{"id":"https://openalex.org/W4392581869","doi":"https://doi.org/10.1016/j.bioadv.2024.213825","title":"Biomaterial Degradation Products affect Regenerating Glia Independently of Surface Properties","display_name":"Biomaterial Degradation Products affect Regenerating Glia Independently of Surface Properties","publication_year":2024,"publication_date":"2024-02-23","ids":{"openalex":"https://openalex.org/W4392581869","doi":"https://doi.org/10.1016/j.bioadv.2024.213825","pmid":"https://pubmed.ncbi.nlm.nih.gov/38479242","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10990769"},"language":"en","primary_location":{"id":"doi:10.1016/j.bioadv.2024.213825","doi":"https://doi.org/10.1016/j.bioadv.2024.213825","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bioadv.2024.213825","pdf_url":null,"source":{"id":"https://openalex.org/S4210239156","display_name":"Biomaterials Advances","issn_l":"2772-9508","issn":["2772-9508","2772-9516"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biomaterials Advances","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.bioadv.2024.213825","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059518362","display_name":"Kendell M. Pawelec","orcid":"https://orcid.org/0000-0003-2606-4136","observed_orcids":["https://orcid.org/0000-0003-2606-4136"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kendell M. Pawelec","raw_affiliation_strings":["Michigan State University, Department of Radiology, East Lansing, MI 48824, United States of America; Michigan State University, Institute for Quantitative Health Science and Engineering (IQ), East Lansing, MI 48824, United States of America. Electronic address: paweleck@msu.edu","Michigan State University, Department of Radiology, East Lansing, MI 48824, United States of America","Michigan State University, Institute for Quantitative Health Science and Engineering (IQ), East Lansing, MI 48824, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Michigan State University, Department of Radiology, East Lansing, MI 48824, United States of America; Michigan State University, Institute for Quantitative Health Science and Engineering (IQ), East Lansing, MI 48824, United States of America. Electronic address: paweleck@msu.edu","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Michigan State University, Department of Radiology, East Lansing, MI 48824, United States of America","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Michigan State University, Institute for Quantitative Health Science and Engineering (IQ), East Lansing, MI 48824, United States of America","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059521505","display_name":"Jeremy M.L. Hix","orcid":"https://orcid.org/0000-0002-9593-787X","observed_orcids":["https://orcid.org/0000-0002-9593-787X"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeremy M.L. Hix","raw_affiliation_strings":["Michigan State University, Department of Radiology, East Lansing, MI 48824, United States of America; Michigan State University, Institute for Quantitative Health Science and Engineering (IQ), East Lansing, MI 48824, United States of America","Michigan State University, Department of Radiology, East Lansing, MI 48824, United States of America","Michigan State University, Institute for Quantitative Health Science and Engineering (IQ), East Lansing, MI 48824, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Michigan State University, Department of Radiology, East Lansing, MI 48824, United States of America; Michigan State University, Institute for Quantitative Health Science and Engineering (IQ), East Lansing, MI 48824, United States of America","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Michigan State University, Department of Radiology, East Lansing, MI 48824, United States of America","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Michigan State University, Institute for Quantitative Health Science and Engineering (IQ), East Lansing, MI 48824, United States of America","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049750913","display_name":"Erik M. Shapiro","orcid":"https://orcid.org/0000-0002-0901-5781","observed_orcids":["https://orcid.org/0000-0002-0901-5781"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Erik M. Shapiro","raw_affiliation_strings":["Michigan State University, Department of Radiology, East Lansing, MI 48824, United States of America; Michigan State University, Institute for Quantitative Health Science and Engineering (IQ), East Lansing, MI 48824, United States of America; Michigan State University, Department of Physiology, East Lansing, MI 48824, United States of America; Michigan State University, Department of Chemical Engineering and Material Science, East Lansing, MI 48824, United States of America; Michigan State University, Department of Biomedical Engineering, East Lansing, MI 48824, United States of America. Electronic address: shapir86@msu.edu","Michigan State University, Department of Biomedical Engineering, East Lansing, MI 48824, United States of America","Michigan State University, Department of Chemical Engineering and Material Science, East Lansing, MI 48824, United States of America","Michigan State University, Department of Physiology, East Lansing, MI 48824, United States of America","Michigan State University, Department of Radiology, East Lansing, MI 48824, United States of America","Michigan State University, Institute for Quantitative Health Science and Engineering (IQ), East Lansing, MI 48824, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Michigan State University, Department of Radiology, East Lansing, MI 48824, United States of America; Michigan State University, Institute for Quantitative Health Science and Engineering (IQ), East Lansing, MI 48824, United States of America; Michigan State University, Department of Physiology, East Lansing, MI 48824, United States of America; Michigan State University, Department of Chemical Engineering and Material Science, East Lansing, MI 48824, United States of America; Michigan State University, Department of Biomedical Engineering, East Lansing, MI 48824, United States of America. Electronic address: shapir86@msu.edu","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Michigan State University, Department of Biomedical Engineering, East Lansing, MI 48824, United States of America","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Michigan State University, Department of Chemical Engineering and Material Science, East Lansing, MI 48824, United States of America","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Michigan State University, Department of Physiology, East Lansing, MI 48824, United States of America","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Michigan State University, Department of Radiology, East Lansing, MI 48824, United States of America","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Michigan State University, Institute for Quantitative Health Science and Engineering (IQ), East Lansing, MI 48824, United States of America","institution_ids":["https://openalex.org/I87216513"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5049750913","https://openalex.org/A5059518362"],"corresponding_institution_ids":["https://openalex.org/I87216513"],"apc_list":{"value":3910,"currency":"USD","value_usd":3910},"apc_paid":null,"fwci":1.3176,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.78271028,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"159","issue":null,"first_page":"213825","last_page":"213825"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.0066999997943639755,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schwann-cells","display_name":"Schwann cells","score":0.9169999957084656},{"id":"https://openalex.org/keywords/peripheral-nerve-injury","display_name":"peripheral nerve injury","score":0.9810000061988831},{"id":"https://openalex.org/keywords/nerve-regeneration","display_name":"nerve regeneration","score":0.6290000081062317},{"id":"https://openalex.org/keywords/polymer-degradation-products","display_name":"polymer degradation products","score":0.7099999785423279},{"id":"https://openalex.org/keywords/polycaprolactone","display_name":"polycaprolactone","score":0.8989999890327454},{"id":"https://openalex.org/keywords/plga","display_name":"PLGA","score":0.9210000038146973},{"id":"https://openalex.org/keywords/myelination","display_name":"myelination","score":0.7490000128746033},{"id":"https://openalex.org/keywords/schwann-cell-differentiation","display_name":"Schwann cell differentiation","score":0.753000020980835},{"id":"https://openalex.org/keywords/dorsal-root-ganglion-neurons","display_name":"dorsal root ganglion neurons","score":0.859000027179718},{"id":"https://openalex.org/keywords/beta-dystroglycan","display_name":"beta-dystroglycan","score":0.871999979019165},{"id":"https://openalex.org/keywords/integrin-alpha6","display_name":"CD49f","score":0.9869999885559082},{"id":"https://openalex.org/keywords/laminin-binding","display_name":"laminin binding","score":0.8399999737739563},{"id":"https://openalex.org/keywords/lactic-acid","display_name":"lactic acid","score":0.7699999809265137},{"id":"https://openalex.org/keywords/glycolytic-metabolism","display_name":"glycolytic metabolism","score":0.9810000061988831},{"id":"https://openalex.org/keywords/sox10","display_name":"SOX10","score":0.906000018119812}],"concepts":[{"id":"https://openalex.org/C2780165375","wikidata":"https://www.wikidata.org/wiki/Q2102907","display_name":"PLGA","level":3,"score":0.7438696622848511},{"id":"https://openalex.org/C2777004073","wikidata":"https://www.wikidata.org/wiki/Q465621","display_name":"Schwann cell","level":2,"score":0.6931740641593933},{"id":"https://openalex.org/C136940099","wikidata":"https://www.wikidata.org/wiki/Q6996839","display_name":"Nerve guidance conduit","level":3,"score":0.6240912675857544},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6063149571418762},{"id":"https://openalex.org/C2779814568","wikidata":"https://www.wikidata.org/wiki/Q58345","display_name":"Laminin","level":3,"score":0.570054829120636},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5100842118263245},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4135962724685669},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.36459195613861084},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.2759641408920288},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26126301288604736},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2543421685695648},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.1331552267074585}],"mesh":[{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005727","descriptor_name":"Ganglia, Spinal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012583","descriptor_name":"Schwann Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018920","descriptor_name":"Coculture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.bioadv.2024.213825","doi":"https://doi.org/10.1016/j.bioadv.2024.213825","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bioadv.2024.213825","pdf_url":null,"source":{"id":"https://openalex.org/S4210239156","display_name":"Biomaterials Advances","issn_l":"2772-9508","issn":["2772-9508","2772-9516"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biomaterials Advances","raw_type":"journal-article"},{"id":"doi:10.1101/2024.02.20.581223","doi":"https://doi.org/10.1101/2024.02.20.581223","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2024.02.20.581223","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:38479242","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38479242","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials advances","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10990769","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10990769","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10990769/pdf/nihms-1976848.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biomater Adv","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.bioadv.2024.213825","doi":"https://doi.org/10.1016/j.bioadv.2024.213825","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bioadv.2024.213825","pdf_url":null,"source":{"id":"https://openalex.org/S4210239156","display_name":"Biomaterials Advances","issn_l":"2772-9508","issn":["2772-9508","2772-9516"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biomaterials Advances","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000914969","display_name":"Radiopaque 3D printed tissue engineered scaffolds for nerve generation","funder_award_id":"R01EB029418","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"}],"funders":[{"id":"https://openalex.org/F4320310016","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332431","display_name":"College of Engineering, Michigan State University","ror":"https://ror.org/05hs6h993"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4392581869.pdf","grobid_xml":"https://content.openalex.org/works/W4392581869.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W1966468246","https://openalex.org/W1984054252","https://openalex.org/W1986583027","https://openalex.org/W2011281135","https://openalex.org/W2027242644","https://openalex.org/W2033708966","https://openalex.org/W2038650429","https://openalex.org/W2054918575","https://openalex.org/W2094381248","https://openalex.org/W2095978877","https://openalex.org/W2104439323","https://openalex.org/W2130618942","https://openalex.org/W2142254746","https://openalex.org/W2145659849","https://openalex.org/W2171957474","https://openalex.org/W2324566879","https://openalex.org/W2373823565","https://openalex.org/W2387119379","https://openalex.org/W2415781642","https://openalex.org/W2766993248","https://openalex.org/W2793825937","https://openalex.org/W2905374429","https://openalex.org/W2947075584","https://openalex.org/W2953359945","https://openalex.org/W3004759799","https://openalex.org/W3044394245","https://openalex.org/W3047451361","https://openalex.org/W3098861367","https://openalex.org/W3115667433","https://openalex.org/W3132133615","https://openalex.org/W4315783734","https://openalex.org/W4379194169","https://openalex.org/W4380758511"],"related_works":["https://openalex.org/W2033708966","https://openalex.org/W2019605886","https://openalex.org/W2111559825","https://openalex.org/W2954832021","https://openalex.org/W2320804448","https://openalex.org/W2969552620","https://openalex.org/W2160283328","https://openalex.org/W2072212515","https://openalex.org/W2317426999","https://openalex.org/W2015021320"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-03-09T00:00:00"}