{"id":"https://openalex.org/W4394744346","doi":null,"title":"Highlights From the ACG Guidelines for Acute Liver Failure.","display_name":"Highlights From the ACG Guidelines for Acute Liver Failure.","publication_year":2024,"publication_date":"2024-01-01","ids":{"openalex":"https://openalex.org/W4394744346","pmid":"https://pubmed.ncbi.nlm.nih.gov/38405050","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10885416"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:10885416","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10885416","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10885416/pdf/GH_20_1_61.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterol Hepatol (N Y)","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10885416/pdf/GH_20_1_61.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038062344","display_name":"Alexandra Shingina","orcid":"https://orcid.org/0000-0002-7802-5975","observed_orcids":["https://orcid.org/0000-0002-7802-5975"]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Alexandra Shingina","raw_affiliation_strings":["Associate Professor of Medicine Vanderbilt University Medical Center Nashville, Tennessee"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Associate Professor of Medicine Vanderbilt University Medical Center Nashville, Tennessee","institution_ids":["https://openalex.org/I901861585"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5038062344"],"corresponding_institution_ids":["https://openalex.org/I901861585"],"apc_list":null,"apc_paid":null,"fwci":0.5334,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.62357014,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"20","issue":"1","first_page":"61","last_page":"63"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.005799999926239252,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-liver-failure","display_name":"acute liver failure","score":1.0},{"id":"https://openalex.org/keywords/american-college-of-gastroenterology","display_name":"American College of Gastroenterology","score":0.8539999723434448},{"id":"https://openalex.org/keywords/hepatic-encephalopathy","display_name":"hepatic encephalopathy","score":0.9190000295639038},{"id":"https://openalex.org/keywords/international-normalized-ratio","display_name":"international normalized ratio","score":0.8100000023841858},{"id":"https://openalex.org/keywords/liver-dysfunction","display_name":"liver dysfunction","score":0.7720000147819519},{"id":"https://openalex.org/keywords/acute-liver-injury","display_name":"acute liver injury","score":0.7400000095367432},{"id":"https://openalex.org/keywords/disease-definition","display_name":"disease definition","score":0.4099999964237213}],"concepts":[{"id":"https://openalex.org/C2994427840","wikidata":"https://www.wikidata.org/wiki/Q970208","display_name":"Liver failure","level":2,"score":0.7191612124443054},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45138365030288696},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4374653398990631},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3197941780090332}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:10885416","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10885416","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10885416/pdf/GH_20_1_61.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterol Hepatol (N Y)","raw_type":"Text"},{"id":"pmid:38405050","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38405050","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology & hepatology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:10885416","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10885416","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10885416/pdf/GH_20_1_61.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterol Hepatol (N Y)","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4394744346.pdf","grobid_xml":"https://content.openalex.org/works/W4394744346.grobid-xml"},"referenced_works_count":5,"referenced_works":["https://openalex.org/W2193210707","https://openalex.org/W3164212931","https://openalex.org/W4211175126","https://openalex.org/W4220702109","https://openalex.org/W4382345302"],"related_works":["https://openalex.org/W4226326149","https://openalex.org/W4382345302","https://openalex.org/W2570845590","https://openalex.org/W4205571696","https://openalex.org/W4384639550","https://openalex.org/W4226167771","https://openalex.org/W4238668454","https://openalex.org/W4248299964","https://openalex.org/W4386909880","https://openalex.org/W2043949310"],"abstract_inverted_index":{"D":[0],"i":[1],"s":[2,5],"e":[3],"a":[4,38,54,206,216],"eHighlights":[6],"From":[7],"the":[8,42,46,58,73,81,89,99,118,123,135,144,149,162,184,191],"ACG":[9,145],"Guidelines":[10],"for":[11,21,45],"Acute":[12],"Liver":[13,49],"Failure":[14],"G&H":[15,141],"Why":[16],"were":[17,115],"guidelines":[18,29,114],"recently":[19],"released":[20,36],"acute":[22,31,84,111,152,158,165,212],"liver":[23,32,85,112,153,159,166,192,213,220],"failure?":[24],"ASThe":[25],"previous":[26],"North":[27],"American":[28,43,90,124],"on":[30,61],"failure":[33,113,160,214],"had":[34],"been":[35,203],"over":[37],"decade":[39],"ago":[40],"from":[41,88,215],"Association":[44],"Study":[47],"of":[48,83,92,101,122,126,138,151,157,164,179,186,190,218],"Diseases,":[50],"so":[51],"there":[52],"was":[53,67,130],"need":[55],"to":[56,68,80,108,133,143,210],"review":[57],"updated":[59],"literature":[60],"this":[62,139],"disease":[63],"since":[64],"then.The":[65],"goal":[66],"incorporate":[69],"recent":[70],"advances":[71],"in":[72,117],"medical":[74],"field":[75],"and":[76,105,128,183],"how":[77],"they":[78],"relate":[79],"management":[82],"failure.A":[86],"group":[87],"College":[91],"Gastroenterology":[93],"(ACG)":[94],"reviewed":[95],"scientific":[96],"evidence":[97],"using":[98],"Grading":[100],"Recommendations,":[102],"Assessment,":[103],"Development":[104],"Evaluation":[106],"process":[107],"develop":[109],"recommendations.These":[110],"published":[116],"July":[119],"2023":[120],"issue":[121],"Journal":[125],"Gastroenterology,":[127],"I":[129],"lucky":[131],"enough":[132],"be":[134],"first":[136],"author":[137],"publication.":[140],"According":[142],"guidelines,":[146],"what":[147],"is":[148,195],"definition":[150,156],"failure?AS":[154],"The":[155],"includes":[161],"development":[163,185,194],"injury":[167,193],"that":[168],"produces":[169],"hepatic":[170,187],"dysfunction,":[171],"usually":[172],"defined":[173],"by":[174],"an":[175],"international":[176],"normalized":[177],"ratio":[178],"greater":[180],"than":[181,199],"1.5":[182],"encephalopathy.The":[188],"timeline":[189],"important,":[196],"as":[197,205],"less":[198],"26":[200],"weeks":[201],"has":[202],"proposed":[204],"cutoff,":[207],"which":[208],"helps":[209],"differentiate":[211],"number":[217],"other":[219],"diseases.":[221]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2024-04-13T00:00:00"}