{"id":"https://openalex.org/W4394425477","doi":"https://doi.org/10.6084/m9.figshare.12173232","title":"In situ RNA sequencing of the juvenile, adult and diseased pancreas","display_name":"In situ RNA sequencing of the juvenile, adult and diseased pancreas","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W4394425477","doi":"https://doi.org/10.6084/m9.figshare.12173232"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/12173232","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/In_situ_RNA_sequencing_of_the_juvenile_adult_and_diseased_pancreas/12173232","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"volume":null,"type":"dataset","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/dataset/In_situ_RNA_sequencing_of_the_juvenile_adult_and_diseased_pancreas/12173232","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Tosti, Luca","orcid":"https://orcid.org/0000-0003-2941-965X","observed_orcids":["https://orcid.org/0000-0003-2941-965X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tosti, Luca","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2941-965X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062511690","display_name":"Yan Hang","orcid":"https://orcid.org/0000-0002-5166-2480","observed_orcids":["https://orcid.org/0000-0002-5166-2480"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hang, Yan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014779997","display_name":"Olivia Debnath","orcid":"https://orcid.org/0009-0009-2845-055X","observed_orcids":["https://orcid.org/0009-0009-2845-055X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Debnath, Olivia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058200006","display_name":"Sebastian Tiesmeyer","orcid":"https://orcid.org/0000-0002-0492-1523","observed_orcids":["https://orcid.org/0000-0002-0492-1523"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tiesmeyer, Sebastian","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014938888","display_name":"Timo B. Trefzer","orcid":"https://orcid.org/0000-0003-2031-7470","observed_orcids":["https://orcid.org/0000-0003-2031-7470"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Trefzer, Timo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001164379","display_name":"Katja Steiger","orcid":"https://orcid.org/0000-0002-7269-5433","observed_orcids":["https://orcid.org/0000-0002-7269-5433"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Steiger, Katja","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071917764","display_name":"Foo Wei Ten","orcid":"https://orcid.org/0000-0003-0839-6815","observed_orcids":["https://orcid.org/0000-0003-0839-6815"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Foo Wei Ten","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020646210","display_name":"Soeren Lukassen","orcid":"https://orcid.org/0000-0001-7045-6327","observed_orcids":["https://orcid.org/0000-0001-7045-6327"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Soeren Lukassen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020765592","display_name":"Simone Ballke","orcid":"https://orcid.org/0000-0001-6586-2099","observed_orcids":["https://orcid.org/0000-0001-6586-2099"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ballke, Simone","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110100653","display_name":"Anja A. Kuehl","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kuehl, Anja A","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009949146","display_name":"Simone Spieckermann","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Spieckermann, Simone","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053200897","display_name":"Rita Bottino","orcid":"https://orcid.org/0000-0003-1540-2996","observed_orcids":["https://orcid.org/0000-0003-1540-2996"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bottino, Rita","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050689432","display_name":"Naveed Ishaque","orcid":"https://orcid.org/0000-0002-8426-901X","observed_orcids":["https://orcid.org/0000-0002-8426-901X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ishaque, Naveed","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018744564","display_name":"Wilko Weichert","orcid":"https://orcid.org/0000-0001-6139-8372","observed_orcids":["https://orcid.org/0000-0001-6139-8372"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Weichert, Wilko","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039399292","display_name":"Seung K. Kim","orcid":"https://orcid.org/0000-0001-6135-7810","observed_orcids":["https://orcid.org/0000-0001-6135-7810"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kim, Seung K.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044191947","display_name":"Roland Eils","orcid":"https://orcid.org/0000-0002-0034-4036","observed_orcids":["https://orcid.org/0000-0002-0034-4036"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eils, Roland","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5072661843","display_name":"Christian Conrad","orcid":"https://orcid.org/0000-0001-7036-342X","observed_orcids":["https://orcid.org/0000-0001-7036-342X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Conrad, Christian","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.8169000148773193,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.8169000148773193,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.11810000240802765,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.03229999914765358,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-pancreas","display_name":"human pancreas","score":0.9179999828338623},{"id":"https://openalex.org/keywords/pancreatic-islets","display_name":"pancreatic islets","score":0.6320000290870667},{"id":"https://openalex.org/keywords/adult-pancreas","display_name":"adult pancreas","score":0.9150000214576721},{"id":"https://openalex.org/keywords/pancreatic-diseases","display_name":"pancreatic diseases","score":0.7250000238418579},{"id":"https://openalex.org/keywords/gene-expression-mapping","display_name":"gene expression mapping","score":0.5130000114440918},{"id":"https://openalex.org/keywords/dapi-staining","display_name":"DAPI staining","score":0.7110000252723694}],"concepts":[{"id":"https://openalex.org/C115961737","wikidata":"https://www.wikidata.org/wiki/Q1516282","display_name":"Juvenile","level":2,"score":0.7524823546409607},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5609768629074097},{"id":"https://openalex.org/C2777822432","wikidata":"https://www.wikidata.org/wiki/Q216681","display_name":"In situ","level":2,"score":0.5067639946937561},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4870605766773224},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.47863712906837463},{"id":"https://openalex.org/C2778764654","wikidata":"https://www.wikidata.org/wiki/Q9618","display_name":"Pancreas","level":2,"score":0.47224897146224976},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.29383569955825806},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1295512616634369},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10733333230018616},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.08879989385604858},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/12173232","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/In_situ_RNA_sequencing_of_the_juvenile_adult_and_diseased_pancreas/12173232","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.12173232","doi":"https://doi.org/10.6084/m9.figshare.12173232","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.12173232","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.12173232.v1","doi":"https://doi.org/10.6084/m9.figshare.12173232.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.12173232.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/12173232","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/In_situ_RNA_sequencing_of_the_juvenile_adult_and_diseased_pancreas/12173232","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.504800021648407,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3106000943","https://openalex.org/W6902135843","https://openalex.org/W7134953515","https://openalex.org/W4285663911","https://openalex.org/W6893979152","https://openalex.org/W7076335809","https://openalex.org/W7087100051","https://openalex.org/W7128355633","https://openalex.org/W2090920934","https://openalex.org/W7203768783"],"abstract_inverted_index":{"This":[0],"dataset":[1],"contains":[2],"the":[3,31,36,39,43,51,65],"X,Y":[4],"coordinates":[5],"of":[6,35,42,50,64],"each":[7],"mRNA":[8],"spot":[9],"detected":[10],"via":[11],"in":[12,54],"situ":[13],"sequencing":[14],"for":[15],"five":[16,66],"different":[17],"human":[18],"pancreatic":[19],"samples":[20],"(preprocessing":[21],"performed":[22],"by":[23],"Cartana).":[24],"We":[25,45],"include":[26,47,59],"a":[27,48],"metadata":[28],"table":[29],"specifying":[30],"sex":[32],"and":[33,38],"age":[34],"donor":[37],"pancreas":[40],"location":[41],"tissue.":[44],"also":[46],"list":[49],"genes":[52],"targeted":[53],"these":[55],"experiments.":[56],"Lastly,":[57],"we":[58],"nuclear":[60],"staining":[61],"(DAPI)":[62],"images":[63],"samples.":[67]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2024-04-08T00:00:00"}