{"id":"https://openalex.org/W4393681832","doi":"https://doi.org/10.5281/zenodo.3713308","title":"Dataset related to article \"CXCR3 Identifies Human Naive CD8+ T Cells with Enhanced Effector Differentiation Potential.\"","display_name":"Dataset related to article \"CXCR3 Identifies Human Naive CD8+ T Cells with Enhanced Effector Differentiation Potential.\"","publication_year":2020,"publication_date":"2020-03-17","ids":{"openalex":"https://openalex.org/W4393681832","doi":"https://doi.org/10.5281/zenodo.3713308"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/11999493","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/Dataset_related_to_article_CXCR3_Identifies_Human_Naive_CD8_T_Cells_with_Enhanced_Effector_Differentiation_Potential_/11999493","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"volume":null,"type":"dataset","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/Dataset_related_to_article_CXCR3_Identifies_Human_Naive_CD8_T_Cells_with_Enhanced_Effector_Differentiation_Potential_/11999493","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102903726","display_name":"Giovanni DE SIMONE","orcid":"https://orcid.org/0000-0001-8567-9881","observed_orcids":["https://orcid.org/0000-0001-8567-9881"]},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G, De Simone","raw_affiliation_strings":["Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073353725","display_name":"Emilia Maria Cristina Mazza","orcid":"https://orcid.org/0000-0003-2424-3640","observed_orcids":["https://orcid.org/0000-0003-2424-3640"]},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mazza EMC","raw_affiliation_strings":["Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081079659","display_name":"Antonino Cassotta","orcid":"https://orcid.org/0000-0001-8674-4294","observed_orcids":["https://orcid.org/0000-0001-8674-4294"]},"institutions":[{"id":"https://openalex.org/I4387152247","display_name":"Institute for Research in Biomedicine","ror":"https://ror.org/05gfswd81","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I4387152247","https://openalex.org/I57201433"]},{"id":"https://openalex.org/I57201433","display_name":"Universit\u00e0 della Svizzera italiana","ror":"https://ror.org/03c4atk17","country_code":"CH","type":"education","lineage":["https://openalex.org/I57201433"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Cassotta A","raw_affiliation_strings":["Institute for Research in Biomedicine, Faculty of Biomedical Sciences, USI, 6500 Bellinzona, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Research in Biomedicine, Faculty of Biomedical Sciences, USI, 6500 Bellinzona, Switzerland","institution_ids":["https://openalex.org/I4387152247","https://openalex.org/I57201433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113159379","display_name":"Davydov AN","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1310815967","display_name":"Central European Institute of Technology","ror":"https://ror.org/01p7k1986","country_code":"CZ","type":"education","lineage":["https://openalex.org/I1310815967"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Davydov AN","raw_affiliation_strings":["Central European Institute of Technology, 621 00 Brno, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central European Institute of Technology, 621 00 Brno, Czech Republic","institution_ids":["https://openalex.org/I1310815967"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016638319","display_name":"Mirela Kuka","orcid":"https://orcid.org/0000-0001-9418-1559","observed_orcids":["https://orcid.org/0000-0001-9418-1559"]},"institutions":[{"id":"https://openalex.org/I154387261","display_name":"Vita-Salute San Raffaele University","ror":"https://ror.org/01gmqr298","country_code":"IT","type":"education","lineage":["https://openalex.org/I154387261"]},{"id":"https://openalex.org/I4387155925","display_name":"IRCCS San Raffaele Roma","ror":"https://ror.org/006x48140","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4387155925"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Kuka M","raw_affiliation_strings":["Division of Immunology, Transplantation and Infectious Diseases and Experimental Imaging Center, IRCCS, San Raffaele Scientific Institute and Vita-Salute San Raffaele University, 20132 Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Immunology, Transplantation and Infectious Diseases and Experimental Imaging Center, IRCCS, San Raffaele Scientific Institute and Vita-Salute San Raffaele University, 20132 Milan, Italy","institution_ids":["https://openalex.org/I154387261","https://openalex.org/I4387155925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007404078","display_name":"Veronica Zanon","orcid":"https://orcid.org/0000-0002-6232-1438","observed_orcids":["https://orcid.org/0000-0002-6232-1438"]},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Zanon V","raw_affiliation_strings":["Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030876379","display_name":"De Paoli F","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"F, De Paoli","raw_affiliation_strings":["Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032709519","display_name":"Eloise Scamardella","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Scamardella E","raw_affiliation_strings":["Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027513354","display_name":"Maria Metsger","orcid":"https://orcid.org/0000-0001-9722-0533","observed_orcids":["https://orcid.org/0000-0001-9722-0533"]},"institutions":[{"id":"https://openalex.org/I1310815967","display_name":"Central European Institute of Technology","ror":"https://ror.org/01p7k1986","country_code":"CZ","type":"education","lineage":["https://openalex.org/I1310815967"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Metsger M","raw_affiliation_strings":["Central European Institute of Technology, 621 00 Brno, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central European Institute of Technology, 621 00 Brno, Czech Republic","institution_ids":["https://openalex.org/I1310815967"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019562681","display_name":"Alessandra Roberto","orcid":"https://orcid.org/0000-0001-6615-0026","observed_orcids":["https://orcid.org/0000-0001-6615-0026"]},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A, Roberto","raw_affiliation_strings":["Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008272196","display_name":"Karolina Pilipow","orcid":"https://orcid.org/0000-0001-7095-3112","observed_orcids":["https://orcid.org/0000-0001-7095-3112"]},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Pilipow K","raw_affiliation_strings":["Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015042839","display_name":"Colombo FS","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"FS, Colombo","raw_affiliation_strings":["Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040305422","display_name":"Elena Tenedini","orcid":"https://orcid.org/0000-0003-0285-765X","observed_orcids":["https://orcid.org/0000-0003-0285-765X"]},"institutions":[{"id":"https://openalex.org/I122346577","display_name":"University of Modena and Reggio Emilia","ror":"https://ror.org/02d4c4y02","country_code":"IT","type":"education","lineage":["https://openalex.org/I122346577"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Tenedini E","raw_affiliation_strings":["Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy","institution_ids":["https://openalex.org/I122346577"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077942090","display_name":"Enrico Tagliafico","orcid":"https://orcid.org/0000-0003-0981-2542","observed_orcids":["https://orcid.org/0000-0003-0981-2542"]},"institutions":[{"id":"https://openalex.org/I122346577","display_name":"University of Modena and Reggio Emilia","ror":"https://ror.org/02d4c4y02","country_code":"IT","type":"education","lineage":["https://openalex.org/I122346577"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Tagliafico E","raw_affiliation_strings":["Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy","institution_ids":["https://openalex.org/I122346577"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034721902","display_name":"Luca Gattinoni","orcid":"https://orcid.org/0000-0003-2239-3282","observed_orcids":["https://orcid.org/0000-0003-2239-3282"]},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210149717","display_name":"Center for Cancer Research","ror":"https://ror.org/05bjen692","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4210149717"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gattinoni L","raw_affiliation_strings":["Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892","institution_ids":["https://openalex.org/I4210140884","https://openalex.org/I4210149717"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021041745","display_name":"Domenico Mavilio","orcid":"https://orcid.org/0000-0001-6147-0952","observed_orcids":["https://orcid.org/0000-0001-6147-0952"]},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mavilio D","raw_affiliation_strings":["Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076496892","display_name":"Clelia Peano","orcid":"https://orcid.org/0000-0001-7055-3629","observed_orcids":["https://orcid.org/0000-0001-7055-3629"]},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Peano C","raw_affiliation_strings":["Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048741272","display_name":"DA Price","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79510175","display_name":"Cardiff University","ror":"https://ror.org/03kk7td41","country_code":"GB","type":"education","lineage":["https://openalex.org/I79510175"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"DA, Price","raw_affiliation_strings":["Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff CF14 4XN, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff CF14 4XN, United Kingdom","institution_ids":["https://openalex.org/I79510175"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105039008","display_name":"Singh Sp","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Singh SP","raw_affiliation_strings":["Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020561081","display_name":"Farber Jm","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Farber JM","raw_affiliation_strings":["Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":null,"display_name":"V, Serra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116388","display_name":"Institute of Genetic and Biomedical Research","ror":"https://ror.org/02dr63s31","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210116388","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"V, Serra","raw_affiliation_strings":["IRGB, National Research Council, 09042 Monserrato, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRGB, National Research Council, 09042 Monserrato, Italy","institution_ids":["https://openalex.org/I4210116388","https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044270806","display_name":"Francesco Cucca","orcid":"https://orcid.org/0000-0002-7414-1995","observed_orcids":["https://orcid.org/0000-0002-7414-1995"]},"institutions":[{"id":"https://openalex.org/I4210116388","display_name":"Institute of Genetic and Biomedical Research","ror":"https://ror.org/02dr63s31","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210116388","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Cucca F","raw_affiliation_strings":["IRGB, National Research Council, 09042 Monserrato, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRGB, National Research Council, 09042 Monserrato, Italy","institution_ids":["https://openalex.org/I4210116388","https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046167293","display_name":"Francesco Ferrari","orcid":"https://orcid.org/0000-0002-9811-3753","observed_orcids":["https://orcid.org/0000-0002-9811-3753"]},"institutions":[{"id":"https://openalex.org/I4210114103","display_name":"IFOM","ror":"https://ror.org/02hcsa680","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210114103"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ferrari F","raw_affiliation_strings":["IFOM, FIRC Institute of Molecular Oncology, 20139 Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IFOM, FIRC Institute of Molecular Oncology, 20139 Milan, Italy","institution_ids":["https://openalex.org/I4210114103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063183950","display_name":"Valeria Orr\u00f9","orcid":"https://orcid.org/0000-0002-6047-4625","observed_orcids":["https://orcid.org/0000-0002-6047-4625"]},"institutions":[{"id":"https://openalex.org/I4210116388","display_name":"Institute of Genetic and Biomedical Research","ror":"https://ror.org/02dr63s31","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210116388","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Orr\u00f9 V","raw_affiliation_strings":["IRGB, National Research Council, 09042 Monserrato, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRGB, National Research Council, 09042 Monserrato, Italy","institution_ids":["https://openalex.org/I4210116388","https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102718103","display_name":"Edoardo Fiorillo","orcid":"https://orcid.org/0000-0002-8690-4988","observed_orcids":["https://orcid.org/0000-0002-8690-4988"]},"institutions":[{"id":"https://openalex.org/I4210116388","display_name":"Institute of Genetic and Biomedical Research","ror":"https://ror.org/02dr63s31","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210116388","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Fiorillo E","raw_affiliation_strings":["IRGB, National Research Council, 09042 Monserrato, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRGB, National Research Council, 09042 Monserrato, Italy","institution_ids":["https://openalex.org/I4210116388","https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084119660","display_name":"Matteo Iannacone","orcid":"https://orcid.org/0000-0002-9370-2671","observed_orcids":["https://orcid.org/0000-0002-9370-2671"]},"institutions":[{"id":"https://openalex.org/I154387261","display_name":"Vita-Salute San Raffaele University","ror":"https://ror.org/01gmqr298","country_code":"IT","type":"education","lineage":["https://openalex.org/I154387261"]},{"id":"https://openalex.org/I4387155925","display_name":"IRCCS San Raffaele Roma","ror":"https://ror.org/006x48140","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4387155925"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Iannacone M5,","raw_affiliation_strings":["Division of Immunology, Transplantation and Infectious Diseases and Experimental Imaging Center, IRCCS, San Raffaele Scientific Institute and Vita-Salute San Raffaele University, 20132 Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Immunology, Transplantation and Infectious Diseases and Experimental Imaging Center, IRCCS, San Raffaele Scientific Institute and Vita-Salute San Raffaele University, 20132 Milan, Italy","institution_ids":["https://openalex.org/I154387261","https://openalex.org/I4387155925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060028352","display_name":"Dmitriy M. Chudakov","orcid":"https://orcid.org/0000-0003-0430-790X","observed_orcids":["https://orcid.org/0000-0003-0430-790X","https://orcid.org/0000-0003-2143-9824","https://orcid.org/0000-0001-6273-4008"]},"institutions":[{"id":"https://openalex.org/I1310815967","display_name":"Central European Institute of Technology","ror":"https://ror.org/01p7k1986","country_code":"CZ","type":"education","lineage":["https://openalex.org/I1310815967"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Chudakov DM","raw_affiliation_strings":["Central European Institute of Technology, 621 00 Brno, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central European Institute of Technology, 621 00 Brno, Czech Republic","institution_ids":["https://openalex.org/I1310815967"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047171254","display_name":"Federica Sallusto","orcid":"https://orcid.org/0000-0003-3750-2752","observed_orcids":["https://orcid.org/0000-0003-3750-2752"]},"institutions":[{"id":"https://openalex.org/I4387152247","display_name":"Institute for Research in Biomedicine","ror":"https://ror.org/05gfswd81","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I4387152247","https://openalex.org/I57201433"]},{"id":"https://openalex.org/I57201433","display_name":"Universit\u00e0 della Svizzera italiana","ror":"https://ror.org/03c4atk17","country_code":"CH","type":"education","lineage":["https://openalex.org/I57201433"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Sallusto F","raw_affiliation_strings":["Institute for Research in Biomedicine, Faculty of Biomedical Sciences, USI, 6500 Bellinzona, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Research in Biomedicine, Faculty of Biomedical Sciences, USI, 6500 Bellinzona, Switzerland","institution_ids":["https://openalex.org/I4387152247","https://openalex.org/I57201433"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045159459","display_name":"Enrico Lugli","orcid":"https://orcid.org/0000-0002-1964-7678","observed_orcids":["https://orcid.org/0000-0002-1964-7678"]},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lugli E","raw_affiliation_strings":["Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Humanitas Clinical and Research Center \u2013 IRCCS -, via Manzoni 56, 20089 Rozzano (Mi) - Italy","institution_ids":["https://openalex.org/I4210163047"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":15,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11532","display_name":"Chemokine receptors and signaling","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cxcr3","display_name":"CXCR3","score":0.9990000128746033},{"id":"https://openalex.org/keywords/naive-cd8-t-cells","display_name":"naive CD8+ T cells","score":0.9769999980926514},{"id":"https://openalex.org/keywords/effector-differentiation","display_name":"effector differentiation","score":0.8569999933242798},{"id":"https://openalex.org/keywords/tcr-repertoire","display_name":"T cell receptor repertoire","score":0.6830000281333923},{"id":"https://openalex.org/keywords/chemokine-receptors","display_name":"chemokine receptors","score":0.7289999723434448},{"id":"https://openalex.org/keywords/cd5","display_name":"CD5","score":0.8320000171661377},{"id":"https://openalex.org/keywords/interleukin-2","display_name":"interleukin-2","score":0.890999972820282},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9860000014305115},{"id":"https://openalex.org/keywords/t-cell-heterogeneity","display_name":"T cell heterogeneity","score":0.7570000290870667},{"id":"https://openalex.org/keywords/human-t-cells","display_name":"human T cells","score":0.5239999890327454}],"concepts":[{"id":"https://openalex.org/C25532541","wikidata":"https://www.wikidata.org/wiki/Q655541","display_name":"CXCR3","level":5,"score":0.7394381761550903},{"id":"https://openalex.org/C51785407","wikidata":"https://www.wikidata.org/wiki/Q2627568","display_name":"Effector","level":2,"score":0.7325189113616943},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.48848187923431396},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.42335188388824463},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40329509973526},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.36815521121025085},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.35971003770828247},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35162976384162903},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.18454712629318237},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12336981296539307},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.060289472341537476},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.057136088609695435},{"id":"https://openalex.org/C12823836","wikidata":"https://www.wikidata.org/wiki/Q24720618","display_name":"Chemokine receptor","level":4,"score":0.0},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:figshare.com:article/11999493","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/Dataset_related_to_article_CXCR3_Identifies_Human_Naive_CD8_T_Cells_with_Enhanced_Effector_Differentiation_Potential_/11999493","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:figshare.com:article/11999496","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/Dataset_related_to_article_CXCR3_Identifies_Human_Naive_CD8_T_Cells_with_Enhanced_Effector_Differentiation_Potential_/11999496","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:zenodo.org:3713309","doi":null,"is_oa":true,"landing_page_url":"https://zenodo.org/record/3713309","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"dataset"},{"id":"doi:10.5281/zenodo.3713308","doi":"https://doi.org/10.5281/zenodo.3713308","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.3713308","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"},{"id":"doi:10.5281/zenodo.3713309","doi":"https://doi.org/10.5281/zenodo.3713309","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.3713309","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/11999493","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/Dataset_related_to_article_CXCR3_Identifies_Human_Naive_CD8_T_Cells_with_Enhanced_Effector_Differentiation_Potential_/11999493","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2983661566","https://openalex.org/W3163545923","https://openalex.org/W7099707107","https://openalex.org/W2116633026","https://openalex.org/W1507946465","https://openalex.org/W142023744","https://openalex.org/W2168562934","https://openalex.org/W7160196901","https://openalex.org/W2075436742","https://openalex.org/W2093525495"],"abstract_inverted_index":{"In":[0],"mice,":[1],"the":[2,54,59,144,154],"ability":[3],"of":[4,31,47,58,82,137,157],"naive":[5],"T":[6,160],"(TN)":[7],"cells":[8,93,113,124],"to":[9,101,128],"mount":[10],"an":[11,71],"effector":[12,112,147],"response":[13,100],"correlates":[14],"with":[15,78,85],"TCR":[16],"sensitivity":[17],"for":[18,143],"self-derived":[19],"Ags,":[20],"which":[21,133],"can":[22],"be":[23],"quantified":[24],"indirectly":[25],"by":[26,53,151],"measuring":[27],"surface":[28],"expression":[29],"levels":[30,136],"CD5.":[32,138],"Equivalent":[33],"findings":[34,140],"have":[35],"not":[36],"been":[37],"reported":[38],"previously":[39],"in":[40,99,114,153],"humans.":[41],"We":[42],"identified":[43],"two":[44],"discrete":[45],"subsets":[46],"human":[48,121,158],"CD8+":[49,159],"TN":[50,67,92,123,131],"cells,":[51,132],"defined":[52],"absence":[55],"or":[56],"presence":[57],"chemokine":[60],"receptor":[61],"CXCR3.":[62],"The":[63],"more":[64],"abundant":[65],"CXCR3+":[66,91,122,130],"cell":[68],"subset":[69],"displayed":[70],"effector-like":[72],"transcriptional":[73],"profile":[74],"and":[75,97,107],"expressed":[76,134],"TCRs":[77],"physicochemical":[79],"characteristics":[80],"indicative":[81],"enhanced":[83],"interactions":[84],"peptide-HLA":[86],"class":[87],"I":[88],"Ags.":[89],"Moreover,":[90],"frequently":[94],"produced":[95],"IL-2":[96],"TNF":[98],"nonspecific":[102],"activation":[103],"directly":[104],"ex":[105],"vivo":[106],"differentiated":[108],"readily":[109],"into":[110],"Ag-specific":[111],"vitro.":[115],"Comparative":[116],"analyses":[117],"further":[118],"revealed":[119],"that":[120,146],"were":[125],"transcriptionally":[126],"equivalent":[127],"murine":[129],"high":[135],"These":[139],"provide":[141],"support":[142],"notion":[145],"differentiation":[148],"is":[149],"shaped":[150],"heterogeneity":[152],"preimmune":[155],"repertoire":[156],"cells.":[161]},"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2024-04-03T00:00:00"}