{"id":"https://openalex.org/W4394222002","doi":"https://doi.org/10.6084/m9.figshare.20727634","title":"Additional file 1 of Markers of endothelial glycocalyx dysfunction in Clarkson disease","display_name":"Additional file 1 of Markers of endothelial glycocalyx dysfunction in Clarkson disease","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4394222002","doi":"https://doi.org/10.6084/m9.figshare.20727634"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/20727634","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_1_of_Markers_of_endothelial_glycocalyx_dysfunction_in_Clarkson_disease/20727634","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"volume":null,"type":"dataset","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/dataset/Additional_file_1_of_Markers_of_endothelial_glycocalyx_dysfunction_in_Clarkson_disease/20727634","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023092411","display_name":"Zhihui Xie","orcid":"https://orcid.org/0000-0002-1556-0700","observed_orcids":["https://orcid.org/0000-0002-1556-0700"]},"institutions":[{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xie, Zhihui","raw_affiliation_strings":["National Institute of Allergy and Infectious Diseases"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Allergy and Infectious Diseases","institution_ids":["https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009564890","display_name":"Magne B\u00f8rset","orcid":"https://orcid.org/0000-0001-5179-2835","observed_orcids":["https://orcid.org/0000-0001-5179-2835"]},"institutions":[{"id":"https://openalex.org/I204778367","display_name":"Norwegian University of Science and Technology","ror":"https://ror.org/05xg72x27","country_code":"NO","type":"education","lineage":["https://openalex.org/I204778367"]},{"id":"https://openalex.org/I4210104358","display_name":"St Olav's University Hospital","ror":"https://ror.org/01a4hbq44","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I4210104358"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"B\u00f8rset, Magne","raw_affiliation_strings":["St Olav's University Hospital","Norwegian University of Science and Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St Olav's University Hospital","institution_ids":["https://openalex.org/I4210104358"]},{"raw_affiliation_string":"Norwegian University of Science and Technology","institution_ids":["https://openalex.org/I204778367"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044927347","display_name":"Kjell Sv\u00e9en","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204778367","display_name":"Norwegian University of Science and Technology","ror":"https://ror.org/05xg72x27","country_code":"NO","type":"education","lineage":["https://openalex.org/I204778367"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Sv\u00e9en, Kjell","raw_affiliation_strings":["Norwegian University of Science and Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Norwegian University of Science and Technology","institution_ids":["https://openalex.org/I204778367"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083272326","display_name":"Ole Wilhelm B\u00f8e","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204778367","display_name":"Norwegian University of Science and Technology","ror":"https://ror.org/05xg72x27","country_code":"NO","type":"education","lineage":["https://openalex.org/I204778367"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"B\u00f8e, Ole Wilhelm","raw_affiliation_strings":["Norwegian University of Science and Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Norwegian University of Science and Technology","institution_ids":["https://openalex.org/I204778367"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104251400","display_name":"Eunice Ching Chan","orcid":"https://orcid.org/0000-0003-0599-5898","observed_orcids":["https://orcid.org/0000-0003-0599-5898"]},"institutions":[{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chan, Eunice C.","raw_affiliation_strings":["National Institute of Allergy and Infectious Diseases"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Allergy and Infectious Diseases","institution_ids":["https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047748413","display_name":"Justin Lack","orcid":"https://orcid.org/0000-0003-0584-4010","observed_orcids":["https://orcid.org/0000-0003-0584-4010"]},"institutions":[{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lack, Justin B.","raw_affiliation_strings":["National Institute of Allergy and Infectious Diseases"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Allergy and Infectious Diseases","institution_ids":["https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040849276","display_name":"Katherine M. Hornick","orcid":"https://orcid.org/0000-0003-3933-4035","observed_orcids":["https://orcid.org/0000-0003-3933-4035"]},"institutions":[{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hornick, Katherine M.","raw_affiliation_strings":["National Institute of Allergy and Infectious Diseases"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Allergy and Infectious Diseases","institution_ids":["https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038020702","display_name":"Franco Verlicchi","orcid":"https://orcid.org/0000-0003-2833-2288","observed_orcids":["https://orcid.org/0000-0003-2833-2288"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Verlicchi, Franco","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066323479","display_name":"A. Robin Eisch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eisch, A. Robin","raw_affiliation_strings":["National Institute of Allergy and Infectious Diseases"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Allergy and Infectious Diseases","institution_ids":["https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054267598","display_name":"Remo Melchio","orcid":"https://orcid.org/0000-0003-4321-0502","observed_orcids":["https://orcid.org/0000-0003-4321-0502"]},"institutions":[{"id":"https://openalex.org/I4210137935","display_name":"Azienda Sanitaria Ospedaliera S.Croce e Carle Cuneo","ror":"https://ror.org/03pz7fw94","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210137935"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Melchio, Remo","raw_affiliation_strings":["Azienda Sanitaria Ospedaliera S.Croce e Carle Cuneo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Azienda Sanitaria Ospedaliera S.Croce e Carle Cuneo","institution_ids":["https://openalex.org/I4210137935"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090069473","display_name":"Arkadiusz Zbigniew Dudek","orcid":"https://orcid.org/0000-0002-9114-8945","observed_orcids":["https://orcid.org/0000-0002-9114-8945"]},"institutions":[{"id":"https://openalex.org/I52792670","display_name":"HealthPartners","ror":"https://ror.org/03s9ada67","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I52792670"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dudek, Arkadiusz Z.","raw_affiliation_strings":["HealthPartners"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HealthPartners","institution_ids":["https://openalex.org/I52792670"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004382885","display_name":"Kirk M. Druey","orcid":"https://orcid.org/0000-0002-5834-6501","observed_orcids":["https://orcid.org/0000-0002-5834-6501"]},"institutions":[{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Druey, Kirk M.","raw_affiliation_strings":["National Institute of Allergy and Infectious Diseases"],"raw_orcid":"https://orcid.org/0000-0002-5834-6501","affiliations":[{"raw_affiliation_string":"National Institute of Allergy and Infectious Diseases","institution_ids":["https://openalex.org/I4210134534"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11131","display_name":"Proteoglycans and glycosaminoglycans research","score":0.45260000228881836,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11131","display_name":"Proteoglycans and glycosaminoglycans research","score":0.45260000228881836,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.29249998927116394,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10945","display_name":"Lysosomal Storage Disorders Research","score":0.04809999838471413,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/differentially-expressed-genes","display_name":"differentially expressed genes","score":0.8539999723434448},{"id":"https://openalex.org/keywords/rna-sequencing","display_name":"RNA sequencing","score":0.6159999966621399},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.5360000133514404},{"id":"https://openalex.org/keywords/cystic-fibrosis","display_name":"cystic fibrosis","score":0.6039999723434448}],"concepts":[{"id":"https://openalex.org/C2780098789","wikidata":"https://www.wikidata.org/wiki/Q898356","display_name":"Glycocalyx","level":2,"score":0.6308326125144958},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5725098848342896},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.33600372076034546},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22118109464645386},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.18766555190086365}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/20727634","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_1_of_Markers_of_endothelial_glycocalyx_dysfunction_in_Clarkson_disease/20727634","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.20727634","doi":"https://doi.org/10.6084/m9.figshare.20727634","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.20727634","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.20727634.v1","doi":"https://doi.org/10.6084/m9.figshare.20727634.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.20727634.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/20727634","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_1_of_Markers_of_endothelial_glycocalyx_dysfunction_in_Clarkson_disease/20727634","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4394233619","https://openalex.org/W4394367930","https://openalex.org/W4293531839","https://openalex.org/W4392949669","https://openalex.org/W3115821175","https://openalex.org/W4388757437","https://openalex.org/W3100154271","https://openalex.org/W4392055178","https://openalex.org/W2894799848","https://openalex.org/W2115245165"],"abstract_inverted_index":{"Additional":[0],"file":[1],"1.":[2],"Table":[3],"S1":[4],"Differentially":[5],"expressed":[6],"genes":[7],"(DEGs)":[8],"in":[9],"ISCLS":[10],"and":[11],"control":[12],"blood-derived":[13],"endothelial":[14],"cells":[15],"(BOECs)":[16],"detected":[17],"by":[18],"RNA-Seq.":[19]},"counts_by_year":[],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2024-04-08T00:00:00"}