{"id":"https://openalex.org/W4393501880","doi":"https://doi.org/10.1158/1535-7163.25523471","title":"Supplemental Table S6 from The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors","display_name":"Supplemental Table S6 from The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors","publication_year":2024,"publication_date":"2024-04-02","ids":{"openalex":"https://openalex.org/W4393501880","doi":"https://doi.org/10.1158/1535-7163.25523471"},"language":"en","primary_location":{"id":"doi:10.1158/1535-7163.25523471","doi":"https://doi.org/10.1158/1535-7163.25523471","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.25523471","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1535-7163.25523471","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051562975","display_name":"Robert W. Robey","orcid":"https://orcid.org/0000-0002-0857-3650","observed_orcids":["https://orcid.org/0000-0002-0857-3650"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert W. Robey","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0857-3650","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050340296","display_name":"Christina M. Fitzsimmons","orcid":"https://orcid.org/0000-0002-6743-2671","observed_orcids":["https://orcid.org/0000-0002-6743-2671"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christina M. Fitzsimmons","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6743-2671","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048006169","display_name":"Wilfried M. Guiblet","orcid":"https://orcid.org/0000-0001-6319-3418","observed_orcids":["https://orcid.org/0000-0001-6319-3418"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wilfried M. Guiblet","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6319-3418","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026472811","display_name":"William J.E. Frye","orcid":"https://orcid.org/0000-0002-9567-6446","observed_orcids":["https://orcid.org/0000-0002-9567-6446"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William J.E. Frye","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9567-6446","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069124762","display_name":"Jos\u00e9 M. Gonz\u00e1lez Dalmasy","orcid":"https://orcid.org/0009-0007-7906-6342","observed_orcids":["https://orcid.org/0009-0007-7906-6342"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jos\u00e9 M. Gonz\u00e1lez Dalmasy","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0007-7906-6342","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031136248","display_name":"Li Wang","orcid":"https://orcid.org/0000-0002-9176-9194","observed_orcids":["https://orcid.org/0000-0002-9176-9194"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Li Wang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9176-9194","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073845774","display_name":"Drake A. Russell","orcid":"https://orcid.org/0000-0001-9963-916X","observed_orcids":["https://orcid.org/0000-0001-9963-916X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Drake A. Russell","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9963-916X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028049622","display_name":"Lyn Mickley Huff","orcid":"https://orcid.org/0009-0004-6620-808X","observed_orcids":["https://orcid.org/0009-0004-6620-808X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lyn M. Huff","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0004-6620-808X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053124270","display_name":"Andrew J. Perciaccante","orcid":"https://orcid.org/0000-0002-8698-9651","observed_orcids":["https://orcid.org/0000-0002-8698-9651"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew J. Perciaccante","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8698-9651","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071486182","display_name":"Fatima G. Ali-Rahmani","orcid":"https://orcid.org/0009-0007-2429-7661","observed_orcids":["https://orcid.org/0009-0007-2429-7661"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fatima Ali-Rahmani","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0007-2429-7661","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085643279","display_name":"Crystal C. Lipsey","orcid":"https://orcid.org/0000-0003-0494-7624","observed_orcids":["https://orcid.org/0000-0003-0494-7624"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Crystal C. Lipsey","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0494-7624","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045809439","display_name":"Heidi M. Wade","orcid":"https://orcid.org/0000-0002-8030-9272","observed_orcids":["https://orcid.org/0000-0002-8030-9272"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Heidi M. Wade","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8030-9272","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043408742","display_name":"Allison V. Mitchell","orcid":"https://orcid.org/0000-0001-8622-8900","observed_orcids":["https://orcid.org/0000-0001-8622-8900"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Allison V. Mitchell","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8622-8900","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055256152","display_name":"Siddhardha S. Maligireddy","orcid":"https://orcid.org/0000-0003-1143-7788","observed_orcids":["https://orcid.org/0000-0003-1143-7788"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Siddhardha S. Maligireddy","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1143-7788","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085691717","display_name":"David Terrero","orcid":"https://orcid.org/0000-0001-7734-5080","observed_orcids":["https://orcid.org/0000-0001-7734-5080"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Terrero","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7734-5080","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090223620","display_name":"Donna O. Butcher","orcid":"https://orcid.org/0000-0002-2065-8067","observed_orcids":["https://orcid.org/0000-0002-2065-8067"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Donna Butcher","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2065-8067","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067560793","display_name":"Elijah F. Edmondson","orcid":"https://orcid.org/0000-0002-6106-3705","observed_orcids":["https://orcid.org/0000-0002-6106-3705"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elijah F. Edmondson","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6106-3705","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017046869","display_name":"Lisa M. Miller Jenkins","orcid":"https://orcid.org/0000-0003-1245-1338","observed_orcids":["https://orcid.org/0000-0003-1245-1338"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lisa M. Jenkins","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1245-1338","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004309520","display_name":"Tatiana Nikitina","orcid":"https://orcid.org/0009-0007-3482-6408","observed_orcids":["https://orcid.org/0009-0007-3482-6408"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tatiana Nikitina","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0007-3482-6408","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029327520","display_name":"Victor B. Zhurkin","orcid":"https://orcid.org/0000-0002-3589-1523","observed_orcids":["https://orcid.org/0000-0002-3589-1523"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Victor B. Zhurkin","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3589-1523","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004261103","display_name":"Amit Kumar Tiwari","orcid":"https://orcid.org/0000-0002-7427-7155","observed_orcids":["https://orcid.org/0000-0002-7427-7155"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amit K. Tiwari","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7427-7155","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002447157","display_name":"Anthony D. Piscopio","orcid":"https://orcid.org/0009-0004-3611-463X","observed_orcids":["https://orcid.org/0009-0004-3611-463X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anthony D. Piscopio","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0004-3611-463X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007205852","display_name":"Rheem A. Totah","orcid":"https://orcid.org/0000-0003-1664-4874","observed_orcids":["https://orcid.org/0000-0003-1664-4874"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rheem A. Totah","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1664-4874","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013592290","display_name":"Susan Elaine Bates","orcid":"https://orcid.org/0000-0001-6708-0330","observed_orcids":["https://orcid.org/0000-0001-6708-0330"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Susan E. Bates","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6708-0330","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084049190","display_name":"H. Efsun Arda","orcid":"https://orcid.org/0000-0002-5294-2521","observed_orcids":["https://orcid.org/0000-0002-5294-2521"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H. Efsun Arda","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5294-2521","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030334751","display_name":"Michael M. Gottesman","orcid":"https://orcid.org/0000-0001-8908-2097","observed_orcids":["https://orcid.org/0000-0001-8908-2097"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael M. Gottesman","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8908-2097","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5020381456","display_name":"Pedro J. Batista","orcid":"https://orcid.org/0000-0003-1055-2354","observed_orcids":["https://orcid.org/0000-0003-1055-2354"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pedro J. Batista","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1055-2354","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11736","display_name":"Histone Deacetylase Inhibitors Research","score":0.926800012588501,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11736","display_name":"Histone Deacetylase Inhibitors Research","score":0.926800012588501,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.038100000470876694,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mettl7a","display_name":"METTL7A","score":0.9990000128746033},{"id":"https://openalex.org/keywords/mettl7b","display_name":"METTL7B","score":1.0},{"id":"https://openalex.org/keywords/histone-deacetylase-inhibitors","display_name":"histone deacetylase inhibitors","score":0.8460000157356262},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.8989999890327454},{"id":"https://openalex.org/keywords/cross-resistance","display_name":"cross-resistance","score":0.9769999980926514},{"id":"https://openalex.org/keywords/m6a-methyltransferase","display_name":"m6A methyltransferase","score":0.7429999709129333}],"concepts":[{"id":"https://openalex.org/C91965660","wikidata":"https://www.wikidata.org/wiki/Q415875","display_name":"Methyltransferase","level":4,"score":0.7682523727416992},{"id":"https://openalex.org/C2778305200","wikidata":"https://www.wikidata.org/wiki/Q174378","display_name":"Histone deacetylase","level":4,"score":0.6812626719474792},{"id":"https://openalex.org/C2781324293","wikidata":"https://www.wikidata.org/wiki/Q220410","display_name":"Thiol","level":2,"score":0.5929228067398071},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.4506365656852722},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4343298375606537},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.41775715351104736},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.38877642154693604},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3624403774738312},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.313763827085495},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.28341174125671387},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.07229617238044739},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0657975971698761}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1158/1535-7163.25523471","doi":"https://doi.org/10.1158/1535-7163.25523471","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.25523471","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/1535-7163.25523471.v1","doi":"https://doi.org/10.1158/1535-7163.25523471.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.25523471.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/25523471","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplemental_Table_S6_from_The_Methyltransferases_METTL7A_and_METTL7B_Confer_Resistance_to_Thiol-Based_Histone_Deacetylase_Inhibitors/25523471","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1535-7163.25523471","doi":"https://doi.org/10.1158/1535-7163.25523471","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.25523471","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4393497320","https://openalex.org/W4393492174","https://openalex.org/W4393438564","https://openalex.org/W4393497012","https://openalex.org/W7165046963","https://openalex.org/W7148880032","https://openalex.org/W4390342257","https://openalex.org/W4393439085","https://openalex.org/W4393439512","https://openalex.org/W4393859162"],"abstract_inverted_index":{"Supplemental":[0],"Table":[1],"S6":[2],"contains":[3],"information":[4],"about":[5],"the":[6,10],"cross-resistance":[7],"profile":[8],"of":[9],"Vector,":[11],"7A":[12,14],"1-2,":[13],"1-4,":[15],"7B":[16,19],"1-3":[17],"and":[18],"2-2":[20],"cells":[21]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-04-03T00:00:00"}