{"id":"https://openalex.org/W4392584479","doi":"https://doi.org/10.3389/fonc.2024.1304187","title":"Rim enhancement of pancreatic ductal adenocarcinoma: investigating the relationship with DCE-MRI-based radiomics and next-generation sequencing","display_name":"Rim enhancement of pancreatic ductal adenocarcinoma: investigating the relationship with DCE-MRI-based radiomics and next-generation sequencing","publication_year":2024,"publication_date":"2024-03-08","ids":{"openalex":"https://openalex.org/W4392584479","doi":"https://doi.org/10.3389/fonc.2024.1304187","pmid":"https://pubmed.ncbi.nlm.nih.gov/38525415","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10959187"},"language":"en","primary_location":{"id":"doi:10.3389/fonc.2024.1304187","doi":"https://doi.org/10.3389/fonc.2024.1304187","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fonc.2024.1304187","pdf_url":"https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1304187/pdf","source":{"id":"https://openalex.org/S2596394214","display_name":"Frontiers in Oncology","issn_l":"2234-943X","issn":["2234-943X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1304187/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029495151","display_name":"Moon Hyung Choi","orcid":"https://orcid.org/0000-0001-5962-4772","observed_orcids":["https://orcid.org/0000-0001-5962-4772"]},"institutions":[{"id":"https://openalex.org/I87111246","display_name":"Catholic University of Korea","ror":"https://ror.org/01fpnj063","country_code":"KR","type":"education","lineage":["https://openalex.org/I87111246"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Moon Hyung Choi","raw_affiliation_strings":["Department of Radiology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea","Department of Radiology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I87111246"]},{"raw_affiliation_string":"Department of Radiology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea","institution_ids":["https://openalex.org/I87111246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049255506","display_name":"Seung Bae Yoon","orcid":"https://orcid.org/0000-0002-6119-7236","observed_orcids":["https://orcid.org/0000-0002-6119-7236"]},"institutions":[{"id":"https://openalex.org/I87111246","display_name":"Catholic University of Korea","ror":"https://ror.org/01fpnj063","country_code":"KR","type":"education","lineage":["https://openalex.org/I87111246"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Seung Bae Yoon","raw_affiliation_strings":["Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea","Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I87111246"]},{"raw_affiliation_string":"Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea","institution_ids":["https://openalex.org/I87111246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101703157","display_name":"Young Joon Lee","orcid":"https://orcid.org/0000-0001-8309-0272","observed_orcids":["https://orcid.org/0000-0001-8309-0272"]},"institutions":[{"id":"https://openalex.org/I87111246","display_name":"Catholic University of Korea","ror":"https://ror.org/01fpnj063","country_code":"KR","type":"education","lineage":["https://openalex.org/I87111246"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Young Joon Lee","raw_affiliation_strings":["Department of Radiology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea","Department of Radiology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I87111246"]},{"raw_affiliation_string":"Department of Radiology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea","institution_ids":["https://openalex.org/I87111246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103043413","display_name":"Eun Sun Jung","orcid":"https://orcid.org/0000-0002-8451-939X","observed_orcids":["https://orcid.org/0000-0002-8451-939X","https://orcid.org/0000-0003-4274-254X"]},"institutions":[{"id":"https://openalex.org/I87111246","display_name":"Catholic University of Korea","ror":"https://ror.org/01fpnj063","country_code":"KR","type":"education","lineage":["https://openalex.org/I87111246"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Eun Sun Jung","raw_affiliation_strings":["Department of Hospital Pathology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea","Department of Hospital Pathology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hospital Pathology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I87111246"]},{"raw_affiliation_string":"Department of Hospital Pathology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea","institution_ids":["https://openalex.org/I87111246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049877509","display_name":"Seongyong Pak","orcid":"https://orcid.org/0000-0002-2978-2355","observed_orcids":["https://orcid.org/0000-0002-2978-2355"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Seongyong Pak","raw_affiliation_strings":["Research Collaboration, Siemens Healthineers Ltd., Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Collaboration, Siemens Healthineers Ltd., Seoul, Republic of Korea","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103168614","display_name":"Dongyeob Han","orcid":"https://orcid.org/0000-0002-1402-5036","observed_orcids":["https://orcid.org/0000-0002-1402-5036"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dongyeob Han","raw_affiliation_strings":["Research Collaboration, Siemens Healthineers Ltd., Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Collaboration, Siemens Healthineers Ltd., Seoul, Republic of Korea","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037057145","display_name":"Dominik Marcel Nickel","orcid":"https://orcid.org/0000-0002-0360-7233","observed_orcids":["https://orcid.org/0000-0002-0360-7233","https://orcid.org/0000-0001-6141-5857"]},"institutions":[{"id":"https://openalex.org/I4210153902","display_name":"Siemens Healthineers (Germany)","ror":"https://ror.org/0449c4c15","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210153902"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dominik Nickel","raw_affiliation_strings":["MR Applications Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MR Applications Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany","institution_ids":["https://openalex.org/I4210153902"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5049255506"],"corresponding_institution_ids":["https://openalex.org/I87111246"],"apc_list":{"value":3295,"currency":"USD","value_usd":3295},"apc_paid":{"value":3295,"currency":"USD","value_usd":3295},"fwci":0.7804,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.63180366,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"14","issue":null,"first_page":"1304187","last_page":"1304187"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.8574000000953674,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.8574000000953674,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.10100000351667404,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.036400001496076584,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pancreatic-ductal-adenocarcinoma","display_name":"pancreatic ductal adenocarcinoma","score":0.9980000257492065},{"id":"https://openalex.org/keywords/rim-enhancement","display_name":"rim enhancement","score":0.9940000176429749},{"id":"https://openalex.org/keywords/dynamic-contrast-enhanced-mri","display_name":"dynamic contrast-enhanced MRI","score":0.875},{"id":"https://openalex.org/keywords/radiomics","display_name":"radiomics","score":0.9819999933242798},{"id":"https://openalex.org/keywords/next-generation-sequencing","display_name":"next-generation sequencing","score":0.8429999947547913},{"id":"https://openalex.org/keywords/tp53-mutation","display_name":"TP53 mutation","score":0.7770000100135803},{"id":"https://openalex.org/keywords/cdkn2a-mutation","display_name":"CDKN2A mutation","score":0.9449999928474426},{"id":"https://openalex.org/keywords/smad4-mutation","display_name":"SMAD4 mutation","score":0.9940000176429749},{"id":"https://openalex.org/keywords/random-forest","display_name":"random forest","score":0.6150000095367432},{"id":"https://openalex.org/keywords/tumor-size","display_name":"tumor size","score":0.49000000953674316},{"id":"https://openalex.org/keywords/prognostic-imaging-biomarkers","display_name":"prognostic imaging biomarkers","score":0.6949999928474426},{"id":"https://openalex.org/keywords/ktrans","display_name":"Ktrans","score":0.3889999985694885},{"id":"https://openalex.org/keywords/kep","display_name":"Kep","score":0.8429999947547913},{"id":"https://openalex.org/keywords/ve","display_name":"Ve","score":0.49300000071525574}],"concepts":[{"id":"https://openalex.org/C2781187634","wikidata":"https://www.wikidata.org/wiki/Q20969980","display_name":"KRAS","level":4,"score":0.7365025877952576},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6586265563964844},{"id":"https://openalex.org/C2992026798","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic ductal adenocarcinoma","level":4,"score":0.6503828763961792},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.5894357562065125},{"id":"https://openalex.org/C2778559731","wikidata":"https://www.wikidata.org/wiki/Q23808793","display_name":"Radiomics","level":2,"score":0.5558682680130005},{"id":"https://openalex.org/C2780210213","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic cancer","level":3,"score":0.46357303857803345},{"id":"https://openalex.org/C12868164","wikidata":"https://www.wikidata.org/wiki/Q1424533","display_name":"Mann\u2013Whitney U test","level":2,"score":0.4182227849960327},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36666572093963623},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3551478385925293},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3529192805290222},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.19298601150512695},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fonc.2024.1304187","doi":"https://doi.org/10.3389/fonc.2024.1304187","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fonc.2024.1304187","pdf_url":"https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1304187/pdf","source":{"id":"https://openalex.org/S2596394214","display_name":"Frontiers in Oncology","issn_l":"2234-943X","issn":["2234-943X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Oncology","raw_type":"journal-article"},{"id":"pmid:38525415","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38525415","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in oncology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10959187","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10959187/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Oncol","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:a6601444c210400c93decda60bf7dcf5","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a6601444c210400c93decda60bf7dcf5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Oncology, Vol 14 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fonc.2024.1304187","doi":"https://doi.org/10.3389/fonc.2024.1304187","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fonc.2024.1304187","pdf_url":"https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1304187/pdf","source":{"id":"https://openalex.org/S2596394214","display_name":"Frontiers in Oncology","issn_l":"2234-943X","issn":["2234-943X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4392584479.pdf","grobid_xml":"https://content.openalex.org/works/W4392584479.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W2014647082","https://openalex.org/W2053371061","https://openalex.org/W2068638242","https://openalex.org/W2095494759","https://openalex.org/W2103812779","https://openalex.org/W2127890285","https://openalex.org/W2133125666","https://openalex.org/W2133872961","https://openalex.org/W2174661749","https://openalex.org/W2394646302","https://openalex.org/W2521201684","https://openalex.org/W2521800237","https://openalex.org/W2566723262","https://openalex.org/W2603473228","https://openalex.org/W2763355946","https://openalex.org/W2785043177","https://openalex.org/W2789159448","https://openalex.org/W2799271457","https://openalex.org/W2804265265","https://openalex.org/W2921968782","https://openalex.org/W2922510938","https://openalex.org/W2943052259","https://openalex.org/W2953404953","https://openalex.org/W2986293412","https://openalex.org/W2999027176","https://openalex.org/W3007013198","https://openalex.org/W3015389052","https://openalex.org/W3023545224","https://openalex.org/W3036064083","https://openalex.org/W3094406339","https://openalex.org/W3096322857","https://openalex.org/W3126704571","https://openalex.org/W3185094133","https://openalex.org/W3212190986","https://openalex.org/W4206664236","https://openalex.org/W4206841660","https://openalex.org/W4221106632","https://openalex.org/W4280519960","https://openalex.org/W4296435843","https://openalex.org/W4309450056","https://openalex.org/W4362639736"],"related_works":["https://openalex.org/W4401574818","https://openalex.org/W4394611947","https://openalex.org/W4415671843","https://openalex.org/W4409039147","https://openalex.org/W2799271457","https://openalex.org/W4404746666","https://openalex.org/W4296435843","https://openalex.org/W4317721881","https://openalex.org/W4321789421","https://openalex.org/W4312141111"],"abstract_inverted_index":{"Purpose":[0],"To":[1],"identify":[2,94],"the":[3,29,80,83,111,118,122,170,183,206,218,276,292,327],"clinical":[4,95],"and":[5,17,37,50,88,96,144,211,224,232,237,249,286,306],"genetic":[6,30,97,323],"variables":[7,98,107,175],"associated":[8,99,176,316],"with":[9,40,100,177,255,282,288,317],"rim":[10,64,101,109,178],"enhancement":[11,65,102,312],"of":[12,63,135,161,172,182,193,258,301,304,308,313],"pancreatic":[13,45],"ductal":[14],"adenocarcinoma":[15],"(PDAC)":[16],"to":[18,93,168,205],"develop":[19],"a":[20,68,133,159,256,299,333],"dynamic":[21],"contrast-enhanced":[22],"(DCE)":[23],"MRI-based":[24],"radiomics":[25,156,334],"model":[26,150,166,184,335],"for":[27,79,268],"predicting":[28,108,269,326],"status":[31,171,272,330],"from":[32,82,121,132,158,265,321],"next-generation":[33],"sequencing":[34],"(NGS)":[35],"Materials":[36],"methods":[38],"Patients":[39],"PDAC,":[41,67,332],"who":[42],"underwent":[43],"pretreatment":[44],"DCE-MRI":[46],"between":[47,244],"November":[48],"2019":[49],"July":[51],"2021,":[52],"were":[53,91,130,202,228],"eligible":[54],"in":[55,66,103,331],"this":[56],"prospective":[57],"study.":[58],"Two":[59],"radiologists":[60],"evaluated":[61],"presence":[62],"known":[69],"radiological":[70],"prognostic":[71],"indicator,":[72],"on":[73,117,137,337],"DCE":[74,139,338],"MRI.":[75],"NGS":[76,174],"was":[77,114,151,185,273],"conducted":[78],"tissue":[81],"lesion.":[84],"The":[85,180,260],"Mann-Whitney":[86],"U":[87],"Chi-square":[89],"tests":[90],"employed":[92],"PDAC.":[104],"For":[105,325],"continuous":[106],"enhancement,":[110],"cutoff":[112,257],"value":[113],"set":[115,278],"based":[116,336],"Youden\u2019s":[119],"index":[120],"receiver":[123],"operating":[124],"characteristic":[125],"(ROC)":[126],"curve.":[127],"Radiomics":[128],"features":[129,157],"extracted":[131],"volume-of-interest":[134],"PDAC":[136,314],"four":[138],"maps":[140,339],"(Ktrans,":[141],"Kep,":[142],"Ve,":[143],"iAUC).":[145],"A":[146,191],"random":[147],"forest":[148],"(RF)":[149],"constructed":[152],"using":[153,187],"10":[154],"selected":[155],"pool":[160],"392":[162],"original":[163],"features.":[164],"This":[165],"aimed":[167],"predict":[169],"significant":[173],"enhancement.":[179],"performance":[181],"validated":[186],"test":[188,212,277],"set.":[189],"Results":[190],"total":[192],"55":[194],"patients":[195],"(32":[196],"men;":[197],"median":[198],"age":[199],"71":[200],"years)":[201],"randomly":[203],"assigned":[204],"training":[207,219],"(n":[208,213,246,251],"=":[209,214,247,252],"41)":[210],"14)":[215],"sets.":[216],"In":[217,275],"set,":[220],"KRAS,":[221],"TP53,":[222],"CDKN2A,":[223],"SMAD4":[225],"mutation":[226],"rates":[227],"92.3%,":[229],"61.8%,":[230],"14.5%,":[231],"9.1%,":[233],"respectively.":[234],"Tumor":[235],"size":[236],"KRAS":[238,270,284,290,318,328],"variant":[239],"allele":[240],"frequency":[241],"(VAF)":[242],"differed":[243],"rim-enhancing":[245],"12)":[248],"nonrim-enhancing":[250],"29)":[253],"PDACs":[254],"17.22%.":[259],"RF":[261,293],"model\u2019s":[262,294],"average":[263],"AUC":[264,295],"10-fold":[266],"cross-validation":[267],"VAF":[271,285,319,329],"0.698.":[274],"comprising":[279],"6":[280],"tumors":[281],"low":[283],"8":[287],"high":[289],"VAF,":[291],"reached":[296],"1.000,":[297],"achieving":[298],"sensitivity":[300],"75.0%,":[302],"specificity":[303],"100%":[305],"accuracy":[307],"87.5%.":[309],"Conclusion":[310],"Rim":[311],"is":[315],"derived":[320],"NGS-based":[322],"information.":[324],"showed":[340],"promising":[341],"results.":[342]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2024-03-09T00:00:00"}