1357376","display_name":"Nephrectomy","level":3,"score":0.6853070259094238},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.6296740770339966},{"id":"https://openalex.org/C2777472916","wikidata":"https://www.wikidata.org/wiki/Q1164529","display_name":"Renal cell carcinoma","level":2,"score":0.6182286739349365},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.602210283279419},{"id":"https://openalex.org/C2781278892","wikidata":"https://www.wikidata.org/wiki/Q18556340","display_name":"Clear cell renal cell carcinoma","level":3,"score":0.5725265145301819},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.5493714809417725},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.5299018025398254},{"id":"https://openalex.org/C2778560582","wikidata":"https://www.wikidata.org/wiki/Q18347894","display_name":"Clear cell","level":3,"score":0.45596617460250854},{"id":"https://openalex.org/C2781068499","wikidata":"https://www.wikidata.org/wiki/Q3242950","display_name":"Kidney cancer","level":3,"score":0.4365631639957428},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.41060739755630493},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31790876388549805},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.22583767771720886},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06304389238357544},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/01.ju.0001009492.49624.4b.01","doi":"https://doi.org/10.1097/01.ju.0001009492.49624.4b.01","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.ju.0001009492.49624.4b.01","pdf_url":null,"source":{"id":"https://openalex.org/S30525748","display_name":"The Journal of Urology","issn_l":"0022-5347","issn":["0022-5347","1527-3792"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Urology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4306404866","https://openalex.org/W2006034206","https://openalex.org/W4415690251","https://openalex.org/W3023199915","https://openalex.org/W3043470353","https://openalex.org/W2792979838","https://openalex.org/W2396783233","https://openalex.org/W2059117379","https://openalex.org/W2070121166","https://openalex.org/W2970154388"],"abstract_inverted_index":{"You":[0],"have":[1],"accessJournal":[2],"of":[3,92,148,198,226,237,255,311,350,359,373,383,388],"UrologyKidney":[4],"Cancer:":[5],"Epidemiology":[6],"&":[7,408],"Evaluation/Staging/Surveillance":[8],"II":[9],"(MP51)1":[10],"May":[11],"2024MP51-01":[12],"A":[13,224],"NOVEL":[14],"URINARY":[15],"BIOMARKER":[16],"FOR":[17],"THE":[18],"DETECTION":[19],"AND":[20,88],"SURVEILLANCE":[21],"OF":[22],"RENAL":[23],"CELL":[24],"CARCINOMA":[25],"Ethan":[26,43,421],"Vargo,":[27],"Wen":[28,47,428],"C.":[29,48,50,429],"Burns,":[30],"Aleksandra":[31,53,436],"Klim,":[32],"Linda":[33,57,443],"Black,":[34],"Rebekah":[35,61,450],"Keller,":[36],"R.":[37,65,457],"Sherburne":[38,66,68,458],"Figenshau,":[39],"and":[40,71,98,114,138,146,156,185,201,218,232,286,292,338,381,398,416],"Michael":[41,72,465],"Johnson":[42,74,466],"VargoEthan":[44],"Vargo":[45,422],",":[46,52,56,60,64,70],"BurnsWen":[49],"Burns":[51,430],"KlimAleksandra":[54],"Klim":[55,437],"BlackLinda":[58],"Black":[59,444],"KellerRebekah":[62],"Keller":[63,451],"FigenshauR.":[67],"Figenshau":[69,459],"JohnsonMichael":[73],"View":[75],"All":[76,294,473],"Author":[77,419],"Informationhttps://doi.org/10.1097/01.JU.0001009492.49624.4b.01AboutPDF":[78],"ToolsAdd":[79],"to":[80,104,129,161,187,322],"favoritesDownload":[81],"CitationsTrack":[82],"CitationsPermissionsReprints":[83],"ShareFacebookLinked":[84],"InTwitterEmail":[85],"Abstract":[86],"INTRODUCTION":[87],"OBJECTIVE:":[89],"Effective":[90],"methods":[91],"renal":[93,126,306,362],"cell":[94,165,272,281,290],"carcinoma":[95],"(RCC)":[96],"detection":[97],"surveillance":[99,382],"are":[100],"needed.":[101],"We":[102],"aimed":[103],"highlight":[105],"a":[106,172,230,315,374],"novel":[107,154,375],"cell-specific":[108],"urinary":[109,163,376],"biomarker":[110,377],"for":[111,251,378],"RCC":[112,282,291],"diagnosis":[113,380],"post-treatment":[115],"follow-up.":[116],"METHODS:":[117],"Urine":[118,177,206],"samples":[119,178,207],"were":[120,150,179,204,221],"collected":[121,180],"from":[122,208],"patients":[123,213,228,239,269,295,304,313,360],"with":[124,283,305,342,361],"cT1a-cT2N0M0":[125],"masses":[127,363],"prior":[128],"robotic":[130,134],"partial":[131],"(RP)":[132],"or":[133],"radical":[135],"nephrectomy":[136,212],"(RRN)":[137],"following":[139],"surgery.":[140],"Patient":[141],"characteristics":[142,191],"including":[143,192],"gender,":[144],"laterality,":[145],"presence":[147,197],"microhematuria":[149,252],"assessed.":[151],"Samples":[152],"underwent":[153,240,245],"filtering":[155],"polymerase":[157],"chain":[158],"reaction":[159],"testing":[160],"determine":[162],"tumor":[164,335,344],"density":[166],"(UTC/50":[167],"ml)":[168],"(UTCD),":[169],"reported":[170],"as":[171,215,334],"log":[173],"value":[174],"(log":[175],"eUTCs).":[176],"at":[181],"different":[182],"times":[183],"postoperatively":[184],"compared":[186],"preoperative":[188,231,259,301],"levels.":[189],"Postoperative":[190],"final":[193],"pathology,":[194],"histology,":[195],"grade,":[196],"lymphovascular":[199],"invasion,":[200],"margin":[202],"status":[203],"examined.":[205],"10":[209,227,238,312],"healthy":[210],"donor":[211],"served":[214],"controls.":[216],"Paired":[217],"unpaired":[219],"t-tests":[220],"performed.":[222],"RESULTS:":[223],"total":[225],"provided":[229],"postoperative":[233,320],"urine":[234],"sample.":[235],"Nine":[236],"RPN,":[241],"while":[242],"one":[243,274,278,287],"patient":[244,275,279,288],"RRN.":[246],"Preoperative":[247],"urinalysis":[248],"was":[249,262,308,328,354],"negative":[250,297],"in":[253,303,318,332],"seven":[254],"eight":[256],"cases.":[257],"Mean":[258,300,348],"mass":[260],"size":[261,336],"3.8":[263],"centimeters":[264],"(range":[265],"1.9-8.8":[266],"cm).":[267],"Seven":[268],"harbored":[270],"clear":[271,280,289],"RCC,":[273,277],"papillary":[276],"leiomyomatous":[284],"features,":[285],"oncocytoma.":[293],"had":[296],"surgical":[298],"margins.":[299],"UTCD":[302,321,333,340,349],"tumors":[307],"3.69.":[309],"Eight":[310],"experienced":[314],"significant":[316],"decrease":[317],"mean":[319,339],"1.94":[323],"(p=0.01)":[324],"(Table":[325],"1).":[326,347],"There":[327],"an":[329],"overall":[330],"uptrend":[331],"increased,":[337],"increased":[341],"higher":[343],"grades":[345],"(Figure":[346],"the":[351,370,379],"control":[352],"group":[353],"significantly":[355],"lower":[356],"than":[357],"that":[358],"preoperatively":[364],"(p<0.01).":[365],"CONCLUSIONS:":[366],"This":[367],"study":[368],"demonstrates":[369],"exciting":[371],"potential":[372],"RCC.":[384],"Download":[385],"PPT":[386],"Source":[387],"Funding:":[389],"N/A":[390],"\u00a9":[391],"2024":[392,410],"by":[393,411,425,433,440,447,454,462,469],"American":[394,412],"Urological":[395,413],"Association":[396,414],"Education":[397,415],"Research,":[399,417],"Inc.FiguresReferencesRelatedDetails":[400],"Volume":[401],"211Issue":[402],"5SMay":[403],"2024Page:":[404],"e841":[405],"Advertisement":[406,474],"Copyright":[407],"Permissions\u00a9":[409],"Inc.Metrics":[418],"Information":[420],"More":[423,431,438,445,452,460,467],"articles":[424,432,439,446,453,461,468],"this":[426,434,441,448,455,463,470],"author":[427,435,442,449,456,464,471],"Expand":[472],"PDF":[475],"downloadLoading":[476],"...":[477]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2024-04-16T00:00:00"}