{"id":"https://openalex.org/W4394774964","doi":"https://doi.org/10.31857/s0006302923010180","title":"Pathogenetic mechanisms of burn disease associated with oxidative membrane damage and ways of their correction","display_name":"Pathogenetic mechanisms of burn disease associated with oxidative membrane damage and ways of their correction","publication_year":2023,"publication_date":"2023-02-15","ids":{"openalex":"https://openalex.org/W4394774964","doi":"https://doi.org/10.31857/s0006302923010180"},"language":"en","primary_location":{"id":"doi:10.31857/s0006302923010180","doi":"https://doi.org/10.31857/s0006302923010180","is_oa":false,"landing_page_url":"https://doi.org/10.31857/s0006302923010180","pdf_url":null,"source":{"id":"https://openalex.org/S184337958","display_name":"\u0411\u0438\u043e\u0444\u0438\u0437\u0438\u043a\u0430","issn_l":"0006-3029","issn":["0006-3029"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319820","host_organization_name":"MAIK Nauka/Interperiodica","host_organization_lineage":["https://openalex.org/P4310319820","https://openalex.org/P4310320267"],"host_organization_lineage_names":["MAIK Nauka/Interperiodica","Pleiades Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"\u0411\u0438\u043e\u0444\u0438\u0437\u0438\u043a\u0430","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018743800","display_name":"Daria V. Vilyanen","orcid":"https://orcid.org/0000-0002-7020-6368","observed_orcids":["https://orcid.org/0000-0002-7020-6368"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210110501","display_name":"Institute of Basic Biological Problems","ror":"https://ror.org/01a0xxp39","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110501","https://openalex.org/I4210129690"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"D. V Vilyanen","raw_affiliation_strings":["Institute of Fundamental Problems of Biology, Russian Academy of Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Fundamental Problems of Biology, Russian Academy of Sciences","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210110501"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092682743","display_name":"N. I. Pashkevich","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116198","display_name":"Vitebsk State Medical University","ror":"https://ror.org/02d8ecr17","country_code":"BY","type":"education","lineage":["https://openalex.org/I4210116198"]}],"countries":["BY"],"is_corresponding":false,"raw_author_name":"N. I Pashkevich","raw_affiliation_strings":["Vitebsk State Order of Peoples\u2019 Friendship Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vitebsk State Order of Peoples\u2019 Friendship Medical University","institution_ids":["https://openalex.org/I4210116198"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083559443","display_name":"Maria M. Borisova\u2010Mubarakshina","orcid":"https://orcid.org/0000-0002-8524-3591","observed_orcids":["https://orcid.org/0000-0002-8524-3591"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210110501","display_name":"Institute of Basic Biological Problems","ror":"https://ror.org/01a0xxp39","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110501","https://openalex.org/I4210129690"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"M. M Borisova-mubarakshina","raw_affiliation_strings":["Institute of Fundamental Problems of Biology, Russian Academy of Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Fundamental Problems of Biology, Russian Academy of Sciences","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210110501"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038072395","display_name":"\u041e\u0441\u043e\u0447\u0443\u043a \u0421\u0435\u0440\u0433\u0435\u0439 \u0421\u0442\u0435\u0444\u0430\u043d\u043e\u0432\u0438\u0447","orcid":"https://orcid.org/0000-0003-2074-3832","observed_orcids":["https://orcid.org/0000-0003-2074-3832"]},"institutions":[{"id":"https://openalex.org/I4210116198","display_name":"Vitebsk State Medical University","ror":"https://ror.org/02d8ecr17","country_code":"BY","type":"education","lineage":["https://openalex.org/I4210116198"]}],"countries":["BY"],"is_corresponding":false,"raw_author_name":"S. S Osochuk","raw_affiliation_strings":["Vitebsk State Order of Peoples\u2019 Friendship Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vitebsk State Order of Peoples\u2019 Friendship Medical University","institution_ids":["https://openalex.org/I4210116198"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2195,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.43861177,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"68","issue":"1","first_page":"160","last_page":"168"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11422","display_name":"Burn Injury Management and Outcomes","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11422","display_name":"Burn Injury Management and Outcomes","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/burns","display_name":"burns","score":0.765999972820282},{"id":"https://openalex.org/keywords/multiple-organ-failure","display_name":"multiple organ failure","score":0.9919999837875366},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.7400000095367432},{"id":"https://openalex.org/keywords/free-radicals","display_name":"free radicals","score":0.8389999866485596},{"id":"https://openalex.org/keywords/membrane-damage","display_name":"membrane damage","score":0.6150000095367432},{"id":"https://openalex.org/keywords/mitochondrial-damage","display_name":"mitochondrial damage","score":0.7839999794960022},{"id":"https://openalex.org/keywords/mitochondrial-dna-damage","display_name":"mitochondrial DNA damage","score":0.9100000262260437},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.6420000195503235},{"id":"https://openalex.org/keywords/lipid-transport","display_name":"lipid transport","score":0.777999997138977},{"id":"https://openalex.org/keywords/hormone-imbalance","display_name":"hormonal imbalance","score":0.9819999933242798},{"id":"https://openalex.org/keywords/antioxidants","display_name":"antioxidants","score":0.9369999766349792},{"id":"https://openalex.org/keywords/quinones","display_name":"quinones","score":0.9810000061988831},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.5450000166893005}],"concepts":[{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.647002100944519},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.6053124666213989},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5909332036972046},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.4928617477416992},{"id":"https://openalex.org/C4733338","wikidata":"https://www.wikidata.org/wiki/Q2792936","display_name":"Lipid metabolism","level":2,"score":0.47508397698402405},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.4681810438632965},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.4619719088077545},{"id":"https://openalex.org/C3020296196","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative damage","level":3,"score":0.4491382837295532},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4353013038635254},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.40143731236457825},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37507009506225586},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35085371136665344},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.2964199185371399},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.27501583099365234},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.258916974067688},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.23659461736679077},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.18063169717788696}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.31857/s0006302923010180","doi":"https://doi.org/10.31857/s0006302923010180","is_oa":false,"landing_page_url":"https://doi.org/10.31857/s0006302923010180","pdf_url":null,"source":{"id":"https://openalex.org/S184337958","display_name":"\u0411\u0438\u043e\u0444\u0438\u0437\u0438\u043a\u0430","issn_l":"0006-3029","issn":["0006-3029"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319820","host_organization_name":"MAIK Nauka/Interperiodica","host_organization_lineage":["https://openalex.org/P4310319820","https://openalex.org/P4310320267"],"host_organization_lineage_names":["MAIK Nauka/Interperiodica","Pleiades Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"\u0411\u0438\u043e\u0444\u0438\u0437\u0438\u043a\u0430","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":88,"referenced_works":["https://openalex.org/W172604253","https://openalex.org/W1248344820","https://openalex.org/W1548836679","https://openalex.org/W1727067195","https://openalex.org/W1872846668","https://openalex.org/W1922526906","https://openalex.org/W1969628253","https://openalex.org/W1972507229","https://openalex.org/W1973622329","https://openalex.org/W1978300863","https://openalex.org/W1982706976","https://openalex.org/W1990766361","https://openalex.org/W1991041570","https://openalex.org/W1994543083","https://openalex.org/W1996728254","https://openalex.org/W2000926951","https://openalex.org/W2003945169","https://openalex.org/W2003962839","https://openalex.org/W2005756055","https://openalex.org/W2007688418","https://openalex.org/W2007761806","https://openalex.org/W2008283091","https://openalex.org/W2010961118","https://openalex.org/W2011461103","https://openalex.org/W2017692041","https://openalex.org/W2021071018","https://openalex.org/W2022451432","https://openalex.org/W2023359979","https://openalex.org/W2024203884","https://openalex.org/W2026519169","https://openalex.org/W2031111778","https://openalex.org/W2035638871","https://openalex.org/W2047087508","https://openalex.org/W2048295986","https://openalex.org/W2048787555","https://openalex.org/W2051301953","https://openalex.org/W2052093978","https://openalex.org/W2055728317","https://openalex.org/W2057699266","https://openalex.org/W2058614268","https://openalex.org/W2068358887","https://openalex.org/W2072092960","https://openalex.org/W2072801940","https://openalex.org/W2078855480","https://openalex.org/W2080891051","https://openalex.org/W2081458596","https://openalex.org/W2084852217","https://openalex.org/W2086150081","https://openalex.org/W2086327676","https://openalex.org/W2089669276","https://openalex.org/W2096535920","https://openalex.org/W2124178439","https://openalex.org/W2124843142","https://openalex.org/W2147069858","https://openalex.org/W2149357130","https://openalex.org/W2150592608","https://openalex.org/W2161285579","https://openalex.org/W2164965901","https://openalex.org/W2339002837","https://openalex.org/W2421525486","https://openalex.org/W2515820065","https://openalex.org/W2585072200","https://openalex.org/W2606232917","https://openalex.org/W2607257273","https://openalex.org/W2736715081","https://openalex.org/W2737957366","https://openalex.org/W2747197313","https://openalex.org/W2892467853","https://openalex.org/W2896475841","https://openalex.org/W2898524241","https://openalex.org/W2905639200","https://openalex.org/W2909171478","https://openalex.org/W2913004193","https://openalex.org/W2914107133","https://openalex.org/W2922334712","https://openalex.org/W2922389230","https://openalex.org/W2969374276","https://openalex.org/W2974422971","https://openalex.org/W3001616488","https://openalex.org/W3001766503","https://openalex.org/W3013239488","https://openalex.org/W3081359074","https://openalex.org/W3177396154","https://openalex.org/W3200613212","https://openalex.org/W4211234775","https://openalex.org/W4220781529","https://openalex.org/W4283795079","https://openalex.org/W4290592852"],"related_works":["https://openalex.org/W4386106177","https://openalex.org/W3184698927","https://openalex.org/W1234787456","https://openalex.org/W2072761512","https://openalex.org/W1978011501","https://openalex.org/W2506515860","https://openalex.org/W2567052650","https://openalex.org/W7154832765","https://openalex.org/W2018971050","https://openalex.org/W4411212587"],"abstract_inverted_index":{"Despite":[0],"significant":[1],"progress":[2],"in":[3,10,55,82,89,95,101,124,145],"the":[4,18,30,39,48,90,96,136,139,146],"treatment":[5,147],"of":[6,20,29,50,79,92,103,114,119,138,148],"burn":[7,149],"disease,":[8],"mortality":[9],"this":[11],"pathology":[12],"can":[13],"exceed":[14],"50%":[15],"owing":[16],"to":[17,60,134],"development":[19,49],"multiple":[21,51,104],"organ":[22,52,105],"dysfunction":[23,53],"syndrome":[24,54],"when":[25],"more":[26],"than":[27],"30%":[28],"body":[31],"surface":[32],"area":[33],"is":[34,72,130],"affected.":[35],"The":[36],"review":[37],"describes":[38],"most":[40],"important":[41],"molecular":[42],"and":[43,74,85,98,107,142],"biological":[44],"mechanisms":[45],"that":[46],"underlie":[47],"which":[56],"free-radicals":[57],"cause":[58],"damage":[59],"plasma":[61],"membranes,":[62],"mitochondria,":[63],"damaged":[64],"mitochondria":[65],"generate":[66],"other":[67],"free":[68],"radicals,":[69],"mitochondrial":[70],"DNA":[71],"modified":[73],"used":[75],"as":[76,122],"a":[77,131],"trigger":[78],"inflammatory":[80,140],"processes":[81],"peripheral":[83],"organs":[84],"systems.":[86],"Secondary":[87],"changes":[88],"system":[91],"lipid":[93,127],"transport":[94],"blood":[97],"their":[99],"role":[100],"generalization":[102],"failure":[106],"hormonal":[108,143],"imbalance":[109,144],"are":[110],"considered.":[111],"In":[112],"view":[113],"pathogenic":[115],"metabolic":[116],"shifts,":[117],"use":[118],"antioxidants":[120],"(such":[121],"quinones)":[123],"combination":[125],"with":[126],"metabolism":[128],"modulators":[129],"reasonable":[132],"strategy":[133],"reduce":[135],"activity":[137],"process":[141],"disease.":[150]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2024-04-13T00:00:00"}