{"id":"https://openalex.org/W4394599656","doi":"https://doi.org/10.1016/j.heliyon.2024.e29459","title":"Phytochemical characterization and multifaceted bioactivity assessment of essential oil from Ptychotis verticillata Duby: Anti-diabetic, anti-tyrosinase, and anti-inflammatory activity","display_name":"Phytochemical characterization and multifaceted bioactivity assessment of essential oil from Ptychotis verticillata Duby: Anti-diabetic, anti-tyrosinase, and anti-inflammatory activity","publication_year":2024,"publication_date":"2024-04-01","ids":{"openalex":"https://openalex.org/W4394599656","doi":"https://doi.org/10.1016/j.heliyon.2024.e29459","pmid":"https://pubmed.ncbi.nlm.nih.gov/38699706","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11063393"},"language":"en","primary_location":{"id":"doi:10.1016/j.heliyon.2024.e29459","doi":"https://doi.org/10.1016/j.heliyon.2024.e29459","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.heliyon.2024.e29459","pdf_url":null,"source":{"id":"https://openalex.org/S2898612692","display_name":"Heliyon","issn_l":"2405-8440","issn":["2405-8440"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","ki-jl-1","norway-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Heliyon","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.heliyon.2024.e29459","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022343449","display_name":"Mohamed Taibi","orcid":"https://orcid.org/0000-0002-5682-3538","observed_orcids":["https://orcid.org/0000-0002-5682-3538"]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]}],"countries":["MA"],"is_corresponding":true,"raw_author_name":"Mohamed Taibi","raw_affiliation_strings":["Centre de L'Oriental des Sciences et Technologies de L'Eau et de L'Environnement (COSTEE), Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco","Laboratoire d'Am\u00e9lioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Facult\u00e9 des Sciences, Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de L'Oriental des Sciences et Technologies de L'Eau et de L'Environnement (COSTEE), Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco","institution_ids":["https://openalex.org/I4210108110"]},{"raw_affiliation_string":"Laboratoire d'Am\u00e9lioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Facult\u00e9 des Sciences, Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco","institution_ids":["https://openalex.org/I4210108110"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009383310","display_name":"Amine Elbouzidi","orcid":"https://orcid.org/0000-0003-0314-8484","observed_orcids":["https://orcid.org/0000-0003-0314-8484"]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]},{"id":"https://openalex.org/I4210139255","display_name":"Euro-Mediterranean University of Fes","ror":"https://ror.org/03s9x8b85","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210139255"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Amine Elbouzidi","raw_affiliation_strings":["Euro-Mediterranean University of Fes (UEMF), Fes, Morocco","Laboratoire d'Am\u00e9lioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Facult\u00e9 des Sciences, Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Euro-Mediterranean University of Fes (UEMF), Fes, Morocco","institution_ids":["https://openalex.org/I4210139255"]},{"raw_affiliation_string":"Laboratoire d'Am\u00e9lioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Facult\u00e9 des Sciences, Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco","institution_ids":["https://openalex.org/I4210108110"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092555217","display_name":"Mounir Haddou","orcid":"https://orcid.org/0009-0007-4366-843X","observed_orcids":["https://orcid.org/0009-0007-4366-843X"]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Mounir Haddou","raw_affiliation_strings":["Centre de L'Oriental des Sciences et Technologies de L'Eau et de L'Environnement (COSTEE), Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco","Laboratoire d'Am\u00e9lioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Facult\u00e9 des Sciences, Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de L'Oriental des Sciences et Technologies de L'Eau et de L'Environnement (COSTEE), Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco","institution_ids":["https://openalex.org/I4210108110"]},{"raw_affiliation_string":"Laboratoire d'Am\u00e9lioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Facult\u00e9 des Sciences, Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco","institution_ids":["https://openalex.org/I4210108110"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000340324","display_name":"Abdellah Baraich","orcid":"https://orcid.org/0000-0002-7483-6738","observed_orcids":["https://orcid.org/0000-0002-7483-6738"]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Abdellah Baraich","raw_affiliation_strings":["Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Boulevard Mohamed VI, B.P. 717, Oujda, 60000, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Boulevard Mohamed VI, B.P. 717, Oujda, 60000, Morocco","institution_ids":["https://openalex.org/I4210108110"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091876854","display_name":"El Hassania Loukili","orcid":"https://orcid.org/0000-0002-5678-1905","observed_orcids":["https://orcid.org/0000-0002-5678-1905"]},"institutions":[{"id":"https://openalex.org/I4210139255","display_name":"Euro-Mediterranean University of Fes","ror":"https://ror.org/03s9x8b85","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210139255"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"El Hassania Loukili","raw_affiliation_strings":["Euro-Mediterranean University of Fes (UEMF), Fes, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Euro-Mediterranean University of Fes (UEMF), Fes, Morocco","institution_ids":["https://openalex.org/I4210139255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058149397","display_name":"Tarik Moubchir","orcid":"https://orcid.org/0000-0002-6754-9618","observed_orcids":["https://orcid.org/0000-0002-6754-9618"]},"institutions":[{"id":"https://openalex.org/I4210119856","display_name":"Universit\u00e9 Sultan Moulay Slimane","ror":"https://ror.org/02m8tb249","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210119856"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Tarik Moubchir","raw_affiliation_strings":["Polyvalent Team in Research and Development, Polydisciplinary Faculty of Beni Mellal (FPBM), University Sultan Moulay Slimane (USMS), Beni Mellal, 23000, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Polyvalent Team in Research and Development, Polydisciplinary Faculty of Beni Mellal (FPBM), University Sultan Moulay Slimane (USMS), Beni Mellal, 23000, Morocco","institution_ids":["https://openalex.org/I4210119856"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059612507","display_name":"Aimad Allali","orcid":"https://orcid.org/0000-0001-6411-9033","observed_orcids":["https://orcid.org/0000-0001-6411-9033","https://orcid.org/0000-0002-2733-9747"]},"institutions":[{"id":"https://openalex.org/I4210094767","display_name":"Instituts Sup\u00e9rieurs des Professions Infirmi\u00e8res et Techniques de Sant\u00e9","ror":"https://ror.org/007h8y788","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210094767"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Aimad Allali","raw_affiliation_strings":["High Institute of Nursing Professions and Health Techniques Annex Taza, Fez, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"High Institute of Nursing Professions and Health Techniques Annex Taza, Fez, Morocco","institution_ids":["https://openalex.org/I4210094767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025940022","display_name":"Amine Khoulati","orcid":"https://orcid.org/0000-0002-3842-4146","observed_orcids":["https://orcid.org/0000-0002-3842-4146"]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Amine khoulati","raw_affiliation_strings":["Facult\u00e9 de M\u00e9decine et de Pharmacie, Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Facult\u00e9 de M\u00e9decine et de Pharmacie, Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco","institution_ids":["https://openalex.org/I4210108110"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024548048","display_name":"Reda Bellaouchi","orcid":"https://orcid.org/0000-0002-3619-4877","observed_orcids":["https://orcid.org/0000-0002-3619-4877"]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Reda Bellaouchi","raw_affiliation_strings":["Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Boulevard Mohamed VI, B.P. 717, Oujda, 60000, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Boulevard Mohamed VI, B.P. 717, Oujda, 60000, Morocco","institution_ids":["https://openalex.org/I4210108110"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080065417","display_name":"Abdeslam Asehraou","orcid":"https://orcid.org/0000-0001-5195-8217","observed_orcids":["https://orcid.org/0000-0001-5195-8217"]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Abdeslam Asehraou","raw_affiliation_strings":["Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Boulevard Mohamed VI, B.P. 717, Oujda, 60000, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Boulevard Mohamed VI, B.P. 717, Oujda, 60000, Morocco","institution_ids":["https://openalex.org/I4210108110"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008886392","display_name":"Mohamed Addi","orcid":"https://orcid.org/0000-0002-3973-6694","observed_orcids":["https://orcid.org/0000-0002-3973-6694"]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Mohamed Addi","raw_affiliation_strings":["Laboratoire d'Am\u00e9lioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Facult\u00e9 des Sciences, Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'Am\u00e9lioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Facult\u00e9 des Sciences, Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco","institution_ids":["https://openalex.org/I4210108110"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066929478","display_name":"Ahmad Mohammad Salamatullah","orcid":"https://orcid.org/0000-0003-1685-1400","observed_orcids":["https://orcid.org/0000-0003-1685-1400"]},"institutions":[{"id":"https://openalex.org/I28022161","display_name":"King Saud University","ror":"https://ror.org/02f81g417","country_code":"SA","type":"education","lineage":["https://openalex.org/I28022161"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Ahmad Mohammad Salamatullah","raw_affiliation_strings":["Department of Food Science & Nutrition, College of Food and Agricultural Sciences, King Saud University, 11 P.O. Box 2460, Riyadh, 11451, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food Science & Nutrition, College of Food and Agricultural Sciences, King Saud University, 11 P.O. Box 2460, Riyadh, 11451, Saudi Arabia","institution_ids":["https://openalex.org/I28022161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021198709","display_name":"Mohammed Bourhia","orcid":"https://orcid.org/0000-0003-3707-8461","observed_orcids":["https://orcid.org/0000-0003-3707-8461"]},"institutions":[{"id":"https://openalex.org/I4210088687","display_name":"Universit\u00e9 Ibn Zohr","ror":"https://ror.org/006sgpv47","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210088687"]}],"countries":["MA"],"is_corresponding":true,"raw_author_name":"Mohammed Bourhia","raw_affiliation_strings":["Laboratory of Biotechnology and Natural Resources Valorization, Faculty of Sciences, Ibn Zohr University, 80060, Agadir, Morocco","Department of Chemistry and Biochemistry, Faculty of Medicine and Pharmacy, Ibn Zohr University, Laayoune 70000, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biotechnology and Natural Resources Valorization, Faculty of Sciences, Ibn Zohr University, 80060, Agadir, Morocco","institution_ids":["https://openalex.org/I4210088687"]},{"raw_affiliation_string":"Department of Chemistry and Biochemistry, Faculty of Medicine and Pharmacy, Ibn Zohr University, Laayoune 70000, Morocco","institution_ids":["https://openalex.org/I4210088687"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054609195","display_name":"Farhan Siddique","orcid":"https://orcid.org/0000-0003-4358-5259","observed_orcids":["https://orcid.org/0000-0003-4358-5259"]},"institutions":[{"id":"https://openalex.org/I102134673","display_name":"Link\u00f6ping University","ror":"https://ror.org/05ynxx418","country_code":"SE","type":"education","lineage":["https://openalex.org/I102134673"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Farhan Siddique","raw_affiliation_strings":["Laboratory of Organic Electronics, Department of Science and Technology, Link\u00f6ping University, SE-60174, Norrk\u00f6ping, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Organic Electronics, Department of Science and Technology, Link\u00f6ping University, SE-60174, Norrk\u00f6ping, Sweden","institution_ids":["https://openalex.org/I102134673"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089009414","display_name":"Bouchra El Guerrouj","orcid":"https://orcid.org/0000-0002-3287-6950","observed_orcids":["https://orcid.org/0000-0002-3287-6950"]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Bouchra El Guerrouj","raw_affiliation_strings":["Centre de L'Oriental des Sciences et Technologies de L'Eau et de L'Environnement (COSTEE), Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco","Laboratoire d'Am\u00e9lioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Facult\u00e9 des Sciences, Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de L'Oriental des Sciences et Technologies de L'Eau et de L'Environnement (COSTEE), Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco","institution_ids":["https://openalex.org/I4210108110"]},{"raw_affiliation_string":"Laboratoire d'Am\u00e9lioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Facult\u00e9 des Sciences, Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco","institution_ids":["https://openalex.org/I4210108110"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049194874","display_name":"Khalid Chaabane","orcid":"https://orcid.org/0000-0003-1940-9888","observed_orcids":["https://orcid.org/0000-0003-1940-9888"]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Khalid Chaabane","raw_affiliation_strings":["Laboratoire d'Am\u00e9lioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Facult\u00e9 des Sciences, Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'Am\u00e9lioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Facult\u00e9 des Sciences, Universit\u00e9 Mohammed Premier, Oujda, 60000, Morocco","institution_ids":["https://openalex.org/I4210108110"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5021198709","https://openalex.org/A5022343449"],"corresponding_institution_ids":["https://openalex.org/I4210088687","https://openalex.org/I4210108110"],"apc_list":{"value":2100,"currency":"USD","value_usd":2100},"apc_paid":{"value":2100,"currency":"USD","value_usd":2100},"fwci":4.0636,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.93377972,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"10","issue":"8","first_page":"e29459","last_page":"e29459"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.9253000020980835,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.9253000020980835,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.04560000076889992,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.01640000008046627,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/essential-oils","display_name":"essential oils","score":0.968999981880188},{"id":"https://openalex.org/keywords/phytochemical-profile","display_name":"phytochemical composition","score":0.8849999904632568},{"id":"https://openalex.org/keywords/antidiabetic-activity","display_name":"antidiabetic activity","score":0.9110000133514404},{"id":"https://openalex.org/keywords/tyrosinase-inhibition","display_name":"tyrosinase inhibition","score":0.9290000200271606},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.9950000047683716},{"id":"https://openalex.org/keywords/alpha-amylase-inhibition","display_name":"\u03b1-amylase inhibition","score":0.8560000061988831},{"id":"https://openalex.org/keywords/xanthine-oxidase-inhibition","display_name":"xanthine oxidase inhibition","score":0.9580000042915344},{"id":"https://openalex.org/keywords/alpha-glucosidase-inhibition","display_name":"\u03b1-glucosidase inhibition","score":1.0},{"id":"https://openalex.org/keywords/lipoxygenase-inhibition","display_name":"lipoxygenase inhibition","score":0.9409999847412109},{"id":"https://openalex.org/keywords/gamma-terpinene","display_name":"\u03b3-terpinene","score":0.902999997138977},{"id":"https://openalex.org/keywords/carvacrol","display_name":"carvacrol","score":0.9990000128746033},{"id":"https://openalex.org/keywords/gout","display_name":"gout","score":0.6380000114440918},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.4830000102519989},{"id":"https://openalex.org/keywords/pigmentary-disorders","display_name":"skin pigmentation disorders","score":0.7639999985694885},{"id":"https://openalex.org/keywords/raw-264-7-macrophages","display_name":"RAW 264.7 macrophages","score":0.8880000114440918},{"id":"https://openalex.org/keywords/lps-induced-inflammation","display_name":"lipopolysaccharide-induced inflammation","score":0.7649999856948853}],"concepts":[{"id":"https://openalex.org/C195475562","wikidata":"https://www.wikidata.org/wiki/Q1639139","display_name":"Phytochemical","level":2,"score":0.9230712652206421},{"id":"https://openalex.org/C2779703632","wikidata":"https://www.wikidata.org/wiki/Q581996","display_name":"Anti-inflammatory","level":2,"score":0.702358603477478},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.7004333734512329},{"id":"https://openalex.org/C2777278459","wikidata":"https://www.wikidata.org/wiki/Q170885","display_name":"Essential oil","level":2,"score":0.67839515209198},{"id":"https://openalex.org/C87554066","wikidata":"https://www.wikidata.org/wiki/Q85942926","display_name":"Tyrosinase","level":3,"score":0.563732385635376},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3922845423221588},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.35259875655174255},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.34249550104141235},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28960925340652466},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.20831429958343506},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14993005990982056},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.05825185775756836}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1016/j.heliyon.2024.e29459","doi":"https://doi.org/10.1016/j.heliyon.2024.e29459","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.heliyon.2024.e29459","pdf_url":null,"source":{"id":"https://openalex.org/S2898612692","display_name":"Heliyon","issn_l":"2405-8440","issn":["2405-8440"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","ki-jl-1","norway-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Heliyon","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11063393","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11063393","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11063393/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Heliyon","raw_type":"Text"},{"id":"pmid:38699706","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38699706","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Heliyon","raw_type":"Journal Article"},{"id":"pmh:oai:DiVA.org:liu-203771","doi":null,"is_oa":true,"landing_page_url":"https://liu.diva-portal.org/smash/get/diva2:1863116/FULLTEXT01","pdf_url":null,"source":{"id":"https://openalex.org/S4306400838","display_name":"DiVA (Linkoping University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102134673","host_organization_name":"Link\u00f6ping University","host_organization_lineage":["https://openalex.org/I102134673"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:43b5475b4f7e43128aa59a1c8095d520","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/43b5475b4f7e43128aa59a1c8095d520","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Heliyon, Vol 10, Iss 8, Pp e29459- (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.heliyon.2024.e29459","doi":"https://doi.org/10.1016/j.heliyon.2024.e29459","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.heliyon.2024.e29459","pdf_url":null,"source":{"id":"https://openalex.org/S2898612692","display_name":"Heliyon","issn_l":"2405-8440","issn":["2405-8440"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","ki-jl-1","norway-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Heliyon","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G937371115","display_name":null,"funder_award_id":"RSP-2024R437","funder_id":"https://openalex.org/F4320321145","funder_display_name":"King Saud University"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321145","display_name":"King Saud University","ror":"https://ror.org/02f81g417"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":74,"referenced_works":["https://openalex.org/W14695072","https://openalex.org/W106483157","https://openalex.org/W125219858","https://openalex.org/W1275577774","https://openalex.org/W1816585441","https://openalex.org/W1829811284","https://openalex.org/W1965969578","https://openalex.org/W1973147085","https://openalex.org/W1974781648","https://openalex.org/W1980524890","https://openalex.org/W1991164404","https://openalex.org/W1996243500","https://openalex.org/W2006170208","https://openalex.org/W2032366844","https://openalex.org/W2054433034","https://openalex.org/W2057363797","https://openalex.org/W2063610712","https://openalex.org/W2064663880","https://openalex.org/W2066301620","https://openalex.org/W2066515408","https://openalex.org/W2081642488","https://openalex.org/W2087429684","https://openalex.org/W2087461602","https://openalex.org/W2128149258","https://openalex.org/W2129387684","https://openalex.org/W2132159544","https://openalex.org/W2133187342","https://openalex.org/W2145135129","https://openalex.org/W2152912193","https://openalex.org/W2245385868","https://openalex.org/W2282595618","https://openalex.org/W2341021278","https://openalex.org/W2550257263","https://openalex.org/W2617433362","https://openalex.org/W2755385181","https://openalex.org/W2759947925","https://openalex.org/W2799699133","https://openalex.org/W2804265426","https://openalex.org/W2886928305","https://openalex.org/W2895613848","https://openalex.org/W2897838749","https://openalex.org/W2913370805","https://openalex.org/W2930535895","https://openalex.org/W2966117331","https://openalex.org/W2980529432","https://openalex.org/W2982570210","https://openalex.org/W2990956911","https://openalex.org/W2997933217","https://openalex.org/W3014860120","https://openalex.org/W3040954058","https://openalex.org/W3045820483","https://openalex.org/W3046973633","https://openalex.org/W3084385586","https://openalex.org/W3087093288","https://openalex.org/W3112360324","https://openalex.org/W3147365024","https://openalex.org/W4220935198","https://openalex.org/W4296350371","https://openalex.org/W4310535726","https://openalex.org/W4312217032","https://openalex.org/W4312788977","https://openalex.org/W4313367383","https://openalex.org/W4315574039","https://openalex.org/W4315628839","https://openalex.org/W4361003191","https://openalex.org/W4363676676","https://openalex.org/W4364360554","https://openalex.org/W4384928808","https://openalex.org/W4385317829","https://openalex.org/W4387055779","https://openalex.org/W4387843938","https://openalex.org/W4389688092","https://openalex.org/W4390654747","https://openalex.org/W4391841846"],"related_works":["https://openalex.org/W4361003191","https://openalex.org/W2015293616","https://openalex.org/W4318613431","https://openalex.org/W4416941162","https://openalex.org/W2063610712","https://openalex.org/W4385830706","https://openalex.org/W4400366978","https://openalex.org/W3032551907","https://openalex.org/W4408741622","https://openalex.org/W3163888214"],"abstract_inverted_index":{"The":[0,122,226],"aim":[1],"of":[2,11,44,98,124,138,181,209,228,244,251,256],"this":[3,229],"study":[4,37,230],"is":[5,131],"to":[6,25,39,77,93,205],"explore":[7],"the":[8,12,36,41,95,125,207,242,248,254],"pharmacological":[9],"properties":[10],"essential":[13],"oil":[14],"derived":[15],"from":[16],"Ptychotis":[17],"verticillata":[18],"Duby":[19],"(PVEO),":[20],"a":[21,51,202,232],"medicinal":[22],"plant":[23],"native":[24],"Morocco,":[26],"focusing":[27],"on":[28,100,238],"its":[29,48,111,118,195],"antidiabetic,":[30,168],"anti-tyrosinase,":[31],"and":[32,46,87,117,145,164,169,186,211,241,261],"anti-inflammatory":[33,96],"effects.":[34],"Additionally,":[35,199],"aims":[38],"characterize":[40],"phytochemical":[42,62,126],"composition":[43],"PVEO":[45,99,130,155,173,200,252],"evaluate":[47,94],"potential":[49,250],"as":[50,108,110,113],"natural":[52,239],"therapeutic":[53,249],"alternative":[54],"for":[55,197,235],"various":[56,220],"health":[57],"conditions.":[58],"To":[59],"achieve":[60],"this,":[61],"analysis":[63,127],"was":[64],"conducted":[65,76],"using":[66],"gas":[67],"chromatography-mass":[68],"spectrometry":[69],"(GC-MS).":[70],"Furthermore,":[71,172],"in":[72,133,150,219,253],"vitro":[73,151],"assessments":[74],"were":[75,90],"investigate":[78],"PVEO's":[79],"antidiabetic":[80],"activity":[81,159],"by":[82,105],"inhibiting":[83],"\u03b1-amylase,":[84,161],"xanthine":[85,162],"oxidase,":[86,163],"\u03b1-glucosidase.":[88],"Tests":[89],"also":[91],"undertaken":[92],"effect":[97],"RAW":[101],"264.7":[102],"cells":[103],"stimulated":[104],"lipopolysaccharide":[106],"(LPS),":[107],"well":[109],"efficacy":[112],"an":[114,179],"anti-tyrosinase":[115,176],"agent":[116],"lipoxygenase":[119,188],"inhibition":[120,189],"activity.":[121],"results":[123],"revealed":[128],"that":[129,154],"rich":[132],"terpene":[134],"compounds,":[135],"with":[136,178],"percentages":[137],"40.35":[139],"%":[140,143,147],"\u03b3-terpinene,":[141],"22.40":[142],"carvacrol,":[144],"19.77":[146],"\u03b2-cymene.":[148],"Moreover,":[149],"evaluations":[152],"demonstrated":[153],"exhibits":[156],"significant":[157,175],"inhibitory":[158],"against":[160],"\u03b1-glucosidase,":[165],"indicating":[166],"promising":[167],"anti-gout":[170],"potential.":[171],"showed":[174],"activity,":[177],"IC50":[180],"27.39":[182],"\u00b1":[183,191],"0.44":[184],"\u03bcg/mL,":[185],"remarkable":[187],"(87.33":[190],"2.6":[192],"%),":[193],"suggesting":[194],"candidacy":[196],"dermatoprotection.":[198],"displayed":[201],"dose-dependent":[203],"capacity":[204],"attenuate":[206],"production":[208],"NO":[210],"PGE":[212],"2":[213],",":[214],"two":[215],"inflammatory":[216],"mediators":[217],"implicated":[218],"pathologies,":[221],"without":[222],"compromising":[223],"cellular":[224],"viability.":[225],"findings":[227],"provide":[231],"solid":[233],"foundation":[234],"future":[236],"research":[237],"therapies":[240],"development":[243],"new":[245],"drugs,":[246],"highlighting":[247],"treatment":[255],"gout,":[257],"diabetes,":[258],"pigmentation":[259],"disorders,":[260],"inflammation.":[262]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":7}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2024-04-10T00:00:00"}
