{"id":"https://openalex.org/W4392556007","doi":"https://doi.org/10.3324/haematol.2022.282363","title":"Health-related quality of life in patients with hematologic malignancies treated with chimeric antigen receptor T-cell therapy: review and current progress","display_name":"Health-related quality of life in patients with hematologic malignancies treated with chimeric antigen receptor T-cell therapy: review and current progress","publication_year":2024,"publication_date":"2024-03-07","ids":{"openalex":"https://openalex.org/W4392556007","doi":"https://doi.org/10.3324/haematol.2022.282363","pmid":"https://pubmed.ncbi.nlm.nih.gov/38450528","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11290540"},"language":"en","primary_location":{"id":"doi:10.3324/haematol.2022.282363","doi":"https://doi.org/10.3324/haematol.2022.282363","is_oa":true,"landing_page_url":"https://doi.org/10.3324/haematol.2022.282363","pdf_url":null,"source":{"id":"https://openalex.org/S2752781272","display_name":"Haematologica","issn_l":"0390-6078","issn":["0390-6078","1592-8721"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317774","host_organization_name":"Ferrata Storti Foundation","host_organization_lineage":["https://openalex.org/P4310317774"],"host_organization_lineage_names":["Ferrata Storti Foundation"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Haematologica","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3324/haematol.2022.282363","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045707345","display_name":"Emmanuelle Tchernonog","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210093292","display_name":"Centre Hospitalier Universitaire de Montpellier","ror":"https://ror.org/00mthsf17","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210093292"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Emmanuelle Tchernonog","raw_affiliation_strings":["Hematology department, University hospital, Montpellier"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology department, University hospital, Montpellier","institution_ids":["https://openalex.org/I4210093292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032322234","display_name":"Aline Moignet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124872","display_name":"H\u00f4pital Pontchaillou","ror":"https://ror.org/02r25sw81","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210124872","https://openalex.org/I4210155724"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Aline Moignet","raw_affiliation_strings":["Hematology department, Pontchaillou University Hospital, Rennes"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology department, Pontchaillou University Hospital, Rennes","institution_ids":["https://openalex.org/I4210124872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012447228","display_name":"Am\u00e9lie Anota","orcid":"https://orcid.org/0000-0001-6896-1367","observed_orcids":["https://orcid.org/0000-0001-6896-1367"]},"institutions":[{"id":"https://openalex.org/I4210105738","display_name":"Centre L\u00e9on B\u00e9rard","ror":"https://ror.org/01cmnjq37","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210105738"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Am\u00e9lie Anota","raw_affiliation_strings":["Department of Clinical Research and Innovation and Department of Human and Social Sciences, Centre L\u00e9on B\u00e9rard, Lyon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Research and Innovation and Department of Human and Social Sciences, Centre L\u00e9on B\u00e9rard, Lyon","institution_ids":["https://openalex.org/I4210105738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052359098","display_name":"Sophie Bernard","orcid":"https://orcid.org/0000-0001-8039-1301","observed_orcids":["https://orcid.org/0000-0001-8039-1301"]},"institutions":[{"id":"https://openalex.org/I4210127258","display_name":"Centre Hospitalier de la C\u00f4te Basque","ror":"https://ror.org/03htsdy94","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210127258"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sophie Bernard","raw_affiliation_strings":["Hematology department, Centre Hospitalier de la C\u00f4te Basque, Bayonne"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology department, Centre Hospitalier de la C\u00f4te Basque, Bayonne","institution_ids":["https://openalex.org/I4210127258"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009104411","display_name":"Guy Bouguet","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guy Bouguet","raw_affiliation_strings":["Ensemble Leuc\u00e9mie Lymphomes Espoir (ELLyE), Paris"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ensemble Leuc\u00e9mie Lymphomes Espoir (ELLyE), Paris","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110988509","display_name":"Fanny Colin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124872","display_name":"H\u00f4pital Pontchaillou","ror":"https://ror.org/02r25sw81","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210124872","https://openalex.org/I4210155724"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fanny Colin","raw_affiliation_strings":["Hematology department, Pontchaillou University Hospital, Rennes"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology department, Pontchaillou University Hospital, Rennes","institution_ids":["https://openalex.org/I4210124872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046006290","display_name":"Catherine Rioufol","orcid":"https://orcid.org/0000-0002-9728-8092","observed_orcids":["https://orcid.org/0000-0002-9728-8092"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I4405260950","display_name":"Centre pour l'innovation en canc\u00e9rologie de Lyon","ror":"https://ror.org/04h6jac11","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264","https://openalex.org/I4405260950"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Catherine Rioufol","raw_affiliation_strings":["Clinical Oncology Pharmacy Department, University Lyon I, France - EA 3738 CICLY, University Hospital, Lyon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Oncology Pharmacy Department, University Lyon I, France - EA 3738 CICLY, University Hospital, Lyon","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I4405260950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013649293","display_name":"Lo\u00efc Ysebaert","orcid":"https://orcid.org/0000-0003-4102-7261","observed_orcids":["https://orcid.org/0000-0003-4102-7261","https://orcid.org/0000-0001-8478-5623"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I134560555","display_name":"Universit\u00e9 Toulouse III - Paul Sabatier","ror":"https://ror.org/02v6kpv12","country_code":"FR","type":"education","lineage":["https://openalex.org/I134560555","https://openalex.org/I4405258862"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I3019448017","display_name":"Centre Hospitalier Universitaire de Toulouse","ror":"https://ror.org/017h5q109","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017"]},{"id":"https://openalex.org/I4210087620","display_name":"Centre de Recherches en Canc\u00e9rologie de Toulouse","ror":"https://ror.org/003412r28","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210087620","https://openalex.org/I4405258862"]},{"id":"https://openalex.org/I4210098740","display_name":"Institut universitaire du cancer de Toulouse Oncopole","ror":"https://ror.org/014hxhm89","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210098740","https://openalex.org/I4210128666"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Lo\u00efc Ysebaert","raw_affiliation_strings":["Toulouse Cancer Research Center (CRCT), INSERM, CNRS, Toulouse III Paul Sabatier University, Toulouse, France; Clinical Hematology, IUCT Oncopole, Toulouse University Hospital, Toulouse. Ysebaert.Loic@iuct-oncopole.fr","Clinical Hematology, IUCT Oncopole, Toulouse University Hospital, Toulouse","Toulouse Cancer Research Center (CRCT), INSERM, CNRS, Toulouse III Paul Sabatier University, Toulouse, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Toulouse Cancer Research Center (CRCT), INSERM, CNRS, Toulouse III Paul Sabatier University, Toulouse, France; Clinical Hematology, IUCT Oncopole, Toulouse University Hospital, Toulouse. Ysebaert.Loic@iuct-oncopole.fr","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I134560555","https://openalex.org/I154526488","https://openalex.org/I3019448017","https://openalex.org/I4210087620","https://openalex.org/I4210098740"]},{"raw_affiliation_string":"Clinical Hematology, IUCT Oncopole, Toulouse University Hospital, Toulouse","institution_ids":["https://openalex.org/I3019448017","https://openalex.org/I4210098740"]},{"raw_affiliation_string":"Toulouse Cancer Research Center (CRCT), INSERM, CNRS, Toulouse III Paul Sabatier University, Toulouse, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I134560555","https://openalex.org/I154526488","https://openalex.org/I4210087620"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079890028","display_name":"Emmanuel Gyan","orcid":"https://orcid.org/0000-0002-7651-9189","observed_orcids":["https://orcid.org/0000-0002-7651-9189"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210095477","display_name":"Centre Hospitalier Universitaire de Tours","ror":"https://ror.org/00jpq0w62","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210095477"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Emmanuel Gyan","raw_affiliation_strings":["Hematology and cell therapy department, University Hospital, Tours, France; Clinical investigation center, INSERM U1415, University Hospital, Tours","Clinical investigation center, INSERM U1415, University Hospital, Tours","Hematology and cell therapy department, University Hospital, Tours, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology and cell therapy department, University Hospital, Tours, France; Clinical investigation center, INSERM U1415, University Hospital, Tours","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210095477"]},{"raw_affiliation_string":"Clinical investigation center, INSERM U1415, University Hospital, Tours","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210095477"]},{"raw_affiliation_string":"Hematology and cell therapy department, University Hospital, Tours, France","institution_ids":["https://openalex.org/I4210095477"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":13,"corresponding_author_ids":["https://openalex.org/A5013649293"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I134560555","https://openalex.org/I154526488","https://openalex.org/I3019448017","https://openalex.org/I4210087620","https://openalex.org/I4210098740"],"apc_list":{"value":2000,"currency":"EUR","value_usd":2157},"apc_paid":{"value":2000,"currency":"EUR","value_usd":2157},"fwci":0.4796,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.47597701,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"109","issue":"8","first_page":"2401","last_page":"2419"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.9560999870300293,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.9560999870300293,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.029100000858306885,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/car-t-cell-therapy","display_name":"CAR T-cell therapy","score":0.9480000138282776},{"id":"https://openalex.org/keywords/health-related-quality-of-life","display_name":"health-related quality of life","score":0.9959999918937683},{"id":"https://openalex.org/keywords/patient-reported-outcomes","display_name":"patient-reported outcomes","score":0.8610000014305115},{"id":"https://openalex.org/keywords/relapsed-refractory-hematologic-malignancies","display_name":"relapsed/refractory hematologic malignancies","score":0.8629999756813049},{"id":"https://openalex.org/keywords/lymphoma","display_name":"lymphoma","score":0.7310000061988831},{"id":"https://openalex.org/keywords/leukemia","display_name":"leukemia","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cd19","display_name":"CD19","score":0.8949999809265137},{"id":"https://openalex.org/keywords/b-cell-maturation-antigen","display_name":"BCMA","score":0.8519999980926514},{"id":"https://openalex.org/keywords/cytokine-release-syndrome","display_name":"cytokine release syndrome","score":0.9819999933242798},{"id":"https://openalex.org/keywords/immune-effector-cell-associated-neurotoxicity-syndrome","display_name":"immune effector cell-associated neurotoxicity syndrome","score":0.9610000252723694},{"id":"https://openalex.org/keywords/adverse-events","display_name":"adverse events","score":0.5130000114440918}],"concepts":[{"id":"https://openalex.org/C3875195","wikidata":"https://www.wikidata.org/wiki/Q5099363","display_name":"Chimeric antigen receptor","level":4,"score":0.9132826328277588},{"id":"https://openalex.org/C2780850621","wikidata":"https://www.wikidata.org/wiki/Q3961647","display_name":"Cytokine release syndrome","level":5,"score":0.7845392227172852},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7706406712532043},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.592515766620636},{"id":"https://openalex.org/C10882517","wikidata":"https://www.wikidata.org/wiki/Q15268054","display_name":"Cell therapy","level":3,"score":0.5663371086120605},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.5293876528739929},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.4473867416381836},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.39268064498901367},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.39249008893966675},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35475021600723267},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.34945014119148254},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.31362277269363403},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2503652274608612},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000076962","descriptor_name":"Receptors, Chimeric Antigen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016219","descriptor_name":"Immunotherapy, Adoptive","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D016219","descriptor_name":"Immunotherapy, Adoptive","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019337","descriptor_name":"Hematologic Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.3324/haematol.2022.282363","doi":"https://doi.org/10.3324/haematol.2022.282363","is_oa":true,"landing_page_url":"https://doi.org/10.3324/haematol.2022.282363","pdf_url":null,"source":{"id":"https://openalex.org/S2752781272","display_name":"Haematologica","issn_l":"0390-6078","issn":["0390-6078","1592-8721"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317774","host_organization_name":"Ferrata Storti Foundation","host_organization_lineage":["https://openalex.org/P4310317774"],"host_organization_lineage_names":["Ferrata Storti Foundation"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Haematologica","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11290540","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11290540","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11290540/pdf/1092401.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Haematologica","raw_type":"Text"},{"id":"pmid:38450528","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38450528","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Haematologica","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:inserm-04773951v1","doi":null,"is_oa":true,"landing_page_url":"https://inserm.hal.science/inserm-04773951","pdf_url":"https://inserm.hal.science/inserm-04773951v1/file/1092401.pdf","source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Haematologica, 2024, 109 (8), pp.2401-2419. ⟨10.3324/haematol.2022.282363⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:ccca91ceeb7e41c187522d6681e708ea","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/ccca91ceeb7e41c187522d6681e708ea","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Haematologica, Vol 999, Iss 1 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3324/haematol.2022.282363","doi":"https://doi.org/10.3324/haematol.2022.282363","is_oa":true,"landing_page_url":"https://doi.org/10.3324/haematol.2022.282363","pdf_url":null,"source":{"id":"https://openalex.org/S2752781272","display_name":"Haematologica","issn_l":"0390-6078","issn":["0390-6078","1592-8721"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317774","host_organization_name":"Ferrata Storti Foundation","host_organization_lineage":["https://openalex.org/P4310317774"],"host_organization_lineage_names":["Ferrata Storti Foundation"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Haematologica","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320308573","display_name":"Gilead Sciences","ror":"https://ror.org/056546b03"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4392556007.pdf","grobid_xml":"https://content.openalex.org/works/W4392556007.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W2018304470","https://openalex.org/W2105258029","https://openalex.org/W2109364152","https://openalex.org/W2153836018","https://openalex.org/W2167571044","https://openalex.org/W2563130015","https://openalex.org/W2793808927","https://openalex.org/W2795705603","https://openalex.org/W2902598369","https://openalex.org/W2903062212","https://openalex.org/W2979548369","https://openalex.org/W2979910156","https://openalex.org/W2979947027","https://openalex.org/W3003917950","https://openalex.org/W3007507981","https://openalex.org/W3014583893","https://openalex.org/W3082855561","https://openalex.org/W3089727781","https://openalex.org/W3119335258","https://openalex.org/W3133898608","https://openalex.org/W3136045254","https://openalex.org/W3150462000","https://openalex.org/W3157319952","https://openalex.org/W3169193862","https://openalex.org/W3179765930","https://openalex.org/W3197920680","https://openalex.org/W3204391124","https://openalex.org/W3206710308","https://openalex.org/W3213961466","https://openalex.org/W4229081570","https://openalex.org/W4229377559","https://openalex.org/W4280495736","https://openalex.org/W4280527122","https://openalex.org/W4281726274","https://openalex.org/W4285492548","https://openalex.org/W4296714474","https://openalex.org/W4297016769","https://openalex.org/W4309411030","https://openalex.org/W4310296350","https://openalex.org/W4310593501","https://openalex.org/W4311280981","https://openalex.org/W4313887581","https://openalex.org/W4317738157","https://openalex.org/W4319059258","https://openalex.org/W4361279352","https://openalex.org/W4362451642","https://openalex.org/W4366607034","https://openalex.org/W4386271644"],"related_works":["https://openalex.org/W4405749862","https://openalex.org/W3197920680","https://openalex.org/W2979910156","https://openalex.org/W4298147214","https://openalex.org/W7220917229","https://openalex.org/W4310096770","https://openalex.org/W7164302178","https://openalex.org/W4311280981","https://openalex.org/W4414490680","https://openalex.org/W2949484690"],"abstract_inverted_index":{"Chimeric":[0],"antigen":[1],"receptor":[2],"(CAR)":[3],"T-cell":[4,21,41,65,93,166,207,227],"therapy":[5,42,66,94,141,167,208],"has":[6],"transformed":[7],"the":[8,36,69,88,91,101,162,194,216,222,236],"care":[9,174],"of":[10,71,82,90,106,126,156,164,170,238],"patients":[11,107,118,210],"with":[12,35,45,119,211],"relapsed/refractory":[13],"B-cell-derived":[14],"hematologic":[15,123],"malignancies.":[16],"To":[17],"date,":[18],"six":[19],"CAR":[20,40,64,92,165,206,226],"therapies,":[22],"targeting":[23],"either":[24],"CD19":[25],"or":[26,121,213],"B-cell":[27],"maturation":[28],"antigen,":[29],"have":[30,132],"received":[31],"regulatory":[32],"approval.":[33],"Along":[34],"promising":[37],"survival":[38],"benefit,":[39],"is":[43,145,151],"associated":[44],"potentially":[46],"life-threatening":[47],"adverse":[48,73,98],"events,":[49,74],"including":[50],"cytokine":[51],"release":[52],"syndrome":[53],"and":[54,96,103,111,135,175,177,201,229,233,240],"immune":[55],"effector":[56],"cell-associated":[57],"neurotoxicity":[58],"syndrome.":[59],"While":[60],"clinical":[61,199],"trials":[62,76,200],"evaluating":[63],"consistently":[67],"report":[68],"incidence":[70],"these":[72],"most":[75,223],"do":[77],"not":[78,146],"collect":[79],"health-related":[80],"quality":[81,169],"life":[83],"(HRQoL)":[84],"data.":[85],"As":[86],"such,":[87],"impact":[89,163],"process":[95],"related":[97],"events":[99],"on":[100,168],"physical":[102],"psychological":[104],"well-being":[105],"remains":[108],"uncertain.":[109],"HRQoL":[110,195,231,239],"other":[112,241],"patient-reported":[113],"outcome":[114],"(PRO)":[115],"assessments":[116],"in":[117,198,202,209],"relapsed":[120],"refractory":[122],"malignancies":[124],"are":[125],"utmost":[127],"importance,":[128],"as":[129],"individuals":[130],"may":[131,244],"unmet":[133],"needs":[134],"a":[136,143,185],"high":[137],"demand":[138],"for":[139],"tolerable":[140],"if":[142],"cure":[144],"obtained.":[147],"In":[148,215],"addition,":[149],"it":[150],"important":[152],"to":[153,159,189,192],"standardize":[154],"methods":[155],"data":[157],"collection":[158],"better":[160],"assess":[161],"life,":[171],"optimize":[172],"patients'":[173],"costs,":[176],"enable":[178],"comparisons":[179],"between":[180],"different":[181],"studies.":[182],"We":[183],"conducted":[184],"literature":[186],"search":[187],"up":[188],"June":[190],"2023":[191],"identify":[193],"tools":[196,232,243],"used":[197,225],"real-world":[203],"studies":[204],"investigating":[205],"lymphomas":[212],"leukemias.":[214],"present":[217],"comprehensive":[218],"review,":[219],"we":[220],"summarize":[221],"commonly":[224],"specific":[228],"non-specific":[230],"discuss":[234],"how":[235],"use":[237],"PRO":[242],"be":[245],"optimized.":[246]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2024-03-08T00:00:00"}