{"id":"https://openalex.org/W4394792142","doi":"https://doi.org/10.29296/24999490-2024-02-03","title":"Biomarkers of oxidative stress and proteopathies in the diagnosis of neurodegenerative diseases","display_name":"Biomarkers of oxidative stress and proteopathies in the diagnosis of neurodegenerative diseases","publication_year":2024,"publication_date":"2024-04-04","ids":{"openalex":"https://openalex.org/W4394792142","doi":"https://doi.org/10.29296/24999490-2024-02-03"},"language":"en","primary_location":{"id":"doi:10.29296/24999490-2024-02-03","doi":"https://doi.org/10.29296/24999490-2024-02-03","is_oa":true,"landing_page_url":"https://doi.org/10.29296/24999490-2024-02-03","pdf_url":"https://molmedjournal.ru/en/system/files/24999490-2024-02-03_0.pdf","source":{"id":"https://openalex.org/S4210170970","display_name":"Molekulyarnaya Meditsina (Molecular medicine)","issn_l":"1728-2918","issn":["1728-2918","2499-9490"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-1"],"host_organization":"https://openalex.org/P4327874082","host_organization_name":"Russkiy Vrach Publishing House","host_organization_lineage":["https://openalex.org/P4327874082"],"host_organization_lineage_names":["Russkiy Vrach Publishing House"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molekulyarnaya Meditsina (Molecular medicine)","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W4394792142"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://molmedjournal.ru/en/system/files/24999490-2024-02-03_0.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012445917","display_name":"\u0417. \u0418. \u041c\u0438\u043a\u0430\u0448\u0438\u043d\u043e\u0432\u0438\u0447","orcid":"https://orcid.org/0000-0001-9906-8248","observed_orcids":["https://orcid.org/0000-0001-9906-8248"]},"institutions":[{"id":"https://openalex.org/I16478408","display_name":"Rostov State Medical University","ror":"https://ror.org/046a1ah60","country_code":"RU","type":"education","lineage":["https://openalex.org/I16478408"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Z.I. Mikashinovich","raw_affiliation_strings":["Federal State Budgetary Educational Institution of Higher Professional Education \u00abRostov State Medical University\u00bb Ministry of Health of the Russian Federation, Russian Federation, Nakhichevansky per. 29, Rostov-on-Don"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal State Budgetary Educational Institution of Higher Professional Education \u00abRostov State Medical University\u00bb Ministry of Health of the Russian Federation, Russian Federation, Nakhichevansky per. 29, Rostov-on-Don","institution_ids":["https://openalex.org/I16478408","https://openalex.org/I4210117042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015780282","display_name":"\u041d. \u0420. \u0422\u0435\u043b\u0435\u0441\u043c\u0430\u043d\u0438\u0447","orcid":"https://orcid.org/0000-0002-1906-6312","observed_orcids":["https://orcid.org/0000-0002-1906-6312"]},"institutions":[{"id":"https://openalex.org/I16478408","display_name":"Rostov State Medical University","ror":"https://ror.org/046a1ah60","country_code":"RU","type":"education","lineage":["https://openalex.org/I16478408"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"N.R. Telesmanich","raw_affiliation_strings":["Federal State Budgetary Educational Institution of Higher Professional Education \u00abRostov State Medical University\u00bb Ministry of Health of the Russian Federation, Russian Federation, Nakhichevansky per. 29, Rostov-on-Don"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal State Budgetary Educational Institution of Higher Professional Education \u00abRostov State Medical University\u00bb Ministry of Health of the Russian Federation, Russian Federation, Nakhichevansky per. 29, Rostov-on-Don","institution_ids":["https://openalex.org/I16478408","https://openalex.org/I4210117042"]}]},{"author_position":"middle","author":{"id":null,"display_name":"O.B. Smirnova","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16478408","display_name":"Rostov State Medical University","ror":"https://ror.org/046a1ah60","country_code":"RU","type":"education","lineage":["https://openalex.org/I16478408"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"O.B. Smirnova","raw_affiliation_strings":["Federal State Budgetary Educational Institution of Higher Professional Education \u00abRostov State Medical University\u00bb Ministry of Health of the Russian Federation, Russian Federation, Nakhichevansky per. 29, Rostov-on-Don"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal State Budgetary Educational Institution of Higher Professional Education \u00abRostov State Medical University\u00bb Ministry of Health of the Russian Federation, Russian Federation, Nakhichevansky per. 29, Rostov-on-Don","institution_ids":["https://openalex.org/I16478408","https://openalex.org/I4210117042"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043249196","display_name":"\u0415. \u0410. \u0427\u0435\u0440\u043d\u043e\u0433\u0443\u0431\u043e\u0432\u0430","orcid":"https://orcid.org/0000-0001-5128-4910","observed_orcids":["https://orcid.org/0000-0001-5128-4910"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I2799343180","display_name":"Southern Scientific Center","ror":"https://ror.org/053nrfb18","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I2799343180","https://openalex.org/I4210160366"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"E.A. Chernogubova","raw_affiliation_strings":["Federal State Budgetary Institution of Science \u00abFederal Research Center Southern Scientific Center of the Russian Academy of Sciences\u00bb of the Ministry of Science and Higher Education of the Russian Federation, Russian Federation, 344006, Rostov-on-Don, Chekhov Ave., 41"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal State Budgetary Institution of Science \u00abFederal Research Center Southern Scientific Center of the Russian Academy of Sciences\u00bb of the Ministry of Science and Higher Education of the Russian Federation, Russian Federation, 344006, Rostov-on-Don, Chekhov Ave., 41","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I2799343180"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3268,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.46001864,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":null,"issue":null,"first_page":"16","last_page":"22"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.5346999764442444,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.5346999764442444,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14144","display_name":"Neurological Disease Mechanisms and Treatments","score":0.11150000244379044,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.08399999886751175,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.9639999866485596},{"id":"https://openalex.org/keywords/oxidative-stress-biomarkers","display_name":"oxidative stress biomarkers","score":0.9440000057220459},{"id":"https://openalex.org/keywords/proteinopathies","display_name":"proteinopathies","score":0.7739999890327454},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.7200000286102295},{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"multiple sclerosis","score":0.6629999876022339},{"id":"https://openalex.org/keywords/amyotrophic-lateral-sclerosis","display_name":"amyotrophic lateral sclerosis","score":1.0},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":1.0},{"id":"https://openalex.org/keywords/glutathione","display_name":"glutathione","score":0.7039999961853027},{"id":"https://openalex.org/keywords/myeloperoxidase","display_name":"myeloperoxidase","score":0.9480000138282776},{"id":"https://openalex.org/keywords/isoprostanes","display_name":"isoprostanes","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.9079999923706055},{"id":"https://openalex.org/keywords/metal-metabolism","display_name":"metal metabolism","score":0.4519999921321869},{"id":"https://openalex.org/keywords/iron-accumulation","display_name":"iron accumulation","score":0.5839999914169312},{"id":"https://openalex.org/keywords/amyloid-beta","display_name":"amyloid-beta","score":0.8240000009536743},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.7990000247955322},{"id":"https://openalex.org/keywords/redox-homeostasis","display_name":"redox homeostasis","score":0.8349999785423279},{"id":"https://openalex.org/keywords/salivary-biomarkers","display_name":"salivary biomarkers","score":0.921999990940094},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.628000020980835},{"id":"https://openalex.org/keywords/atypical-disease-course","display_name":"atypical disease course","score":0.6990000009536743}],"concepts":[{"id":"https://openalex.org/C2776925932","wikidata":"https://www.wikidata.org/wiki/Q1755122","display_name":"Neurodegeneration","level":3,"score":0.905822217464447},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.7390768527984619},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6880968809127808},{"id":"https://openalex.org/C2780596555","wikidata":"https://www.wikidata.org/wiki/Q206901","display_name":"Amyotrophic lateral sclerosis","level":3,"score":0.6480981707572937},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5425899028778076},{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.5227482318878174},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5007951259613037},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.49106884002685547},{"id":"https://openalex.org/C87753298","wikidata":"https://www.wikidata.org/wiki/Q17157137","display_name":"Neuroinflammation","level":3,"score":0.4383878707885742},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.37551432847976685},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2688581943511963},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.24008700251579285},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1589318811893463}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.29296/24999490-2024-02-03","doi":"https://doi.org/10.29296/24999490-2024-02-03","is_oa":true,"landing_page_url":"https://doi.org/10.29296/24999490-2024-02-03","pdf_url":"https://molmedjournal.ru/en/system/files/24999490-2024-02-03_0.pdf","source":{"id":"https://openalex.org/S4210170970","display_name":"Molekulyarnaya Meditsina (Molecular medicine)","issn_l":"1728-2918","issn":["1728-2918","2499-9490"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-1"],"host_organization":"https://openalex.org/P4327874082","host_organization_name":"Russkiy Vrach Publishing House","host_organization_lineage":["https://openalex.org/P4327874082"],"host_organization_lineage_names":["Russkiy Vrach Publishing House"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molekulyarnaya Meditsina (Molecular medicine)","raw_type":"journal-article"},{"id":"pmh:https://cyberleninka.ru/article/n/biomarkery-okislitelnogo-stressa-i-proteopatiy-v-diagnostike-neyrodegenerativnyh-zabolevaniy","doi":null,"is_oa":true,"landing_page_url":"https://cyberleninka.ru/article/n/biomarkery-okislitelnogo-stressa-i-proteopatiy-v-diagnostike-neyrodegenerativnyh-zabolevaniy","pdf_url":"https://cyberleninka.ru/article/n/biomarkery-okislitelnogo-stressa-i-proteopatiy-v-diagnostike-neyrodegenerativnyh-zabolevaniy/pdf","source":{"id":"https://openalex.org/S4210170970","display_name":"Molekulyarnaya Meditsina (Molecular medicine)","issn_l":"1728-2918","issn":["1728-2918","2499-9490"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-1"],"host_organization":"https://openalex.org/P4327874082","host_organization_name":"Russkiy Vrach Publishing House","host_organization_lineage":["https://openalex.org/P4327874082"],"host_organization_lineage_names":["Russkiy Vrach Publishing House"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"}],"best_oa_location":{"id":"doi:10.29296/24999490-2024-02-03","doi":"https://doi.org/10.29296/24999490-2024-02-03","is_oa":true,"landing_page_url":"https://doi.org/10.29296/24999490-2024-02-03","pdf_url":"https://molmedjournal.ru/en/system/files/24999490-2024-02-03_0.pdf","source":{"id":"https://openalex.org/S4210170970","display_name":"Molekulyarnaya Meditsina (Molecular medicine)","issn_l":"1728-2918","issn":["1728-2918","2499-9490"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-1"],"host_organization":"https://openalex.org/P4327874082","host_organization_name":"Russkiy Vrach Publishing House","host_organization_lineage":["https://openalex.org/P4327874082"],"host_organization_lineage_names":["Russkiy Vrach Publishing House"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molekulyarnaya Meditsina (Molecular medicine)","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.979200005531311,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4394792142.pdf","grobid_xml":"https://content.openalex.org/works/W4394792142.grobid-xml"},"referenced_works_count":45,"referenced_works":["https://openalex.org/W1492890499","https://openalex.org/W1811596609","https://openalex.org/W1966582549","https://openalex.org/W1969622888","https://openalex.org/W1987787559","https://openalex.org/W1990500425","https://openalex.org/W1997712262","https://openalex.org/W2010254632","https://openalex.org/W2026406888","https://openalex.org/W2083872992","https://openalex.org/W2091902711","https://openalex.org/W2094249394","https://openalex.org/W2112810459","https://openalex.org/W2139201242","https://openalex.org/W2142271367","https://openalex.org/W2159518687","https://openalex.org/W2168082049","https://openalex.org/W2338406914","https://openalex.org/W2577574841","https://openalex.org/W2587868283","https://openalex.org/W2604387140","https://openalex.org/W2689411781","https://openalex.org/W2939834882","https://openalex.org/W2981752586","https://openalex.org/W2991851654","https://openalex.org/W3020087588","https://openalex.org/W3027208162","https://openalex.org/W3036921563","https://openalex.org/W3038541259","https://openalex.org/W3088074241","https://openalex.org/W3093396694","https://openalex.org/W3104126768","https://openalex.org/W3107201314","https://openalex.org/W3125753227","https://openalex.org/W3195017168","https://openalex.org/W3197690077","https://openalex.org/W4206625382","https://openalex.org/W4220742426","https://openalex.org/W4319159217","https://openalex.org/W4323062046","https://openalex.org/W4323926001","https://openalex.org/W4360603401","https://openalex.org/W4377023441","https://openalex.org/W4380668277","https://openalex.org/W4380871455"],"related_works":["https://openalex.org/W3022141444","https://openalex.org/W7170293457","https://openalex.org/W2418619249","https://openalex.org/W870837887","https://openalex.org/W2156015128","https://openalex.org/W3034391002","https://openalex.org/W4226355999","https://openalex.org/W2566607313","https://openalex.org/W2905465378"],"abstract_inverted_index":{"Introduction.":[0],"Despite":[1],"numerous":[2],"studies":[3,72],"in":[4,132,164,178,189,217,235,270,294,326,362,388],"the":[5,10,29,35,58,66,95,114,125,152,155,159,179,183,190,194,213,230,244,247,254,260,271,277,280,286,289,295,299,302,305,310,317,333,369,378,382,389,393,402],"field":[6,272],"of":[7,13,23,52,57,68,77,88,107,128,135,154,161,173,175,185,193,215,220,233,249,256,262,273,279,291,301,312,319,335,346,368,373,384,392,401],"neurodegenerative":[8,136],"diseases,":[9],"exact":[11],"mechanisms":[12,127],"these":[14],"processes":[15],"have":[16],"not":[17],"yet":[18],"been":[19,122],"identified.":[20],"The":[21,63,149,171,209,344],"purpose":[22],"this":[24],"review":[25,64,210],"is":[26,169,196,285,316],"to":[27,33,212,259,398,404],"analyze":[28],"methodological":[30],"approaches":[31],"necessary":[32],"revise":[34],"traditional":[36],"and":[37,42,54,61,70,80,91,100,146,158,166,188,207,222,282,304,341,350,359,365,371],"create":[38],"new":[39,348,374],"reliable":[40],"prognostic":[41,283,349],"diagnostic":[43,314,351],"algorithms":[44],"that":[45],"reflect":[46],"pathogenetic":[47],"features":[48,160],"at":[49],"different":[50],"stages":[51,391],"neurodegeneration":[53],"atypical":[55,191,396],"course":[56,192],"disease.":[59,148],"Material":[60],"methods.":[62],"highlights":[65],"results":[67],"clinical":[69,379],"experimental":[71],"obtained":[73],"using":[74],"a":[75,133],"complex":[76],"clinical,":[78],"laboratory":[79,358],"instrumental":[81,360],"methods":[82,315],"with":[83,237,298,355,395],"an":[84,323],"emphasis":[85],"on":[86,253,288,377],"markers":[87,174,200,375,387],"oxidative":[89,156,176],"stress":[90,177,258],"proteopathy.":[92],"In":[93],"preparing":[94],"materials,":[96],"sources":[97],"from":[98],"international":[99],"domestic":[101],"databases":[102],"were":[103],"used:":[104],"Scopus,":[105],"Web":[106],"Science,":[108],"Pub":[109],"Medline,":[110],"RSCI":[111],"mainly":[112],"for":[113,246,275,309],"last":[115],"15":[116],"years.":[117],"Results.":[118],"An":[119,266],"idea":[120],"has":[121,329],"formed":[123],"about":[124],"molecular":[126],"neural":[129],"tissue":[130],"regression":[131],"number":[134],"diseases":[137],"such":[138,225,338],"as":[139,226,243,322,339],"multiple":[140],"sclerosis,":[141,144],"amyotrophic":[142],"lateral":[143],"Alzheimer\u2019s":[145],"Parkinson\u2019s":[147],"relationship":[150],"between":[151],"parameters":[153],"process":[157,184],"metal-energy":[162],"shifts":[163,293],"organs":[165],"organ":[167],"systems":[168],"demonstrated.":[170],"role":[172],"early":[180,390],"stages,":[181],"when":[182],"inflammation":[186],"prevails":[187],"disease,":[195,394,403],"shown.":[197],"Valuable":[198],"biochemical":[199],"are":[201,264,353],"cytokines,":[202],"glutathione":[203],"levels,":[204],"myeloperoxidase":[205],"activation,":[206],"isoprostanes.":[208],"points":[211],"prospect":[214],"including":[216,357],"screening":[218],"indicators":[219],"iron":[221],"other":[223],"metals":[224],"Zn,":[227],"Mg,":[228],"affecting":[229],"clinic":[231],"accumulation":[232],"\u03b2-amyloid,":[234],"connection":[236],"which":[238,328],"they":[239],"can":[240],"be":[241],"considered":[242],"basis":[245],"progression":[248],"neurodegeneration.":[250],"New":[251],"data":[252,287],"contribution":[255],"halogenating":[257],"pathogenesis":[261],"neuroinflammation":[263],"presented.":[265],"aspect":[267],"requiring":[268],"development":[269],"biomarkers":[274],"assessing":[276],"duration":[278,300],"disease":[281,303],"prospects":[284,345],"correlation":[290],"metabolic":[292],"intestinal":[296],"microbiota":[297],"inflammatory":[306],"process.":[307],"Essential":[308],"creation":[311],"express":[313],"determination":[318],"redox":[320],"balance":[321],"integral":[324],"marker":[325],"saliva,":[327],"obvious":[330],"advantages":[331],"over":[332],"use":[334],"biological":[336],"fluids,":[337],"liquor":[340,364],"serum.":[342],"Conclusion.":[343],"creating":[347],"schemes":[352],"associated":[354],"complexes,":[356],"methods,":[361],"blood,":[363],"saliva.":[366],"Evaluation":[367],"sensitivity":[370],"specificity":[372],"depending":[376],"diagnosis":[380],"allows":[381],"selection":[383],"pathogenetically":[385],"significant":[386],"neurodegeneration,":[397],"establish":[399],"subtypes":[400],"carry":[405],"out":[406],"their":[407],"differential":[408],"diagnosis.":[409]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2024-04-14T00:00:00"}