{"id":"https://openalex.org/W4392467661","doi":"https://doi.org/10.1002/adfm.202400585","title":"Research Progress on Injectable Microspheres as New Strategies for the Treatment of Osteoarthritis Through Promotion of Cartilage Repair","display_name":"Research Progress on Injectable Microspheres as New Strategies for the Treatment of Osteoarthritis Through Promotion of Cartilage Repair","publication_year":2024,"publication_date":"2024-03-04","ids":{"openalex":"https://openalex.org/W4392467661","doi":"https://doi.org/10.1002/adfm.202400585"},"language":"en","primary_location":{"id":"doi:10.1002/adfm.202400585","doi":"https://doi.org/10.1002/adfm.202400585","is_oa":true,"landing_page_url":"https://doi.org/10.1002/adfm.202400585","pdf_url":null,"source":{"id":"https://openalex.org/S135204980","display_name":"Advanced Functional Materials","issn_l":"1616-301X","issn":["1616-301X","1616-3028"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-3","ki-jl-3","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Functional Materials","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1002/adfm.202400585","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005376103","display_name":"Jianjing Lin","orcid":"https://orcid.org/0000-0002-1586-1415","observed_orcids":["https://orcid.org/0000-0002-1586-1415"]},"institutions":[{"id":"https://openalex.org/I4210128628","display_name":"Peking University Shenzhen Hospital","ror":"https://ror.org/03kkjyb15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128628"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianjing Lin","raw_affiliation_strings":["Department of Sports Medicine and Rehabilitation Peking University Shenzhen Hospital Shenzhen Guangdong 518036 P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sports Medicine and Rehabilitation Peking University Shenzhen Hospital Shenzhen Guangdong 518036 P. R. China","institution_ids":["https://openalex.org/I4210128628"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035539008","display_name":"Shicheng Jia","orcid":"https://orcid.org/0009-0008-8489-0827","observed_orcids":["https://orcid.org/0009-0008-8489-0827"]},"institutions":[{"id":"https://openalex.org/I4210120522","display_name":"Shantou University Medical College","ror":"https://ror.org/02gxych78","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210120522"]},{"id":"https://openalex.org/I4210128628","display_name":"Peking University Shenzhen Hospital","ror":"https://ror.org/03kkjyb15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128628"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shicheng Jia","raw_affiliation_strings":["Department of Sports Medicine and Rehabilitation Peking University Shenzhen Hospital Shenzhen Guangdong 518036 P. R. China","Shantou University Medical College Shantou Guangdong 515041 P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sports Medicine and Rehabilitation Peking University Shenzhen Hospital Shenzhen Guangdong 518036 P. R. China","institution_ids":["https://openalex.org/I4210128628"]},{"raw_affiliation_string":"Shantou University Medical College Shantou Guangdong 515041 P. R. China","institution_ids":["https://openalex.org/I4210120522"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Fuyang Cao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210133678","display_name":"Second Hospital of Shanxi Medical University","ror":"https://ror.org/03tn5kh37","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210133678"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fuyang Cao","raw_affiliation_strings":["Department of Orthopedics Second Hospital of Shanxi Medical University Taiyuan Shanxi 030001 P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics Second Hospital of Shanxi Medical University Taiyuan Shanxi 030001 P. R. China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210133678"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102952122","display_name":"Jingtao Huang","orcid":"https://orcid.org/0000-0003-4104-2402","observed_orcids":["https://orcid.org/0000-0003-4104-2402"]},"institutions":[{"id":"https://openalex.org/I4210120522","display_name":"Shantou University Medical College","ror":"https://ror.org/02gxych78","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210120522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingtao Huang","raw_affiliation_strings":["Shantou University Medical College Shantou Guangdong 515041 P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shantou University Medical College Shantou Guangdong 515041 P. R. China","institution_ids":["https://openalex.org/I4210120522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006752283","display_name":"Jiayou Chen","orcid":"https://orcid.org/0000-0001-8648-7072","observed_orcids":["https://orcid.org/0000-0001-8648-7072"]},"institutions":[{"id":"https://openalex.org/I4210120522","display_name":"Shantou University Medical College","ror":"https://ror.org/02gxych78","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210120522"]},{"id":"https://openalex.org/I4210128628","display_name":"Peking University Shenzhen Hospital","ror":"https://ror.org/03kkjyb15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128628"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiayou Chen","raw_affiliation_strings":["Department of Sports Medicine and Rehabilitation Peking University Shenzhen Hospital Shenzhen Guangdong 518036 P. R. China","Shantou University Medical College Shantou Guangdong 515041 P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sports Medicine and Rehabilitation Peking University Shenzhen Hospital Shenzhen Guangdong 518036 P. R. China","institution_ids":["https://openalex.org/I4210128628"]},{"raw_affiliation_string":"Shantou University Medical College Shantou Guangdong 515041 P. R. China","institution_ids":["https://openalex.org/I4210120522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100347411","display_name":"Juan Wang","orcid":"https://orcid.org/0000-0002-3726-4021","observed_orcids":["https://orcid.org/0000-0002-3726-4021"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Juan Wang","raw_affiliation_strings":["Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200025 P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200025 P. R. China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026416686","display_name":"Peng Liu","orcid":"https://orcid.org/0000-0002-8002-9705","observed_orcids":["https://orcid.org/0000-0002-8002-9705"]},"institutions":[{"id":"https://openalex.org/I4210128628","display_name":"Peking University Shenzhen Hospital","ror":"https://ror.org/03kkjyb15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128628"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peng Liu","raw_affiliation_strings":["National & Local Joint Engineering Research Center of Orthopaedic Biomaterials Peking University Shenzhen Hospital Shenzhen Guangdong 518036 P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National & Local Joint Engineering Research Center of Orthopaedic Biomaterials Peking University Shenzhen Hospital Shenzhen Guangdong 518036 P. R. China","institution_ids":["https://openalex.org/I4210128628"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084741386","display_name":"Hui Zeng","orcid":"https://orcid.org/0000-0001-6966-0769","observed_orcids":["https://orcid.org/0000-0001-6966-0769"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I4210164332","display_name":"Shenzhen Second People's Hospital","ror":"https://ror.org/05c74bq69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210164332"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hui Zeng","raw_affiliation_strings":["Shenzhen Second People's Hospital (First Affiliated Hospital of Shenzhen University) Shenzhen Guangdong 518035 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Second People's Hospital (First Affiliated Hospital of Shenzhen University) Shenzhen Guangdong 518035 China","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101623055","display_name":"Xintao Zhang","orcid":"https://orcid.org/0000-0001-9926-3756","observed_orcids":["https://orcid.org/0000-0001-9926-3756"]},"institutions":[{"id":"https://openalex.org/I4210128628","display_name":"Peking University Shenzhen Hospital","ror":"https://ror.org/03kkjyb15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128628"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xintao Zhang","raw_affiliation_strings":["Department of Sports Medicine and Rehabilitation Peking University Shenzhen Hospital Shenzhen Guangdong 518036 P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sports Medicine and Rehabilitation Peking University Shenzhen Hospital Shenzhen Guangdong 518036 P. R. China","institution_ids":["https://openalex.org/I4210128628"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085065266","display_name":"Wenguo Cui","orcid":"https://orcid.org/0000-0002-6938-9582","observed_orcids":["https://orcid.org/0000-0002-6938-9582"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wenguo Cui","raw_affiliation_strings":["Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200025 P. R. China"],"raw_orcid":"https://orcid.org/0000-0002-6938-9582","affiliations":[{"raw_affiliation_string":"Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200025 P. R. China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5084741386","https://openalex.org/A5085065266","https://openalex.org/A5101623055"],"corresponding_institution_ids":["https://openalex.org/I180726961","https://openalex.org/I183067930","https://openalex.org/I2801556517","https://openalex.org/I4210128628","https://openalex.org/I4210164332"],"apc_list":{"value":5510,"currency":"USD","value_usd":5510},"apc_paid":{"value":5510,"currency":"USD","value_usd":5510},"fwci":11.1757,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.99109232,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"34","issue":"33","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.009999999776482582,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/osteoarthritis","display_name":"osteoarthritis","score":0.9919999837875366},{"id":"https://openalex.org/keywords/injectable-microspheres","display_name":"injectable microspheres","score":0.9879999756813049},{"id":"https://openalex.org/keywords/cartilage-repair","display_name":"cartilage repair","score":0.9950000047683716},{"id":"https://openalex.org/keywords/cartilage-regeneration","display_name":"cartilage regeneration","score":0.9829999804496765},{"id":"https://openalex.org/keywords/drug-delivery-systems","display_name":"drug delivery systems","score":0.8489999771118164},{"id":"https://openalex.org/keywords/surface-modification","display_name":"surface modification","score":0.7799999713897705},{"id":"https://openalex.org/keywords/cell-proliferation-and-differentiation","display_name":"cell proliferation and differentiation","score":0.7160000205039978}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.828710675239563},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.7858800888061523},{"id":"https://openalex.org/C189942447","wikidata":"https://www.wikidata.org/wiki/Q61186","display_name":"Microsphere","level":2,"score":0.7791285514831543},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.666861891746521},{"id":"https://openalex.org/C98147612","wikidata":"https://www.wikidata.org/wiki/Q215599","display_name":"Promotion (chess)","level":3,"score":0.657148540019989},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.48035749793052673},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.44620200991630554},{"id":"https://openalex.org/C55587333","wikidata":"https://www.wikidata.org/wiki/Q1133029","display_name":"Engineering ethics","level":1,"score":0.36091458797454834},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26232999563217163},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.13501563668251038},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.101311594247818},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.09771108627319336},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.08264657855033875},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.07530796527862549},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.06852126121520996},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/adfm.202400585","doi":"https://doi.org/10.1002/adfm.202400585","is_oa":true,"landing_page_url":"https://doi.org/10.1002/adfm.202400585","pdf_url":null,"source":{"id":"https://openalex.org/S135204980","display_name":"Advanced Functional Materials","issn_l":"1616-301X","issn":["1616-301X","1616-3028"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-3","ki-jl-3","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Functional Materials","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1002/adfm.202400585","doi":"https://doi.org/10.1002/adfm.202400585","is_oa":true,"landing_page_url":"https://doi.org/10.1002/adfm.202400585","pdf_url":null,"source":{"id":"https://openalex.org/S135204980","display_name":"Advanced Functional Materials","issn_l":"1616-301X","issn":["1616-301X","1616-3028"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-3","ki-jl-3","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Functional Materials","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6425182474","display_name":null,"funder_award_id":"52273133","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7834305109","display_name":null,"funder_award_id":"2022XD055","funder_id":"https://openalex.org/F4320328346","funder_display_name":"Shanghai Municipal Health and Family Planning Commission"},{"id":"https://openalex.org/G8780093230","display_name":null,"funder_award_id":"82272568","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320328346","display_name":"Shanghai Municipal Health and Family Planning Commission","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":293,"referenced_works":["https://openalex.org/W69797112","https://openalex.org/W1819906559","https://openalex.org/W1909969017","https://openalex.org/W1968960597","https://openalex.org/W1971500643","https://openalex.org/W1971794940","https://openalex.org/W1971971965","https://openalex.org/W1972039893","https://openalex.org/W1972502240","https://openalex.org/W1972979183","https://openalex.org/W1973863009","https://openalex.org/W1975807705","https://openalex.org/W1976327023","https://openalex.org/W1976884216","https://openalex.org/W1977784832","https://openalex.org/W1978714754","https://openalex.org/W1980183393","https://openalex.org/W1980981669","https://openalex.org/W1983222105","https://openalex.org/W1985004392","https://openalex.org/W1985914247","https://openalex.org/W1993523958","https://openalex.org/W1996773341","https://openalex.org/W1999126001","https://openalex.org/W1999133016","https://openalex.org/W1999881827","https://openalex.org/W2001841831","https://openalex.org/W2006433730","https://openalex.org/W2007140197","https://openalex.org/W2007489591","https://openalex.org/W2010404343","https://openalex.org/W2012142451","https://openalex.org/W2013973141","https://openalex.org/W2014357380","https://openalex.org/W2017506406","https://openalex.org/W2017869529","https://openalex.org/W2020338027","https://openalex.org/W2022234371","https://openalex.org/W2022253175","https://openalex.org/W2026076082","https://openalex.org/W2026285963","https://openalex.org/W2026932813","https://openalex.org/W2027831505","https://openalex.org/W2029114553","https://openalex.org/W2031998936","https://openalex.org/W2038627947","https://openalex.org/W2038961315","https://openalex.org/W2039107753","https://openalex.org/W2039653102","https://openalex.org/W2042617428","https://openalex.org/W2043423139","https://openalex.org/W2043575440","https://openalex.org/W2044242789","https://openalex.org/W2044586568","https://openalex.org/W2047534346","https://openalex.org/W2047866615","https://openalex.org/W2048605020","https://openalex.org/W2051504085","https://openalex.org/W2053483127","https://openalex.org/W2055379256","https://openalex.org/W2056466478","https://openalex.org/W2057025655","https://openalex.org/W2058912292","https://openalex.org/W2061939813","https://openalex.org/W2063246959","https://openalex.org/W2063852117","https://openalex.org/W2067081122","https://openalex.org/W2068289128","https://openalex.org/W2070353556","https://openalex.org/W2072529576","https://openalex.org/W2075125957","https://openalex.org/W2075978331","https://openalex.org/W2076078537","https://openalex.org/W2076281703","https://openalex.org/W2076923477","https://openalex.org/W2080035178","https://openalex.org/W2082039872","https://openalex.org/W2083198311","https://openalex.org/W2085294880","https://openalex.org/W2090199647","https://openalex.org/W2092218516","https://openalex.org/W2095135703","https://openalex.org/W2095558856","https://openalex.org/W2096923422","https://openalex.org/W2104086077","https://openalex.org/W2111708595","https://openalex.org/W2114424736","https://openalex.org/W2114804734","https://openalex.org/W2116394678","https://openalex.org/W2122838755","https://openalex.org/W2131945662","https://openalex.org/W2140239410","https://openalex.org/W2141331032","https://openalex.org/W2142666593","https://openalex.org/W2151776485","https://openalex.org/W2153327670","https://openalex.org/W2158587075","https://openalex.org/W2160186897","https://openalex.org/W2172005299","https://openalex.org/W2181778634","https://openalex.org/W2194343859","https://openalex.org/W2195884409","https://openalex.org/W2204827672","https://openalex.org/W2212499052","https://openalex.org/W2240820333","https://openalex.org/W2288101340","https://openalex.org/W2308051128","https://openalex.org/W2312768877","https://openalex.org/W2318012368","https://openalex.org/W2323817265","https://openalex.org/W2326554500","https://openalex.org/W2326646895","https://openalex.org/W2396064369","https://openalex.org/W2416498869","https://openalex.org/W2419230544","https://openalex.org/W2461202700","https://openalex.org/W2461909646","https://openalex.org/W2467516967","https://openalex.org/W2520649746","https://openalex.org/W2526266802","https://openalex.org/W2534177175","https://openalex.org/W2548676616","https://openalex.org/W2553909066","https://openalex.org/W2561319457","https://openalex.org/W2591860844","https://openalex.org/W2592828555","https://openalex.org/W2593093093","https://openalex.org/W2605081110","https://openalex.org/W2606554067","https://openalex.org/W2611922931","https://openalex.org/W2619038371","https://openalex.org/W2620435339","https://openalex.org/W2621120485","https://openalex.org/W2730179537","https://openalex.org/W2739744022","https://openalex.org/W2765240768","https://openalex.org/W2771396902","https://openalex.org/W2775076315","https://openalex.org/W2781511541","https://openalex.org/W2786076295","https://openalex.org/W2793321255","https://openalex.org/W2797700396","https://openalex.org/W2799392860","https://openalex.org/W2800085734","https://openalex.org/W2800248573","https://openalex.org/W2801710223","https://openalex.org/W2802685346","https://openalex.org/W2804309624","https://openalex.org/W2807009021","https://openalex.org/W2828917163","https://openalex.org/W2884179233","https://openalex.org/W2884254952","https://openalex.org/W2889101189","https://openalex.org/W2889372700","https://openalex.org/W2890535036","https://openalex.org/W2890940368","https://openalex.org/W2891220007","https://openalex.org/W2899970640","https://openalex.org/W2900302887","https://openalex.org/W2907035923","https://openalex.org/W2912839439","https://openalex.org/W2939968077","https://openalex.org/W2946864560","https://openalex.org/W2949771071","https://openalex.org/W2951694119","https://openalex.org/W2956030553","https://openalex.org/W2965823829","https://openalex.org/W2966888496","https://openalex.org/W2967114568","https://openalex.org/W2970471465","https://openalex.org/W2971181141","https://openalex.org/W2971472479","https://openalex.org/W2975517112","https://openalex.org/W2976002556","https://openalex.org/W2982420772","https://openalex.org/W2985729762","https://openalex.org/W2987909994","https://openalex.org/W2990670938","https://openalex.org/W2991041619","https://openalex.org/W2991236826","https://openalex.org/W2992405751","https://openalex.org/W2994243494","https://openalex.org/W2994618781","https://openalex.org/W2995832713","https://openalex.org/W3001803099","https://openalex.org/W3007507664","https://openalex.org/W3013544570","https://openalex.org/W3016555584","https://openalex.org/W3023701441","https://openalex.org/W3024165904","https://openalex.org/W3025891185","https://openalex.org/W3034592955","https://openalex.org/W3037139532","https://openalex.org/W3042716055","https://openalex.org/W3046090877","https://openalex.org/W3087701954","https://openalex.org/W3091324538","https://openalex.org/W3092452908","https://openalex.org/W3092869268","https://openalex.org/W3095012295","https://openalex.org/W3106692906","https://openalex.org/W3107325235","https://openalex.org/W3108587538","https://openalex.org/W3111781561","https://openalex.org/W3112048380","https://openalex.org/W3126319243","https://openalex.org/W3127107918","https://openalex.org/W3127698120","https://openalex.org/W3137078406","https://openalex.org/W3141007726","https://openalex.org/W3154112332","https://openalex.org/W3155209389","https://openalex.org/W3161229325","https://openalex.org/W3162119155","https://openalex.org/W3173612696","https://openalex.org/W3175662601","https://openalex.org/W3175766113","https://openalex.org/W3179150874","https://openalex.org/W3184263143","https://openalex.org/W3184717675","https://openalex.org/W3187604200","https://openalex.org/W3195236121","https://openalex.org/W3198244376","https://openalex.org/W3201325635","https://openalex.org/W3203562265","https://openalex.org/W3209594283","https://openalex.org/W3213544292","https://openalex.org/W3214060438","https://openalex.org/W4200065279","https://openalex.org/W4200076949","https://openalex.org/W4200441452","https://openalex.org/W4205693429","https://openalex.org/W4206587236","https://openalex.org/W4210254819","https://openalex.org/W4210376801","https://openalex.org/W4210481130","https://openalex.org/W4211069396","https://openalex.org/W4211157371","https://openalex.org/W4212826067","https://openalex.org/W4214644148","https://openalex.org/W4214831396","https://openalex.org/W4220960625","https://openalex.org/W4221068621","https://openalex.org/W4223438838","https://openalex.org/W4224268772","https://openalex.org/W4224524205","https://openalex.org/W4225003989","https://openalex.org/W4229006680","https://openalex.org/W4244274695","https://openalex.org/W4250412796","https://openalex.org/W4281845704","https://openalex.org/W4284895583","https://openalex.org/W4284959083","https://openalex.org/W4286252870","https://openalex.org/W4290720782","https://openalex.org/W4291162568","https://openalex.org/W4291884882","https://openalex.org/W4294221244","https://openalex.org/W4294405960","https://openalex.org/W4294670536","https://openalex.org/W4296037368","https://openalex.org/W4296347970","https://openalex.org/W4296401130","https://openalex.org/W4296658315","https://openalex.org/W4296904320","https://openalex.org/W4301398328","https://openalex.org/W4302024446","https://openalex.org/W4309875273","https://openalex.org/W4313593881","https://openalex.org/W4315642182","https://openalex.org/W4317358902","https://openalex.org/W4317360753","https://openalex.org/W4321496474","https://openalex.org/W4322723763","https://openalex.org/W4322769891","https://openalex.org/W4324030674","https://openalex.org/W4360993734","https://openalex.org/W4361191095","https://openalex.org/W4368347894","https://openalex.org/W4378174639","https://openalex.org/W4378894825","https://openalex.org/W4378902978","https://openalex.org/W4382068925","https://openalex.org/W4382728072","https://openalex.org/W4384120255","https://openalex.org/W4385212390","https://openalex.org/W4385781825","https://openalex.org/W4386594485","https://openalex.org/W4387232965","https://openalex.org/W4387591792","https://openalex.org/W4389373273","https://openalex.org/W4390080189","https://openalex.org/W4391165155"],"related_works":["https://openalex.org/W7204899154","https://openalex.org/W4400354434","https://openalex.org/W7134954587","https://openalex.org/W4413995503","https://openalex.org/W3210443669","https://openalex.org/W4416787145","https://openalex.org/W4400948345","https://openalex.org/W7166556513","https://openalex.org/W4309875273","https://openalex.org/W7133197703"],"abstract_inverted_index":{"Abstract":[0],"Osteoarthritis":[1],"(OA)":[2],"is":[3,130,178],"a":[4,9,145],"degenerative":[5],"disease":[6],"caused":[7],"by":[8],"variety":[10],"of":[11,26,35,57,83,117,141,147,149,170,175,195,198],"factors":[12],"with":[13],"joint":[14],"pain":[15],"as":[16],"the":[17,33,55,65,81,138,161,173,193],"main":[18],"symptom,":[19],"including":[20],"fibrosis,":[21],"chapping,":[22],"ulcers,":[23],"and":[24,37,71,74,94,105,114,143,166,180,185],"loss":[25],"cartilage.":[27],"Traditional":[28],"treatment":[29,124,197],"can":[30,61,89,136],"only":[31],"delay":[32],"progression":[34],"OA,":[36],"classical":[38],"delivery":[39,78],"system":[40,79],"have":[41,49,98],"many":[42],"side":[43],"effects.":[44],"In":[45,107],"recent":[46],"years,":[47],"microspheres":[48,119,142,171],"shown":[50],"great":[51],"application":[52],"prospects":[53],"in":[54,69,72,102,122,153,172],"field":[56,174,194],"OA":[58,123,154,176],"treatment.":[59,155],"Microspheres":[60],"support":[62],"cells,":[63],"reproduce":[64],"natural":[66],"tissue":[67],"microenvironment":[68],"vitro":[70],"vivo,":[73],"are":[75,125],"an":[76],"efficient":[77],"for":[80],"release":[82],"drugs":[84],"or":[85],"biological":[86,139],"agents,":[87],"which":[88],"promote":[90],"cell":[91],"proliferation,":[92],"migration,":[93],"differentiation.":[95],"Thus,":[96],"they":[97],"been":[99],"widely":[100],"used":[101,121],"cartilage":[103],"repair":[104],"regeneration.":[106],"this":[108],"review,":[109],"preparation":[110],"processes,":[111],"basic":[112],"materials,":[113],"functional":[115],"characteristics":[116],"various":[118],"commonly":[120],"systematically":[126,179],"reviewed.":[127],"Then":[128],"it":[129],"introduced":[131],"surface":[132],"modification":[133],"strategies":[134],"that":[135],"improve":[137],"properties":[140],"discussed":[144],"series":[146],"applications":[148],"microsphere":[150,196],"functionalized":[151],"scaffolds":[152],"Finally,":[156],"based":[157],"on":[158],"bibliometrics":[159],"research,":[160],"research":[162,168],"development,":[163],"future":[164],"potential,":[165],"possible":[167],"hotspots":[169],"therapy":[177],"dynamically":[181],"evaluated.":[182],"The":[183],"comprehensive":[184],"systematic":[186],"review":[187],"will":[188],"bring":[189],"new":[190],"understanding":[191],"to":[192],"OA.":[199]},"counts_by_year":[{"year":2026,"cited_by_count":18},{"year":2025,"cited_by_count":21},{"year":2024,"cited_by_count":5}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2024-03-06T00:00:00"}