{"id":"https://openalex.org/W4394013400","doi":"https://doi.org/10.1002/adhm.202400114","title":"Cell Membrane\u2010Camouflaged Chitosan\u2010Polypyrrole Nanogels Co\u2010Deliver Drug and Gene for Targeted Chemotherapy and Bone Metastasis Inhibition of Prostate Cancer","display_name":"Cell Membrane\u2010Camouflaged Chitosan\u2010Polypyrrole Nanogels Co\u2010Deliver Drug and Gene for Targeted Chemotherapy and Bone Metastasis Inhibition of Prostate Cancer","publication_year":2024,"publication_date":"2024-04-06","ids":{"openalex":"https://openalex.org/W4394013400","doi":"https://doi.org/10.1002/adhm.202400114","pmid":"https://pubmed.ncbi.nlm.nih.gov/38581263"},"language":"en","primary_location":{"id":"doi:10.1002/adhm.202400114","doi":"https://doi.org/10.1002/adhm.202400114","is_oa":false,"landing_page_url":"https://doi.org/10.1002/adhm.202400114","pdf_url":null,"source":{"id":"https://openalex.org/S2500736452","display_name":"Advanced Healthcare Materials","issn_l":"2192-2640","issn":["2192-2640","2192-2659"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Healthcare Materials","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101357823","display_name":"Qiuyu Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181326427","display_name":"Donghua University","ror":"https://ror.org/035psfh38","country_code":"CN","type":"education","lineage":["https://openalex.org/I181326427"]},{"id":"https://openalex.org/I4391768076","display_name":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials","ror":"https://ror.org/048nswj43","country_code":"CN","type":"facility","lineage":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiuyu Yu","raw_affiliation_strings":["State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China","institution_ids":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100726291","display_name":"Yue Gao","orcid":"https://orcid.org/0000-0002-3613-1980","observed_orcids":["https://orcid.org/0000-0002-3613-1980"]},"institutions":[{"id":"https://openalex.org/I181326427","display_name":"Donghua University","ror":"https://ror.org/035psfh38","country_code":"CN","type":"education","lineage":["https://openalex.org/I181326427"]},{"id":"https://openalex.org/I4391768076","display_name":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials","ror":"https://ror.org/048nswj43","country_code":"CN","type":"facility","lineage":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yue Gao","raw_affiliation_strings":["State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China","institution_ids":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091505811","display_name":"Waicong Dai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181326427","display_name":"Donghua University","ror":"https://ror.org/035psfh38","country_code":"CN","type":"education","lineage":["https://openalex.org/I181326427"]},{"id":"https://openalex.org/I4391768076","display_name":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials","ror":"https://ror.org/048nswj43","country_code":"CN","type":"facility","lineage":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Waicong Dai","raw_affiliation_strings":["State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China","institution_ids":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100664691","display_name":"Danni Li","orcid":"https://orcid.org/0009-0006-0603-8562","observed_orcids":["https://orcid.org/0009-0006-0603-8562"]},"institutions":[{"id":"https://openalex.org/I181326427","display_name":"Donghua University","ror":"https://ror.org/035psfh38","country_code":"CN","type":"education","lineage":["https://openalex.org/I181326427"]},{"id":"https://openalex.org/I4391768076","display_name":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials","ror":"https://ror.org/048nswj43","country_code":"CN","type":"facility","lineage":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Danni Li","raw_affiliation_strings":["State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China","institution_ids":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100711298","display_name":"Lu Zhang","orcid":"https://orcid.org/0000-0002-1580-6774","observed_orcids":["https://orcid.org/0000-0002-1580-6774"]},"institutions":[{"id":"https://openalex.org/I181326427","display_name":"Donghua University","ror":"https://ror.org/035psfh38","country_code":"CN","type":"education","lineage":["https://openalex.org/I181326427"]},{"id":"https://openalex.org/I4391768076","display_name":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials","ror":"https://ror.org/048nswj43","country_code":"CN","type":"facility","lineage":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lu Zhang","raw_affiliation_strings":["State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China","institution_ids":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032498034","display_name":"Meera Moydeen Abdulhameed","orcid":"https://orcid.org/0000-0001-5394-7933","observed_orcids":["https://orcid.org/0000-0001-5394-7933"]},"institutions":[{"id":"https://openalex.org/I28022161","display_name":"King Saud University","ror":"https://ror.org/02f81g417","country_code":"SA","type":"education","lineage":["https://openalex.org/I28022161"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Meera Moydeen Abdul Hameed","raw_affiliation_strings":["Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451 Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451 Saudi Arabia","institution_ids":["https://openalex.org/I28022161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104705259","display_name":"Rui Guo","orcid":"https://orcid.org/0000-0003-1096-3487","observed_orcids":["https://orcid.org/0000-0003-1096-3487"]},"institutions":[{"id":"https://openalex.org/I181326427","display_name":"Donghua University","ror":"https://ror.org/035psfh38","country_code":"CN","type":"education","lineage":["https://openalex.org/I181326427"]},{"id":"https://openalex.org/I4391768076","display_name":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials","ror":"https://ror.org/048nswj43","country_code":"CN","type":"facility","lineage":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rui Guo","raw_affiliation_strings":["State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China","institution_ids":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100568947","display_name":"Min Liu","orcid":"https://orcid.org/0009-0009-2800-0225","observed_orcids":["https://orcid.org/0009-0009-2800-0225"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210107879","display_name":"Tongren Hospital","ror":"https://ror.org/01r8rcr36","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210107879"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Min Liu","raw_affiliation_strings":["Tongren Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200336 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tongren Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200336 China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210107879"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055489694","display_name":"Xiangyang Shi","orcid":"https://orcid.org/0000-0001-6785-6645","observed_orcids":["https://orcid.org/0000-0001-6785-6645"]},"institutions":[{"id":"https://openalex.org/I181326427","display_name":"Donghua University","ror":"https://ror.org/035psfh38","country_code":"CN","type":"education","lineage":["https://openalex.org/I181326427"]},{"id":"https://openalex.org/I4391768076","display_name":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials","ror":"https://ror.org/048nswj43","country_code":"CN","type":"facility","lineage":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]},{"id":"https://openalex.org/I4405259147","display_name":"Centro de Qu\u00edmica da Madeira","ror":"https://ror.org/01tgdcv71","country_code":"PT","type":"education","lineage":["https://openalex.org/I4405259147","https://openalex.org/I58028834"]},{"id":"https://openalex.org/I58028834","display_name":"Universidade da Madeira","ror":"https://ror.org/0442zbe52","country_code":"PT","type":"education","lineage":["https://openalex.org/I58028834"]}],"countries":["CN","PT"],"is_corresponding":true,"raw_author_name":"Xiangyang Shi","raw_affiliation_strings":["CQM \u2013 Centro de Qu\u00edmica da Madeira University of Madeira Campus Universit\u00e1rio da Penteada  Funchal 9020\u2013105 Portugal","State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CQM \u2013 Centro de Qu\u00edmica da Madeira University of Madeira Campus Universit\u00e1rio da Penteada  Funchal 9020\u2013105 Portugal","institution_ids":["https://openalex.org/I4405259147","https://openalex.org/I58028834"]},{"raw_affiliation_string":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China","institution_ids":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072529270","display_name":"Xueyan Cao","orcid":"https://orcid.org/0000-0003-4366-8943","observed_orcids":["https://orcid.org/0000-0003-4366-8943"]},"institutions":[{"id":"https://openalex.org/I181326427","display_name":"Donghua University","ror":"https://ror.org/035psfh38","country_code":"CN","type":"education","lineage":["https://openalex.org/I181326427"]},{"id":"https://openalex.org/I4391768076","display_name":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials","ror":"https://ror.org/048nswj43","country_code":"CN","type":"facility","lineage":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xueyan Cao","raw_affiliation_strings":["State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China"],"raw_orcid":"https://orcid.org/0000-0003-4366-8943","affiliations":[{"raw_affiliation_string":"State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620 China","institution_ids":["https://openalex.org/I181326427","https://openalex.org/I4391768076"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5055489694","https://openalex.org/A5072529270","https://openalex.org/A5100568947"],"corresponding_institution_ids":["https://openalex.org/I181326427","https://openalex.org/I183067930","https://openalex.org/I4210107879","https://openalex.org/I4391768076","https://openalex.org/I4405259147","https://openalex.org/I58028834"],"apc_list":{"value":4650,"currency":"USD","value_usd":4650},"apc_paid":null,"fwci":2.6258,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.91253644,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"13","issue":"20","first_page":"e2400114","last_page":"e2400114"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9692000150680542,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9692000150680542,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.013799999840557575,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.009100000374019146,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.6629999876022339},{"id":"https://openalex.org/keywords/bone-metastases","display_name":"bone metastasis","score":0.9649999737739563},{"id":"https://openalex.org/keywords/docetaxel","display_name":"docetaxel","score":0.8999999761581421},{"id":"https://openalex.org/keywords/targeted-chemotherapy","display_name":"targeted chemotherapy","score":0.6240000128746033},{"id":"https://openalex.org/keywords/gene-silencing","display_name":"gene silencing","score":0.7839999794960022},{"id":"https://openalex.org/keywords/co-delivery","display_name":"co-delivery","score":0.6869999766349792},{"id":"https://openalex.org/keywords/ph-responsive-drug-release","display_name":"pH-responsive drug release","score":0.8500000238418579},{"id":"https://openalex.org/keywords/pc-3-cells","display_name":"PC-3 cells","score":0.8420000076293945},{"id":"https://openalex.org/keywords/nanoplatforms","display_name":"nanoplatforms","score":0.550000011920929}],"concepts":[{"id":"https://openalex.org/C2779732960","wikidata":"https://www.wikidata.org/wiki/Q408510","display_name":"Chitosan","level":2,"score":0.6501267552375793},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.638574481010437},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.5975739359855652},{"id":"https://openalex.org/C2777232022","wikidata":"https://www.wikidata.org/wiki/Q146230","display_name":"Polypyrrole","level":4,"score":0.597448468208313},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5750411152839661},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.5620105266571045},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.5403026342391968},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.494749516248703},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.48674964904785156},{"id":"https://openalex.org/C15083742","wikidata":"https://www.wikidata.org/wiki/Q261659","display_name":"Nanomedicine","level":3,"score":0.42702776193618774},{"id":"https://openalex.org/C126511603","wikidata":"https://www.wikidata.org/wiki/Q1261145","display_name":"Targeted drug delivery","level":3,"score":0.4226982593536377},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.41048601269721985},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40180447697639465},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3619966506958008},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35462838411331177},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3224870562553406},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3054281771183014},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17520886659622192},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.15636590123176575},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.09850943088531494},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08929577469825745},{"id":"https://openalex.org/C44228677","wikidata":"https://www.wikidata.org/wiki/Q181898","display_name":"Polymerization","level":3,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077143","descriptor_name":"Docetaxel","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000077143","descriptor_name":"Docetaxel","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000078722","descriptor_name":"PC-3 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000080385","descriptor_name":"Nanogels","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":true},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008819","descriptor_name":"Mice, Nude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011758","descriptor_name":"Pyrroles","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011758","descriptor_name":"Pyrroles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D016503","descriptor_name":"Drug Delivery Systems","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D034741","descriptor_name":"RNA, Small Interfering","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D048271","descriptor_name":"Chitosan","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/adhm.202400114","doi":"https://doi.org/10.1002/adhm.202400114","is_oa":false,"landing_page_url":"https://doi.org/10.1002/adhm.202400114","pdf_url":null,"source":{"id":"https://openalex.org/S2500736452","display_name":"Advanced Healthcare Materials","issn_l":"2192-2640","issn":["2192-2640","2192-2659"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Healthcare Materials","raw_type":"journal-article"},{"id":"pmid:38581263","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38581263","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced healthcare materials","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1300220268","display_name":null,"funder_award_id":"RSPD2024R769","funder_id":"https://openalex.org/F4320321145","funder_display_name":"King Saud University"},{"id":"https://openalex.org/G2292308301","display_name":null,"funder_award_id":"23520712500","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"},{"id":"https://openalex.org/G3667673549","display_name":null,"funder_award_id":"52350710203","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G390116814","display_name":null,"funder_award_id":"20DZ2254900","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"},{"id":"https://openalex.org/G6141526659","display_name":null,"funder_award_id":"82172809","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6898580520","display_name":null,"funder_award_id":"U23A2096","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7188269812","display_name":null,"funder_award_id":"21490711500","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"},{"id":"https://openalex.org/G7940229993","display_name":null,"funder_award_id":"23WZ2503300","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321145","display_name":"King Saud University","ror":"https://ror.org/02f81g417"},{"id":"https://openalex.org/F4320321885","display_name":"Science and Technology Commission of Shanghai Municipality","ror":"https://ror.org/03kt66j61"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1971173343","https://openalex.org/W1997442077","https://openalex.org/W2000971605","https://openalex.org/W2032371417","https://openalex.org/W2058509951","https://openalex.org/W2146127775","https://openalex.org/W2589402139","https://openalex.org/W2603066995","https://openalex.org/W2773908247","https://openalex.org/W2949574700","https://openalex.org/W2968492662","https://openalex.org/W2969226420","https://openalex.org/W3023035729","https://openalex.org/W3033841889","https://openalex.org/W3104406294","https://openalex.org/W3128646645","https://openalex.org/W3143970081","https://openalex.org/W3168980009","https://openalex.org/W3197685159","https://openalex.org/W3203975873","https://openalex.org/W3208971891","https://openalex.org/W4282942158","https://openalex.org/W4284882089","https://openalex.org/W4288045715","https://openalex.org/W4297855531","https://openalex.org/W4297918257","https://openalex.org/W4313272764","https://openalex.org/W4361008561","https://openalex.org/W4384819175","https://openalex.org/W4386002426","https://openalex.org/W4386438765","https://openalex.org/W4388129267","https://openalex.org/W4391432352","https://openalex.org/W6600605178","https://openalex.org/W6602680250","https://openalex.org/W6647021394","https://openalex.org/W6728099449","https://openalex.org/W6837478513"],"related_works":["https://openalex.org/W2267485514","https://openalex.org/W4225278553","https://openalex.org/W4300862251","https://openalex.org/W7160711417","https://openalex.org/W3143970081","https://openalex.org/W2979792316","https://openalex.org/W2160107333","https://openalex.org/W4388636194","https://openalex.org/W3214648760","https://openalex.org/W4391450647"],"abstract_inverted_index":{"The":[0,67,147],"development":[1],"of":[2,57,73,134,142,164],"functional":[3],"nanoplatforms":[4],"to":[5,87,122,137],"improve":[6],"the":[7,125,132,138,143],"chemotherapy":[8,51,121,160],"outcome":[9],"and":[10,46,52,83,93,129,161],"inhibit":[11],"distal":[12],"cancer":[13,21,29,60,88,136],"cell":[14,30],"metastasis":[15,55,133],"remains":[16],"an":[17],"extreme":[18],"challenge":[19],"in":[20,61,101],"management.":[22],"In":[23],"this":[24],"work,":[25],"a":[26,62,71,102,113,155],"human-derived":[27],"PC-3":[28,104],"membrane-camouflaged":[31],"chitosan-polypyrrole":[32],"nanogel":[33],"(CH-PPy":[34],"NG)":[35],"platform,":[36],"which":[37],"can":[38],"be":[39,152],"loaded":[40],"with":[41,70],"chemotherapeutic":[42],"drug":[43,80],"docetaxel":[44],"(DTX)":[45],"RANK":[47],"siRNA":[48],"for":[49,91,119,158],"targeted":[50],"gene":[53],"silencing-mediated":[54],"inhibition":[56],"late-stage":[58],"prostate":[59,135,165],"mouse":[63,105],"model,":[64,107],"is":[65,109],"reported.":[66],"prepared":[68],"NGs":[69,150],"size":[72],"155.8":[74],"nm":[75],"show":[76],"good":[77],"biocompatibility,":[78],"pH-responsive":[79],"release":[81],"profile,":[82],"homologous":[84],"targeting":[85],"specificity":[86],"cells,":[89],"allowing":[90],"efficient":[92],"precise":[94],"drug/gene":[95],"co-delivery.":[96],"Through":[97],"in-vivo":[98],"antitumor":[99],"treatment":[100,163],"xenografted":[103],"tumor":[106,126],"it":[108],"shown":[110],"that":[111],"such":[112],"CH-PPy":[114],"NG-facilitated":[115],"co-delivery":[116],"system":[117],"allows":[118],"effective":[120],"slow":[123],"down":[124],"growth":[127],"rate,":[128],"effectively":[130],"inhibits":[131],"bone":[139],"via":[140],"downregulation":[141],"RANK/RANKL":[144],"signaling":[145],"pathway.":[146],"created":[148],"CH-Ppy":[149],"may":[151],"utilized":[153],"as":[154],"promising":[156],"platform":[157],"enhanced":[159],"anti-metastasis":[162],"cancer.":[166]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":18},{"year":2024,"cited_by_count":9}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-04-07T00:00:00"}
