{"id":"https://openalex.org/W4393385936","doi":"https://doi.org/10.1021/acs.nanolett.4c00451","title":"Plasmonic Annular Nanotrenches with 1 nm Nanogaps for Detection of SARS-CoV-2 Using SERS-Based Immunoassay","display_name":"Plasmonic Annular Nanotrenches with 1 nm Nanogaps for Detection of SARS-CoV-2 Using SERS-Based Immunoassay","publication_year":2024,"publication_date":"2024-04-01","ids":{"openalex":"https://openalex.org/W4393385936","doi":"https://doi.org/10.1021/acs.nanolett.4c00451","pmid":"https://pubmed.ncbi.nlm.nih.gov/38557069"},"language":"en","primary_location":{"id":"doi:10.1021/acs.nanolett.4c00451","doi":"https://doi.org/10.1021/acs.nanolett.4c00451","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.nanolett.4c00451","pdf_url":null,"source":{"id":"https://openalex.org/S143846845","display_name":"Nano Letters","issn_l":"1530-6984","issn":["1530-6984","1530-6992"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nano Letters","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W4393385936"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100732634","display_name":"Sungwoo Lee","orcid":"https://orcid.org/0000-0002-5411-0366","observed_orcids":["https://orcid.org/0000-0002-5411-0366"]},"institutions":[{"id":"https://openalex.org/I146824383","display_name":"Hallym University","ror":"https://ror.org/03sbhge02","country_code":"KR","type":"education","lineage":["https://openalex.org/I146824383"]},{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sungwoo Lee","raw_affiliation_strings":["Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea","Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea","Institute of Basic Science, Sungkyunkwan University, Suwon 16419, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-5411-0366","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea","institution_ids":["https://openalex.org/I146824383"]},{"raw_affiliation_string":"Institute of Basic Science, Sungkyunkwan University, Suwon 16419, Republic of Korea","institution_ids":["https://openalex.org/I848706"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020586343","display_name":"Seonghyeon Lee","orcid":"https://orcid.org/0000-0003-4963-6440","observed_orcids":["https://orcid.org/0000-0003-4963-6440"]},"institutions":[{"id":"https://openalex.org/I146824383","display_name":"Hallym University","ror":"https://ror.org/03sbhge02","country_code":"KR","type":"education","lineage":["https://openalex.org/I146824383"]},{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Seonghyeon Lee","raw_affiliation_strings":["Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea","Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea","Institute of Basic Science, Sungkyunkwan University, Suwon 16419, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea","institution_ids":["https://openalex.org/I146824383"]},{"raw_affiliation_string":"Institute of Basic Science, Sungkyunkwan University, Suwon 16419, Republic of Korea","institution_ids":["https://openalex.org/I848706"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077155104","display_name":"Woongkyu Park","orcid":"https://orcid.org/0000-0002-7743-5286","observed_orcids":["https://orcid.org/0000-0002-7743-5286"]},"institutions":[{"id":"https://openalex.org/I4210117738","display_name":"Korea Photonics Technology Institute","ror":"https://ror.org/022mx4d10","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210117738"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Woongkyu Park","raw_affiliation_strings":["Photonics Energy Components Research Center, Korea Photonics Technology Institute (KOPTI), Gwangju 61007, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-7743-5286","affiliations":[{"raw_affiliation_string":"Photonics Energy Components Research Center, Korea Photonics Technology Institute (KOPTI), Gwangju 61007, Republic of Korea","institution_ids":["https://openalex.org/I4210117738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083813262","display_name":"Soohyun Lee","orcid":"https://orcid.org/0000-0003-1288-3560","observed_orcids":["https://orcid.org/0000-0003-1288-3560"]},"institutions":[{"id":"https://openalex.org/I146824383","display_name":"Hallym University","ror":"https://ror.org/03sbhge02","country_code":"KR","type":"education","lineage":["https://openalex.org/I146824383"]},{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Soohyun Lee","raw_affiliation_strings":["Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea","Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea","Institute of Basic Science, Sungkyunkwan University, Suwon 16419, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0003-1288-3560","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea","institution_ids":["https://openalex.org/I146824383"]},{"raw_affiliation_string":"Institute of Basic Science, Sungkyunkwan University, Suwon 16419, Republic of Korea","institution_ids":["https://openalex.org/I848706"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111233286","display_name":"Sunwoo Kwon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sunwoo Kwon","raw_affiliation_strings":["Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea","institution_ids":["https://openalex.org/I848706"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009265273","display_name":"Myeong Jin Oh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Myeong Jin Oh","raw_affiliation_strings":["Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea","institution_ids":["https://openalex.org/I848706"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091773489","display_name":"MohammadNavid Haddadnezhad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"MohammadNavid Haddadnezhad","raw_affiliation_strings":["Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea","institution_ids":["https://openalex.org/I848706"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045200925","display_name":"Insub Jung","orcid":"https://orcid.org/0000-0003-0827-9280","observed_orcids":["https://orcid.org/0000-0003-0827-9280"]},"institutions":[{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Insub Jung","raw_affiliation_strings":["Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea","Institute of Basic Science, Sungkyunkwan University, Suwon 16419, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0003-0827-9280","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Institute of Basic Science, Sungkyunkwan University, Suwon 16419, Republic of Korea","institution_ids":["https://openalex.org/I848706"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021055535","display_name":"Bohyeon Kim","orcid":"https://orcid.org/0000-0002-8061-0081","observed_orcids":["https://orcid.org/0000-0002-8061-0081"]},"institutions":[{"id":"https://openalex.org/I146824383","display_name":"Hallym University","ror":"https://ror.org/03sbhge02","country_code":"KR","type":"education","lineage":["https://openalex.org/I146824383"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Bohyeon Kim","raw_affiliation_strings":["Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea","institution_ids":["https://openalex.org/I146824383"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116517457","display_name":"Jieun Park","orcid":"https://orcid.org/0009-0003-5595-3271","observed_orcids":["https://orcid.org/0009-0003-5595-3271"]},"institutions":[{"id":"https://openalex.org/I146824383","display_name":"Hallym University","ror":"https://ror.org/03sbhge02","country_code":"KR","type":"education","lineage":["https://openalex.org/I146824383"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jieun Park","raw_affiliation_strings":["Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea","institution_ids":["https://openalex.org/I146824383"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102262210","display_name":"Kyu Sung Shin","orcid":"https://orcid.org/0000-0002-6926-662X","observed_orcids":["https://orcid.org/0000-0002-6926-662X"]},"institutions":[{"id":"https://openalex.org/I146824383","display_name":"Hallym University","ror":"https://ror.org/03sbhge02","country_code":"KR","type":"education","lineage":["https://openalex.org/I146824383"]},{"id":"https://openalex.org/I4210164424","display_name":"Hallym University Chuncheon Sacred Heart Hospital","ror":"https://ror.org/05hwzrf74","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210164424","https://openalex.org/I4210167048"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyu Sung Shin","raw_affiliation_strings":["Laboratory Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon 24253, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon 24253, Republic of Korea","institution_ids":["https://openalex.org/I146824383","https://openalex.org/I4210164424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047981423","display_name":"Hyungdon Lee","orcid":"https://orcid.org/0000-0002-3819-9057","observed_orcids":["https://orcid.org/0000-0002-3819-9057"]},"institutions":[{"id":"https://openalex.org/I146824383","display_name":"Hallym University","ror":"https://ror.org/03sbhge02","country_code":"KR","type":"education","lineage":["https://openalex.org/I146824383"]},{"id":"https://openalex.org/I4210164424","display_name":"Hallym University Chuncheon Sacred Heart Hospital","ror":"https://ror.org/05hwzrf74","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210164424","https://openalex.org/I4210167048"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hyungdon Lee","raw_affiliation_strings":["Department of Internal Medicine, College of Medicine, Hallym University, Chuncheon Sacred Heart Hospital, Chuncheon 24253, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, College of Medicine, Hallym University, Chuncheon Sacred Heart Hospital, Chuncheon 24253, Republic of Korea","institution_ids":["https://openalex.org/I146824383","https://openalex.org/I4210164424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102259838","display_name":"Jun-Sang Yoo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Junsang Yoo","raw_affiliation_strings":["Department of Molecular Biology, Nuturn Science, Seoul 04418, Republic of Korea","Laboratory of Regenerative Medicine for Neurodegenerative Disease, Stand Up Therapeutics, Seoul 04418, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Nuturn Science, Seoul 04418, Republic of Korea","institution_ids":[]},{"raw_affiliation_string":"Laboratory of Regenerative Medicine for Neurodegenerative Disease, Stand Up Therapeutics, Seoul 04418, Republic of Korea","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058157340","display_name":"Won\u2010Keun Kim","orcid":"https://orcid.org/0000-0003-3178-8569","observed_orcids":["https://orcid.org/0000-0003-3178-8569"]},"institutions":[{"id":"https://openalex.org/I146824383","display_name":"Hallym University","ror":"https://ror.org/03sbhge02","country_code":"KR","type":"education","lineage":["https://openalex.org/I146824383"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Won-Keun Kim","raw_affiliation_strings":["Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea","Institute of Medical Research, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea","institution_ids":["https://openalex.org/I146824383"]},{"raw_affiliation_string":"Institute of Medical Research, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea","institution_ids":["https://openalex.org/I146824383"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100406369","display_name":"Sungho Park","orcid":"https://orcid.org/0000-0001-5435-3125","observed_orcids":["https://orcid.org/0000-0001-5435-3125","https://orcid.org/0009-0005-1587-8697"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Sungho Park","raw_affiliation_strings":["Department of Chemistry, Yonsei University, Seoul 03722, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0001-5435-3125","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Yonsei University, Seoul 03722, Republic of Korea","institution_ids":["https://openalex.org/I193775966"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5058157340","https://openalex.org/A5100406369","https://openalex.org/A5102259838"],"corresponding_institution_ids":["https://openalex.org/I146824383","https://openalex.org/I193775966"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":1.8206,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.8508269,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"24","issue":"14","first_page":"4233","last_page":"4240"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10131","display_name":"Gold and Silver Nanoparticles Synthesis and Applications","score":0.8862000107765198,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10131","display_name":"Gold and Silver Nanoparticles Synthesis and Applications","score":0.8862000107765198,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11754","display_name":"SARS-CoV-2 detection and testing","score":0.10989999771118164,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10295","display_name":"Plasmonic and Surface Plasmon Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gold-nanoparticles","display_name":"gold nanoparticles","score":0.7580000162124634},{"id":"https://openalex.org/keywords/nanogap","display_name":"nanogap","score":0.8420000076293945},{"id":"https://openalex.org/keywords/surface-enhanced-raman-scattering","display_name":"surface-enhanced Raman scattering","score":0.9359999895095825},{"id":"https://openalex.org/keywords/sars-cov-2-detection","display_name":"COVID-19 detection","score":0.972000002861023},{"id":"https://openalex.org/keywords/sars-cov-2-spike-protein","display_name":"SARS-CoV-2 spike protein","score":0.906000018119812},{"id":"https://openalex.org/keywords/detection-limit","display_name":"detection limit","score":0.824999988079071}],"concepts":[{"id":"https://openalex.org/C2780420688","wikidata":"https://www.wikidata.org/wiki/Q759183","display_name":"Immunoassay","level":3,"score":0.8557778596878052},{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.7892535328865051},{"id":"https://openalex.org/C169573571","wikidata":"https://www.wikidata.org/wiki/Q466824","display_name":"Raman scattering","level":3,"score":0.5689330101013184},{"id":"https://openalex.org/C110879396","wikidata":"https://www.wikidata.org/wiki/Q58392","display_name":"Plasmon","level":2,"score":0.5400515198707581},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5215380191802979},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5091046690940857},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.46625816822052},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.45581382513046265},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.3839227855205536},{"id":"https://openalex.org/C40003534","wikidata":"https://www.wikidata.org/wiki/Q862228","display_name":"Raman spectroscopy","level":2,"score":0.382224977016449},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.36201298236846924},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.34305539727211},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.22585052251815796},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.19250348210334778},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.10765758156776428},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.08383500576019287},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.06594586372375488},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.06513342261314392},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007118","descriptor_name":"Immunoassay","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1021/acs.nanolett.4c00451","doi":"https://doi.org/10.1021/acs.nanolett.4c00451","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.nanolett.4c00451","pdf_url":null,"source":{"id":"https://openalex.org/S143846845","display_name":"Nano Letters","issn_l":"1530-6984","issn":["1530-6984","1530-6992"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nano Letters","raw_type":"journal-article"},{"id":"pmid:38557069","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38557069","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nano letters","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3922558605","display_name":null,"funder_award_id":"NRF-2021M3H4A4079145","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G4743656934","display_name":null,"funder_award_id":"NRF\u20102022R1A2C2002869","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"}],"funders":[{"id":"https://openalex.org/F4320328359","display_name":"Ministry of Science and ICT, South Korea","ror":"https://ror.org/01wpjm123"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1983660630","https://openalex.org/W2050896599","https://openalex.org/W2093678239","https://openalex.org/W2101863112","https://openalex.org/W2132647165","https://openalex.org/W2154776535","https://openalex.org/W2230620782","https://openalex.org/W2335077566","https://openalex.org/W2527848845","https://openalex.org/W2970591283","https://openalex.org/W2971495366","https://openalex.org/W2994881123","https://openalex.org/W3009912996","https://openalex.org/W3014067025","https://openalex.org/W3032163550","https://openalex.org/W3136487485","https://openalex.org/W3144041213","https://openalex.org/W3184136036","https://openalex.org/W3187229181","https://openalex.org/W3197086477","https://openalex.org/W3200309765","https://openalex.org/W3205604441","https://openalex.org/W4205908103","https://openalex.org/W4213198947","https://openalex.org/W4292062048","https://openalex.org/W4300981111","https://openalex.org/W4308958909","https://openalex.org/W4311171483","https://openalex.org/W4317851305","https://openalex.org/W4320717512","https://openalex.org/W4386100670","https://openalex.org/W4388862400","https://openalex.org/W4388982240"],"related_works":["https://openalex.org/W4392717666","https://openalex.org/W4300489536","https://openalex.org/W4400157786","https://openalex.org/W4281929067","https://openalex.org/W3162428829","https://openalex.org/W7159779918","https://openalex.org/W4395031782","https://openalex.org/W4312082490","https://openalex.org/W4399490481","https://openalex.org/W4396585602"],"abstract_inverted_index":{"This":[0],"study":[1,92],"represents":[2],"the":[3,70,88,118,124],"synthesis":[4],"of":[5,9,28,37,59,62,80,110,115,123],"a":[6,46,91,108,113],"novel":[7],"class":[8],"nanoparticles":[10],"denoted":[11],"as":[12],"annular":[13],"Au":[14],"nanotrenches":[15],"(AANTs).":[16],"AANTs":[17,53],"are":[18],"engineered":[19],"to":[20,129],"possess":[21],"embedded,":[22],"narrow":[23],"circular":[24],"nanogaps":[25],"with":[26,103],"dimensions":[27],"approximately":[29],"1":[30,63],"nm,":[31],"facilitating":[32],"near-field":[33],"focusing":[34],"for":[35,65],"detection":[36,60],"severe":[38],"acute":[39],"respiratory":[40],"syndrome":[41],"coronavirus":[42],"2":[43],"(SARS-CoV-2)":[44],"via":[45],"surface-enhanced":[47],"Raman":[48],"scattering":[49],"(SERS)-based":[50],"immunoassay.":[51],"Notably,":[52],"exhibited":[54],"an":[55,100],"exceedingly":[56],"low":[57],"limit":[58],"(LOD)":[61],"fg/mL":[64],"SARS-CoV-2":[66],"spike":[67],"glycoproteins,":[68],"surpassing":[69],"commercially":[71],"available":[72],"enzyme-linked":[73],"immunosorbent":[74],"assay":[75,135],"(ELISA)":[76],"by":[77],"6":[78],"orders":[79],"magnitude":[81],"(1":[82],"ng/mL":[83],"from":[84],"ELISA).":[85],"To":[86],"assess":[87],"real-world":[89],"applicability,":[90],"was":[93],"conducted":[94],"on":[95],"50":[96],"clinical":[97],"samples":[98],"using":[99],"SERS-based":[101],"immunoassay":[102],"AANTs.":[104],"The":[105],"results":[106],"revealed":[107],"sensitivity":[109],"96%":[111],"and":[112,131],"selectivity":[114],"100%,":[116],"demonstrating":[117],"significantly":[119],"enhanced":[120],"sensing":[121],"capabilities":[122],"proposed":[125],"approach":[126],"in":[127],"comparison":[128],"ELISA":[130],"commercial":[132],"lateral":[133],"flow":[134],"kits.":[136]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":4}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2024-04-02T00:00:00"}