{"id":"https://openalex.org/W4393092048","doi":"https://doi.org/10.3389/fnagi.2024.1390324","title":"Bibliometric analysis of PTEN in neurodevelopment and neurodegeneration","display_name":"Bibliometric analysis of PTEN in neurodevelopment and neurodegeneration","publication_year":2024,"publication_date":"2024-03-22","ids":{"openalex":"https://openalex.org/W4393092048","doi":"https://doi.org/10.3389/fnagi.2024.1390324","pmid":"https://pubmed.ncbi.nlm.nih.gov/38586827","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10995293"},"language":"en","primary_location":{"id":"doi:10.3389/fnagi.2024.1390324","doi":"https://doi.org/10.3389/fnagi.2024.1390324","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnagi.2024.1390324","pdf_url":"https://www.frontiersin.org/articles/10.3389/fnagi.2024.1390324/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S118428158","display_name":"Frontiers in Aging Neuroscience","issn_l":"1663-4365","issn":["1663-4365"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Aging Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fnagi.2024.1390324/pdf?isPublishedV2=False","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100356842","display_name":"Yun Zhang","orcid":"https://orcid.org/0000-0003-2773-9086","observed_orcids":["https://orcid.org/0000-0003-2773-9086"]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yun Zhang","raw_affiliation_strings":["Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha, Hunan, China","Department of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha, Hunan, China","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"Department of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China","institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210153856"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068792727","display_name":"Ya-ting Tan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ya-ting Tan","raw_affiliation_strings":["Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha, Hunan, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103261317","display_name":"Meijuan Wang","orcid":"https://orcid.org/0000-0002-3926-9125","observed_orcids":["https://orcid.org/0000-0002-3926-9125","https://orcid.org/0000-0003-2579-8736"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mei-juan Wang","raw_affiliation_strings":["Medical Imaging Center, Qingdao West Coast New District People's Hospital, Qingdao, Shandong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Imaging Center, Qingdao West Coast New District People's Hospital, Qingdao, Shandong, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lan Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lan Li","raw_affiliation_strings":["Department of Pathology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China","institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210153856","https://openalex.org/I4210159865"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ju-fang Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ju-fang Huang","raw_affiliation_strings":["Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha, Hunan, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077104116","display_name":"Shu\u2010chao Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shu-chao Wang","raw_affiliation_strings":["Center for Medical Research, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Medical Research, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China","institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210153856","https://openalex.org/I4210159865"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5077104116"],"corresponding_institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210153856","https://openalex.org/I4210159865"],"apc_list":{"value":3295,"currency":"USD","value_usd":3295},"apc_paid":{"value":3295,"currency":"USD","value_usd":3295},"fwci":2.9553,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.91852326,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"16","issue":null,"first_page":"1390324","last_page":"1390324"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10102","display_name":"scientometrics and bibliometrics research","score":0.4652999937534332,"subfield":{"id":"https://openalex.org/subfields/3309","display_name":"Library and Information Sciences"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10102","display_name":"scientometrics and bibliometrics research","score":0.4652999937534332,"subfield":{"id":"https://openalex.org/subfields/3309","display_name":"Library and Information Sciences"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11772","display_name":"Genetics and Neurodevelopmental Disorders","score":0.24240000545978546,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.05829999968409538,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pten","display_name":"PTEN","score":0.9990000128746033},{"id":"https://openalex.org/keywords/brain-development","display_name":"brain development","score":0.878000020980835},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.9990000128746033},{"id":"https://openalex.org/keywords/neurogenesis","display_name":"neurogenesis","score":0.75},{"id":"https://openalex.org/keywords/synaptogenesis","display_name":"synaptogenesis","score":0.9909999966621399},{"id":"https://openalex.org/keywords/neuronal-survival","display_name":"neuronal survival","score":0.8939999938011169},{"id":"https://openalex.org/keywords/neurological-disorders","display_name":"neurological disorders","score":0.6499999761581421},{"id":"https://openalex.org/keywords/stroke","display_name":"stroke","score":0.796999990940094},{"id":"https://openalex.org/keywords/seizures","display_name":"seizures","score":0.9190000295639038},{"id":"https://openalex.org/keywords/autism-spectrum-disorder","display_name":"autism spectrum disorder","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tumor-suppression","display_name":"tumor suppression","score":0.6320000290870667},{"id":"https://openalex.org/keywords/research-trends","display_name":"research trends","score":0.7409999966621399},{"id":"https://openalex.org/keywords/research-hotspots","display_name":"research hotspots","score":0.7049999833106995}],"concepts":[{"id":"https://openalex.org/C2777609662","wikidata":"https://www.wikidata.org/wiki/Q416356","display_name":"PTEN","level":4,"score":0.9699904918670654},{"id":"https://openalex.org/C2779549131","wikidata":"https://www.wikidata.org/wiki/Q83167294","display_name":"Tensin","level":5,"score":0.9087752103805542},{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.6411659121513367},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6161444187164307},{"id":"https://openalex.org/C65232495","wikidata":"https://www.wikidata.org/wiki/Q1813773","display_name":"Synaptogenesis","level":2,"score":0.5519192814826965},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4882338345050812},{"id":"https://openalex.org/C2776925932","wikidata":"https://www.wikidata.org/wiki/Q1755122","display_name":"Neurodegeneration","level":3,"score":0.46003541350364685},{"id":"https://openalex.org/C545706735","wikidata":"https://www.wikidata.org/wiki/Q9404","display_name":"Nervous system","level":2,"score":0.45466840267181396},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3903151750564575},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3313791751861572},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.25479966402053833},{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.2355080544948578},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18182504177093506},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.17813149094581604},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13765603303909302}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fnagi.2024.1390324","doi":"https://doi.org/10.3389/fnagi.2024.1390324","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnagi.2024.1390324","pdf_url":"https://www.frontiersin.org/articles/10.3389/fnagi.2024.1390324/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S118428158","display_name":"Frontiers in Aging Neuroscience","issn_l":"1663-4365","issn":["1663-4365"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Aging Neuroscience","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10995293","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10995293","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10995293/pdf/fnagi-16-1390324.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Aging Neurosci","raw_type":"Text"},{"id":"pmid:38586827","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38586827","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in aging neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:1b3f29b9a2154eb28c6e68ceb3627893","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/1b3f29b9a2154eb28c6e68ceb3627893","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Aging Neuroscience, Vol 16 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fnagi.2024.1390324","doi":"https://doi.org/10.3389/fnagi.2024.1390324","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnagi.2024.1390324","pdf_url":"https://www.frontiersin.org/articles/10.3389/fnagi.2024.1390324/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S118428158","display_name":"Frontiers in Aging Neuroscience","issn_l":"1663-4365","issn":["1663-4365"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Aging Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4043000042438507}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1741444709","display_name":null,"funder_award_id":"82101126","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321514","display_name":"Central South University","ror":"https://ror.org/00f1zfq44"},{"id":"https://openalex.org/F4320335740","display_name":"Xiangya Hospital, Central South University","ror":"https://ror.org/05akvb491"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4393092048.pdf","grobid_xml":"https://content.openalex.org/works/W4393092048.grobid-xml"},"referenced_works_count":85,"referenced_works":["https://openalex.org/W1543788907","https://openalex.org/W1701569822","https://openalex.org/W1980155382","https://openalex.org/W1996644622","https://openalex.org/W2004538934","https://openalex.org/W2037554299","https://openalex.org/W2063107522","https://openalex.org/W2069292824","https://openalex.org/W2083004303","https://openalex.org/W2084080552","https://openalex.org/W2088487932","https://openalex.org/W2092119894","https://openalex.org/W2094215712","https://openalex.org/W2105989397","https://openalex.org/W2109610561","https://openalex.org/W2120856082","https://openalex.org/W2134319771","https://openalex.org/W2154087863","https://openalex.org/W2160368371","https://openalex.org/W2266810164","https://openalex.org/W2507606727","https://openalex.org/W2590621600","https://openalex.org/W2640197197","https://openalex.org/W2755823196","https://openalex.org/W2757084251","https://openalex.org/W2803681151","https://openalex.org/W2809999132","https://openalex.org/W2911075837","https://openalex.org/W2924739293","https://openalex.org/W2969666584","https://openalex.org/W2980725598","https://openalex.org/W2982244302","https://openalex.org/W2983686695","https://openalex.org/W2984955289","https://openalex.org/W2990139677","https://openalex.org/W3045827442","https://openalex.org/W3118500963","https://openalex.org/W3123065457","https://openalex.org/W3128667968","https://openalex.org/W3129475217","https://openalex.org/W3132351233","https://openalex.org/W3134617337","https://openalex.org/W3158830516","https://openalex.org/W3169287008","https://openalex.org/W3178401932","https://openalex.org/W3205242879","https://openalex.org/W3213144231","https://openalex.org/W3217520255","https://openalex.org/W3217652012","https://openalex.org/W4206627355","https://openalex.org/W4220843702","https://openalex.org/W4224030825","https://openalex.org/W4281638602","https://openalex.org/W4283693076","https://openalex.org/W4285021890","https://openalex.org/W4285593069","https://openalex.org/W4288051653","https://openalex.org/W4288685337","https://openalex.org/W4296620140","https://openalex.org/W4297198672","https://openalex.org/W4298146881","https://openalex.org/W4300687926","https://openalex.org/W4304165676","https://openalex.org/W4304687401","https://openalex.org/W4304892800","https://openalex.org/W4306965073","https://openalex.org/W4307407887","https://openalex.org/W4307871567","https://openalex.org/W4308783523","https://openalex.org/W4309408995","https://openalex.org/W4310027043","https://openalex.org/W4312212116","https://openalex.org/W4319321345","https://openalex.org/W4319870003","https://openalex.org/W4322617391","https://openalex.org/W4366774041","https://openalex.org/W4376132038","https://openalex.org/W4384925766","https://openalex.org/W4386461056","https://openalex.org/W4386491426","https://openalex.org/W4386567836","https://openalex.org/W4386753113","https://openalex.org/W4386913211","https://openalex.org/W4387661403","https://openalex.org/W4391718123"],"related_works":["https://openalex.org/W2072612684","https://openalex.org/W2359820976","https://openalex.org/W2355266152","https://openalex.org/W2425752205","https://openalex.org/W2072666767","https://openalex.org/W7095645591","https://openalex.org/W2394656753","https://openalex.org/W2377502718","https://openalex.org/W4405256446","https://openalex.org/W1996644622"],"abstract_inverted_index":{"Phosphatase":[0],"and":[1,19,26,35,42,56,66,80,97,106,113,121,126,130,142,178,205,220,228,263,279,293,306,313],"tensin":[2],"homologue":[3],"deleted":[4],"on":[5,154],"chromosome":[6],"ten":[7],"(PTEN)":[8],"was":[9,173],"initially":[10],"recognized":[11],"as":[12,108,110,201],"a":[13,90,147,166,266],"significant":[14],"regulator":[15],"of":[16,46,83,92,100,132,163,189,208],"cancer":[17,22],"suppression":[18],"could":[20],"impede":[21],"cell":[23],"survival,":[24],"proliferation,":[25],"energy":[27],"metabolism.":[28],"PTEN":[29,47,74,133,209,247,270,317],"is":[30,57,75,88,239],"highly":[31],"expressed":[32],"in":[33,39,52,77,115,134,139,186,210,248,271,276,288],"neurons":[34],"performs":[36],"crucial":[37],"functions":[38],"neurogenesis,":[40],"synaptogenesis,":[41],"neuronal":[43,54],"survival.":[44],"Disruption":[45],"activity":[48],"may":[49,215,259,301],"also":[50,300],"result":[51],"abnormal":[53],"function":[55],"associated":[58],"with":[59,169],"various":[60],"neurological":[61,143,280],"disorders,":[62],"including":[63],"stroke,":[64],"seizures,":[65],"autism.":[67],"Although":[68],"several":[69],"studies":[70,94],"have":[71,197],"shown":[72],"that":[73,95,160],"involved":[76],"the":[78,84,124,128,135,161,181,211,231,235,249,272],"development":[79,129,141,278],"degenerative":[81],"processes":[82],"nervous":[85,136,212,250,273,310],"system,":[86,137,213,274],"there":[87],"still":[89],"lack":[91],"in-depth":[93],"summarize":[96],"analyse":[98],"patterns":[99],"cooperation":[101,125],"between":[102],"authors,":[103],"institutions,":[104,177],"countries,":[105],"journals,":[107],"well":[109],"research":[111,195,244,261,291],"hotspots":[112,262],"trends":[114,131,245],"this":[116,155,172,187],"important":[117],"field.":[118],"To":[119],"identify":[120,151,242],"further":[122],"visualize":[123],"comprehend":[127],"especially":[138,275],"neural":[140,277],"diseases,":[144],"we":[145],"used":[146],"bibliometric":[148],"analysis":[149],"to":[150,241],"relevant":[152],"publications":[153,164],"topic.":[156],"We":[157],"first":[158],"found":[159],"number":[162],"displayed":[165],"growing":[167],"trend":[168],"time,":[170],"but":[171],"not":[174],"stable.":[175],"Universities,":[176],"authors":[179],"from":[180],"United":[182],"States":[183],"are":[184],"leading":[185],"area":[188],"research.":[190],"In":[191],"addition,":[192],"many":[193],"cutting-edge":[194],"results":[196],"been":[198],"discovered,":[199],"such":[200],"key":[202],"regulatory":[203],"molecules":[204],"cellular":[206],"mechanisms":[207],"which":[214],"provide":[216,302],"novel":[217],"intervention":[218],"targets":[219],"precise":[221,303],"therapeutic":[222],"strategies":[223,307],"for":[224,268,308],"related":[225],"pathological":[226],"injuries":[227,312],"diseases.":[229,281],"Finally,":[230],"literature":[232],"published":[233],"within":[234],"last":[236],"5":[237],"years":[238],"discussed":[240],"future":[243],"regarding":[246],"system.":[251],"Taken":[252],"together,":[253],"our":[254,298],"findings,":[255],"analysed":[256],"using":[257],"bibliometrics,":[258],"reflect":[260],"trends,":[264],"providing":[265],"reference":[267],"studying":[269],"These":[282],"findings":[283,299],"can":[284],"assist":[285],"new":[286],"researchers":[287],"developing":[289],"their":[290],"interests":[292],"gaining":[294],"basic":[295],"information.":[296],"Moreover,":[297],"clinical":[304],"guidelines":[305],"treating":[309],"system":[311],"diseases":[314],"caused":[315],"by":[316],"dysfunction.":[318]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2024-03-23T00:00:00"}