{"id":"https://openalex.org/W4394357089","doi":"https://doi.org/10.6084/m9.figshare.20222846","title":"Epg5 deficiency leads to primary ovarian insufficiency due to WT1 accumulation in mouse granulosa cells","display_name":"Epg5 deficiency leads to primary ovarian insufficiency due to WT1 accumulation in mouse granulosa cells","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4394357089","doi":"https://doi.org/10.6084/m9.figshare.20222846"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/20222846","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/_i_Epg5_i_deficiency_leads_to_primary_ovarian_insufficiency_due_to_WT1_accumulation_in_mouse_granulosa_cells/20222846","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"volume":null,"type":"dataset","is_traditional":false,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/dataset/_i_Epg5_i_deficiency_leads_to_primary_ovarian_insufficiency_due_to_WT1_accumulation_in_mouse_granulosa_cells/20222846","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100343159","display_name":"W\u00e9nw\u00e9n Li\u00fa","orcid":"https://orcid.org/0000-0001-7239-0851","observed_orcids":["https://orcid.org/0000-0001-7239-0851","https://orcid.org/0009-0001-3901-2338","https://orcid.org/0009-0007-9122-0496"]},"institutions":[{"id":"https://openalex.org/I117331123","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662","country_code":"CN","type":"education","lineage":["https://openalex.org/I117331123"]},{"id":"https://openalex.org/I4210138501","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210158139","display_name":"Qingdao Institute of Bioenergy and Bioprocess Technology","ror":"https://ror.org/05h3vcy91","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210158139"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liu, Wenwen","raw_affiliation_strings":["Chinese Academy of Agricultural Sciences","Qingdao Institute of Bioenergy and Bioprocess Technology","Weifang Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Agricultural Sciences","institution_ids":["https://openalex.org/I4210138501"]},{"raw_affiliation_string":"Qingdao Institute of Bioenergy and Bioprocess Technology","institution_ids":["https://openalex.org/I4210158139"]},{"raw_affiliation_string":"Weifang Medical University","institution_ids":["https://openalex.org/I117331123"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chen, Min","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I119454577","display_name":"Nanjing Agricultural University","ror":"https://ror.org/05td3s095","country_code":"CN","type":"education","lineage":["https://openalex.org/I119454577"]},{"id":"https://openalex.org/I129708740","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64","country_code":"CN","type":"education","lineage":["https://openalex.org/I129708740"]},{"id":"https://openalex.org/I176834541","display_name":"Guangdong Medical College","ror":"https://ror.org/04k5rxe29","country_code":"CN","type":"education","lineage":["https://openalex.org/I176834541"]},{"id":"https://openalex.org/I187400657","display_name":"South China Normal University","ror":"https://ror.org/01kq0pv72","country_code":"CN","type":"education","lineage":["https://openalex.org/I187400657"]},{"id":"https://openalex.org/I191208505","display_name":"Xiamen University","ror":"https://ror.org/00mcjh785","country_code":"CN","type":"education","lineage":["https://openalex.org/I191208505"]},{"id":"https://openalex.org/I194450716","display_name":"Jilin University","ror":"https://ror.org/00js3aw79","country_code":"CN","type":"education","lineage":["https://openalex.org/I194450716"]},{"id":"https://openalex.org/I28006308","display_name":"Shandong Normal University","ror":"https://ror.org/01wy3h363","country_code":"CN","type":"education","lineage":["https://openalex.org/I28006308"]},{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4210092091","display_name":"Third Affiliated Hospital of Guangzhou Medical University","ror":"https://ror.org/00fb35g87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210092091"]},{"id":"https://openalex.org/I4210097509","display_name":"Second Affiliated Hospital of Chongqing Medical University","ror":"https://ror.org/00r67fz39","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097509"]},{"id":"https://openalex.org/I4210099004","display_name":"Guangdong Academy of Agricultural Sciences","ror":"https://ror.org/01rkwtz72","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210099004"]},{"id":"https://openalex.org/I4210106526","display_name":"Northwest Institute of Eco-Environment and Resources","ror":"https://ror.org/01jz1e142","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106526"]},{"id":"https://openalex.org/I4210111013","display_name":"Nanjing Drum Tower Hospital","ror":"https://ror.org/026axqv54","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210111013"]},{"id":"https://openalex.org/I4210114896","display_name":"The First Hospital of Kunming","ror":"https://ror.org/01hq7pd83","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210114896"]},{"id":"https://openalex.org/I4210123555","display_name":"Yunnan Center for Disease Control And Prevention","ror":"https://ror.org/02qdc7q41","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210123555"]},{"id":"https://openalex.org/I4210130930","display_name":"Peking University First Hospital","ror":"https://ror.org/02z1vqm45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210130930"]},{"id":"https://openalex.org/I4210148045","display_name":"Science and Technology Commission of Shanghai Municipality","ror":"https://ror.org/03kt66j61","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210148045","https://openalex.org/I4210165456"]},{"id":"https://openalex.org/I4210158097","display_name":"Institute of Botany","ror":"https://ror.org/05hr3ch11","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210158097"]},{"id":"https://openalex.org/I47689461","display_name":"Northeast Forestry University","ror":"https://ror.org/02yxnh564","country_code":"CN","type":"education","lineage":["https://openalex.org/I47689461"]},{"id":"https://openalex.org/I52180223","display_name":"Hunan Agricultural University","ror":"https://ror.org/01dzed356","country_code":"CN","type":"education","lineage":["https://openalex.org/I52180223"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]},{"id":"https://openalex.org/I66867065","display_name":"East China Normal University","ror":"https://ror.org/02n96ep67","country_code":"CN","type":"education","lineage":["https://openalex.org/I66867065"]},{"id":"https://openalex.org/I76569877","display_name":"Southeast University","ror":"https://ror.org/04ct4d772","country_code":"CN","type":"education","lineage":["https://openalex.org/I76569877"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]},{"id":"https://openalex.org/I96478251","display_name":"Hunan Institute of Technology","ror":"https://ror.org/04n3k2k71","country_code":"CN","type":"education","lineage":["https://openalex.org/I96478251"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chen, Min","raw_affiliation_strings":["East China Normal University","Fujian Medical University","Guangdong Academy of Agricultural Sciences","Guangdong Medical College","Hunan Agricultural University","Hunan Institute of Technology","Institute of Botany","Jilin University","Nanjing Agricultural University","Nanjing Drum Tower Hospital","Nanjing Medical University","Northeast Forestry University","Northwest Institute of Eco-Environment and Resources","Peking University First Hospital","Science and Technology Commission of Shanghai Municipality","Second Affiliated Hospital of Chongqing Medical University","Shandong Normal University","South China Normal University","Southeast University","Southern Medical University","The First Hospital of Kunming","Third Affiliated Hospital of Guangzhou Medical University","Union Hospital","Wuhan University","Xiamen University","Yunnan Center for Disease Control And Prevention"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"East China Normal University","institution_ids":["https://openalex.org/I66867065"]},{"raw_affiliation_string":"Fujian Medical University","institution_ids":["https://openalex.org/I129708740"]},{"raw_affiliation_string":"Guangdong Academy of Agricultural Sciences","institution_ids":["https://openalex.org/I4210099004"]},{"raw_affiliation_string":"Guangdong Medical College","institution_ids":["https://openalex.org/I176834541"]},{"raw_affiliation_string":"Hunan Agricultural University","institution_ids":["https://openalex.org/I52180223"]},{"raw_affiliation_string":"Hunan Institute of Technology","institution_ids":["https://openalex.org/I96478251"]},{"raw_affiliation_string":"Institute of Botany","institution_ids":["https://openalex.org/I4210158097"]},{"raw_affiliation_string":"Jilin University","institution_ids":["https://openalex.org/I194450716"]},{"raw_affiliation_string":"Nanjing Agricultural University","institution_ids":["https://openalex.org/I119454577"]},{"raw_affiliation_string":"Nanjing Drum Tower Hospital","institution_ids":["https://openalex.org/I4210111013"]},{"raw_affiliation_string":"Nanjing Medical University","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"Northeast Forestry University","institution_ids":["https://openalex.org/I47689461"]},{"raw_affiliation_string":"Northwest Institute of Eco-Environment and Resources","institution_ids":["https://openalex.org/I4210106526"]},{"raw_affiliation_string":"Peking University First Hospital","institution_ids":["https://openalex.org/I4210130930"]},{"raw_affiliation_string":"Science and Technology Commission of Shanghai Municipality","institution_ids":["https://openalex.org/I4210148045"]},{"raw_affiliation_string":"Second Affiliated Hospital of Chongqing Medical University","institution_ids":["https://openalex.org/I4210097509"]},{"raw_affiliation_string":"Shandong Normal University","institution_ids":["https://openalex.org/I28006308"]},{"raw_affiliation_string":"South China Normal University","institution_ids":["https://openalex.org/I187400657"]},{"raw_affiliation_string":"Southeast University","institution_ids":["https://openalex.org/I76569877"]},{"raw_affiliation_string":"Southern Medical University","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"The First Hospital of Kunming","institution_ids":["https://openalex.org/I4210114896"]},{"raw_affiliation_string":"Third Affiliated Hospital of Guangzhou Medical University","institution_ids":["https://openalex.org/I4210092091"]},{"raw_affiliation_string":"Union Hospital","institution_ids":[]},{"raw_affiliation_string":"Wuhan University","institution_ids":["https://openalex.org/I37461747"]},{"raw_affiliation_string":"Xiamen University","institution_ids":["https://openalex.org/I191208505"]},{"raw_affiliation_string":"Yunnan Center for Disease Control And Prevention","institution_ids":["https://openalex.org/I4210123555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100362936","display_name":"Chao Liu","orcid":"https://orcid.org/0000-0002-8844-0697","observed_orcids":["https://orcid.org/0000-0002-8844-0697"]},"institutions":[{"id":"https://openalex.org/I107982497","display_name":"Dalian Ocean University","ror":"https://ror.org/0523b6g79","country_code":"CN","type":"education","lineage":["https://openalex.org/I107982497"]},{"id":"https://openalex.org/I111381250","display_name":"Hebei Medical University","ror":"https://ror.org/04eymdx19","country_code":"CN","type":"education","lineage":["https://openalex.org/I111381250"]},{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I182386381","display_name":"Zunyi Medical University","ror":"https://ror.org/00g5b0g93","country_code":"CN","type":"education","lineage":["https://openalex.org/I182386381"]},{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I186272606","display_name":"Guangdong University of Foreign Studies","ror":"https://ror.org/00fhc9y79","country_code":"CN","type":"education","lineage":["https://openalex.org/I186272606"]},{"id":"https://openalex.org/I191208505","display_name":"Xiamen University","ror":"https://ror.org/00mcjh785","country_code":"CN","type":"education","lineage":["https://openalex.org/I191208505"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I31683504","display_name":"Beijing Forestry University","ror":"https://ror.org/04xv2pc41","country_code":"CN","type":"education","lineage":["https://openalex.org/I1327237609","https://openalex.org/I31683504","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I34949971","display_name":"University of Jinan","ror":"https://ror.org/02mjz6f26","country_code":"CN","type":"education","lineage":["https://openalex.org/I34949971"]},{"id":"https://openalex.org/I4210105982","display_name":"Guangzhou Women and Children Medical Center","ror":"https://ror.org/01g53at17","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105982"]},{"id":"https://openalex.org/I4210106325","display_name":"Shandong Academy of Agricultural Sciences","ror":"https://ror.org/01fbgjv04","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210106325"]},{"id":"https://openalex.org/I4210116869","display_name":"Affiliated Hospital of Qingdao University","ror":"https://ror.org/026e9yy16","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210116869"]},{"id":"https://openalex.org/I4210128284","display_name":"Institute of Optics and Electronics, Chinese Academy of Sciences","ror":"https://ror.org/02bn68w95","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210128284"]},{"id":"https://openalex.org/I4210141942","display_name":"Peking University Third Hospital","ror":"https://ror.org/04wwqze12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141942"]},{"id":"https://openalex.org/I4210150172","display_name":"First Affiliated Hospital of Bengbu Medical College","ror":"https://ror.org/04v043n92","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210150172"]},{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I4210153519","display_name":"First Affiliated Hospital of Soochow University","ror":"https://ror.org/051jg5p78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153519"]},{"id":"https://openalex.org/I4210162753","display_name":"First Affiliated Hospital of Jinan University","ror":"https://ror.org/05d5vvz89","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210162753"]},{"id":"https://openalex.org/I4210163399","display_name":"Shandong First Medical University","ror":"https://ror.org/05jb9pq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210163399"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I44468530","display_name":"Qingdao University of Technology","ror":"https://ror.org/01qzc0f54","country_code":"CN","type":"education","lineage":["https://openalex.org/I44468530"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]},{"id":"https://openalex.org/I91935597","display_name":"University of South China","ror":"https://ror.org/03mqfn238","country_code":"CN","type":"education","lineage":["https://openalex.org/I91935597"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liu, Chao","raw_affiliation_strings":["Affiliated Hospital of Qingdao University","Beijing Forestry University","Central South University","Chinese Academy of Medical Sciences & Peking Union Medical College","Chinese Academy of Sciences","Dalian Ocean University","First Affiliated Hospital of Bengbu Medical College","First Affiliated Hospital of Jinan University","First Affiliated Hospital of Soochow University","Guangdong University of Foreign Studies","Guangzhou Women and Children Medical Center","Harbin Medical University","Hebei Medical University","Huazhong University of Science and Technology","Institute of Optics and Electronics","Jiangsu Province Hospital","Peking University Third Hospital","Qingdao University of Technology","Shandong Academy of Agricultural Sciences","Shandong Academy of Medical Science","Shanghai Jiao Tong University","University of Chinese Academy of Sciences","University of South China","Xiamen University","Zhejiang University","Zunyi Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliated Hospital of Qingdao University","institution_ids":["https://openalex.org/I4210116869"]},{"raw_affiliation_string":"Beijing Forestry University","institution_ids":["https://openalex.org/I31683504"]},{"raw_affiliation_string":"Central South University","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"Chinese Academy of Medical Sciences & Peking Union Medical College","institution_ids":["https://openalex.org/I200296433"]},{"raw_affiliation_string":"Chinese Academy of Sciences","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"Dalian Ocean University","institution_ids":["https://openalex.org/I107982497"]},{"raw_affiliation_string":"First Affiliated Hospital of Bengbu Medical College","institution_ids":["https://openalex.org/I4210150172"]},{"raw_affiliation_string":"First Affiliated Hospital of Jinan University","institution_ids":["https://openalex.org/I34949971","https://openalex.org/I4210162753"]},{"raw_affiliation_string":"First Affiliated Hospital of Soochow University","institution_ids":["https://openalex.org/I4210153519"]},{"raw_affiliation_string":"Guangdong University of Foreign Studies","institution_ids":["https://openalex.org/I186272606"]},{"raw_affiliation_string":"Guangzhou Women and Children Medical Center","institution_ids":["https://openalex.org/I4210105982"]},{"raw_affiliation_string":"Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]},{"raw_affiliation_string":"Hebei Medical University","institution_ids":["https://openalex.org/I111381250"]},{"raw_affiliation_string":"Huazhong University of Science and Technology","institution_ids":["https://openalex.org/I47720641"]},{"raw_affiliation_string":"Institute of Optics and Electronics","institution_ids":["https://openalex.org/I4210128284"]},{"raw_affiliation_string":"Jiangsu Province Hospital","institution_ids":["https://openalex.org/I4210152119"]},{"raw_affiliation_string":"Peking University Third Hospital","institution_ids":["https://openalex.org/I4210141942"]},{"raw_affiliation_string":"Qingdao University of Technology","institution_ids":["https://openalex.org/I44468530"]},{"raw_affiliation_string":"Shandong Academy of Agricultural Sciences","institution_ids":["https://openalex.org/I4210106325"]},{"raw_affiliation_string":"Shandong Academy of Medical Science","institution_ids":["https://openalex.org/I4210163399"]},{"raw_affiliation_string":"Shanghai Jiao Tong University","institution_ids":["https://openalex.org/I183067930"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences","institution_ids":["https://openalex.org/I4210165038"]},{"raw_affiliation_string":"University of South China","institution_ids":["https://openalex.org/I91935597"]},{"raw_affiliation_string":"Xiamen University","institution_ids":["https://openalex.org/I191208505"]},{"raw_affiliation_string":"Zhejiang University","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"Zunyi Medical University","institution_ids":["https://openalex.org/I182386381"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wang, Liying","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125137","display_name":"First Hospital of Jilin University","ror":"https://ror.org/034haf133","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125137"]},{"id":"https://openalex.org/I85430964","display_name":"Jinzhou Medical University","ror":"https://ror.org/02yd1yr68","country_code":"CN","type":"education","lineage":["https://openalex.org/I85430964"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wang, Liying","raw_affiliation_strings":["First Hospital of Jilin University","Liaoning Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Hospital of Jilin University","institution_ids":["https://openalex.org/I4210125137"]},{"raw_affiliation_string":"Liaoning Medical University","institution_ids":["https://openalex.org/I85430964"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013734736","display_name":"Huafang Wei","orcid":"https://orcid.org/0009-0007-0296-4507","observed_orcids":["https://orcid.org/0009-0007-0296-4507","https://orcid.org/0000-0002-8087-0262"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wei, Huafang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064251070","display_name":"Ruidan Zhang","orcid":"https://orcid.org/0000-0002-4924-8766","observed_orcids":["https://orcid.org/0000-0002-4924-8766"]},"institutions":[{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhang, Ruidan","raw_affiliation_strings":["University of Chinese Academy of Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Chinese Academy of Sciences","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073628677","display_name":"Zhengxing Ren","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ren, Zhengxing","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101746088","display_name":"Yinghong Chen","orcid":"https://orcid.org/0000-0003-2208-4105","observed_orcids":["https://orcid.org/0000-0003-2208-4105"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chen, Yinghong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067444550","display_name":"Mengcheng Luo","orcid":"https://orcid.org/0000-0001-7058-5911","observed_orcids":["https://orcid.org/0000-0001-7058-5911"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luo, Mengcheng","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057825204","display_name":"Jianguo Zhao","orcid":"https://orcid.org/0000-0001-6587-4823","observed_orcids":["https://orcid.org/0000-0001-6587-4823"]},"institutions":[{"id":"https://openalex.org/I5422934","display_name":"Shanxi Datong University","ror":"https://ror.org/03s8xc553","country_code":"CN","type":"education","lineage":["https://openalex.org/I5422934"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhao, Jianguo","raw_affiliation_strings":["Shanxi Datong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Datong University","institution_ids":["https://openalex.org/I5422934"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056125499","display_name":"Hongwei\ufffd Jiang","orcid":"https://orcid.org/0000-0003-3807-7989","observed_orcids":["https://orcid.org/0000-0003-3807-7989"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jiang, Hongwei","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100720758","display_name":"Fei Gao","orcid":"https://orcid.org/0000-0001-6326-1820","observed_orcids":["https://orcid.org/0000-0001-6326-1820"]},"institutions":[{"id":"https://openalex.org/I145897649","display_name":"Minzu University of China","ror":"https://ror.org/0044e2g62","country_code":"CN","type":"education","lineage":["https://openalex.org/I145897649"]},{"id":"https://openalex.org/I165283593","display_name":"\u00c9cole des Hautes \u00c9tudes en Sant\u00e9 Publique","ror":"https://ror.org/01sc83v92","country_code":"FR","type":"education","lineage":["https://openalex.org/I165283593","https://openalex.org/I56067802"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]},{"id":"https://openalex.org/I38877650","display_name":"Zhengzhou University","ror":"https://ror.org/04ypx8c21","country_code":"CN","type":"education","lineage":["https://openalex.org/I38877650"]},{"id":"https://openalex.org/I4210124606","display_name":"Institute of Genetics and Developmental Biology","ror":"https://ror.org/02aee5m12","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210124606"]},{"id":"https://openalex.org/I4210126319","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I170897317","https://openalex.org/I4210126319"]},{"id":"https://openalex.org/I4210127266","display_name":"First Affiliated Hospital of Chengdu Medical College","ror":"https://ror.org/03jckbw05","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127266"]},{"id":"https://openalex.org/I4210144482","display_name":"Shanghai Sixth People's Hospital","ror":"https://ror.org/049zrh188","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210144482"]},{"id":"https://openalex.org/I4210147238","display_name":"National Heart Centre Singapore","ror":"https://ror.org/04f8k9513","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I4210147238"]},{"id":"https://openalex.org/I53411278","display_name":"Chengdu University of Traditional Chinese Medicine","ror":"https://ror.org/00pcrz470","country_code":"CN","type":"education","lineage":["https://openalex.org/I53411278"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN","FR","SG"],"is_corresponding":false,"raw_author_name":"Gao, Fei","raw_affiliation_strings":["Air Force Medical University","Chengdu University of Traditional Chinese Medicine","Chinese PLA General Hospital","Duke NUS Graduate Medical School","First Affiliated Hospital of Chengdu Medical College","Institute of Genetics and Developmental Biology","Minzu University of China","Nanjing Medical University","National Heart Centre Singapore","Shanghai Sixth People's Hospital","Zhengzhou University","\u00c9cole des Hautes \u00c9tudes en Sant\u00e9 Publique"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Air Force Medical University","institution_ids":["https://openalex.org/I9916479"]},{"raw_affiliation_string":"Chengdu University of Traditional Chinese Medicine","institution_ids":["https://openalex.org/I53411278"]},{"raw_affiliation_string":"Chinese PLA General Hospital","institution_ids":["https://openalex.org/I2802939634"]},{"raw_affiliation_string":"Duke NUS Graduate Medical School","institution_ids":["https://openalex.org/I165932596","https://openalex.org/I4210126319"]},{"raw_affiliation_string":"First Affiliated Hospital of Chengdu Medical College","institution_ids":["https://openalex.org/I4210127266"]},{"raw_affiliation_string":"Institute of Genetics and Developmental Biology","institution_ids":["https://openalex.org/I4210124606"]},{"raw_affiliation_string":"Minzu University of China","institution_ids":["https://openalex.org/I145897649"]},{"raw_affiliation_string":"Nanjing Medical University","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"National Heart Centre Singapore","institution_ids":["https://openalex.org/I4210147238"]},{"raw_affiliation_string":"Shanghai Sixth People's Hospital","institution_ids":["https://openalex.org/I4210144482"]},{"raw_affiliation_string":"Zhengzhou University","institution_ids":["https://openalex.org/I38877650"]},{"raw_affiliation_string":"\u00c9cole des Hautes \u00c9tudes en Sant\u00e9 Publique","institution_ids":["https://openalex.org/I165283593"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100318325","display_name":"W\u011bi Li","orcid":"https://orcid.org/0000-0002-9522-4474","observed_orcids":["https://orcid.org/0000-0002-9522-4474","https://orcid.org/0000-0003-4136-3409","https://orcid.org/0009-0009-9141-6389"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I120379545","display_name":"Inner Mongolia Agricultural University","ror":"https://ror.org/015d0jq83","country_code":"CN","type":"education","lineage":["https://openalex.org/I120379545"]},{"id":"https://openalex.org/I126520041","display_name":"University of Science and Technology of China","ror":"https://ror.org/04c4dkn09","country_code":"CN","type":"education","lineage":["https://openalex.org/I126520041","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]},{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]},{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I167027274","display_name":"Nanjing Forestry University","ror":"https://ror.org/03m96p165","country_code":"CN","type":"education","lineage":["https://openalex.org/I167027274"]},{"id":"https://openalex.org/I169572211","display_name":"Northeast Agricultural University","ror":"https://ror.org/0515nd386","country_code":"CN","type":"education","lineage":["https://openalex.org/I169572211"]},{"id":"https://openalex.org/I176834541","display_name":"Guangdong Medical College","ror":"https://ror.org/04k5rxe29","country_code":"CN","type":"education","lineage":["https://openalex.org/I176834541"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I194450716","display_name":"Jilin University","ror":"https://ror.org/00js3aw79","country_code":"CN","type":"education","lineage":["https://openalex.org/I194450716"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I200845125","display_name":"Nanjing University of Information Science and Technology","ror":"https://ror.org/02y0rxk19","country_code":"CN","type":"education","lineage":["https://openalex.org/I200845125"]},{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]},{"id":"https://openalex.org/I2801051648","display_name":"China-Japan Friendship Hospital","ror":"https://ror.org/037cjxp13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801051648"]},{"id":"https://openalex.org/I38877650","display_name":"Zhengzhou University","ror":"https://ror.org/04ypx8c21","country_code":"CN","type":"education","lineage":["https://openalex.org/I38877650"]},{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]},{"id":"https://openalex.org/I4210089584","display_name":"Institute of Hydrobiology","ror":"https://ror.org/00b4mx203","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210089584"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]},{"id":"https://openalex.org/I4210100054","display_name":"Heilongjiang Provincial Academy of Agricultural Sciences","ror":"https://ror.org/00zxgrh39","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210100054"]},{"id":"https://openalex.org/I4210105982","display_name":"Guangzhou Women and Children Medical Center","ror":"https://ror.org/01g53at17","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105982"]},{"id":"https://openalex.org/I4210108664","display_name":"International Peace Maternity & Child Health Hospital","ror":"https://ror.org/01byttc20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108664"]},{"id":"https://openalex.org/I4210115919","display_name":"The People's Hospital of Guangxi Zhuang Autonomous Region","ror":"https://ror.org/02aa8kj12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115919"]},{"id":"https://openalex.org/I4210124971","display_name":"Second Affiliated Hospital of Soochow University","ror":"https://ror.org/02xjrkt08","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124971"]},{"id":"https://openalex.org/I4210125137","display_name":"First Hospital of Jilin University","ror":"https://ror.org/034haf133","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125137"]},{"id":"https://openalex.org/I4210128921","display_name":"The First Affiliated Hospital, Sun Yat-sen University","ror":"https://ror.org/037p24858","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128921"]},{"id":"https://openalex.org/I4210141942","display_name":"Peking University Third Hospital","ror":"https://ror.org/04wwqze12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141942"]},{"id":"https://openalex.org/I4210143603","display_name":"Institute of Hydrobiology, Biology Centre, Academy of Sciences of the Czech Republic","ror":"https://ror.org/0436nxt45","country_code":"CZ","type":"facility","lineage":["https://openalex.org/I202391551","https://openalex.org/I4210143603","https://openalex.org/I4210164740"]},{"id":"https://openalex.org/I4210146685","display_name":"National Institute for Communicable Disease Control and Prevention","ror":"https://ror.org/04f7g6845","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210146685","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210151382","display_name":"Children's Hospital of Suzhou University","ror":"https://ror.org/05a9skj35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210151382"]},{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I4210156804","display_name":"First Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/056swr059","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156804"]},{"id":"https://openalex.org/I4210157729","display_name":"First Affiliated Hospital of Hebei Medical University","ror":"https://ror.org/04z3aby64","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210157729"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]},{"id":"https://openalex.org/I4210160531","display_name":"Chinese People's Liberation Army","ror":"https://ror.org/05tf9r976","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210160531"]},{"id":"https://openalex.org/I4210160553","display_name":"Children's Hospital of Capital Institute of Pediatrics","ror":"https://ror.org/05hyj7861","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105514","https://openalex.org/I4210160553"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I47689461","display_name":"Northeast Forestry University","ror":"https://ror.org/02yxnh564","country_code":"CN","type":"education","lineage":["https://openalex.org/I47689461"]},{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]},{"id":"https://openalex.org/I68986083","display_name":"Northwest Normal University","ror":"https://ror.org/00gx3j908","country_code":"CN","type":"education","lineage":["https://openalex.org/I68986083"]},{"id":"https://openalex.org/I74485261","display_name":"Shandong Agricultural University","ror":"https://ror.org/02ke8fw32","country_code":"CN","type":"education","lineage":["https://openalex.org/I74485261"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]},{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN","CZ","US"],"is_corresponding":false,"raw_author_name":"Li, Wei","raw_affiliation_strings":["Air Force Medical University","Army Medical University","Baylor College of Medicine","Capital Medical University","Central South University","Children's Hospital of Capital Institute of Pediatrics","Children's Hospital of Suzhou University","China-Japan Friendship Hospital","Chinese Academy of Medical Sciences & Peking Union Medical College","Chinese Academy of Sciences","First Affiliated Hospital of Hebei Medical University","First Affiliated Hospital of Sun Yat-sen University","First Affiliated Hospital of Zhengzhou University","First Hospital of Jilin University","Guangdong Medical College","Guangzhou Women and Children Medical Center","Heilongjiang Provincial Academy of Agricultural Sciences","Indiana University \u2013 Purdue University Indianapolis","Inner Mongolia Agricultural University","Institute for Stem Cell and Regenerative Medicine","Institute of Hydrobiology","International Peace Maternity & Child Health Hospital","Jiangsu Province Hospital","Jilin University","Ministry of Education of the People's Republic of China","Nanjing Forestry University","Nanjing University of Information Science and Technology","National Institute for Communicable Disease Control and Prevention","Northeast Agricultural University","Northeast Forestry University","Northwest Normal University","Peking University","Peking University Third Hospital","People's Liberation Army","Second Affiliated Hospital of Soochow University","Shandong Agricultural University","Shandong University","Shanghai Jiao Tong University","Soochow University","The People's Hospital of Guangxi Zhuang Autonomous Region","Tongji University","Tsinghua University","University of California, Irvine","University of Chinese Academy of Sciences","University of Electronic Science and Technology of China","University of Science and Technology of China","West China Hospital of Sichuan University","Xi'an Jiaotong University","Xiangya Hospital Central South University","Zhengzhou University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Air Force Medical University","institution_ids":["https://openalex.org/I9916479"]},{"raw_affiliation_string":"Army Medical University","institution_ids":["https://openalex.org/I151075929"]},{"raw_affiliation_string":"Baylor College of Medicine","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Capital Medical University","institution_ids":["https://openalex.org/I183519381"]},{"raw_affiliation_string":"Central South University","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"Children's Hospital of Capital Institute of Pediatrics","institution_ids":["https://openalex.org/I4210160553"]},{"raw_affiliation_string":"Children's Hospital of Suzhou University","institution_ids":["https://openalex.org/I4210151382"]},{"raw_affiliation_string":"China-Japan Friendship Hospital","institution_ids":["https://openalex.org/I2801051648"]},{"raw_affiliation_string":"Chinese Academy of Medical Sciences & Peking Union Medical College","institution_ids":["https://openalex.org/I200296433"]},{"raw_affiliation_string":"Chinese Academy of Sciences","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"First Affiliated Hospital of Hebei Medical University","institution_ids":["https://openalex.org/I4210157729"]},{"raw_affiliation_string":"First Affiliated Hospital of Sun Yat-sen University","institution_ids":["https://openalex.org/I4210128921"]},{"raw_affiliation_string":"First Affiliated Hospital of Zhengzhou University","institution_ids":["https://openalex.org/I4210156804"]},{"raw_affiliation_string":"First Hospital of Jilin University","institution_ids":["https://openalex.org/I4210125137"]},{"raw_affiliation_string":"Guangdong Medical College","institution_ids":["https://openalex.org/I176834541"]},{"raw_affiliation_string":"Guangzhou Women and Children Medical Center","institution_ids":["https://openalex.org/I4210105982"]},{"raw_affiliation_string":"Heilongjiang Provincial Academy of Agricultural Sciences","institution_ids":["https://openalex.org/I4210100054"]},{"raw_affiliation_string":"Indiana University \u2013 Purdue University Indianapolis","institution_ids":["https://openalex.org/I55769427"]},{"raw_affiliation_string":"Inner Mongolia Agricultural University","institution_ids":["https://openalex.org/I120379545"]},{"raw_affiliation_string":"Institute for Stem Cell and Regenerative Medicine","institution_ids":[]},{"raw_affiliation_string":"Institute of Hydrobiology","institution_ids":["https://openalex.org/I4210089584","https://openalex.org/I4210143603"]},{"raw_affiliation_string":"International Peace Maternity & Child Health Hospital","institution_ids":["https://openalex.org/I4210108664"]},{"raw_affiliation_string":"Jiangsu Province Hospital","institution_ids":["https://openalex.org/I4210152119"]},{"raw_affiliation_string":"Jilin University","institution_ids":["https://openalex.org/I194450716"]},{"raw_affiliation_string":"Ministry of Education of the People's Republic of China","institution_ids":["https://openalex.org/I1327237609"]},{"raw_affiliation_string":"Nanjing Forestry University","institution_ids":["https://openalex.org/I167027274"]},{"raw_affiliation_string":"Nanjing University of Information Science and Technology","institution_ids":["https://openalex.org/I200845125"]},{"raw_affiliation_string":"National Institute for Communicable Disease Control and Prevention","institution_ids":["https://openalex.org/I4210146685"]},{"raw_affiliation_string":"Northeast Agricultural University","institution_ids":["https://openalex.org/I169572211"]},{"raw_affiliation_string":"Northeast Forestry University","institution_ids":["https://openalex.org/I47689461"]},{"raw_affiliation_string":"Northwest Normal University","institution_ids":["https://openalex.org/I68986083"]},{"raw_affiliation_string":"Peking University","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Peking University Third Hospital","institution_ids":["https://openalex.org/I4210141942"]},{"raw_affiliation_string":"People's Liberation Army","institution_ids":["https://openalex.org/I4210160531"]},{"raw_affiliation_string":"Second Affiliated Hospital of Soochow University","institution_ids":["https://openalex.org/I4210124971"]},{"raw_affiliation_string":"Shandong Agricultural University","institution_ids":["https://openalex.org/I74485261"]},{"raw_affiliation_string":"Shandong University","institution_ids":["https://openalex.org/I154099455"]},{"raw_affiliation_string":"Shanghai Jiao Tong University","institution_ids":["https://openalex.org/I183067930"]},{"raw_affiliation_string":"Soochow University","institution_ids":["https://openalex.org/I3923682"]},{"raw_affiliation_string":"The People's Hospital of Guangxi Zhuang Autonomous Region","institution_ids":["https://openalex.org/I4210115919"]},{"raw_affiliation_string":"Tongji University","institution_ids":["https://openalex.org/I116953780"]},{"raw_affiliation_string":"Tsinghua University","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"University of California, Irvine","institution_ids":["https://openalex.org/I204250578"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences","institution_ids":["https://openalex.org/I4210165038"]},{"raw_affiliation_string":"University of Electronic Science and Technology of China","institution_ids":["https://openalex.org/I150229711"]},{"raw_affiliation_string":"University of Science and Technology of China","institution_ids":["https://openalex.org/I126520041"]},{"raw_affiliation_string":"West China Hospital of Sichuan University","institution_ids":["https://openalex.org/I4210089761"]},{"raw_affiliation_string":"Xi'an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"Xiangya Hospital Central South University","institution_ids":["https://openalex.org/I4210159865"]},{"raw_affiliation_string":"Zhengzhou University","institution_ids":["https://openalex.org/I38877650"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":105,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.6855000257492065,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.6855000257492065,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.305400013923645,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epg5","display_name":"EPG5","score":0.9020000100135803},{"id":"https://openalex.org/keywords/primary-ovarian-insufficiency","display_name":"primary ovarian insufficiency","score":0.9829999804496765},{"id":"https://openalex.org/keywords/premature-ovarian-failure","display_name":"premature ovarian failure","score":0.9589999914169312},{"id":"https://openalex.org/keywords/granulosa-cells","display_name":"granulosa cells","score":0.9079999923706055},{"id":"https://openalex.org/keywords/wt1","display_name":"WT1","score":0.8009999990463257},{"id":"https://openalex.org/keywords/autophagy","display_name":"autophagy","score":0.8080000281333923},{"id":"https://openalex.org/keywords/selective-autophagy","display_name":"selective autophagy","score":0.6449999809265137},{"id":"https://openalex.org/keywords/protein-degradation","display_name":"protein degradation","score":0.8429999947547913},{"id":"https://openalex.org/keywords/granulosa-cell-differentiation","display_name":"granulosa cell differentiation","score":0.8730000257492065},{"id":"https://openalex.org/keywords/steroidogenesis","display_name":"steroidogenesis","score":0.9369999766349792},{"id":"https://openalex.org/keywords/antral-follicles","display_name":"antral follicles","score":0.7269999980926514},{"id":"https://openalex.org/keywords/subfertility","display_name":"subfertility","score":0.7229999899864197},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.34700000286102295}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5018858909606934},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5010809898376465},{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.4329510033130646},{"id":"https://openalex.org/C2777977315","wikidata":"https://www.wikidata.org/wiki/Q7243056","display_name":"Primary (astronomy)","level":2,"score":0.425988107919693},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4153320789337158},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.35697102546691895},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35151541233062744},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.09444618225097656},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.08858489990234375},{"id":"https://openalex.org/C1276947","wikidata":"https://www.wikidata.org/wiki/Q333","display_name":"Astronomy","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/20222846","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/_i_Epg5_i_deficiency_leads_to_primary_ovarian_insufficiency_due_to_WT1_accumulation_in_mouse_granulosa_cells/20222846","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.20222846","doi":"https://doi.org/10.6084/m9.figshare.20222846","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.20222846","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.20222846.v1","doi":"https://doi.org/10.6084/m9.figshare.20222846.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.20222846.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/20222846","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/_i_Epg5_i_deficiency_leads_to_primary_ovarian_insufficiency_due_to_WT1_accumulation_in_mouse_granulosa_cells/20222846","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4206380528","https://openalex.org/W1974231851","https://openalex.org/W4409583330","https://openalex.org/W4366518188","https://openalex.org/W3177319807","https://openalex.org/W2135423227","https://openalex.org/W2515590801","https://openalex.org/W3159173150","https://openalex.org/W4391581729","https://openalex.org/W4412855635"],"abstract_inverted_index":{"Primary":[0],"ovarian":[1,8,12,22,194],"insufficiency":[2],"(POI),":[3],"also":[4],"known":[5],"as":[6],"premature":[7,19],"failure,":[9],"is":[10],"an":[11,99],"defect":[13],"in":[14,53,55,91,124,149,157],"humans":[15],"characterized":[16],"by":[17,112],"the":[18,25,30,69,74,92,113,119,125,153],"depletion":[20],"of":[21,27,42,71,76,85,94,122,133,155],"follicles":[23],"before":[24],"age":[26],"40.":[28],"However,":[29],"mechanisms":[31],"underlying":[32],"POI":[33,161],"remain":[34],"largely":[35],"unknown.":[36],"Here,":[37],"we":[38],"show":[39,143],"that":[40,68,83,118,144,152],"knockout":[41,70,84],"Epg5":[43,72,86,156],"(ectopic":[44],"P-granules":[45,172],"autophagy":[46,114,173],"protein":[47,174,184],"5":[48,175],"homolog":[49,176],"(C.":[50,177],"elegans))":[51],"results":[52],"subfertility":[54],"female":[56],"mice,":[57],"which":[58],"exhibit":[59],"a":[60],"POI-like":[61],"phenotype.":[62],"Single-cell":[63],"RNA":[64],"sequencing":[65],"analysis":[66],"revealed":[67],"affected":[73],"differentiation":[75],"granulosa":[77,180],"cells":[78],"(GCs).":[79],"Further":[80],"investigation":[81],"demonstrated":[82],"blocks":[87],"macroautophagic/autophagic":[88],"flux,":[89],"resulting":[90],"accumulation":[93],"WT1":[95,106,123,147,204],"(WT1":[96],"transcription":[97,101,205],"factor),":[98],"essential":[100],"factor":[102,206],"for":[103],"GCs,":[104,150],"suggesting":[105],"needs":[107],"to":[108,130],"be":[109],"selectively":[110],"degraded":[111],"pathway.":[115],"We":[116],"found":[117],"insufficient":[120],"degradation":[121,148],"antral":[126],"follicular":[127],"stage":[128],"contributes":[129],"reduced":[131],"expression":[132],"steroidogenesis-related":[134],"genes,":[135],"thereby":[136],"disrupting":[137],"GC":[138],"differentiation.":[139],"Collectively,":[140],"our":[141],"studies":[142],"EPG5":[145],"promotes":[146],"indicating":[151],"dysregulation":[154],"GCs":[158],"can":[159],"trigger":[160],"pathogenesis.":[162],"Abbreviations:":[163],"3-MA,":[164],"3-methyladenine;":[165],"CHX,":[166],"cycloheximide;":[167],"CQ,":[168],"chloroquine;":[169],"EPG5,":[170],"ectopic":[171],"elegans);":[178],"GC,":[179],"cell;":[181],"MAP1LC3/LC3,":[182],"microtubule-associated":[183],"1":[185],"light":[186],"chain":[187],"3;":[188],"MII,":[189],"metaphase":[190],"II;":[191],"POI,":[192],"primary":[193],"insufficiency;":[195],"PB1,":[196],"polar":[197],"body":[198],"1;":[199,202],"SQSTM1/p62,":[200],"sequestosome":[201],"WT1,":[203]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-04-08T00:00:00"}