{"id":"https://openalex.org/W4391996997","doi":"https://doi.org/10.1002/jvc2.385","title":"A practical guide to over\u2010the\u2010counter treatments for hyperpigmentation","display_name":"A practical guide to over\u2010the\u2010counter treatments for hyperpigmentation","publication_year":2024,"publication_date":"2024-02-21","ids":{"openalex":"https://openalex.org/W4391996997","doi":"https://doi.org/10.1002/jvc2.385"},"language":"en","primary_location":{"id":"doi:10.1002/jvc2.385","doi":"https://doi.org/10.1002/jvc2.385","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jvc2.385","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jvc2.385","source":{"id":"https://openalex.org/S4210221814","display_name":"JEADV Clinical Practice","issn_l":"2768-6566","issn":["2768-6566"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JEADV Clinical Practice","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jvc2.385","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023170060","display_name":"Mustufa Jafry","orcid":"https://orcid.org/0009-0002-5521-018X","observed_orcids":["https://orcid.org/0009-0002-5521-018X"]},"institutions":[{"id":"https://openalex.org/I154057602","display_name":"Henry Ford Health","ror":"https://ror.org/02kwnkm68","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I154057602"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mustufa Jafry","raw_affiliation_strings":["Department of Dermatology Henry Ford Health Detroit Michigan USA"],"raw_orcid":"https://orcid.org/0009-0002-5521-018X","affiliations":[{"raw_affiliation_string":"Department of Dermatology Henry Ford Health Detroit Michigan USA","institution_ids":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041056232","display_name":"Linna L. Guan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I154057602","display_name":"Henry Ford Health","ror":"https://ror.org/02kwnkm68","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I154057602"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Linna L. Guan","raw_affiliation_strings":["Department of Dermatology Henry Ford Health Detroit Michigan USA","Department of Dermatology MD Anderson Cancer Center Houston Texas USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology Henry Ford Health Detroit Michigan USA","institution_ids":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]},{"raw_affiliation_string":"Department of Dermatology MD Anderson Cancer Center Houston Texas USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071271780","display_name":"Tasneem F. Mohammad","orcid":"https://orcid.org/0000-0002-1374-1815","observed_orcids":["https://orcid.org/0000-0002-1374-1815"]},"institutions":[{"id":"https://openalex.org/I154057602","display_name":"Henry Ford Health","ror":"https://ror.org/02kwnkm68","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I154057602"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Tasneem F. Mohammad","raw_affiliation_strings":["Department of Dermatology Henry Ford Health Detroit Michigan USA"],"raw_orcid":"https://orcid.org/0000-0002-1374-1815","affiliations":[{"raw_affiliation_string":"Department of Dermatology Henry Ford Health Detroit Michigan USA","institution_ids":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5071271780"],"corresponding_institution_ids":["https://openalex.org/I154057602","https://openalex.org/I2803043754"],"apc_list":{"value":2700,"currency":"USD","value_usd":2700},"apc_paid":{"value":2700,"currency":"USD","value_usd":2700},"fwci":1.8483,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.83038098,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"3","issue":"2","first_page":"433","last_page":"447"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11172","display_name":"Dermatologic Treatments and Research","score":0.6660000085830688,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11172","display_name":"Dermatologic Treatments and Research","score":0.6660000085830688,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11144","display_name":"melanin and skin pigmentation","score":0.3296000063419342,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10392","display_name":"Cutaneous Melanoma Detection and Management","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperpigmentation","display_name":"hyperpigmentation","score":0.9459999799728394},{"id":"https://openalex.org/keywords/post-inflammatory-hyperpigmentation","display_name":"post-inflammatory hyperpigmentation","score":0.9860000014305115},{"id":"https://openalex.org/keywords/melasma","display_name":"melasma","score":0.9990000128746033},{"id":"https://openalex.org/keywords/fitzpatrick-skin-type","display_name":"Fitzpatrick skin type","score":0.8799999952316284},{"id":"https://openalex.org/keywords/product-regulation","display_name":"product regulation","score":0.628000020980835},{"id":"https://openalex.org/keywords/treatment-efficacy-and-safety","display_name":"treatment efficacy and safety","score":0.6809999942779541},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.6320000290870667}],"concepts":[{"id":"https://openalex.org/C2776728111","wikidata":"https://www.wikidata.org/wiki/Q1641068","display_name":"Hyperpigmentation","level":2,"score":0.9007127285003662},{"id":"https://openalex.org/C2776677263","wikidata":"https://www.wikidata.org/wiki/Q305190","display_name":"Melasma","level":2,"score":0.7879893779754639},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7639339566230774},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.6868215203285217},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.6668479442596436},{"id":"https://openalex.org/C2777988657","wikidata":"https://www.wikidata.org/wiki/Q66320","display_name":"Over-the-counter","level":3,"score":0.5854775309562683},{"id":"https://openalex.org/C2909381827","wikidata":"https://www.wikidata.org/wiki/Q1641068","display_name":"Skin hyperpigmentation","level":3,"score":0.46345067024230957},{"id":"https://openalex.org/C150966472","wikidata":"https://www.wikidata.org/wiki/Q3410145","display_name":"Psychosocial","level":2,"score":0.4429621696472168},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.15221241116523743},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.09045597910881042}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1002/jvc2.385","doi":"https://doi.org/10.1002/jvc2.385","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jvc2.385","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jvc2.385","source":{"id":"https://openalex.org/S4210221814","display_name":"JEADV Clinical Practice","issn_l":"2768-6566","issn":["2768-6566"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JEADV Clinical Practice","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:c9ccde3dc48843c3bcc99b9bc54486ff","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c9ccde3dc48843c3bcc99b9bc54486ff","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"JEADV Clinical Practice, Vol 3, Iss 2, Pp 433-447 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1002/jvc2.385","doi":"https://doi.org/10.1002/jvc2.385","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jvc2.385","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jvc2.385","source":{"id":"https://openalex.org/S4210221814","display_name":"JEADV Clinical Practice","issn_l":"2768-6566","issn":["2768-6566"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JEADV Clinical Practice","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4391996997.pdf","grobid_xml":"https://content.openalex.org/works/W4391996997.grobid-xml"},"referenced_works_count":103,"referenced_works":["https://openalex.org/W36704158","https://openalex.org/W62746491","https://openalex.org/W384991803","https://openalex.org/W1519379554","https://openalex.org/W1729437282","https://openalex.org/W1838788707","https://openalex.org/W1905363600","https://openalex.org/W1944436417","https://openalex.org/W1949050414","https://openalex.org/W1953070490","https://openalex.org/W1971528399","https://openalex.org/W1972021260","https://openalex.org/W1992035582","https://openalex.org/W1998076973","https://openalex.org/W2002085398","https://openalex.org/W2003636646","https://openalex.org/W2011724551","https://openalex.org/W2015049089","https://openalex.org/W2017524766","https://openalex.org/W2031879731","https://openalex.org/W2067888481","https://openalex.org/W2076121443","https://openalex.org/W2087382008","https://openalex.org/W2090020569","https://openalex.org/W2095289520","https://openalex.org/W2101456910","https://openalex.org/W2102756952","https://openalex.org/W2103744556","https://openalex.org/W2118364917","https://openalex.org/W2121028352","https://openalex.org/W2124472391","https://openalex.org/W2132069508","https://openalex.org/W2132258567","https://openalex.org/W2134940134","https://openalex.org/W2136609383","https://openalex.org/W2139034283","https://openalex.org/W2140582311","https://openalex.org/W2144524662","https://openalex.org/W2152058987","https://openalex.org/W2164721645","https://openalex.org/W2168604244","https://openalex.org/W2184454410","https://openalex.org/W2290498379","https://openalex.org/W2325451653","https://openalex.org/W2332926516","https://openalex.org/W2493235774","https://openalex.org/W2529086782","https://openalex.org/W2559770021","https://openalex.org/W2594424919","https://openalex.org/W2595190693","https://openalex.org/W2597910756","https://openalex.org/W2702621875","https://openalex.org/W2786693416","https://openalex.org/W2791717670","https://openalex.org/W2808846090","https://openalex.org/W2811117926","https://openalex.org/W2888496641","https://openalex.org/W2889224962","https://openalex.org/W2891979137","https://openalex.org/W2899478934","https://openalex.org/W2903960063","https://openalex.org/W2916881945","https://openalex.org/W2929511339","https://openalex.org/W2973780047","https://openalex.org/W2980495754","https://openalex.org/W2982232673","https://openalex.org/W2982701779","https://openalex.org/W2983102494","https://openalex.org/W2988749586","https://openalex.org/W2991431892","https://openalex.org/W2997384848","https://openalex.org/W3006673889","https://openalex.org/W3008559776","https://openalex.org/W3009541511","https://openalex.org/W3017873412","https://openalex.org/W3019640062","https://openalex.org/W3021972214","https://openalex.org/W3022841045","https://openalex.org/W3045615572","https://openalex.org/W3045824735","https://openalex.org/W3047252761","https://openalex.org/W3082695913","https://openalex.org/W3088070633","https://openalex.org/W3088738647","https://openalex.org/W3104965558","https://openalex.org/W3113339021","https://openalex.org/W3128772242","https://openalex.org/W3131019845","https://openalex.org/W3134096581","https://openalex.org/W3136079049","https://openalex.org/W3160894884","https://openalex.org/W3197830448","https://openalex.org/W3214446229","https://openalex.org/W3217690561","https://openalex.org/W4205400451","https://openalex.org/W4206335595","https://openalex.org/W4210985581","https://openalex.org/W4213193526","https://openalex.org/W4234833792","https://openalex.org/W4243272783","https://openalex.org/W4285017725","https://openalex.org/W4297994894","https://openalex.org/W4303514526"],"related_works":["https://openalex.org/W7169880514","https://openalex.org/W3168443826","https://openalex.org/W2912489207","https://openalex.org/W2982870562","https://openalex.org/W4411022093","https://openalex.org/W4408497888","https://openalex.org/W3200997589","https://openalex.org/W7117566357","https://openalex.org/W3094837170","https://openalex.org/W157351941"],"abstract_inverted_index":{"Abstract":[0],"Hyperpigmentation":[1],"of":[2,23,51,75,110,131,171,188,206,226,232],"the":[3,10,64,107,168,186,192,202,212,222,230],"skin,":[4],"defined":[5],"as":[6,120,122],"increased":[7],"melanin":[8],"in":[9,70],"epidermis,":[11],"is":[12,149],"a":[13,49,91],"common":[14,67],"condition":[15],"associated":[16],"with":[17,154],"psychosocial":[18],"impairment":[19],"and":[20,33,77,85,97,117,129,142,167,195,204,224],"decreased":[21],"quality":[22],"life.":[24],"Prescription":[25],"options":[26,52],"are":[27,53,177],"often":[28],"not":[29],"covered":[30],"by":[31,191],"insurance":[32,165],"can":[34,56],"be":[35,57],"cost":[36,170],"prohibitive.":[37],"As":[38],"such,":[39],"many":[40],"turn":[41],"to":[42,62,83,102,163],"over\u2010the\u2010counter":[43,174],"(OTC)":[44,175],"products":[45,72,133,228],"for":[46,66,73,80,180,221,229],"treatment.":[47],"However,":[48,185],"plethora":[50],"available,":[54],"which":[55],"confusing.":[58],"This":[59],"review":[60,216],"aims":[61],"evaluate":[63],"evidence":[65],"ingredients":[68],"found":[69],"OTC":[71,125,132,227],"management":[74],"hyperpigmentation":[76,114,148,183],"provide":[78],"guidance":[79,220],"optimal":[81],"use":[82],"clinicians":[84],"consumers.":[86],"To":[87],"perform":[88],"this":[89,215],"review,":[90],"comprehensive":[92],"literature":[93],"search":[94],"utilizing":[95],"PubMed":[96],"Google":[98],"Scholar":[99],"was":[100],"conducted":[101],"identify":[103],"relevant":[104,124],"studies":[105],"on":[106,123,137],"clinico\u2010epidemiological":[108],"aspects":[109],"hyperpigmentation,":[111,119],"including":[112],"postinflammatory":[113,182],"(PIH),":[115],"melasma":[116],"maturational":[118],"well":[121],"treatments.":[126],"The":[127],"efficacy":[128,205],"safety":[130,203],"were":[134],"assessed":[135],"based":[136],"available":[138],"evidence,":[139],"clinical":[140],"trials":[141],"expert":[143],"recommendations.":[144],"Our":[145],"results":[146],"showed":[147],"more":[150],"prevalent":[151],"among":[152],"individuals":[153],"darker":[155],"skin":[156,159],"types":[157],"(Fitzpatrick":[158],"phototypes":[160],"III\u2013VI).":[161],"Due":[162],"limited":[164],"coverage":[166],"high":[169],"prescription":[172],"options,":[173],"treatments":[176],"widely":[178],"used":[179],"managing":[181],"(PIH).":[184],"lack":[187],"strict":[189],"regulation":[190],"US":[193],"Food":[194],"Drug":[196],"Administration":[197],"(FDA)":[198],"raises":[199],"concerns":[200],"about":[201],"these":[207],"products.":[208],"By":[209],"critically":[210],"evaluating":[211],"existing":[213],"literature,":[214],"offers":[217],"practical,":[218],"evidence\u2010based":[219],"selection":[223],"utilization":[225],"treatment":[231],"hyperpigmentation.":[233]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-02-22T00:00:00"}
