{"id":"https://openalex.org/W4394740958","doi":"https://doi.org/10.15036/arerugi.73.34","title":"[A CASE OF CLINICALLY AMYOPATHIC DERMAMYOSITIS WITH INTERSTITIAL LUNG DISEASE SHOWING TWO DETERIORATIONS IN 4 YEARS].","display_name":"[A CASE OF CLINICALLY AMYOPATHIC DERMAMYOSITIS WITH INTERSTITIAL LUNG DISEASE SHOWING TWO DETERIORATIONS IN 4 YEARS].","publication_year":2024,"publication_date":"2024-01-01","ids":{"openalex":"https://openalex.org/W4394740958","doi":"https://doi.org/10.15036/arerugi.73.34","pmid":"https://pubmed.ncbi.nlm.nih.gov/38403699"},"language":"ja","primary_location":{"id":"pmid:38403699","doi":"https://doi.org/10.15036/arerugi.73.34","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38403699","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arerugi = [Allergy]","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101450913","display_name":"Takashi Yamane","orcid":"https://orcid.org/0000-0001-5053-5933","observed_orcids":["https://orcid.org/0000-0001-5053-5933"]},"institutions":[{"id":"https://openalex.org/I4405256591","display_name":"Kochi Health Sciences Center","ror":"https://ror.org/04b3jbx04","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405256591"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takashi Yamane","raw_affiliation_strings":["Department of Respiratory Medicine, Kochi Health Sciences Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Kochi Health Sciences Center","institution_ids":["https://openalex.org/I4405256591"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082861428","display_name":"Tomoyuki Urata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405256591","display_name":"Kochi Health Sciences Center","ror":"https://ror.org/04b3jbx04","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4405256591"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoyuki Urata","raw_affiliation_strings":["Department of Respiratory Medicine, Kochi Health Sciences Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Kochi Health Sciences Center","institution_ids":["https://openalex.org/I4405256591"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4405256591"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.06074661,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"73","issue":"1","first_page":"34","last_page":"39"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11724","display_name":"Inflammatory Myopathies and Dermatomyositis","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11724","display_name":"Inflammatory Myopathies and Dermatomyositis","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11271","display_name":"Myasthenia Gravis and Thymoma","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interstitial-lung-disease","display_name":"interstitial lung disease","score":0.9980000257492065},{"id":"https://openalex.org/keywords/anti-mda5-antibody","display_name":"anti-MDA5 antibodies","score":0.9810000061988831},{"id":"https://openalex.org/keywords/intravenous-cyclophosphamide","display_name":"intravenous cyclophosphamide","score":0.9070000052452087},{"id":"https://openalex.org/keywords/steroid-pulse-therapy","display_name":"steroid pulse therapy","score":0.9729999899864197},{"id":"https://openalex.org/keywords/calcineurin-inhibitors","display_name":"calcineurin inhibitors","score":0.9350000023841858},{"id":"https://openalex.org/keywords/therapeutic-plasma-exchange","display_name":"plasma exchange","score":0.871999979019165},{"id":"https://openalex.org/keywords/kl-6","display_name":"KL-6","score":0.7829999923706055},{"id":"https://openalex.org/keywords/disease-deterioration","display_name":"disease deterioration","score":0.5889999866485596},{"id":"https://openalex.org/keywords/acute-respiratory-failure","display_name":"acute respiratory failure","score":0.8999999761581421},{"id":"https://openalex.org/keywords/autoimmune-myositis","display_name":"autoimmune myositis","score":0.5199999809265137}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7886775732040405},{"id":"https://openalex.org/C2777543607","wikidata":"https://www.wikidata.org/wiki/Q1153419","display_name":"Interstitial lung disease","level":3,"score":0.6845161318778992},{"id":"https://openalex.org/C2780401358","wikidata":"https://www.wikidata.org/wiki/Q422252","display_name":"Dexamethasone","level":2,"score":0.586930513381958},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.557676374912262},{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.5574091672897339},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.5301966071128845},{"id":"https://openalex.org/C2776888751","wikidata":"https://www.wikidata.org/wiki/Q767485","display_name":"Respiratory failure","level":2,"score":0.5247367024421692},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.5006492137908936},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.4239211976528168},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.36665529012680054},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.14941886067390442}],"mesh":[{"descriptor_ui":"D000072640","descriptor_name":"Interferon-Induced Helicase, IFIH1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001323","descriptor_name":"Autoantibodies","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D003520","descriptor_name":"Cyclophosphamide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D003882","descriptor_name":"Dermatomyositis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D003882","descriptor_name":"Dermatomyositis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D003882","descriptor_name":"Dermatomyositis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013256","descriptor_name":"Steroids","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":1,"locations":[{"id":"pmid:38403699","doi":"https://doi.org/10.15036/arerugi.73.34","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38403699","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arerugi = [Allergy]","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2789986814","https://openalex.org/W4200296183","https://openalex.org/W3081328361","https://openalex.org/W3092834668","https://openalex.org/W4205519857","https://openalex.org/W2980602607","https://openalex.org/W3010745710","https://openalex.org/W2172230145","https://openalex.org/W2741942947","https://openalex.org/W2064439700"],"abstract_inverted_index":{"We":[0],"report":[1],"the":[2,65,87,108,112,153],"case":[3,160],"of":[4,27,68,75,84,90,115,139],"a":[5,43,149,156],"45-year-old":[6],"man":[7],"who":[8],"was":[9,40,145],"diagnosed":[10],"with":[11,23,42,126,174],"clinically":[12],"amyopathic":[13],"dermamyositis":[14],"(CADM)":[15],"and":[16,29,52,79,92,96,104,130,164],"interstitial":[17],"lung":[18],"disease":[19],"(ILD)":[20],"after":[21,107],"presenting":[22],"skin":[24],"lesions":[25],"typical":[26],"CADM":[28,173],"testing":[30],"positive":[31],"for":[32,155,172],"anti-Melanoma":[33],"Diferentiation-Associated":[34],"gene":[35],"5":[36],"(anti-MDA5)":[37],"anti-bodies.":[38],"He":[39],"treated":[41,124],"regimen":[44],"including":[45],"steroid":[46,76,127],"pulse":[47,77,128],"therapy,":[48,86],"intravenous":[49],"cyclophosphamide":[50],"(IVCY),":[51],"calcineurin":[53],"Inhibitor":[54],"drug,":[55],"which":[56,147],"initially":[57],"improved":[58],"his":[59,69,116],"ILD.":[60,175],"However,":[61],"three":[62],"months":[63,106],"post-treatment,":[64],"first":[66,109],"deterioration":[67,114],"conditions":[70,117],"occurred,":[71,118],"necessitating":[72],"further":[73],"administration":[74],"therapy":[78,129],"IVCY.":[80,131],"After":[81],"eight":[82],"cycles":[83],"IVCY":[85,163],"serum":[88],"levels":[89],"KL-6":[91],"anti-MDA5":[93],"antibodies":[94],"decreased,":[95],"reaching":[97],"their":[98],"lowest":[99],"values.":[100],"Nevertheless,":[101],"two":[102],"years":[103],"six":[105],"observed":[110],"deterioration,":[111],"second":[113],"leading":[119],"to":[120],"acute":[121],"respiratory":[122,140],"failure,":[123,141],"again":[125],"This":[132,159],"treatment":[133],"did":[134],"not":[135],"result":[136],"in":[137],"improvement":[138],"therefore":[142],"plasma":[143,165],"exchange":[144,166],"attempted,":[146],"demonstrated":[148],"beneficial":[150],"effect":[151],"on":[152],"ILD":[154],"short":[157],"time.":[158],"suggests":[161],"that":[162],"might":[167],"be":[168],"effective":[169],"therapeutic":[170],"options":[171]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-04-13T00:00:00"}