{"id":"https://openalex.org/W4394112090","doi":"https://doi.org/10.6084/m9.figshare.13161579","title":"Additional file 8 of TRIM25 promotes Capicua degradation independently of ERK in the absence of ATXN1L","display_name":"Additional file 8 of TRIM25 promotes Capicua degradation independently of ERK in the absence of ATXN1L","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W4394112090","doi":"https://doi.org/10.6084/m9.figshare.13161579"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/13161579","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_8_of_TRIM25_promotes_Capicua_degradation_independently_of_ERK_in_the_absence_of_ATXN1L/13161579","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"volume":null,"type":"dataset","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/dataset/Additional_file_8_of_TRIM25_promotes_Capicua_degradation_independently_of_ERK_in_the_absence_of_ATXN1L/13161579","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010462322","display_name":"Derek Wong","orcid":"https://orcid.org/0000-0003-2607-5265","observed_orcids":["https://orcid.org/0000-0003-2607-5265"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wong, Derek","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045721488","display_name":"Lisa Sogerer","orcid":"https://orcid.org/0009-0007-3483-5494","observed_orcids":["https://orcid.org/0009-0007-3483-5494"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sogerer, Lisa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102643577","display_name":"Samantha S. Lee","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lee, Samantha S.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029028791","display_name":"Victor Wong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wong, Victor","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024031776","display_name":"Amy M. Lum","orcid":"https://orcid.org/0000-0002-9236-2492","observed_orcids":["https://orcid.org/0000-0002-9236-2492"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lum, Amy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002431674","display_name":"Adrian Levine","orcid":"https://orcid.org/0000-0003-1048-3360","observed_orcids":["https://orcid.org/0000-0003-1048-3360"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Levine, Adrian B.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070061359","display_name":"Marco A. Marra","orcid":"https://orcid.org/0000-0001-7146-7175","observed_orcids":["https://orcid.org/0000-0001-7146-7175"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marra, Marco A.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5044366354","display_name":"Stephen S. F. Yip","orcid":"https://orcid.org/0000-0002-8514-9861","observed_orcids":["https://orcid.org/0000-0002-8514-9861"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yip, Stephen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8514-9861","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.17810000479221344,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.17810000479221344,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.12870000302791595,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.10670000314712524,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trim25","display_name":"TRIM25","score":1.0},{"id":"https://openalex.org/keywords/capicua","display_name":"Capicua","score":0.9739999771118164},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.5860000252723694},{"id":"https://openalex.org/keywords/differentially-expressed-genes","display_name":"differentially expressed genes","score":0.9210000038146973},{"id":"https://openalex.org/keywords/sirna-knockdown","display_name":"siRNA knockdown","score":0.8880000114440918},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.48899999260902405}],"concepts":[{"id":"https://openalex.org/C2779679103","wikidata":"https://www.wikidata.org/wiki/Q5251805","display_name":"Degradation (telecommunications)","level":2,"score":0.6430777907371521},{"id":"https://openalex.org/C57074206","wikidata":"https://www.wikidata.org/wiki/Q14197552","display_name":"MAPK/ERK pathway","level":3,"score":0.5403720140457153},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.40293920040130615},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.36192023754119873},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.35553210973739624},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.34602123498916626},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16652467846870422},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.1416136920452118},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.11395767331123352}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/13161579","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_8_of_TRIM25_promotes_Capicua_degradation_independently_of_ERK_in_the_absence_of_ATXN1L/13161579","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.13161579","doi":"https://doi.org/10.6084/m9.figshare.13161579","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.13161579","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.13161579.v1","doi":"https://doi.org/10.6084/m9.figshare.13161579.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.13161579.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/13161579","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_8_of_TRIM25_promotes_Capicua_degradation_independently_of_ERK_in_the_absence_of_ATXN1L/13161579","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.504800021648407,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W6977425759","https://openalex.org/W4394560597","https://openalex.org/W4394340383","https://openalex.org/W3097226470","https://openalex.org/W3193884486","https://openalex.org/W2902019710","https://openalex.org/W1974278774","https://openalex.org/W6931832223","https://openalex.org/W2083867561","https://openalex.org/W4241965145"],"abstract_inverted_index":{"Additional":[0],"file":[1],"8:":[2],"Table":[3],"S2":[4],"TRIM25":[5],"differentially":[6],"expressed":[7,10],"genes.":[8],"Differentially":[9],"genes":[11],"identified":[12],"in":[13],"siTRIM25":[14],"vs":[15],"siCtrl":[16],"breast":[17],"carcinoma":[18],"cell":[19],"lines.":[20],"Data":[21],"from":[22],"Walsh":[23],"et":[24],"al.":[25],"study":[26],"[33].":[27]},"counts_by_year":[],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2024-04-08T00:00:00"}