{"id":"https://openalex.org/W4394094846","doi":"https://doi.org/10.6084/m9.figshare.14442954","title":"Additional file 1 of Transcriptomic biomarker pathways associated with death in HIV-infected patients with cryptococcal meningitis","display_name":"Additional file 1 of Transcriptomic biomarker pathways associated with death in HIV-infected patients with cryptococcal meningitis","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W4394094846","doi":"https://doi.org/10.6084/m9.figshare.14442954"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/14442954","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_1_of_Transcriptomic_biomarker_pathways_associated_with_death_in_HIV-infected_patients_with_cryptococcal_meningitis/14442954","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"volume":null,"type":"dataset","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/dataset/Additional_file_1_of_Transcriptomic_biomarker_pathways_associated_with_death_in_HIV-infected_patients_with_cryptococcal_meningitis/14442954","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067952629","display_name":"Irina Vlasova-St. Louis","orcid":"https://orcid.org/0000-0003-0795-4723","observed_orcids":["https://orcid.org/0000-0003-0795-4723"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Louis, Irina Vlasova-St","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0795-4723","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064371778","display_name":"Abdu K Musubire","orcid":"https://orcid.org/0000-0003-2410-5344","observed_orcids":["https://orcid.org/0000-0003-2410-5344"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Musubire, Abdu K.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064975634","display_name":"David B. Meya","orcid":"https://orcid.org/0000-0002-8854-0321","observed_orcids":["https://orcid.org/0000-0002-8854-0321","https://orcid.org/0000-0002-4138-240X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Meya, David B.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055985095","display_name":"Henry W. Nabeta","orcid":"https://orcid.org/0000-0003-0351-507X","observed_orcids":["https://orcid.org/0000-0003-0351-507X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nabeta, Henry W.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060901755","display_name":"Hesham Mohei","orcid":"https://orcid.org/0000-0003-1384-5128","observed_orcids":["https://orcid.org/0000-0003-1384-5128"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohei, Hesham","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027410574","display_name":"David R. Boulware","orcid":"https://orcid.org/0000-0002-4715-0060","observed_orcids":["https://orcid.org/0000-0002-4715-0060"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Boulware, David R.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5064240631","display_name":"Paul R. Bohjanen","orcid":"https://orcid.org/0000-0002-2772-3597","observed_orcids":["https://orcid.org/0000-0002-2772-3597"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bohjanen, Paul R.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12369","display_name":"Pneumocystis jirovecii pneumonia detection and treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cryptococcal-meningitis","display_name":"cryptococcal meningitis","score":0.9670000076293945},{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.7760000228881836},{"id":"https://openalex.org/keywords/transcriptomic-biomarkers","display_name":"transcriptomic biomarkers","score":0.6660000085830688},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.6169999837875366},{"id":"https://openalex.org/keywords/cryptococcal-antigen-titer","display_name":"cryptococcal antigen titer","score":0.6970000267028809},{"id":"https://openalex.org/keywords/cd4-count","display_name":"CD4 count","score":0.8379999995231628},{"id":"https://openalex.org/keywords/immune-reconstitution-inflammatory-syndrome","display_name":"immune reconstitution inflammatory syndrome","score":0.7699999809265137},{"id":"https://openalex.org/keywords/antiretroviral-therapy","display_name":"antiretroviral therapy","score":0.7099999785423279},{"id":"https://openalex.org/keywords/patient-characteristics","display_name":"patient characteristics","score":0.7160000205039978}],"concepts":[{"id":"https://openalex.org/C3019493264","wikidata":"https://www.wikidata.org/wiki/Q1470140","display_name":"Cryptococcal meningitis","level":4,"score":0.8073409795761108},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.6701016426086426},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.6223067045211792},{"id":"https://openalex.org/C2781026528","wikidata":"https://www.wikidata.org/wiki/Q48143","display_name":"Meningitis","level":2,"score":0.6054908633232117},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.5679510831832886},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4209043085575104},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38941115140914917},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38468074798583984},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.34246736764907837},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1388152539730072},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12896466255187988},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.07118144631385803},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.05058932304382324},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.04541638493537903}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/14442954","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_1_of_Transcriptomic_biomarker_pathways_associated_with_death_in_HIV-infected_patients_with_cryptococcal_meningitis/14442954","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.14442954","doi":"https://doi.org/10.6084/m9.figshare.14442954","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.14442954","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"},{"id":"doi:10.6084/m9.figshare.14442954.v1","doi":"https://doi.org/10.6084/m9.figshare.14442954.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.14442954.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/14442954","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Additional_file_1_of_Transcriptomic_biomarker_pathways_associated_with_death_in_HIV-infected_patients_with_cryptococcal_meningitis/14442954","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4394503585","https://openalex.org/W6920852829","https://openalex.org/W4394289389","https://openalex.org/W4400408665","https://openalex.org/W3110780961","https://openalex.org/W2896299997","https://openalex.org/W2156120863","https://openalex.org/W3003654275","https://openalex.org/W4413439764","https://openalex.org/W7046305697"],"abstract_inverted_index":{"Additional":[0],"file":[1],"1.":[2],"Table":[3],"S1.":[4],"Baseline":[5],"(week":[6],"0)":[7],"patient":[8],"characteristics":[9],"for":[10,51,56,70],"each":[11],"group:":[12],"means,":[13],"standard":[14],"deviations":[15],"and":[16,42],"Lower/upper":[17],"95%":[18],"confidence":[19],"interval":[20],"per":[21],"group.":[22],"Assessment":[23],"of":[24],"differences":[25],"in":[26,90,100],"age,":[27],"CD4+":[28],"T":[29],"cell":[30],"count,":[31],"pre-ART":[32,76],"HIV":[33],"viral":[34],"load,":[35],"Serum":[36],"CrAg":[37],"Titers":[38],"(lateral":[39],"flow":[40],"immunoassay),":[41],"sex":[43],"between":[44,59],"groups.":[45],"Wilcoxon":[46],"rank":[47],"sum":[48],"paired":[49],"test":[50],"nonparametric":[52],"data":[53],"was":[54],"used":[55],"the":[57,60],"comparison":[58],"groups":[61],"(JMP14.2":[62],"Pro,":[63],"SAS":[64],"Institute).":[65],"*The":[66],"cut-off":[67],"significance":[68],"level":[69],"all":[71],"P":[72],"values":[73],"<":[74],"0.05.The":[75],"serum":[77],"cryptococcal":[78],"antigen":[79],"titers":[80],"(CrAg),":[81],"as":[82,94],"measured":[83],"by":[84],"LFA":[85],"assay,":[86],"were":[87],"significantly":[88],"higher":[89],"C-IRIS":[91],"survivors\u2019":[92],"group,":[93],"compared":[95],"to":[96],"patients":[97],"who":[98],"died":[99],"earlier":[101],"ART":[102],"study":[103],"arm,":[104],"with":[105],"or":[106],"without":[107],"C-IRIS.":[108]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2024-04-08T00:00:00"}