{"id":"https://openalex.org/W4394413009","doi":"https://doi.org/10.6084/m9.figshare.13498082","title":"Additional file 1 of A pan-kidney cancer study identifies subtype specific perturbations on pathways with potential drivers in renal cell carcinoma","display_name":"Additional file 1 of A pan-kidney cancer study identifies subtype specific perturbations on pathways with potential drivers in renal cell carcinoma","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W4394413009","doi":"https://doi.org/10.6084/m9.figshare.13498082"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/13498082","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_1_of_A_pan-kidney_cancer_study_identifies_subtype_specific_perturbations_on_pathways_with_potential_drivers_in_renal_cell_carcinoma/13498082","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"volume":null,"type":"dataset","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/dataset/Additional_file_1_of_A_pan-kidney_cancer_study_identifies_subtype_specific_perturbations_on_pathways_with_potential_drivers_in_renal_cell_carcinoma/13498082","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100707495","display_name":"Xiaohui Zhan","orcid":"https://orcid.org/0000-0003-1326-6601","observed_orcids":["https://orcid.org/0000-0003-1326-6601"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]},{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Zhan, Xiaohui","raw_affiliation_strings":["Chongqing Medical University","Indiana University \u2013 Purdue University Indianapolis","Shenzhen University"],"raw_orcid":"https://orcid.org/0000-0003-1326-6601","affiliations":[{"raw_affiliation_string":"Chongqing Medical University","institution_ids":["https://openalex.org/I87780372"]},{"raw_affiliation_string":"Indiana University \u2013 Purdue University Indianapolis","institution_ids":["https://openalex.org/I55769427"]},{"raw_affiliation_string":"Shenzhen University","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045253111","display_name":"Yusong Liu","orcid":"https://orcid.org/0000-0003-4950-6304","observed_orcids":["https://orcid.org/0000-0003-4950-6304"]},"institutions":[{"id":"https://openalex.org/I151727225","display_name":"Harbin Engineering University","ror":"https://ror.org/03x80pn82","country_code":"CN","type":"education","lineage":["https://openalex.org/I151727225"]},{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Liu, Yusong","raw_affiliation_strings":["Indiana University \u2013 Purdue University Indianapolis","Harbin Engineering University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana University \u2013 Purdue University Indianapolis","institution_ids":["https://openalex.org/I55769427"]},{"raw_affiliation_string":"Harbin Engineering University","institution_ids":["https://openalex.org/I151727225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041863346","display_name":"Christina Y. Yu","orcid":"https://orcid.org/0000-0002-4165-6781","observed_orcids":["https://orcid.org/0000-0002-4165-6781"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]},{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yu, Christina Y.","raw_affiliation_strings":["Indiana University \u2013 Purdue University Indianapolis","The Ohio State University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana University \u2013 Purdue University Indianapolis","institution_ids":["https://openalex.org/I55769427"]},{"raw_affiliation_string":"The Ohio State University","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046543349","display_name":"Tianfu Wang","orcid":"https://orcid.org/0000-0002-1248-1214","observed_orcids":["https://orcid.org/0000-0002-1248-1214"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wang, Tian-Fu","raw_affiliation_strings":["Shenzhen University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen University","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100436821","display_name":"Jie Zhang","orcid":"https://orcid.org/0000-0001-6939-7905","observed_orcids":["https://orcid.org/0000-0001-6939-7905"]},"institutions":[{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhang, Jie","raw_affiliation_strings":["Indiana University \u2013 Purdue University Indianapolis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana University \u2013 Purdue University Indianapolis","institution_ids":["https://openalex.org/I55769427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065374358","display_name":"Dong Ni","orcid":"https://orcid.org/0000-0002-9146-6003","observed_orcids":["https://orcid.org/0000-0002-9146-6003"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ni, Dong","raw_affiliation_strings":["Shenzhen University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen University","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057366605","display_name":"Kun Huang","orcid":"https://orcid.org/0000-0002-8530-370X","observed_orcids":["https://orcid.org/0000-0002-8530-370X","https://orcid.org/0000-0001-8550-4571","https://orcid.org/0000-0003-0071-7522","https://orcid.org/0000-0003-0797-8338","https://orcid.org/0000-0002-9400-9799"]},"institutions":[{"id":"https://openalex.org/I1324682000","display_name":"Regenstrief Institute","ror":"https://ror.org/05f2ywb48","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1324682000"]},{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Huang, Kun","raw_affiliation_strings":["Indiana University \u2013 Purdue University Indianapolis","Regenstrief Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana University \u2013 Purdue University Indianapolis","institution_ids":["https://openalex.org/I55769427"]},{"raw_affiliation_string":"Regenstrief Institute","institution_ids":["https://openalex.org/I1324682000"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10449","display_name":"Renal cell carcinoma treatment","score":0.9829000234603882,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10449","display_name":"Renal cell carcinoma treatment","score":0.9829000234603882,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.008799999952316284,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11297","display_name":"Ferroptosis and cancer prognosis","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/renal-cell-carcinoma","display_name":"renal cell carcinoma","score":0.9589999914169312},{"id":"https://openalex.org/keywords/kidney-cancer","display_name":"kidney cancer","score":0.9070000052452087},{"id":"https://openalex.org/keywords/pathway-perturbation","display_name":"pathway perturbation","score":0.6740000247955322},{"id":"https://openalex.org/keywords/differentially-expressed-genes","display_name":"differentially expressed genes","score":0.9150000214576721},{"id":"https://openalex.org/keywords/tumor-subtypes","display_name":"tumor subtypes","score":0.7620000243186951},{"id":"https://openalex.org/keywords/driver-genes","display_name":"driver genes","score":0.5619999766349792}],"concepts":[{"id":"https://openalex.org/C2777472916","wikidata":"https://www.wikidata.org/wiki/Q1164529","display_name":"Renal cell carcinoma","level":2,"score":0.6711487770080566},{"id":"https://openalex.org/C2781068499","wikidata":"https://www.wikidata.org/wiki/Q3242950","display_name":"Kidney cancer","level":3,"score":0.5838750004768372},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.4764956831932068},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.464793860912323},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4550155699253082},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4349935054779053},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4016312062740326},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38967716693878174},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35781973600387573},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.32861465215682983}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/13498082","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_1_of_A_pan-kidney_cancer_study_identifies_subtype_specific_perturbations_on_pathways_with_potential_drivers_in_renal_cell_carcinoma/13498082","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.13498082","doi":"https://doi.org/10.6084/m9.figshare.13498082","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.13498082","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.13498082.v1","doi":"https://doi.org/10.6084/m9.figshare.13498082.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.13498082.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/13498082","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_1_of_A_pan-kidney_cancer_study_identifies_subtype_specific_perturbations_on_pathways_with_potential_drivers_in_renal_cell_carcinoma/13498082","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1966628628","https://openalex.org/W1969963445","https://openalex.org/W1995105931","https://openalex.org/W2010991736","https://openalex.org/W2021793290","https://openalex.org/W2048422848","https://openalex.org/W2053889157","https://openalex.org/W2081087726","https://openalex.org/W2101549029","https://openalex.org/W2111867681","https://openalex.org/W2133838032","https://openalex.org/W2135124600","https://openalex.org/W2138150495","https://openalex.org/W2145293725","https://openalex.org/W2150107812","https://openalex.org/W2153238348","https://openalex.org/W2162143298","https://openalex.org/W2164542609","https://openalex.org/W2167778120","https://openalex.org/W2179438025","https://openalex.org/W2288944226","https://openalex.org/W2335012284","https://openalex.org/W2528569964","https://openalex.org/W2626761578","https://openalex.org/W2796207353","https://openalex.org/W2802731336","https://openalex.org/W2889439536","https://openalex.org/W2982584140","https://openalex.org/W3029198789"],"related_works":["https://openalex.org/W4394405790","https://openalex.org/W4394173855","https://openalex.org/W4394152616","https://openalex.org/W3117328652","https://openalex.org/W4225403904","https://openalex.org/W2048343686","https://openalex.org/W2184072762","https://openalex.org/W2148638118","https://openalex.org/W2102601764","https://openalex.org/W133175500"],"abstract_inverted_index":{"Additional":[0],"file":[1],"1:":[2],"Table":[3],"S1.":[4],"Differentially":[5],"expressed":[6],"genes":[7],"within":[8],"pathways.":[9]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2024-04-08T00:00:00"}