{"id":"https://openalex.org/W4394130331","doi":"https://doi.org/10.6084/m9.figshare.7516658","title":"Comparative analysis of different doses of coherent light (laser) and non-coherent light (light-emitting diode) on cellular necrosis and apoptosis: a study in vitro","display_name":"Comparative analysis of different doses of coherent light (laser) and non-coherent light (light-emitting diode) on cellular necrosis and apoptosis: a study in vitro","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W4394130331","doi":"https://doi.org/10.6084/m9.figshare.7516658"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/7516658","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Comparative_analysis_of_different_doses_of_coherent_light_laser_and_non-coherent_light_light-emitting_diode_on_cellular_necrosis_and_apoptosis_a_study_in_vitro/7516658","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"volume":null,"type":"dataset","is_traditional":false,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/dataset/Comparative_analysis_of_different_doses_of_coherent_light_laser_and_non-coherent_light_light-emitting_diode_on_cellular_necrosis_and_apoptosis_a_study_in_vitro/7516658","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023750545","display_name":"Vanessa S. Silva","orcid":"https://orcid.org/0000-0001-8200-4635","observed_orcids":["https://orcid.org/0000-0001-8200-4635"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Silva, Vanessa Dos Santos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065448832","display_name":"Eliz\u00e2ngela M\u00e1rcia de Carvalho Abreu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eliz\u00e2ngela M\u00e1rcia De Carvalho Abreu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022574517","display_name":"Renata Amadei Nicolau","orcid":"https://orcid.org/0000-0002-7687-7963","observed_orcids":["https://orcid.org/0000-0002-7687-7963"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nicolau, Renata Amadei","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5052958812","display_name":"Cristina Pacheco Soares","orcid":"https://orcid.org/0000-0002-0572-074X","observed_orcids":["https://orcid.org/0000-0002-0572-074X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Soares, Cristina Pacheco","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11566","display_name":"Laser Applications in Dentistry and Medicine","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11566","display_name":"Laser Applications in Dentistry and Medicine","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13869","display_name":"Ocular and Laser Science Research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/laser-irradiation","display_name":"laser irradiation","score":0.8569999933242798},{"id":"https://openalex.org/keywords/led-irradiation","display_name":"LED irradiation","score":0.9259999990463257},{"id":"https://openalex.org/keywords/coherent-light","display_name":"coherent light","score":0.7129999995231628},{"id":"https://openalex.org/keywords/incoherent-light","display_name":"incoherent light","score":0.972000002861023},{"id":"https://openalex.org/keywords/necrosis","display_name":"necrosis","score":0.7829999923706055},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9819999933242798},{"id":"https://openalex.org/keywords/cho-k1-cells","display_name":"CHO-K1 cells","score":0.7049999833106995},{"id":"https://openalex.org/keywords/radiation-dose","display_name":"radiation dose","score":0.5400000214576721},{"id":"https://openalex.org/keywords/810-nm-laser","display_name":"810 nm laser","score":0.7400000095367432},{"id":"https://openalex.org/keywords/cell-viability","display_name":"cell viability","score":0.49799999594688416},{"id":"https://openalex.org/keywords/low-level-laser-therapy","display_name":"low-level laser therapy","score":0.503000020980835},{"id":"https://openalex.org/keywords/phototoxicity","display_name":"phototoxicity","score":0.5799999833106995}],"concepts":[{"id":"https://openalex.org/C520434653","wikidata":"https://www.wikidata.org/wiki/Q38867","display_name":"Laser","level":2,"score":0.5781144499778748},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5666478872299194},{"id":"https://openalex.org/C2987362361","wikidata":"https://www.wikidata.org/wiki/Q38867","display_name":"Laser light","level":3,"score":0.5656879544258118},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.5482665300369263},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.5431536436080933},{"id":"https://openalex.org/C503630168","wikidata":"https://www.wikidata.org/wiki/Q178069","display_name":"Necrosis","level":2,"score":0.5357159376144409},{"id":"https://openalex.org/C78434282","wikidata":"https://www.wikidata.org/wiki/Q11656","display_name":"Diode","level":2,"score":0.5343666672706604},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.47626563906669617},{"id":"https://openalex.org/C176666156","wikidata":"https://www.wikidata.org/wiki/Q25504","display_name":"Light-emitting diode","level":2,"score":0.4618377387523651},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4216134548187256},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3511946201324463},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3212437033653259},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.27949535846710205},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2229488492012024},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2097581923007965},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12012797594070435},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06428983807563782}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/7516658","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Comparative_analysis_of_different_doses_of_coherent_light_laser_and_non-coherent_light_light-emitting_diode_on_cellular_necrosis_and_apoptosis_a_study_in_vitro/7516658","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.7516658","doi":"https://doi.org/10.6084/m9.figshare.7516658","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.7516658","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.7516658.v1","doi":"https://doi.org/10.6084/m9.figshare.7516658.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.7516658.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/7516658","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Comparative_analysis_of_different_doses_of_coherent_light_laser_and_non-coherent_light_light-emitting_diode_on_cellular_necrosis_and_apoptosis_a_study_in_vitro/7516658","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7246000170707703}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2098309715","https://openalex.org/W3029508712","https://openalex.org/W2029062628","https://openalex.org/W2962876509","https://openalex.org/W1820155275","https://openalex.org/W2252567177","https://openalex.org/W2131142788","https://openalex.org/W2086766176","https://openalex.org/W2350261386","https://openalex.org/W3146955885"],"abstract_inverted_index":{"Introduction":[0],"Threshold":[1],"doses":[2,35,63,194,236,295,309],"of":[3,15,36,60,64,103,166,177,195,226,237,242,302],"electromagnetic":[4],"radiation":[5],"can":[6],"initiate":[7],"necrosis":[8,24,152,274],"and":[9,23,27,62,69,76,91,95,114,118,127,131,134,137,156,163,169,174,179,198,202,233,239,244],"apoptosis":[10,22,227,303],"in":[11,110,124,184,189,210,229,272,275,283,293,304],"cells.":[12],"The":[13,101,220],"purpose":[14],"this":[16],"study":[17],"was":[18,108,187],"to":[19,297],"evaluate":[20],"cellular":[21],"immediately":[25,94],"(t0)":[26],"24":[28,96],"hours":[29,97],"(t24)":[30],"after":[31,98],"irradiation":[32,292],"with":[33,50,56,193,234],"different":[34],"coherent":[37],"light":[38,42],"(laser)":[39],"or":[40,53,266,289],"non-coherent":[41],"(LED).":[43],"Methods":[44],"CHO-K1":[45,305],"lineage":[46],"cells":[47,93,105,186,221,228],"were":[48,83],"irradiated":[49],"laser":[51,129,191,235],"(810nm)":[52],"LED":[54,112,135,144,172,212,251,267,290],"(945\u00b120nm),":[55],"24mW,":[57],"contact":[58],"area":[59],"1cm2":[61],"10,":[65,161,196],"20,":[66,162],"30,":[67],"40":[68,113],"50J/cm2":[70,115,199],"for":[71],"300,":[72],"660,":[73],"960,":[74],"1230":[75],"1620s,":[77],"respectively,":[78,120,204],"at":[79,106],"both":[80],"wavelengths.":[81],"Cells":[82],"evaluated":[84],"by":[85],"fluorescence":[86],"microscopy,":[87],"differentiating":[88],"viable,":[89],"apoptotic":[90,185],"necrotic":[92,104],"irradiation.":[99],"Results":[100],"number":[102],"t0":[107],"higher":[109,224],"the":[111,125,143,154,190,211,230,250,261,300],"groups":[116,159],"(86\u00b114":[117],"84\u00b116%":[119],"p":[121],"<0.05),":[122],"than":[123,153],"10":[126,173,238],"20J/cm2":[128,175],"(5\u00b12":[130],"5\u00b13%,":[132],"p<0.05)":[133,139,147],"(5\u00b13":[136],"4\u00b11%,":[138],"conditions.":[140],"At":[141],"t24,":[142],"40J/cm2":[145,213,252],"(80\u00b120%,":[146],"group":[148,192,217,232],"also":[149],"showed":[150],"more":[151],"control":[155,231,262],"lower":[157,258],"dose":[158],"(laser":[160],"30J/cm2":[164,240],"percentage":[165,176,225,259,301],"6\u00b14,":[167],"10\u00b13":[168],"7\u00b13%,":[170],"p<0.05;":[171],"3\u00b11":[178,201],"17\u00b110%,":[180],"p<0.05).":[181],"A":[182],"decrease":[183],"observed":[188],"40,":[197],"(6\u00b14,":[200],"1\u00b11%":[203],"not":[205,215,246,254],"significant),":[206,247],"as":[207,209,281],"well":[208],"(2\u00b12%,":[214],"significant)":[216,255],"versus":[218],"control.":[219],"had":[222,256],"a":[223,257,276,284],"(percentage":[241],"20\u00b11":[243],"20\u00b14%,":[245],"while":[248,307],"only":[249],"(10\u00b110%,":[253],"compared":[260],"group.":[263],"Conclusion":[264],"Laser":[265,288],"stimulation":[268],"promoted":[269],"an":[270],"increase":[271],"cell":[273],"high":[277,308],"energy":[278],"density":[279],"condition":[280],"characterized":[282],"dose-dependent":[285],"inhibition":[286],"therapy.":[287],"infrared":[291],"low":[294],"(up":[296],"20J/cm2)":[298],"reduced":[299],"cells,":[306],"(30J/cm2)":[310],"elevated":[311],"apoptosis.":[312]},"counts_by_year":[],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2024-04-08T00:00:00"}