{"id":"https://openalex.org/W4394548723","doi":"https://doi.org/10.6084/m9.figshare.7386605","title":"Additional file 4: of Pooled extracellular receptor-ligand interaction screening using CRISPR activation","display_name":"Additional file 4: of Pooled extracellular receptor-ligand interaction screening using CRISPR activation","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W4394548723","doi":"https://doi.org/10.6084/m9.figshare.7386605"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/7386605","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_4_of_Pooled_extracellular_receptor-ligand_interaction_screening_using_CRISPR_activation/7386605","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"volume":null,"type":"dataset","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/dataset/Additional_file_4_of_Pooled_extracellular_receptor-ligand_interaction_screening_using_CRISPR_activation/7386605","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072554811","display_name":"Zheng\u2010Shan Chong","orcid":"https://orcid.org/0000-0002-4875-8609","observed_orcids":["https://orcid.org/0000-0002-4875-8609"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zheng-Shan Chong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Ohnishi, Shuhei","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ohnishi, Shuhei","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000202709","display_name":"Kosuke Yusa","orcid":"https://orcid.org/0000-0002-3442-021X","observed_orcids":["https://orcid.org/0000-0002-3442-021X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yusa, Kosuke","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5029330044","display_name":"Gavin James Wright","orcid":"https://orcid.org/0000-0003-0537-0863","observed_orcids":["https://orcid.org/0000-0003-0537-0863"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wright, Gavin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.9092000126838684,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.9092000126838684,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.014000000432133675,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.00559999980032444,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/crispr-activation","display_name":"CRISPR activation","score":0.8299999833106995},{"id":"https://openalex.org/keywords/protein-protein-interaction-screening","display_name":"protein-protein interaction screening","score":0.6909999847412109}],"concepts":[{"id":"https://openalex.org/C98108389","wikidata":"https://www.wikidata.org/wiki/Q412563","display_name":"CRISPR","level":3,"score":0.8702872395515442},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.5354630351066589},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4847416579723358},{"id":"https://openalex.org/C116569031","wikidata":"https://www.wikidata.org/wiki/Q899107","display_name":"Ligand (biochemistry)","level":3,"score":0.42887169122695923},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40014445781707764},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3850634694099426},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3759879171848297},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35842305421829224},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3221758008003235},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10703280568122864}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/7386605","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_4_of_Pooled_extracellular_receptor-ligand_interaction_screening_using_CRISPR_activation/7386605","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.7386605","doi":"https://doi.org/10.6084/m9.figshare.7386605","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.7386605","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.7386605.v1","doi":"https://doi.org/10.6084/m9.figshare.7386605.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.7386605.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/7386605","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_4_of_Pooled_extracellular_receptor-ligand_interaction_screening_using_CRISPR_activation/7386605","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W6977570432","https://openalex.org/W4394537438","https://openalex.org/W6977135904","https://openalex.org/W7156903457","https://openalex.org/W3189387552","https://openalex.org/W4220894577","https://openalex.org/W2803828233","https://openalex.org/W2460103355","https://openalex.org/W2782677866","https://openalex.org/W4311112561"],"abstract_inverted_index":{"A":[0],"spreadsheet":[1],"containing":[2],"all":[3],"the":[4,12,21,28,31,34,39,64,68,74,78,85],"raw":[5],"gRNA":[6,41,52],"read":[7],"counts":[8,43,53],"for":[9,67,82],"each":[10],"of":[11],"screens":[13],"performed":[14],"in":[15,27,33,84],"this":[16],"study.":[17],"The":[18],"gRNAs":[19],"and":[20,30,48,57,73],"gene":[22],"promoter":[23],"targeted":[24],"are":[25],"listed":[26],"rows,":[29],"experiments":[32],"columns:":[35],"\u201cplasmid\u201d":[36],"refers":[37],"to":[38,45,51,63],"lentiviral":[40],"library":[42],"prior":[44],"transformation;":[46],"\u201cd7\u201d":[47],"\u201cd12-transduced\u201d":[49],"refer":[50],"from":[54],"cells":[55],"7":[56],"12":[58],"days":[59],"after":[60],"transduction;":[61],"\u201c8aB_rep\u201d":[62],"three":[65],"replicates":[66],"pooled":[69],"monoclonal":[70],"antibody":[71],"screen;":[72],"remaining":[75],"columns":[76],"list":[77],"protein":[79],"probes":[80],"used":[81],"selection":[83],"screens.":[86],"(XLSX":[87],"5146":[88],"kb)":[89]},"counts_by_year":[],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2024-04-08T00:00:00"}