{"id":"https://openalex.org/W4393944752","doi":"https://doi.org/10.3389/fbioe.2024.1376634","title":"Applying knowledge and experience from potato (Solanum tuberosum) to update genetic stability data requirements in the risk assessment for vegetatively propagated biotech crops","display_name":"Applying knowledge and experience from potato (Solanum tuberosum) to update genetic stability data requirements in the risk assessment for vegetatively propagated biotech crops","publication_year":2024,"publication_date":"2024-04-04","ids":{"openalex":"https://openalex.org/W4393944752","doi":"https://doi.org/10.3389/fbioe.2024.1376634","pmid":"https://pubmed.ncbi.nlm.nih.gov/38638325","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11024249"},"language":"en","primary_location":{"id":"doi:10.3389/fbioe.2024.1376634","doi":"https://doi.org/10.3389/fbioe.2024.1376634","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbioe.2024.1376634","pdf_url":"https://www.frontiersin.org/articles/10.3389/fbioe.2024.1376634/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S2595131146","display_name":"Frontiers in Bioengineering and Biotechnology","issn_l":"2296-4185","issn":["2296-4185"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioengineering and Biotechnology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fbioe.2024.1376634/pdf?isPublishedV2=False","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048808333","display_name":"Matthew G. Pence","orcid":"https://orcid.org/0000-0003-2271-789X","observed_orcids":["https://orcid.org/0000-0003-2271-789X"]},"institutions":[{"id":"https://openalex.org/I113311689","display_name":"Simplot (United States)","ror":"https://ror.org/01wg5gq86","country_code":"US","type":"company","lineage":["https://openalex.org/I113311689"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Matthew G. Pence","raw_affiliation_strings":["Simplot Plant Sciences, J. R. Simplot Company, Boise, ID, United States","Simplot Plant Sciences, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Simplot Plant Sciences, J. R. Simplot Company, Boise, ID, United States","institution_ids":["https://openalex.org/I113311689"]},{"raw_affiliation_string":"Simplot Plant Sciences, United States","institution_ids":["https://openalex.org/I113311689"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085510253","display_name":"Muffy Koch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I113311689","display_name":"Simplot (United States)","ror":"https://ror.org/01wg5gq86","country_code":"US","type":"company","lineage":["https://openalex.org/I113311689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Muffy Koch","raw_affiliation_strings":["Simplot Plant Sciences, J. R. Simplot Company, Boise, ID, United States","Simplot Plant Sciences, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Simplot Plant Sciences, J. R. Simplot Company, Boise, ID, United States","institution_ids":["https://openalex.org/I113311689"]},{"raw_affiliation_string":"Simplot Plant Sciences, United States","institution_ids":["https://openalex.org/I113311689"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093738133","display_name":"Jaylee DeMond","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I113311689","display_name":"Simplot (United States)","ror":"https://ror.org/01wg5gq86","country_code":"US","type":"company","lineage":["https://openalex.org/I113311689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jaylee DeMond","raw_affiliation_strings":["Simplot Plant Sciences, J. R. Simplot Company, Boise, ID, United States","Simplot Plant Sciences, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Simplot Plant Sciences, J. R. Simplot Company, Boise, ID, United States","institution_ids":["https://openalex.org/I113311689"]},{"raw_affiliation_string":"Simplot Plant Sciences, United States","institution_ids":["https://openalex.org/I113311689"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065261917","display_name":"Gary W. Rudgers","orcid":"https://orcid.org/0000-0002-4668-8846","observed_orcids":["https://orcid.org/0000-0002-4668-8846"]},"institutions":[{"id":"https://openalex.org/I113311689","display_name":"Simplot (United States)","ror":"https://ror.org/01wg5gq86","country_code":"US","type":"company","lineage":["https://openalex.org/I113311689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary Rudgers","raw_affiliation_strings":["Simplot Plant Sciences, J. R. Simplot Company, Boise, ID, United States","Simplot Plant Sciences, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Simplot Plant Sciences, J. R. Simplot Company, Boise, ID, United States","institution_ids":["https://openalex.org/I113311689"]},{"raw_affiliation_string":"Simplot Plant Sciences, United States","institution_ids":["https://openalex.org/I113311689"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5048808333"],"corresponding_institution_ids":["https://openalex.org/I113311689"],"apc_list":{"value":3295,"currency":"USD","value_usd":3295},"apc_paid":{"value":3295,"currency":"USD","value_usd":3295},"fwci":1.0562,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.73494478,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":97},"biblio":{"volume":"12","issue":null,"first_page":"1376634","last_page":"1376634"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11426","display_name":"Genetically Modified Organisms Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11426","display_name":"Genetically Modified Organisms Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13165","display_name":"Agricultural safety and regulations","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12856","display_name":"Transgenic Plants and Applications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/genetic-stability","display_name":"genetic stability","score":0.9319999814033508},{"id":"https://openalex.org/keywords/vegetative-propagation","display_name":"vegetative propagation","score":0.9390000104904175},{"id":"https://openalex.org/keywords/genetically-modified-crops","display_name":"genetically modified crops","score":0.8560000061988831},{"id":"https://openalex.org/keywords/risk-assessment","display_name":"risk assessment","score":0.75},{"id":"https://openalex.org/keywords/potato","display_name":"potato","score":0.8420000076293945},{"id":"https://openalex.org/keywords/regulatory-data-requirements","display_name":"regulatory data requirements","score":0.8500000238418579},{"id":"https://openalex.org/keywords/safety-assessment","display_name":"safety assessment","score":0.6729999780654907},{"id":"https://openalex.org/keywords/tuber-propagation","display_name":"tuber propagation","score":0.5789999961853027},{"id":"https://openalex.org/keywords/regulatory-science","display_name":"regulatory science","score":0.3089999854564667}],"concepts":[{"id":"https://openalex.org/C2993140171","wikidata":"https://www.wikidata.org/wiki/Q10998","display_name":"Solanum tuberosum","level":2,"score":0.7079251408576965},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.6764470934867859},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5779634714126587},{"id":"https://openalex.org/C137580998","wikidata":"https://www.wikidata.org/wiki/Q235352","display_name":"Crop","level":2,"score":0.49419787526130676},{"id":"https://openalex.org/C188198153","wikidata":"https://www.wikidata.org/wiki/Q1613840","display_name":"Limiting","level":2,"score":0.4274210035800934},{"id":"https://openalex.org/C6557445","wikidata":"https://www.wikidata.org/wiki/Q173113","display_name":"Agronomy","level":1,"score":0.2935112714767456},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.13634595274925232},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fbioe.2024.1376634","doi":"https://doi.org/10.3389/fbioe.2024.1376634","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbioe.2024.1376634","pdf_url":"https://www.frontiersin.org/articles/10.3389/fbioe.2024.1376634/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S2595131146","display_name":"Frontiers in Bioengineering and Biotechnology","issn_l":"2296-4185","issn":["2296-4185"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioengineering and Biotechnology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11024249","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11024249","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11024249/pdf/fbioe-12-1376634.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Bioeng Biotechnol","raw_type":"Text"},{"id":"pmid:38638325","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38638325","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in bioengineering and biotechnology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:d0f0d75d08fc404d820e40aa1835d457","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/d0f0d75d08fc404d820e40aa1835d457","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fbioe.2024.1376634","doi":"https://doi.org/10.3389/fbioe.2024.1376634","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbioe.2024.1376634","pdf_url":"https://www.frontiersin.org/articles/10.3389/fbioe.2024.1376634/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S2595131146","display_name":"Frontiers in Bioengineering and Biotechnology","issn_l":"2296-4185","issn":["2296-4185"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioengineering and Biotechnology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.9208999872207642,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4393944752.pdf","grobid_xml":"https://content.openalex.org/works/W4393944752.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W1971984413","https://openalex.org/W2000929513","https://openalex.org/W2158898879","https://openalex.org/W2289515757","https://openalex.org/W2563515055","https://openalex.org/W2587562657","https://openalex.org/W2591007945","https://openalex.org/W2787264803","https://openalex.org/W2918418208","https://openalex.org/W2960634915","https://openalex.org/W2968732855","https://openalex.org/W2969053862","https://openalex.org/W3092699015","https://openalex.org/W3109899915","https://openalex.org/W3122674033","https://openalex.org/W3128550445","https://openalex.org/W3131917935","https://openalex.org/W4308057522"],"related_works":["https://openalex.org/W3109899915","https://openalex.org/W1822201092","https://openalex.org/W1978207753","https://openalex.org/W2009634959","https://openalex.org/W2150788885","https://openalex.org/W2011920630","https://openalex.org/W2087837312","https://openalex.org/W2793438955","https://openalex.org/W2982094504","https://openalex.org/W2088650321"],"abstract_inverted_index":{"Regulatory":[0],"agencies":[1],"require":[2],"data":[3,83,104,157],"on":[4],"genetic":[5,19,179],"stability":[6,20,82,103,121,180],"as":[7,181],"part":[8,182],"of":[9,21,68,97,114,122,130,142,146,183],"the":[10,18,39,66,94,120,144,184],"safety":[11,33,95,145,167,185],"assessment":[12,96],"for":[13,93,178,187],"biotech":[14,49,100,106,147,190],"crops,":[15,50,59],"even":[16],"though":[17],"a":[22,170],"plant":[23],"is":[24,53,84],"not":[25,62,88,118,161],"necessarily":[26],"an":[27,90],"environmental,":[28,163],"human":[29],"or":[30,126,165],"animal":[31],"health":[32],"concern.":[34],"While":[35],"sexual":[36],"reproduction":[37],"has":[38,109],"potential":[40],"to":[41,75,128,155],"introduce":[42],"genomic":[43],"variation":[44],"in":[45,78],"conventionally":[46],"bred":[47],"and":[48,135],"vegetative":[51,112],"propagation":[52,113],"genetically":[54],"stable.":[55],"In":[56],"vegetatively":[57,98,188],"propagated":[58,99,189],"meiosis":[60],"does":[61,117],"occur":[63],"thus":[64],"limiting":[65],"number":[67],"homologous":[69],"recombination":[70],"events":[71,108],"that":[72,111,159],"could":[73],"lead":[74,127],"chromosomal":[76],"rearrangements":[77],"progeny":[79],"plants.":[80],"Genetic":[81,102],"often,":[85],"but":[86],"should":[87,174],"be,":[89],"automatic":[91],"requirement":[92],"crops.":[101,191],"from":[105,138],"potato":[107,115],"demonstrated":[110],"tubers":[116],"affect":[119],"introduced":[123],"DNA":[124],"sequences":[125],"loss":[129],"trait":[131],"efficacy.":[132],"The":[133],"knowledge":[134],"experience":[136],"gained":[137],"over":[139],"30":[140],"years":[141],"assessing":[143],"crops":[148],"can":[149],"be":[150],"used":[151],"by":[152],"regulatory":[153],"authorities":[154],"eliminate":[156],"requirements":[158,177],"do":[160],"address":[162],"food":[164],"feed":[166],"concerns.":[168],"As":[169],"first":[171],"step,":[172],"regulators":[173],"consider":[175],"removing":[176],"review":[186]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-04-05T00:00:00"}
