{"id":"https://openalex.org/W4393097754","doi":"https://doi.org/10.3310/rdpa1487","title":"Software with artificial intelligence-derived algorithms for analysing CT brain scans in people with a suspected acute stroke: a systematic review and cost-effectiveness analysis","display_name":"Software with artificial intelligence-derived algorithms for analysing CT brain scans in people with a suspected acute stroke: a systematic review and cost-effectiveness analysis","publication_year":2024,"publication_date":"2024-03-01","ids":{"openalex":"https://openalex.org/W4393097754","doi":"https://doi.org/10.3310/rdpa1487","pmid":"https://pubmed.ncbi.nlm.nih.gov/38512017","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11017149"},"language":"en","primary_location":{"id":"doi:10.3310/rdpa1487","doi":"https://doi.org/10.3310/rdpa1487","is_oa":true,"landing_page_url":"https://doi.org/10.3310/rdpa1487","pdf_url":"https://njl-admin.nihr.ac.uk/document/download/2044942","source":{"id":"https://openalex.org/S191206091","display_name":"Health Technology Assessment","issn_l":"1366-5278","issn":["1366-5278","2046-4924","2046-4932"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311817","host_organization_name":"NIHR Journals Library","host_organization_lineage":["https://openalex.org/P4310311817"],"host_organization_lineage_names":["NIHR Journals Library"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health Technology Assessment","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://njl-admin.nihr.ac.uk/document/download/2044942","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074205715","display_name":"Marie E. Westwood","orcid":"https://orcid.org/0000-0002-6257-0653","observed_orcids":["https://orcid.org/0000-0002-6257-0653"]},"institutions":[{"id":"https://openalex.org/I4210088647","display_name":"Kleijnen Systematic Reviews (United Kingdom)","ror":"https://ror.org/004g82f36","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210088647"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Marie Westwood","raw_affiliation_strings":["Kleijnen Systematic Reviews (KSR) Ltd, York, UK"],"raw_orcid":"https://orcid.org/0000-0002-6257-0653","affiliations":[{"raw_affiliation_string":"Kleijnen Systematic Reviews (KSR) Ltd, York, UK","institution_ids":["https://openalex.org/I4210088647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065740152","display_name":"Bram L. T. Ramaekers","orcid":"https://orcid.org/0000-0001-5785-9228","observed_orcids":["https://orcid.org/0000-0001-5785-9228"]},"institutions":[{"id":"https://openalex.org/I2800191616","display_name":"Maastricht University Medical Centre","ror":"https://ror.org/02d9ce178","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800191616"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Bram Ramaekers","raw_affiliation_strings":["Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre (MUMC), Maastricht, Netherlands"],"raw_orcid":"https://orcid.org/0000-0001-5785-9228","affiliations":[{"raw_affiliation_string":"Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre (MUMC), Maastricht, Netherlands","institution_ids":["https://openalex.org/I2800191616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057351979","display_name":"Sabine Elisabeth Grimm","orcid":"https://orcid.org/0000-0002-2175-7999","observed_orcids":["https://orcid.org/0000-0002-2175-7999"]},"institutions":[{"id":"https://openalex.org/I4210088647","display_name":"Kleijnen Systematic Reviews (United Kingdom)","ror":"https://ror.org/004g82f36","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210088647"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sabine Grimm","raw_affiliation_strings":["Kleijnen Systematic Reviews (KSR) Ltd, York, UK"],"raw_orcid":"https://orcid.org/0000-0002-2175-7999","affiliations":[{"raw_affiliation_string":"Kleijnen Systematic Reviews (KSR) Ltd, York, UK","institution_ids":["https://openalex.org/I4210088647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059685514","display_name":"Nigel Armstrong","orcid":"https://orcid.org/0000-0002-7443-4798","observed_orcids":["https://orcid.org/0000-0002-7443-4798"]},"institutions":[{"id":"https://openalex.org/I4210088647","display_name":"Kleijnen Systematic Reviews (United Kingdom)","ror":"https://ror.org/004g82f36","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210088647"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nigel Armstrong","raw_affiliation_strings":["Kleijnen Systematic Reviews (KSR) Ltd, York, UK"],"raw_orcid":"https://orcid.org/0000-0002-7443-4798","affiliations":[{"raw_affiliation_string":"Kleijnen Systematic Reviews (KSR) Ltd, York, UK","institution_ids":["https://openalex.org/I4210088647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080751461","display_name":"Ben F. M. Wijnen","orcid":"https://orcid.org/0000-0001-7993-1905","observed_orcids":["https://orcid.org/0000-0001-7993-1905"]},"institutions":[{"id":"https://openalex.org/I4210088647","display_name":"Kleijnen Systematic Reviews (United Kingdom)","ror":"https://ror.org/004g82f36","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210088647"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ben Wijnen","raw_affiliation_strings":["Kleijnen Systematic Reviews (KSR) Ltd, York, UK"],"raw_orcid":"https://orcid.org/0000-0001-7993-1905","affiliations":[{"raw_affiliation_string":"Kleijnen Systematic Reviews (KSR) Ltd, York, UK","institution_ids":["https://openalex.org/I4210088647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031695309","display_name":"Charlotte Ahmadu","orcid":"https://orcid.org/0000-0001-6420-9071","observed_orcids":["https://orcid.org/0000-0001-6420-9071"]},"institutions":[{"id":"https://openalex.org/I4210088647","display_name":"Kleijnen Systematic Reviews (United Kingdom)","ror":"https://ror.org/004g82f36","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210088647"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Charlotte Ahmadu","raw_affiliation_strings":["Kleijnen Systematic Reviews (KSR) Ltd, York, UK"],"raw_orcid":"https://orcid.org/0000-0001-6420-9071","affiliations":[{"raw_affiliation_string":"Kleijnen Systematic Reviews (KSR) Ltd, York, UK","institution_ids":["https://openalex.org/I4210088647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046117013","display_name":"Shelley de Kock","orcid":"https://orcid.org/0000-0002-3143-806X","observed_orcids":["https://orcid.org/0000-0002-3143-806X"]},"institutions":[{"id":"https://openalex.org/I4210088647","display_name":"Kleijnen Systematic Reviews (United Kingdom)","ror":"https://ror.org/004g82f36","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210088647"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Shelley de Kock","raw_affiliation_strings":["Kleijnen Systematic Reviews (KSR) Ltd, York, UK"],"raw_orcid":"https://orcid.org/0000-0002-3143-806X","affiliations":[{"raw_affiliation_string":"Kleijnen Systematic Reviews (KSR) Ltd, York, UK","institution_ids":["https://openalex.org/I4210088647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051240644","display_name":"Caro Noake","orcid":"https://orcid.org/0000-0003-0329-4772","observed_orcids":["https://orcid.org/0000-0003-0329-4772"]},"institutions":[{"id":"https://openalex.org/I4210088647","display_name":"Kleijnen Systematic Reviews (United Kingdom)","ror":"https://ror.org/004g82f36","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210088647"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Caro Noake","raw_affiliation_strings":["Kleijnen Systematic Reviews (KSR) Ltd, York, UK"],"raw_orcid":"https://orcid.org/0000-0003-0329-4772","affiliations":[{"raw_affiliation_string":"Kleijnen Systematic Reviews (KSR) Ltd, York, UK","institution_ids":["https://openalex.org/I4210088647"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021404933","display_name":"Manuela A. Joore","orcid":"https://orcid.org/0000-0002-5649-6768","observed_orcids":["https://orcid.org/0000-0002-5649-6768"]},"institutions":[{"id":"https://openalex.org/I2800191616","display_name":"Maastricht University Medical Centre","ror":"https://ror.org/02d9ce178","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800191616"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Manuela Joore","raw_affiliation_strings":["Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre (MUMC), Maastricht, Netherlands"],"raw_orcid":"https://orcid.org/0000-0003-2787-7091","affiliations":[{"raw_affiliation_string":"Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre (MUMC), Maastricht, Netherlands","institution_ids":["https://openalex.org/I2800191616"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5074205715"],"corresponding_institution_ids":["https://openalex.org/I4210088647"],"apc_list":null,"apc_paid":null,"fwci":1.2144,"has_fulltext":true,"cited_by_count":18,"citation_normalized_percentile":{"value":0.77536781,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"28","issue":"11","first_page":"1","last_page":"204"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.036400001496076584,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"artificial intelligence","score":0.8330000042915344},{"id":"https://openalex.org/keywords/acute-ischemic-stroke","display_name":"acute ischemic stroke","score":0.7080000042915344},{"id":"https://openalex.org/keywords/large-vessel-occlusion","display_name":"large vessel occlusion","score":0.8550000190734863},{"id":"https://openalex.org/keywords/ct-angiography","display_name":"CT angiography","score":0.7929999828338623},{"id":"https://openalex.org/keywords/mechanical-thrombectomy","display_name":"mechanical thrombectomy","score":0.8140000104904175},{"id":"https://openalex.org/keywords/cost-effectiveness","display_name":"cost-effectiveness","score":0.7099999785423279},{"id":"https://openalex.org/keywords/decision-tree","display_name":"decision tree","score":0.4819999933242798},{"id":"https://openalex.org/keywords/state-transition-model","display_name":"state transition model","score":0.9610000252723694},{"id":"https://openalex.org/keywords/quality-adjusted-life-years","display_name":"quality-adjusted life years","score":0.9449999928474426},{"id":"https://openalex.org/keywords/stroke-triage","display_name":"stroke triage","score":0.3930000066757202},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.4309999942779541},{"id":"https://openalex.org/keywords/national-health-service","display_name":"National Health Service","score":0.6200000047683716},{"id":"https://openalex.org/keywords/viz-ai","display_name":"Viz.ai","score":0.7310000061988831}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6664125919342041},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.5731040835380554},{"id":"https://openalex.org/C3020166492","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Acute stroke","level":3,"score":0.4947895407676697},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4697599411010742},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.4336528182029724},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.43189045786857605},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4145386815071106},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.34534502029418945},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13555994629859924},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08892098069190979},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C2776572282","wikidata":"https://www.wikidata.org/wiki/Q416351","display_name":"Tissue plasminogen activator","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000072226","descriptor_name":"Computed Tomography Angiography","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D000094703","descriptor_name":"Cost-Effectiveness Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003362","descriptor_name":"Cost-Benefit Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013673","descriptor_name":"Technology Assessment, Biomedical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D019057","descriptor_name":"Quality-Adjusted Life Years","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.3310/rdpa1487","doi":"https://doi.org/10.3310/rdpa1487","is_oa":true,"landing_page_url":"https://doi.org/10.3310/rdpa1487","pdf_url":"https://njl-admin.nihr.ac.uk/document/download/2044942","source":{"id":"https://openalex.org/S191206091","display_name":"Health Technology Assessment","issn_l":"1366-5278","issn":["1366-5278","2046-4924","2046-4932"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311817","host_organization_name":"NIHR Journals Library","host_organization_lineage":["https://openalex.org/P4310311817"],"host_organization_lineage_names":["NIHR Journals Library"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health Technology Assessment","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11017149","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11017149","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health Technol Assess","raw_type":"Text"},{"id":"pmid:38512017","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38512017","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health technology assessment (Winchester, England)","raw_type":"Systematic Review"},{"id":"pmh:oai:cris.maastrichtuniversity.nl:openaire/31ca8c40-03a3-4bbd-9a44-eec61d87b04c","doi":null,"is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/31ca8c40-03a3-4bbd-9a44-eec61d87b04c","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Westwood, M, Ramaekers, B, Grimm, S, Armstrong, N, Wijnen, B, Ahmadu, C, de Kock, S, Noake, C & Joore, M 2024, 'Software with artificial intelligence-derived algorithms for analysing CT brain scans in people with a suspected acute stroke : a systematic review and cost-effectiveness analysis', Health Technology Assessment, vol. 28, no. 11, pp. 1-204. https://doi.org/10.3310/RDPA1487","raw_type":"info:eu-repo/semantics/review"},{"id":"pmh:oai:doaj.org/article:eec7fa719ec148008de0ebe295a5ed6c","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/eec7fa719ec148008de0ebe295a5ed6c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Health Technology Assessment, Vol 28, Iss 11 (2024)","raw_type":"article"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire/f0f594ff-6354-408c-badc-ab593cf27d55","doi":null,"is_oa":true,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/f0f594ff-6354-408c-badc-ab593cf27d55","pdf_url":null,"source":{"id":"https://openalex.org/S7407055359","display_name":"Explore Bristol Research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Westwood, M, Ramaekers, B, Grimm, S, Armstrong, N, Wijnen, B, Ahmadu, C, de Kock, S, Noake, C & Joore, M 2024, 'Software with artificial intelligence-derived algorithms for analysing CT brain scans in people with a suspected acute stroke: a systematic review and cost-effectiveness analysis', Health Technology Assessment, vol. 28, no. 11. https://doi.org/10.3310/RDPA1487","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:research-information.bris.ac.uk:publications/f0f594ff-6354-408c-badc-ab593cf27d55","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1983/f0f594ff-6354-408c-badc-ab593cf27d55","pdf_url":null,"source":{"id":"https://openalex.org/S4306400895","display_name":"Bristol Research (University of Bristol)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I36234482","host_organization_name":"University of Bristol","host_organization_lineage":["https://openalex.org/I36234482"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Westwood, M, Ramaekers, B, Grimm, S, Armstrong, N, Wijnen, B, Ahmadu, C, de Kock, S, Noake, C & Joore, M 2024, 'Software with artificial intelligence-derived algorithms for analysing CT brain scans in people with a suspected acute stroke: a systematic review and cost-effectiveness analysis', Health Technology Assessment, vol. 28, no. 11. https://doi.org/10.3310/RDPA1487","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3310/rdpa1487","doi":"https://doi.org/10.3310/rdpa1487","is_oa":true,"landing_page_url":"https://doi.org/10.3310/rdpa1487","pdf_url":"https://njl-admin.nihr.ac.uk/document/download/2044942","source":{"id":"https://openalex.org/S191206091","display_name":"Health Technology Assessment","issn_l":"1366-5278","issn":["1366-5278","2046-4924","2046-4932"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311817","host_organization_name":"NIHR Journals Library","host_organization_lineage":["https://openalex.org/P4310311817"],"host_organization_lineage_names":["NIHR Journals Library"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health Technology Assessment","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"}],"awards":[{"id":"https://openalex.org/G5170199580","display_name":null,"funder_award_id":"NIHR133836","funder_id":"https://openalex.org/F4320334661","funder_display_name":"Health Technology Assessment Programme"},{"id":"https://openalex.org/G7409451471","display_name":null,"funder_award_id":"NIHR133836","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"}],"funders":[{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320319994","display_name":"Department of Health and Social Care","ror":"https://ror.org/03sbpja79"},{"id":"https://openalex.org/F4320334661","display_name":"Health Technology Assessment Programme","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320335362","display_name":"Evidence Synthesis Programme","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4393097754.pdf","grobid_xml":"https://content.openalex.org/works/W4393097754.grobid-xml"},"referenced_works_count":166,"referenced_works":["https://openalex.org/W1593173821","https://openalex.org/W1676366316","https://openalex.org/W1861115201","https://openalex.org/W1966181716","https://openalex.org/W1971348077","https://openalex.org/W1980476279","https://openalex.org/W1990088822","https://openalex.org/W1996802760","https://openalex.org/W2000658246","https://openalex.org/W2016244629","https://openalex.org/W2020488794","https://openalex.org/W2032221360","https://openalex.org/W2036893652","https://openalex.org/W2037399775","https://openalex.org/W2040336929","https://openalex.org/W2048055195","https://openalex.org/W2070083361","https://openalex.org/W2107638293","https://openalex.org/W2114232665","https://openalex.org/W2116308061","https://openalex.org/W2116769108","https://openalex.org/W2119542322","https://openalex.org/W2126727011","https://openalex.org/W2126747154","https://openalex.org/W2130549472","https://openalex.org/W2139621750","https://openalex.org/W2143237216","https://openalex.org/W2157161364","https://openalex.org/W2163915749","https://openalex.org/W2169473952","https://openalex.org/W2171058244","https://openalex.org/W2198398064","https://openalex.org/W2219101814","https://openalex.org/W2277258071","https://openalex.org/W2292308933","https://openalex.org/W2328740020","https://openalex.org/W2341509179","https://openalex.org/W2436069539","https://openalex.org/W2469502808","https://openalex.org/W2511388967","https://openalex.org/W2526978419","https://openalex.org/W2535348557","https://openalex.org/W2544578848","https://openalex.org/W2558092854","https://openalex.org/W2571605156","https://openalex.org/W2598475678","https://openalex.org/W2623455701","https://openalex.org/W2626720699","https://openalex.org/W2731082441","https://openalex.org/W2751124103","https://openalex.org/W2762844398","https://openalex.org/W2767270216","https://openalex.org/W2767776410","https://openalex.org/W2787867590","https://openalex.org/W2791479921","https://openalex.org/W2794265807","https://openalex.org/W2804246295","https://openalex.org/W2885067380","https://openalex.org/W2889969626","https://openalex.org/W2891213421","https://openalex.org/W2891574627","https://openalex.org/W2891934034","https://openalex.org/W2894301500","https://openalex.org/W2896817483","https://openalex.org/W2901459009","https://openalex.org/W2902345415","https://openalex.org/W2906449561","https://openalex.org/W2914040405","https://openalex.org/W2914302179","https://openalex.org/W2917546462","https://openalex.org/W2933842109","https://openalex.org/W2943767668","https://openalex.org/W2944368339","https://openalex.org/W2945807945","https://openalex.org/W2946027146","https://openalex.org/W2952658425","https://openalex.org/W2965073142","https://openalex.org/W2968133585","https://openalex.org/W2974286253","https://openalex.org/W2975101641","https://openalex.org/W2976907604","https://openalex.org/W2976981214","https://openalex.org/W2977021417","https://openalex.org/W2978538842","https://openalex.org/W2981941315","https://openalex.org/W2983649843","https://openalex.org/W2983781575","https://openalex.org/W2984015796","https://openalex.org/W2987338144","https://openalex.org/W2988482861","https://openalex.org/W2992022772","https://openalex.org/W2995143015","https://openalex.org/W2995436502","https://openalex.org/W2995945739","https://openalex.org/W2996221547","https://openalex.org/W2998714401","https://openalex.org/W3008835203","https://openalex.org/W3008956992","https://openalex.org/W3014748407","https://openalex.org/W3015383111","https://openalex.org/W3016429279","https://openalex.org/W3016848704","https://openalex.org/W3020278890","https://openalex.org/W3022142852","https://openalex.org/W3024388808","https://openalex.org/W3025727832","https://openalex.org/W3028402864","https://openalex.org/W3031827868","https://openalex.org/W3033015574","https://openalex.org/W3037360688","https://openalex.org/W3040584329","https://openalex.org/W3040799130","https://openalex.org/W3043796683","https://openalex.org/W3051168136","https://openalex.org/W3080007412","https://openalex.org/W3080136948","https://openalex.org/W3081078899","https://openalex.org/W3083104520","https://openalex.org/W3087761373","https://openalex.org/W3089079906","https://openalex.org/W3092458565","https://openalex.org/W3093843080","https://openalex.org/W3094919265","https://openalex.org/W3098712342","https://openalex.org/W3101308966","https://openalex.org/W3102746191","https://openalex.org/W3103429684","https://openalex.org/W3108582022","https://openalex.org/W3112211694","https://openalex.org/W3115782261","https://openalex.org/W3116932816","https://openalex.org/W3118850490","https://openalex.org/W3119862285","https://openalex.org/W3120873988","https://openalex.org/W3123716077","https://openalex.org/W3128181452","https://openalex.org/W3128257636","https://openalex.org/W3129088433","https://openalex.org/W3134700476","https://openalex.org/W3134833477","https://openalex.org/W3141649711","https://openalex.org/W3144842570","https://openalex.org/W3148691346","https://openalex.org/W3150367798","https://openalex.org/W3153140179","https://openalex.org/W3153843819","https://openalex.org/W3155491570","https://openalex.org/W3158731037","https://openalex.org/W3158840887","https://openalex.org/W3159072155","https://openalex.org/W3159968293","https://openalex.org/W3163018535","https://openalex.org/W3167833869","https://openalex.org/W3172842202","https://openalex.org/W3174493613","https://openalex.org/W3175208866","https://openalex.org/W3175418480","https://openalex.org/W3195201887","https://openalex.org/W3195294569","https://openalex.org/W3195565966","https://openalex.org/W3203487754","https://openalex.org/W4210440929","https://openalex.org/W4242457148","https://openalex.org/W4250315180","https://openalex.org/W4389450158","https://openalex.org/W6759621492"],"related_works":["https://openalex.org/W7215130848","https://openalex.org/W3203487754","https://openalex.org/W4417481788","https://openalex.org/W4416930184","https://openalex.org/W4407320569","https://openalex.org/W4416921885","https://openalex.org/W4224236454","https://openalex.org/W4388995978","https://openalex.org/W7213231592","https://openalex.org/W4390659063"],"abstract_inverted_index":{"Background:":[0],"Artificial":[1],"intelligence-derived":[2,35,79,95,163,186,204,219,440,465,481,521],"software":[3,36,80,187,205,220,441,466,522],"technologies":[4,527],"have":[5],"been":[6],"developed":[7],"that":[8,386,475,524],"are":[9,516],"intended":[10],"to":[11,37,59,67,143,166,195,239,247,264,272,290,298,315,323,346,377,392,432,442,461],"facilitate":[12],"the":[13,28,49,91,145,180,189,211,352,356,374,379,382,387,434,444,463,477,491,494,499,552],"review":[14,39,63,97,165,445,483],"of":[15,32,40,93,98,132,172,191,358,381,389,403,409,416,437,446,479,493,501],"computed":[16,41,99,192,256,447],"tomography":[17,42,100,193,257,307,448],"brain":[18,43,102,449],"scans":[19,44,103,450],"in":[20,45,48,121,179,210,451,533],"patients":[21],"with":[22,112,154],"suspected":[23,158],"stroke.":[24,115,453],"Objectives:":[25],"To":[26],"evaluate":[27,525],"clinical":[29,435,470,534],"and":[30,70,82,137,149,157,224,241,266,292,309,317,411,421,424,555],"cost-effectiveness":[31,348],"using":[33,438],"artificial":[34,78,94,162,185,203,218,359,390,439,464,480,520],"support":[38,443],"acute":[46,452],"stroke":[47,156],"National":[50],"Health":[51],"Service":[52],"setting.":[53],"Methods:":[54],"Twenty-five":[55],"databases":[56],"were":[57,73,177,233,342],"searched":[58],"July":[60],"2021.":[61],"The":[62,85,116,426,454],"process":[64],"included":[65,178],"measures":[66],"minimise":[68],"error":[69],"bias.":[71],"Results":[72],"summarised":[74],"by":[75,354,367],"research":[76],"question,":[77],"technology":[81,206,221],"study":[83,200,338,539],"type.":[84],"health":[86],"economic":[87,455],"analysis":[88],"focused":[89],"on":[90,336,373],"addition":[92,388,478],"software-assisted":[96,164,482],"angiography":[101,194,308],"for":[104,110,126,152,188,214,227,249,274,300,325,413,484,558],"guiding":[105,485],"mechanical":[106,486],"thrombectomy":[107,487],"treatment":[108,488],"decisions":[109,489],"people":[111,153],"an":[113,202],"ischaemic":[114,155],"de":[117],"novo":[118],"model":[119,141],"(developed":[120],"R":[122,124],"Shiny,":[123],"Foundation":[125],"Statistical":[127],"Computing,":[128],"Vienna,":[129],"Austria)":[130],"consisted":[131],"a":[133,138],"decision":[134],"tree":[135],"(short-term)":[136],"state":[139],"transition":[140],"(long-term)":[142],"calculate":[144],"mean":[146],"expected":[147],"costs":[148,408],"quality-adjusted":[150,419],"life-years":[151],"large-vessel":[159,197,231,283,333,394,503],"occlusion":[160,232,395],"comparing":[161],"usual":[167],"care.":[168],"Results:":[169],"A":[170],"total":[171],"22":[173],"studies":[174,183,341,515],"(30":[175],"publications)":[176],"review;":[181],"18/22":[182],"concerned":[184],"interpretation":[190],"detect":[196,393],"occlusion.":[198],"No":[199],"evaluated":[201],"used":[207],"as":[208,528,542],"specified":[209],"inclusion":[212],"criteria":[213],"this":[215,505],"assessment.":[216],"For":[217],"alone,":[222],"sensitivity":[223,380,492],"specificity":[225],"estimates":[226],"proximal":[228],"anterior":[229],"circulation":[230],"95.4%":[234],"(95%":[235,243,260,268,286,294,311,319],"confidence":[236,244,261,269,287,295,312,320],"interval":[237,245,262,270,288,296,313,321],"92.7%":[238],"97.1%)":[240],"79.4%":[242],"75.8%":[246],"82.6%)":[248],"Rapid":[250],"(iSchemaView,":[251],"Menlo":[252],"Park,":[253],"CA,":[254],"USA)":[255,282],"angiography,":[258],"91.2%":[259],"77.0%":[263],"97.0%)":[265],"85.0":[267],"64.0%":[271],"94.8%)":[273],"Viz":[275],"LVO":[276],"(Viz.ai,":[277],"Inc.,":[278],"San":[279],"Fransisco,":[280],"VA,":[281],"occlusion,":[284,334],"83.8%":[285],"77.3%":[289],"88.7%)":[291],"95.7%":[293],"91.0%":[297],"98.0%)":[299],"Brainomix":[301],"(Brainomix":[302],"Ltd,":[303],"Oxford,":[304],"UK)":[305],"e-computed":[306],"98.1%":[310],"94.5%":[314],"99.3%)":[316,324],"98.2%":[318],"95.5%":[322],"Avicenna":[326],"CINA":[327],"(Avicenna":[328],"AI,":[329],"La":[330],"Ciotat,":[331],"France)":[332],"based":[335,372],"one":[337],"each.":[339],"These":[340],"not":[343,430,458],"considered":[344,508],"appropriate":[345],"inform":[347,378],"modelling":[349],"but":[350],"formed":[351],"basis":[353],"which":[355],"accuracy":[357],"intelligence":[360,391],"plus":[361],"human":[362],"reader":[363],"could":[364],"be":[365,507,531],"elicited":[366],"expert":[368,375],"opinion.":[369],"Probabilistic":[370],"analyses":[371,456],"elicitation":[376],"diagnostic":[383,495],"pathway":[384,496],"indicated":[385,474],"is":[396,429,540],"potentially":[397],"more":[398,405],"effective":[399],"(quality-adjusted":[400],"life-year":[401,420],"gain":[402],"0.003),":[404],"costly":[406],"(increased":[407],"\u00a38.61)":[410],"cost-effective":[412],"willingness-to-pay":[414],"thresholds":[415],"\u00a33380":[417],"per":[418],"higher.":[422],"Limitations":[423],"conclusions:":[425],"available":[427],"evidence":[428,460],"suitable":[431],"determine":[433],"effectiveness":[436],"did":[457],"provide":[459],"prefer":[462],"strategy":[467],"over":[468],"current":[469],"practice.":[471,535],"However,":[472],"results":[473],"if":[476],"increased":[490],"(i.e.":[497],"reduced":[498],"proportion":[500],"undetected":[502],"occlusions),":[504],"may":[506],"cost-effective.":[509],"Future":[510],"work:":[511],"Large,":[512],"preferably":[513],"multicentre,":[514],"needed":[517],"(for":[518],"all":[519],"technologies)":[523],"these":[526],"they":[529],"would":[530],"implemented":[532],"Study":[536],"registration:":[537],"This":[538],"registered":[541],"PROSPERO":[543],"CRD42021269609.":[544],"Funding:":[545],";":[546],"Vol.":[547],"28,":[548],"No.":[549],"11.":[550],"See":[551],"NIHR":[553],"Funding":[554],"Awards":[556],"website":[557],"further":[559],"award":[560],"information.":[561]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2024-03-23T00:00:00"}