{"id":"https://openalex.org/W4393065072","doi":"https://doi.org/10.1055/a-2239-1284","title":"Endokrine Therapielandschaft bei Patient*innen mit HR+ HER2\u2212 fr\u00fchem Mammakarzinom in Deutschland vor Einf\u00fchrung der CDK4/6-Inhibitor-Behandlung \u2013 eine Real-World-Analyse","display_name":"Endokrine Therapielandschaft bei Patient*innen mit HR+ HER2\u2212 fr\u00fchem Mammakarzinom in Deutschland vor Einf\u00fchrung der CDK4/6-Inhibitor-Behandlung \u2013 eine Real-World-Analyse","publication_year":2024,"publication_date":"2024-03-01","ids":{"openalex":"https://openalex.org/W4393065072","doi":"https://doi.org/10.1055/a-2239-1284"},"language":"de","primary_location":{"id":"doi:10.1055/a-2239-1284","doi":"https://doi.org/10.1055/a-2239-1284","is_oa":true,"landing_page_url":"https://doi.org/10.1055/a-2239-1284","pdf_url":null,"source":{"id":"https://openalex.org/S4210169716","display_name":"Senologie - Zeitschrift f\u00fcr Mammadiagnostik und -therapie","issn_l":"1611-6453","issn":["1611-6453","1611-647X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310321135","host_organization_name":"Georg Thieme Verlag","host_organization_lineage":["https://openalex.org/P4310321135","https://openalex.org/P4310320000"],"host_organization_lineage_names":["Georg Thieme Verlag","Thieme Medical Publishers (Germany)"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Senologie - Zeitschrift f\u00fcr Mammadiagnostik und -therapie","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1055/a-2239-1284","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036608852","display_name":"Naiba Nabieva","orcid":"https://orcid.org/0000-0002-8065-0649","observed_orcids":["https://orcid.org/0000-0002-8065-0649"]},"institutions":[{"id":"https://openalex.org/I4210086790","display_name":"Novartis (Germany)","ror":"https://ror.org/0013shd50","country_code":"DE","type":"company","lineage":["https://openalex.org/I1283582996","https://openalex.org/I4210086790"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Naiba Nabieva","raw_affiliation_strings":["Novartis Pharma GmbH, N\u00fcrnberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novartis Pharma GmbH, N\u00fcrnberg, Germany","institution_ids":["https://openalex.org/I4210086790"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077406439","display_name":"Falk Altmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Falk Altmann","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Klaus Apel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Klaus Apel","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033658531","display_name":"Dirk-Toralf Baerens","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dirk-Toralf Baerens","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019885328","display_name":"Michaela Beha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michaela Beha","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084015382","display_name":"Antje Kristina Belau","orcid":"https://orcid.org/0000-0003-3549-1156","observed_orcids":["https://orcid.org/0000-0003-3549-1156"]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Antje Belau","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055679374","display_name":"Steffi Busch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Steffi Busch","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076643194","display_name":"Dagmar Guth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dagmar Guth","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109286608","display_name":"Georg Heinrich","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Georg Heinrich","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089143650","display_name":"Janine Kreiss-Sender","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Janine Kreiss-Sender","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050330159","display_name":"Susanne Markmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Susanne Markmann","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092492241","display_name":"Andreas Olbermann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Andreas Olbermann","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008264203","display_name":"G\u00fclten Oskay-\u00d6zcelik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"G\u00fclten Oskay-\u00d6zcelik","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050549494","display_name":"Beatrix Schuback","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Beatrix Schuback","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064198990","display_name":"Dieter Steinfeld\u2010Birg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dieter Steinfeld-Birg","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011101272","display_name":"Claudia Quiering","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086790","display_name":"Novartis (Germany)","ror":"https://ror.org/0013shd50","country_code":"DE","type":"company","lineage":["https://openalex.org/I1283582996","https://openalex.org/I4210086790"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Claudia Quiering","raw_affiliation_strings":["Novartis Pharma GmbH, N\u00fcrnberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novartis Pharma GmbH, N\u00fcrnberg, Germany","institution_ids":["https://openalex.org/I4210086790"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ferenc Kiss","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086790","display_name":"Novartis (Germany)","ror":"https://ror.org/0013shd50","country_code":"DE","type":"company","lineage":["https://openalex.org/I1283582996","https://openalex.org/I4210086790"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ferenc Kiss","raw_affiliation_strings":["Novartis Pharma GmbH, N\u00fcrnberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novartis Pharma GmbH, N\u00fcrnberg, Germany","institution_ids":["https://openalex.org/I4210086790"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004071807","display_name":"Julia Kreuzeder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086790","display_name":"Novartis (Germany)","ror":"https://ror.org/0013shd50","country_code":"DE","type":"company","lineage":["https://openalex.org/I1283582996","https://openalex.org/I4210086790"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Julia Kreuzeder","raw_affiliation_strings":["Novartis Pharma GmbH, N\u00fcrnberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novartis Pharma GmbH, N\u00fcrnberg, Germany","institution_ids":["https://openalex.org/I4210086790"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092492242","display_name":"Paolo Nuti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Paolo Nuti","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","HERACLIN Institut f\u00fcr Datenmanagement im Gesundheitswesen GmbH, Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]},{"raw_affiliation_string":"HERACLIN Institut f\u00fcr Datenmanagement im Gesundheitswesen GmbH, Neuenhagen bei Berlin, Germany","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004711304","display_name":"J\u00f6rg Schilling","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134833","display_name":"Berufsverband Niedergelassener Gyn\u00e4kologischer Onkologen","ror":"https://ror.org/02rn5zx43","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210134833"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J\u00f6rg Schilling","raw_affiliation_strings":["Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berufsverband Niedergelassener und ambulant t\u00e4tiger Gyn\u00e4kologischer Onkologen in Deutschland e. V., Neuenhagen bei Berlin, Germany","institution_ids":["https://openalex.org/I4210134833"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5036608852"],"corresponding_institution_ids":["https://openalex.org/I4210086790"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.04542195,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"21","issue":"01","first_page":"51","last_page":"60"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12829","display_name":"Advanced Breast Cancer Therapies","score":0.9580000042915344,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12829","display_name":"Advanced Breast Cancer Therapies","score":0.9580000042915344,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.040699999779462814,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10668","display_name":"Endometrial and Cervical Cancer Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hr-her2-early-breast-cancer","display_name":"HR+/HER2- early breast cancer","score":0.7829999923706055},{"id":"https://openalex.org/keywords/endocrine-therapy","display_name":"endocrine therapy","score":0.8539999723434448},{"id":"https://openalex.org/keywords/cdk4-6-inhibitors","display_name":"CDK4/6 inhibitors","score":0.9810000061988831},{"id":"https://openalex.org/keywords/tamoxifen","display_name":"tamoxifen","score":0.753000020980835},{"id":"https://openalex.org/keywords/aromatase-inhibitors","display_name":"aromatase inhibitors","score":0.9789999723434448},{"id":"https://openalex.org/keywords/ovariectomy","display_name":"ovariectomy","score":0.7360000014305115},{"id":"https://openalex.org/keywords/gnrh-analogs","display_name":"GnRH analogues","score":0.8730000257492065},{"id":"https://openalex.org/keywords/premenopausal-women","display_name":"premenopausal women","score":0.7200000286102295},{"id":"https://openalex.org/keywords/postmenopausal-women","display_name":"postmenopausal women","score":0.8040000200271606},{"id":"https://openalex.org/keywords/natalee-trial","display_name":"NATALEE trial","score":0.6140000224113464},{"id":"https://openalex.org/keywords/monarche-trial","display_name":"monarchE trial","score":0.800000011920929},{"id":"https://openalex.org/keywords/adjuvant-chemotherapy","display_name":"adjuvant chemotherapy","score":0.5699999928474426},{"id":"https://openalex.org/keywords/real-world-treatment-patterns","display_name":"real-world treatment patterns","score":0.6209999918937683},{"id":"https://openalex.org/keywords/germany","display_name":"Germany","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4951142370700836},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.43955257534980774}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1055/a-2239-1284","doi":"https://doi.org/10.1055/a-2239-1284","is_oa":true,"landing_page_url":"https://doi.org/10.1055/a-2239-1284","pdf_url":null,"source":{"id":"https://openalex.org/S4210169716","display_name":"Senologie - Zeitschrift f\u00fcr Mammadiagnostik und -therapie","issn_l":"1611-6453","issn":["1611-6453","1611-647X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310321135","host_organization_name":"Georg Thieme Verlag","host_organization_lineage":["https://openalex.org/P4310321135","https://openalex.org/P4310320000"],"host_organization_lineage_names":["Georg Thieme Verlag","Thieme Medical Publishers (Germany)"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Senologie - Zeitschrift f\u00fcr Mammadiagnostik und -therapie","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1055/a-2239-1284","doi":"https://doi.org/10.1055/a-2239-1284","is_oa":true,"landing_page_url":"https://doi.org/10.1055/a-2239-1284","pdf_url":null,"source":{"id":"https://openalex.org/S4210169716","display_name":"Senologie - Zeitschrift f\u00fcr Mammadiagnostik und -therapie","issn_l":"1611-6453","issn":["1611-6453","1611-647X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310321135","host_organization_name":"Georg Thieme Verlag","host_organization_lineage":["https://openalex.org/P4310321135","https://openalex.org/P4310320000"],"host_organization_lineage_names":["Georg Thieme Verlag","Thieme Medical Publishers (Germany)"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Senologie - Zeitschrift f\u00fcr Mammadiagnostik und -therapie","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1453600927","https://openalex.org/W2149615486","https://openalex.org/W2214665719","https://openalex.org/W2804105316","https://openalex.org/W2806866264","https://openalex.org/W2903514456","https://openalex.org/W2980534320","https://openalex.org/W3044605555","https://openalex.org/W3087501542","https://openalex.org/W3142429513","https://openalex.org/W3201975794","https://openalex.org/W4210476314","https://openalex.org/W4226348827","https://openalex.org/W4229009593","https://openalex.org/W4311675987"],"related_works":["https://openalex.org/W4384009333","https://openalex.org/W4384661788","https://openalex.org/W4297102258","https://openalex.org/W7107866807","https://openalex.org/W2789485627","https://openalex.org/W2869356851","https://openalex.org/W4380447729","https://openalex.org/W4322604018","https://openalex.org/W3042393276","https://openalex.org/W2828569947"],"abstract_inverted_index":{"Zusammenfassung":[0],"Einleitung":[1],"W\u00e4hrend":[2,131],"pr\u00e4menopausale":[3],"Patientinnen":[4,177,194,236],"mit":[5,11,16,38,53,91,185,219],"einem":[6,17,20,92,232,243],"HR+":[7,93],"HER2\u2212":[8,94],"fr\u00fchen":[9,51,95],"Mammakarzinom":[10,96],"Tamoxifen":[12,208],"+/\u2212":[13],"ovarielle":[14],"Suppression":[15],"GnRH-Analogon":[18],"oder":[19],"Aromataseinhibitor":[21],"(AI)":[22],"+":[23,203,209],"GnRH":[24,204,237],"behandelt":[25,75,227],"werden,":[26],"erhalten":[27],"postmenopausale":[28],"Frauen":[29,183],"vorwiegend":[30],"einen":[31],"AI":[32,202],"aufgrund":[33],"der":[34,45,60,110,112,136,147,151,157,161,166,176,181,192,234,258],"besseren":[35],"Wirksamkeit":[36],"verglichen":[37],"Tamoxifen.":[39],"Da":[40],"es":[41],"durch":[42,255],"den":[43,132,256],"Einzug":[44,257],"CDK4/6-Inhibitoren":[46,259],"in":[47,68,116,263],"die":[48,155,160,164,218,260],"Behandlung":[49],"des":[50,213],"Mammakarzinoms":[52],"h\u00f6herem":[54],"R\u00fcckfallrisiko":[55],"vermutlich":[56],"zu":[57,242,251],"einer":[58,82,98,186,220,225],"Verschiebung":[59],"endokrinen":[61],"Therapielandschaft":[62,262],"kommt,":[63],"ist":[64],"von":[65,89,124],"Interesse,":[66],"wie":[67,253],"Deutschland":[69,264],"potenzielle":[70],"CDK4/6-Inhibitor-Kandidat*innen":[71,107],"vor":[72],"deren":[73],"Markteinf\u00fchrung":[74],"wurden.":[76],"Patienten":[77],"und":[78,97,114,205],"Methoden":[79],"Im":[80,171],"Rahmen":[81],"retrospektiven,":[83],"multizentrischen":[84],"Analyse":[85],"wurden":[86,108,122,184],"anonymisierte":[87],"Daten":[88,123],"Patient*innen":[90,126,137,152,167],"im":[99,223],"Zeitraum":[100],"zwischen":[101],"10/2021\u201303/2022":[102],"begonnenen":[103],"Antihormontherapie":[104,198,239],"erhoben.":[105],"Potenzielle":[106],"anhand":[109],"Einschlusskriterien":[111,156],"NATALEE-":[113,158],"monarchE-Studien":[115],"entsprechende":[117],"Risikokollektive":[118],"unterteilt.":[119],"Ergebnisse":[120],"Insgesamt":[121],"238":[125],"aus":[127],"29":[128],"Zentren":[129],"analysiert.":[130],"monarchE-Kriterien":[133],"20,6":[134],"%":[135,146,150,175,180,191,201,207],"zugeordnet":[138],"werden":[139],"konnten,":[140],"enthielt":[141],"das":[142],"NATALEE-\u00e4hnliche":[143],"Kollektiv":[144],"46,2":[145],"Patient*innen.":[148],"53,8":[149],"erf\u00fcllten":[153],"weder":[154],"noch":[159],"monarchE-Studie.":[162],"\u00dcber":[163],"H\u00e4lfte":[165],"erhielt":[168],"keine":[169],"Chemotherapie.":[170],"Gesamtkollektiv":[172],"waren":[173],"28,6":[174],"pr\u00e4menopausal.":[178],"67,6":[179],"pr\u00e4menopausalen":[182,193,235],"neo-/adjuvanten":[187],"Chemotherapie":[188,226],"behandelt.":[189],"61,8":[190],"erhielten":[195],"als":[196],"adjuvante":[197],"Tamoxifen,":[199],"19,1":[200],"10,3":[206],"GnRH.":[210],"Schlussfolgerung":[211],"Trotz":[212],"hohen":[214],"Anteils":[215],"pr\u00e4menopausaler":[216],"Patientinnen,":[217],"aggressiven":[221],"Therapie":[222],"Sinne":[224],"wurden,":[228],"wurde":[229],"bei":[230],"nur":[231],"Drittel":[233],"zur":[238],"hinzugenommen.":[240],"Untersuchungen":[241],"sp\u00e4teren":[244],"Zeitpunkt":[245],"sowie":[246],"Registerstudien":[247],"sind":[248],"n\u00f6tig,":[249],"um":[250],"sehen,":[252],"sich":[254],"endokrine":[261],"ver\u00e4ndert.":[265]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2024-03-23T00:00:00"}