{"id":"https://openalex.org/W4393334974","doi":"https://doi.org/10.1002/ijc.34939","title":"Baseline breast tissue characteristics determine the effect of tamoxifen on mammographic density change","display_name":"Baseline breast tissue characteristics determine the effect of tamoxifen on mammographic density change","publication_year":2024,"publication_date":"2024-03-30","ids":{"openalex":"https://openalex.org/W4393334974","doi":"https://doi.org/10.1002/ijc.34939","pmid":"https://pubmed.ncbi.nlm.nih.gov/38554131"},"language":"en","primary_location":{"id":"doi:10.1002/ijc.34939","doi":"https://doi.org/10.1002/ijc.34939","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ijc.34939","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.34939","source":{"id":"https://openalex.org/S5382288","display_name":"International Journal of Cancer","issn_l":"0020-7136","issn":["0020-7136","1097-0215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Cancer","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.34939","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047591350","display_name":"Marike Gabrielson","orcid":"https://orcid.org/0000-0002-3171-1556","observed_orcids":["https://orcid.org/0000-0002-3171-1556"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Marike Gabrielson","raw_affiliation_strings":["Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-3171-1556","affiliations":[{"raw_affiliation_string":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088964280","display_name":"Mattias Hammarstr\u00f6m","orcid":"https://orcid.org/0000-0001-6608-8867","observed_orcids":["https://orcid.org/0000-0001-6608-8867"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Mattias Hammarstr\u00f6m","raw_affiliation_strings":["Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074942134","display_name":"Jenny Bergqvist","orcid":"https://orcid.org/0000-0002-9875-7946","observed_orcids":["https://orcid.org/0000-0002-9875-7946"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I4210099778","display_name":"Saint G\u00f6ran Hospital","ror":"https://ror.org/00x6s3a91","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210099778"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Jenny Bergqvist","raw_affiliation_strings":["Breast Centre, Department of Surgery Capio St G\u00f6rans Hospital  Stockholm Sweden","Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Breast Centre, Department of Surgery Capio St G\u00f6rans Hospital  Stockholm Sweden","institution_ids":["https://openalex.org/I4210099778"]},{"raw_affiliation_string":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077008266","display_name":"Kristina L\u00e5ng","orcid":"https://orcid.org/0000-0001-9250-1897","observed_orcids":["https://orcid.org/0000-0001-9250-1897"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Kristina L\u00e5ng","raw_affiliation_strings":["Department of Translational Medicine, Diagnostic Radiology, Lund University, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Translational Medicine, Diagnostic Radiology, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016158638","display_name":"Ann H. Rosendahl","orcid":"https://orcid.org/0000-0003-0066-0677","observed_orcids":["https://orcid.org/0000-0003-0066-0677"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Ann H. Rosendahl","raw_affiliation_strings":["Department of Clinical Sciences Lund, Oncology Lund University and Sk\u00e5ne University Hospital  Lund Sweden"],"raw_orcid":"https://orcid.org/0000-0003-0066-0677","affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences Lund, Oncology Lund University and Sk\u00e5ne University Hospital  Lund Sweden","institution_ids":["https://openalex.org/I187531555","https://openalex.org/I4210137844"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027449085","display_name":"Signe Borgquist","orcid":"https://orcid.org/0000-0001-7938-8893","observed_orcids":["https://orcid.org/0000-0001-7938-8893"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I2802335433","display_name":"Aarhus University Hospital","ror":"https://ror.org/040r8fr65","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802335433"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["DK","SE"],"is_corresponding":false,"raw_author_name":"Signe Borgquist","raw_affiliation_strings":["Department of Clinical Sciences Lund, Oncology Lund University and Sk\u00e5ne University Hospital Lund Sweden","Department of Oncology Aarhus University Hospital and Aarhus University  Aarhus Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences Lund, Oncology Lund University and Sk\u00e5ne University Hospital Lund Sweden","institution_ids":["https://openalex.org/I187531555","https://openalex.org/I4210137844"]},{"raw_affiliation_string":"Department of Oncology Aarhus University Hospital and Aarhus University  Aarhus Denmark","institution_ids":["https://openalex.org/I2802335433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020456056","display_name":"Roxanna Hellgren","orcid":"https://orcid.org/0000-0003-4234-8323","observed_orcids":["https://orcid.org/0000-0003-4234-8323"]},"institutions":[{"id":"https://openalex.org/I4210094988","display_name":"Stockholm South General Hospital","ror":"https://ror.org/00ncfk576","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210094988"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Roxanna Hellgren","raw_affiliation_strings":["Department of Radiology S\u00f6dersjukhuset  Stockholm Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology S\u00f6dersjukhuset  Stockholm Sweden","institution_ids":["https://openalex.org/I4210094988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040540995","display_name":"Kamila Czene","orcid":"https://orcid.org/0000-0002-3233-5695","observed_orcids":["https://orcid.org/0000-0002-3233-5695"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Kamila Czene","raw_affiliation_strings":["Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053177403","display_name":"Per N Hall","orcid":"https://orcid.org/0000-0002-5640-9126","observed_orcids":["https://orcid.org/0000-0002-5640-9126"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I4210094988","display_name":"Stockholm South General Hospital","ror":"https://ror.org/00ncfk576","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210094988"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Per Hall","raw_affiliation_strings":["Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden","Department of Oncology, South General Hospital, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Department of Oncology, South General Hospital, Stockholm, Sweden","institution_ids":["https://openalex.org/I4210094988"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5047591350"],"corresponding_institution_ids":["https://openalex.org/I28166907"],"apc_list":{"value":4840,"currency":"USD","value_usd":4840},"apc_paid":{"value":4840,"currency":"USD","value_usd":4840},"fwci":2.3089,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.8859397,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"155","issue":"2","first_page":"339","last_page":"351"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11361","display_name":"Digital Radiography and Breast Imaging","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11361","display_name":"Digital Radiography and Breast Imaging","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tamoxifen","display_name":"tamoxifen","score":1.0},{"id":"https://openalex.org/keywords/breast-density","display_name":"breast density","score":0.9810000061988831},{"id":"https://openalex.org/keywords/breast-composition","display_name":"breast tissue composition","score":0.9300000071525574},{"id":"https://openalex.org/keywords/breast-cancer-chemoprevention","display_name":"breast cancer chemoprevention","score":0.7229999899864197},{"id":"https://openalex.org/keywords/ki-67","display_name":"Ki-67","score":0.8100000023841858},{"id":"https://openalex.org/keywords/oestrogen-receptor","display_name":"oestrogen receptor","score":0.9039999842643738},{"id":"https://openalex.org/keywords/progesterone-receptor","display_name":"progesterone receptor","score":1.0},{"id":"https://openalex.org/keywords/menopausal-status","display_name":"menopausal status","score":0.7170000076293945},{"id":"https://openalex.org/keywords/breast-cancer-risk-prediction","display_name":"breast cancer risk prediction","score":0.5410000085830688}],"concepts":[{"id":"https://openalex.org/C2777176818","wikidata":"https://www.wikidata.org/wiki/Q412178","display_name":"Tamoxifen","level":4,"score":0.7777177095413208},{"id":"https://openalex.org/C12725497","wikidata":"https://www.wikidata.org/wiki/Q810247","display_name":"Baseline (sea)","level":2,"score":0.7145153880119324},{"id":"https://openalex.org/C2909213482","wikidata":"https://www.wikidata.org/wiki/Q17011492","display_name":"MAMMOGRAPHIC DENSITY","level":5,"score":0.6840670108795166},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.622908353805542},{"id":"https://openalex.org/C2780472235","wikidata":"https://www.wikidata.org/wiki/Q324634","display_name":"Mammography","level":4,"score":0.5936053395271301},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.4750349819660187},{"id":"https://openalex.org/C2776067312","wikidata":"https://www.wikidata.org/wiki/Q50429983","display_name":"Antiestrogen","level":5,"score":0.4581926763057709},{"id":"https://openalex.org/C2778001805","wikidata":"https://www.wikidata.org/wiki/Q189961","display_name":"Mammary gland","level":4,"score":0.4455799460411072},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4427233338356018},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4273904263973236},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31853175163269043},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.20065173506736755},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15732288360595703},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000071060","descriptor_name":"Breast Density","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008327","descriptor_name":"Mammography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011960","descriptor_name":"Receptors, Estrogen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011980","descriptor_name":"Receptors, Progesterone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013629","descriptor_name":"Tamoxifen","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D013629","descriptor_name":"Tamoxifen","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D017698","descriptor_name":"Postmenopause","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018931","descriptor_name":"Antineoplastic Agents, Hormonal","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D018931","descriptor_name":"Antineoplastic Agents, Hormonal","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019394","descriptor_name":"Ki-67 Antigen","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D019394","descriptor_name":"Ki-67 Antigen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1002/ijc.34939","doi":"https://doi.org/10.1002/ijc.34939","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ijc.34939","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.34939","source":{"id":"https://openalex.org/S5382288","display_name":"International Journal of Cancer","issn_l":"0020-7136","issn":["0020-7136","1097-0215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Cancer","raw_type":"journal-article"},{"id":"pmid:38554131","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38554131","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of cancer","raw_type":"Journal Article"},{"id":"pmh:oai:lup.lub.lu.se:651e9fd6-cad0-4b68-9ab3-3abd60a7c2e1","doi":null,"is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/651e9fd6-cad0-4b68-9ab3-3abd60a7c2e1","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 0020-7136","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.atira.dk:openaire/a363d1af-46ac-4a69-9d52-99946f76aa5c","doi":null,"is_oa":true,"landing_page_url":"https://pure.au.dk/portal/en/publications/a363d1af-46ac-4a69-9d52-99946f76aa5c","pdf_url":null,"source":null,"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Gabrielson, M, Hammarstr\u00f6m, M, Bergqvist, J, L\u00e5ng, K, Rosendahl, A H, Borgquist, S, Hellgren, R, Czene, K & Hall, P 2024, 'Baseline breast tissue characteristics determine the effect of tamoxifen on mammographic density change', International Journal of Cancer, vol. 155, no. 2, pp. 339-351. https://doi.org/10.1002/ijc.34939","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1002/ijc.34939","doi":"https://doi.org/10.1002/ijc.34939","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ijc.34939","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.34939","source":{"id":"https://openalex.org/S5382288","display_name":"International Journal of Cancer","issn_l":"0020-7136","issn":["0020-7136","1097-0215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1586894495","display_name":null,"funder_award_id":"4\u20102645/2015","funder_id":"https://openalex.org/F4320327237","funder_display_name":"Stockholm l\u00e4ns landsting"},{"id":"https://openalex.org/G224568010","display_name":null,"funder_award_id":"CAN 2015/649","funder_id":"https://openalex.org/F4320321491","funder_display_name":"Cancerfonden"},{"id":"https://openalex.org/G4227779552","display_name":null,"funder_award_id":"CAN 21\u20100454 FE","funder_id":"https://openalex.org/F4320321491","funder_display_name":"Cancerfonden"},{"id":"https://openalex.org/G5056591860","display_name":null,"funder_award_id":"CAN 21-1660","funder_id":"https://openalex.org/F4320321491","funder_display_name":"Cancerfonden"},{"id":"https://openalex.org/G8514379167","display_name":null,"funder_award_id":"E0718301","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"},{"id":"https://openalex.org/G8713312220","display_name":null,"funder_award_id":"CAN 2015/","funder_id":"https://openalex.org/F4320321491","funder_display_name":"Cancerfonden"}],"funders":[{"id":"https://openalex.org/F4320321491","display_name":"Cancerfonden","ror":"https://ror.org/0527jb766"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"},{"id":"https://openalex.org/F4320327237","display_name":"Stockholm l\u00e4ns landsting","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4393334974.pdf","grobid_xml":"https://content.openalex.org/works/W4393334974.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W1543308030","https://openalex.org/W1965442941","https://openalex.org/W1973321155","https://openalex.org/W1983369219","https://openalex.org/W1995388182","https://openalex.org/W1997655151","https://openalex.org/W2013849139","https://openalex.org/W2028170780","https://openalex.org/W2055164611","https://openalex.org/W2070541537","https://openalex.org/W2073877532","https://openalex.org/W2074088213","https://openalex.org/W2075136744","https://openalex.org/W2108184788","https://openalex.org/W2111317895","https://openalex.org/W2111417767","https://openalex.org/W2116208747","https://openalex.org/W2118728607","https://openalex.org/W2119063676","https://openalex.org/W2121548996","https://openalex.org/W2124428587","https://openalex.org/W2131994307","https://openalex.org/W2133722660","https://openalex.org/W2136551853","https://openalex.org/W2137839901","https://openalex.org/W2143486088","https://openalex.org/W2145021397","https://openalex.org/W2151227939","https://openalex.org/W2151340153","https://openalex.org/W2160408484","https://openalex.org/W2161387798","https://openalex.org/W2166969772","https://openalex.org/W2167960011","https://openalex.org/W2170116249","https://openalex.org/W2284424199","https://openalex.org/W2326114887","https://openalex.org/W2330411228","https://openalex.org/W2467142616","https://openalex.org/W2558458383","https://openalex.org/W2789572430","https://openalex.org/W2794467054","https://openalex.org/W2913361606","https://openalex.org/W2992000242","https://openalex.org/W3016216492","https://openalex.org/W3034094929","https://openalex.org/W3080584585","https://openalex.org/W3138246439","https://openalex.org/W3163811744","https://openalex.org/W3176681386","https://openalex.org/W4220982455","https://openalex.org/W4300502931","https://openalex.org/W4313415306","https://openalex.org/W4315927669","https://openalex.org/W4375852712","https://openalex.org/W4385836853"],"related_works":["https://openalex.org/W4315927669","https://openalex.org/W2017581146","https://openalex.org/W2141052110","https://openalex.org/W2608397505","https://openalex.org/W2519316393","https://openalex.org/W2796154413","https://openalex.org/W3090740127","https://openalex.org/W2015199049","https://openalex.org/W6902084784","https://openalex.org/W2060940561"],"abstract_inverted_index":{"Tamoxifen":[0,14],"prevents":[1],"recurrence":[2],"of":[3,50,76,107,147,251],"breast":[4,17,31,84,225],"cancer":[5],"and":[6,20,99,102,104,114,138,144,155,158,164,189,208,235,253],"is":[7,62],"also":[8],"approved":[9],"for":[10,73,96],"preventive,":[11],"risk-reducing,":[12],"therapy.":[13],"alters":[15],"the":[16,22,65,223,231,237],"tissue":[18,32,226],"composition":[19,33],"decreases":[21],"mammographic":[23,128,153],"density.":[24],"We":[25,124],"aimed":[26],"to":[27,45,168,195,215,246],"test":[28],"if":[29],"baseline":[30,89,131,185,206],"influences":[34,230],"tamoxifen-associated":[35,232],"density":[36,119,129,154,179,199,207,233,241],"change.":[37],"This":[38],"biopsy-based":[39],"study":[40,61],"included":[41],"83":[42],"participants":[43],"randomised":[44],"6":[46],"months":[47],"daily":[48],"intake":[49],"placebo,":[51],"20,":[52],"10,":[53],"5,":[54],"2.5,":[55],"or":[56],"1":[57],"mg":[58],"tamoxifen.":[59],"The":[60],"nested":[63],"within":[64],"double-blinded":[66],"tamoxifen":[67,175,196,228],"dose-determination":[68],"trial":[69],"Karolinska":[70],"Mammography":[71],"Project":[72],"Risk":[74],"Prediction":[75],"Breast":[77],"Cancer":[78],"Intervention":[79],"(KARISMA)":[80],"Study.":[81],"Ultrasound-guided":[82],"core-needle":[83],"biopsies":[85],"were":[86,94],"collected":[87],"at":[88,130],"before":[90,227],"starting":[91],"treatment.":[92],"Biopsies":[93],"quantified":[95],"epithelial,":[97],"stromal,":[98],"adipose":[100,142],"distributions,":[101],"epithelial":[103,156,161,187],"stromal":[105,136,145,165,190],"expression":[106,146,213,250],"proliferation":[108],"marker":[109],"Ki67,":[110,162,188],"oestrogen":[111],"receptor":[112,116],"(ER)":[113],"progesterone":[115],"(PR).":[117],"Mammographic":[118],"was":[120,132,181],"measured":[121],"using":[122],"STRATUS.":[123],"found":[125],"that":[126,220,236],"greater":[127,152,178],"positively":[133],"associated":[134,140,182],"with":[135,141,174,183,197],"area":[137,143],"inversely":[139],"ER.":[148],"Premenopausal":[149],"women":[150,172],"had":[151,201],"tissue,":[157],"expressed":[159],"more":[160],"PR,":[163,166],"compared":[167,214],"postmenopausal":[169],"women.":[170],"In":[171],"treated":[173],"(1-20":[176],"mg),":[177],"decrease":[180,200],"higher":[184,205,211],"density,":[186],"PR.":[191,254],"Women":[192],"who":[193],"responded":[194],"a":[198,209],"on":[202],"average":[203],"17%":[204],"2.2-fold":[210],"PR":[212],"non-responders.":[216],"Our":[217],"results":[218],"indicate":[219],"features":[221],"in":[222,240,249],"normal":[224],"exposure":[229],"decrease,":[234],"age-associated":[238],"difference":[239],"change":[242],"may":[243],"be":[244],"related":[245],"age-dependant":[247],"differences":[248],"Ki67":[252]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-03-30T00:00:00"}