{"id":"https://openalex.org/W4394716202","doi":"https://doi.org/10.3390/biomedicines12040843","title":"Osteoporosis, Osteoarthritis, and Subchondral Insufficiency Fracture: Recent Insights","display_name":"Osteoporosis, Osteoarthritis, and Subchondral Insufficiency Fracture: Recent Insights","publication_year":2024,"publication_date":"2024-04-11","ids":{"openalex":"https://openalex.org/W4394716202","doi":"https://doi.org/10.3390/biomedicines12040843","pmid":"https://pubmed.ncbi.nlm.nih.gov/38672197","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11048726"},"language":"en","primary_location":{"id":"doi:10.3390/biomedicines12040843","doi":"https://doi.org/10.3390/biomedicines12040843","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biomedicines12040843","pdf_url":"https://www.mdpi.com/2227-9059/12/4/843/pdf?version=1712821181","source":{"id":"https://openalex.org/S2737005842","display_name":"Biomedicines","issn_l":"2227-9059","issn":["2227-9059"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2227-9059/12/4/843/pdf?version=1712821181","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039680453","display_name":"Shunichi Yokota","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shunichi Yokota","raw_affiliation_strings":["Department of Orthopedic Surgery, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedic Surgery, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045160249","display_name":"Hotaka Ishizu","orcid":"https://orcid.org/0000-0002-0669-1960","observed_orcids":["https://orcid.org/0000-0002-0669-1960"]},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hotaka Ishizu","raw_affiliation_strings":["Department of Orthopedic Surgery, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedic Surgery, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091359512","display_name":"Takuji Miyazaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takuji Miyazaki","raw_affiliation_strings":["Department of Orthopedic Surgery, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedic Surgery, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101655602","display_name":"Daisuke Takahashi","orcid":"https://orcid.org/0000-0003-4740-3643","observed_orcids":["https://orcid.org/0000-0003-4740-3643"]},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Daisuke Takahashi","raw_affiliation_strings":["Department of Orthopedic Surgery, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedic Surgery, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027654739","display_name":"Norimasa Iwasaki","orcid":"https://orcid.org/0000-0002-5496-4046","observed_orcids":["https://orcid.org/0000-0002-5496-4046"]},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Norimasa Iwasaki","raw_affiliation_strings":["Department of Orthopedic Surgery, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan"],"raw_orcid":"https://orcid.org/0000-0002-5496-4046","affiliations":[{"raw_affiliation_string":"Department of Orthopedic Surgery, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016807224","display_name":"Tomohiro Shimizu","orcid":"https://orcid.org/0000-0001-6760-3066","observed_orcids":["https://orcid.org/0000-0001-6760-3066"]},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Tomohiro Shimizu","raw_affiliation_strings":["Department of Orthopedic Surgery, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan"],"raw_orcid":"https://orcid.org/0000-0001-6760-3066","affiliations":[{"raw_affiliation_string":"Department of Orthopedic Surgery, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan","institution_ids":["https://openalex.org/I205349734"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5016807224"],"corresponding_institution_ids":["https://openalex.org/I205349734"],"apc_list":{"value":2600,"currency":"CHF","value_usd":2955},"apc_paid":{"value":2600,"currency":"CHF","value_usd":2955},"fwci":4.0845,"has_fulltext":true,"cited_by_count":45,"citation_normalized_percentile":{"value":0.96563286,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"12","issue":"4","first_page":"843","last_page":"843"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.6704000234603882,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.6704000234603882,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.2761000096797943,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12209","display_name":"Bone and Joint Diseases","score":0.01600000075995922,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/osteoporosis","display_name":"osteoporosis","score":0.9620000123977661},{"id":"https://openalex.org/keywords/osteoarthritis","display_name":"osteoarthritis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/subchondral-insufficiency-fracture","display_name":"subchondral insufficiency fracture","score":0.9959999918937683},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.7310000061988831},{"id":"https://openalex.org/keywords/knee-osteoarthritis","display_name":"knee osteoarthritis","score":0.8510000109672546},{"id":"https://openalex.org/keywords/hip-osteoarthritis","display_name":"hip osteoarthritis","score":1.0},{"id":"https://openalex.org/keywords/fracture-prevention","display_name":"fracture prevention","score":0.746999979019165},{"id":"https://openalex.org/keywords/fracture-liaison-service","display_name":"fracture liaison service","score":0.7889999747276306},{"id":"https://openalex.org/keywords/osteophytes","display_name":"osteophytes","score":0.6880000233650208},{"id":"https://openalex.org/keywords/population-aging","display_name":"population aging","score":0.6620000004768372}],"concepts":[{"id":"https://openalex.org/C2911105243","wikidata":"https://www.wikidata.org/wiki/Q1753467","display_name":"Insufficiency fracture","level":3,"score":0.8709233999252319},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8676602840423584},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.8490990996360779},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.8207026720046997},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5129680037498474},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4833368957042694},{"id":"https://openalex.org/C2778818304","wikidata":"https://www.wikidata.org/wiki/Q1819478","display_name":"Rehabilitation","level":2,"score":0.46249130368232727},{"id":"https://openalex.org/C3018615303","wikidata":"https://www.wikidata.org/wiki/Q1801229","display_name":"Subchondral bone","level":5,"score":0.45541974902153015},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.448814332485199},{"id":"https://openalex.org/C170033053","wikidata":"https://www.wikidata.org/wiki/Q952019","display_name":"Bone remodeling","level":2,"score":0.44320595264434814},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42678022384643555},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1610909402370453},{"id":"https://openalex.org/C3020332539","wikidata":"https://www.wikidata.org/wiki/Q2014564","display_name":"Articular cartilage","level":4,"score":0.15386301279067993},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/biomedicines12040843","doi":"https://doi.org/10.3390/biomedicines12040843","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biomedicines12040843","pdf_url":"https://www.mdpi.com/2227-9059/12/4/843/pdf?version=1712821181","source":{"id":"https://openalex.org/S2737005842","display_name":"Biomedicines","issn_l":"2227-9059","issn":["2227-9059"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11048726","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11048726","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11048726/pdf/biomedicines-12-00843.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"Text"},{"id":"pmid:38672197","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38672197","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:8894f87984c04e0586d9a813a58911be","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/8894f87984c04e0586d9a813a58911be","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biomedicines, Vol 12, Iss 4, p 843 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/biomedicines12040843","doi":"https://doi.org/10.3390/biomedicines12040843","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biomedicines12040843","pdf_url":"https://www.mdpi.com/2227-9059/12/4/843/pdf?version=1712821181","source":{"id":"https://openalex.org/S2737005842","display_name":"Biomedicines","issn_l":"2227-9059","issn":["2227-9059"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4394716202.pdf","grobid_xml":"https://content.openalex.org/works/W4394716202.grobid-xml"},"referenced_works_count":221,"referenced_works":["https://openalex.org/W33469614","https://openalex.org/W653895738","https://openalex.org/W1482530281","https://openalex.org/W1513928844","https://openalex.org/W1617437321","https://openalex.org/W1629470773","https://openalex.org/W1722743488","https://openalex.org/W1756473473","https://openalex.org/W1803714799","https://openalex.org/W1897895659","https://openalex.org/W1898628191","https://openalex.org/W1964891491","https://openalex.org/W1965665343","https://openalex.org/W1981612850","https://openalex.org/W1990091043","https://openalex.org/W1991340716","https://openalex.org/W1991767508","https://openalex.org/W1992150054","https://openalex.org/W1993811384","https://openalex.org/W1997689572","https://openalex.org/W1999367282","https://openalex.org/W2000051532","https://openalex.org/W2000105502","https://openalex.org/W2000275839","https://openalex.org/W2001073907","https://openalex.org/W2014186510","https://openalex.org/W2014287109","https://openalex.org/W2023023057","https://openalex.org/W2027918196","https://openalex.org/W2033482258","https://openalex.org/W2038312531","https://openalex.org/W2038923921","https://openalex.org/W2043834774","https://openalex.org/W2046266055","https://openalex.org/W2053338769","https://openalex.org/W2057392204","https://openalex.org/W2057840152","https://openalex.org/W2058628511","https://openalex.org/W2061551318","https://openalex.org/W2066904385","https://openalex.org/W2067877130","https://openalex.org/W2073644585","https://openalex.org/W2082135316","https://openalex.org/W2084210985","https://openalex.org/W2091322730","https://openalex.org/W2092090318","https://openalex.org/W2097691815","https://openalex.org/W2103495251","https://openalex.org/W2103593428","https://openalex.org/W2104005171","https://openalex.org/W2118436551","https://openalex.org/W2121372492","https://openalex.org/W2128639917","https://openalex.org/W2131255032","https://openalex.org/W2135514574","https://openalex.org/W2137401254","https://openalex.org/W2138352154","https://openalex.org/W2146548807","https://openalex.org/W2151672607","https://openalex.org/W2158748006","https://openalex.org/W2159278572","https://openalex.org/W2167026752","https://openalex.org/W2169713907","https://openalex.org/W2225078923","https://openalex.org/W2228258796","https://openalex.org/W2241802231","https://openalex.org/W2252816756","https://openalex.org/W2294281060","https://openalex.org/W2399746166","https://openalex.org/W2487256703","https://openalex.org/W2516341097","https://openalex.org/W2518145139","https://openalex.org/W2522694580","https://openalex.org/W2537265040","https://openalex.org/W2565710416","https://openalex.org/W2572992558","https://openalex.org/W2580163605","https://openalex.org/W2584631665","https://openalex.org/W2597886199","https://openalex.org/W2597986589","https://openalex.org/W2618456251","https://openalex.org/W2747777164","https://openalex.org/W2747795404","https://openalex.org/W2757393190","https://openalex.org/W2759804701","https://openalex.org/W2760619414","https://openalex.org/W2766010052","https://openalex.org/W2768536442","https://openalex.org/W2778056359","https://openalex.org/W2789780110","https://openalex.org/W2790742050","https://openalex.org/W2795797384","https://openalex.org/W2811366709","https://openalex.org/W2891775252","https://openalex.org/W2891874864","https://openalex.org/W2892645102","https://openalex.org/W2895556010","https://openalex.org/W2899288218","https://openalex.org/W2900345397","https://openalex.org/W2900653045","https://openalex.org/W2904398329","https://openalex.org/W2912375617","https://openalex.org/W2912588230","https://openalex.org/W2914867701","https://openalex.org/W2920954998","https://openalex.org/W2925222795","https://openalex.org/W2936303186","https://openalex.org/W2945149264","https://openalex.org/W2951058633","https://openalex.org/W2955521601","https://openalex.org/W2955666772","https://openalex.org/W2961763298","https://openalex.org/W2969105876","https://openalex.org/W2972593257","https://openalex.org/W2980735646","https://openalex.org/W2981896983","https://openalex.org/W2988845547","https://openalex.org/W2989597194","https://openalex.org/W2990021946","https://openalex.org/W2990156865","https://openalex.org/W2993018854","https://openalex.org/W2996282775","https://openalex.org/W3003261771","https://openalex.org/W3005399962","https://openalex.org/W3007382667","https://openalex.org/W3010778930","https://openalex.org/W3014516901","https://openalex.org/W3015073066","https://openalex.org/W3017108661","https://openalex.org/W3017197366","https://openalex.org/W3021887123","https://openalex.org/W3024907164","https://openalex.org/W3025467686","https://openalex.org/W3033704573","https://openalex.org/W3035066983","https://openalex.org/W3035769496","https://openalex.org/W3036962752","https://openalex.org/W3039092055","https://openalex.org/W3042247169","https://openalex.org/W3044769186","https://openalex.org/W3048026114","https://openalex.org/W3071404068","https://openalex.org/W3096429227","https://openalex.org/W3097763475","https://openalex.org/W3100395807","https://openalex.org/W3100670641","https://openalex.org/W3113571667","https://openalex.org/W3113733444","https://openalex.org/W3120251443","https://openalex.org/W3120713430","https://openalex.org/W3124473689","https://openalex.org/W3126388414","https://openalex.org/W3127640869","https://openalex.org/W3140778413","https://openalex.org/W3142485902","https://openalex.org/W3146599428","https://openalex.org/W3155970462","https://openalex.org/W3160790778","https://openalex.org/W3164361154","https://openalex.org/W3184437812","https://openalex.org/W3205127768","https://openalex.org/W3211866979","https://openalex.org/W3215083305","https://openalex.org/W4200246173","https://openalex.org/W4206973190","https://openalex.org/W4211067786","https://openalex.org/W4211221406","https://openalex.org/W4214602215","https://openalex.org/W4214768404","https://openalex.org/W4220992533","https://openalex.org/W4221004795","https://openalex.org/W4225750223","https://openalex.org/W4280639827","https://openalex.org/W4281632271","https://openalex.org/W4281737395","https://openalex.org/W4283073736","https://openalex.org/W4283207453","https://openalex.org/W4283369713","https://openalex.org/W4283808847","https://openalex.org/W4285037557","https://openalex.org/W4289978601","https://openalex.org/W4292602146","https://openalex.org/W4293433781","https://openalex.org/W4293715379","https://openalex.org/W4294610444","https://openalex.org/W4294839779","https://openalex.org/W4296459809","https://openalex.org/W4297023163","https://openalex.org/W4307908380","https://openalex.org/W4310085954","https://openalex.org/W4311495918","https://openalex.org/W4311820944","https://openalex.org/W4311824636","https://openalex.org/W4311909244","https://openalex.org/W4313627723","https://openalex.org/W4319017574","https://openalex.org/W4319080389","https://openalex.org/W4319158062","https://openalex.org/W4319316977","https://openalex.org/W4320490930","https://openalex.org/W4361284867","https://openalex.org/W4362458425","https://openalex.org/W4367186474","https://openalex.org/W4377862202","https://openalex.org/W4378619307","https://openalex.org/W4380742988","https://openalex.org/W4381250812","https://openalex.org/W4383217332","https://openalex.org/W4385564014","https://openalex.org/W4385602202","https://openalex.org/W4386042200","https://openalex.org/W4386170611","https://openalex.org/W4386272557","https://openalex.org/W4386438371","https://openalex.org/W4386997628","https://openalex.org/W4387447875","https://openalex.org/W4388733978","https://openalex.org/W4389050602","https://openalex.org/W4390061314","https://openalex.org/W6776300243","https://openalex.org/W7074150780"],"related_works":["https://openalex.org/W2936571551","https://openalex.org/W2984749910","https://openalex.org/W2091782337","https://openalex.org/W2168347625","https://openalex.org/W4405397939","https://openalex.org/W2068634774","https://openalex.org/W7097596781","https://openalex.org/W4403693395","https://openalex.org/W2029043183","https://openalex.org/W4221039629"],"abstract_inverted_index":{"The":[0,114,136],"increased":[1],"incidence":[2,137],"of":[3,34,54,90,103,138],"osteoarthritis":[4],"(OA),":[5],"particularly":[6],"knee":[7],"and":[8,11,31,64,77,80,88,128,130,159,171],"hip":[9],"OA,":[10,106,158],"osteoporosis":[12],"(OP),":[13],"owing":[14],"to":[15,74,126,134,142],"population":[16,146],"aging,":[17],"have":[18],"escalated":[19],"the":[20,32,60,86],"medical":[21],"expense":[22],"burden.":[23],"Osteoarthritis":[24],"is":[25,81,140],"more":[26,51],"prevalent":[27],"in":[28,93,120],"older":[29],"women,":[30],"involvement":[33],"subchondral":[35,44,91,111],"bone":[36,92,112,116],"fragility":[37,89],"spotlights":[38],"its":[39],"association":[40],"with":[41,83,145,156],"OP.":[42,84],"Notably,":[43],"insufficiency":[45],"fracture":[46,160,166],"(SIF)":[47],"may":[48,99,122],"represent":[49],"a":[50,101],"pronounced":[52],"condition":[53],"OA":[55,63,79,95,104,121],"pathophysiology.":[56],"This":[57],"review":[58],"summarizes":[59],"relationship":[61],"between":[62],"OP,":[65],"incorporating":[66],"recent":[67],"insights":[68],"into":[69],"SIF.":[70],"Progressive":[71],"SIF":[72,98],"leads":[73],"joint":[75],"collapse":[76],"secondary":[78],"associated":[82],"Furthermore,":[85],"thinning":[87],"early-stage":[94,157],"suggest":[96],"that":[97],"be":[100,123],"subtype":[102],"(osteoporosis-related":[105],"OPOA)":[107],"characterized":[108],"by":[109],"significant":[110],"damage.":[113],"high":[115],"mineral":[117],"density":[118],"observed":[119],"overestimated":[124],"due":[125],"osteophytes":[127],"sclerosis":[129],"can":[131],"potentially":[132],"contribute":[133],"OPOA.":[135],"OPOA":[139],"expected":[141],"increase":[143],"along":[144],"aging.":[147],"Therefore,":[148],"prioritizing":[149],"OP":[150],"screening,":[151],"early":[152],"interventions":[153],"for":[154],"patients":[155],"prevention":[161],"measures":[162],"such":[163],"as":[164],"rehabilitation,":[165],"liaison":[167],"services,":[168],"nutritional":[169],"management,":[170],"medication":[172],"guidance":[173],"are":[174],"essential.":[175]},"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":20},{"year":2024,"cited_by_count":10}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-04-12T00:00:00"}