{"id":"https://openalex.org/W4391990602","doi":"https://doi.org/10.1055/s-0044-1779921","title":"Pituitary Adenomas with Subarachnoid Invasion: Surgical Nuances and Outcomes","display_name":"Pituitary Adenomas with Subarachnoid Invasion: Surgical Nuances and Outcomes","publication_year":2024,"publication_date":"2024-02-01","ids":{"openalex":"https://openalex.org/W4391990602","doi":"https://doi.org/10.1055/s-0044-1779921"},"language":"en","primary_location":{"id":"doi:10.1055/s-0044-1779921","doi":"https://doi.org/10.1055/s-0044-1779921","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0044-1779921","pdf_url":null,"source":{"id":"https://openalex.org/S4210197100","display_name":"Journal of Neurological Surgery Part B Skull Base","issn_l":"2193-6331","issn":["2193-6331","2193-634X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurological Surgery Part B: Skull Base","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039676534","display_name":"Jonathan Balquiedra Lamano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan B. Lamano","raw_affiliation_strings":["Stanford University, Stanford, California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford University, Stanford, California, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016767559","display_name":"Christine Kyuyoung Lee","orcid":"https://orcid.org/0000-0003-1422-4606","observed_orcids":["https://orcid.org/0000-0003-1422-4606"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christine K. Lee","raw_affiliation_strings":["Stanford University, Stanford, California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford University, Stanford, California, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080096952","display_name":"Karam Paul Asmaro","orcid":"https://orcid.org/0000-0002-2084-4863","observed_orcids":["https://orcid.org/0000-0002-2084-4863"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karam P. Asmaro","raw_affiliation_strings":["Stanford University, Stanford, California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford University, Stanford, California, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039496825","display_name":"Adrian John Rodrigues","orcid":"https://orcid.org/0000-0002-9371-1623","observed_orcids":["https://orcid.org/0000-0002-9371-1623"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adrian J. Rodrigues","raw_affiliation_strings":["Stanford University, Stanford, California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford University, Stanford, California, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017877801","display_name":"Juan Carlos Fernandez-Miranda","orcid":"https://orcid.org/0000-0002-0669-810X","observed_orcids":["https://orcid.org/0000-0002-0669-810X","https://orcid.org/0000-0003-2423-6213"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Juan Carlos Fernandez-Miranda","raw_affiliation_strings":["Stanford University, Stanford, California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford University, Stanford, California, United States","institution_ids":["https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I97018004"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.02433809,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"85","issue":"S 01","first_page":"S1","last_page":"S398"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11669","display_name":"Head and Neck Surgical Oncology","score":0.013299999758601189,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pituitary-adenoma","display_name":"pituitary adenoma","score":0.9559999704360962},{"id":"https://openalex.org/keywords/suprasellar-tumor","display_name":"suprasellar tumor","score":0.6010000109672546},{"id":"https://openalex.org/keywords/endoscopic-endonasal-approach","display_name":"endoscopic endonasal approach","score":0.9279999732971191},{"id":"https://openalex.org/keywords/microdissection","display_name":"microdissection","score":0.5090000033378601},{"id":"https://openalex.org/keywords/extent-of-resection","display_name":"extent of resection","score":0.6019999980926514},{"id":"https://openalex.org/keywords/postoperative-complications","display_name":"postoperative complications","score":0.6240000128746033},{"id":"https://openalex.org/keywords/cavernous-sinus-invasion","display_name":"cavernous sinus invasion","score":0.5960000157356262},{"id":"https://openalex.org/keywords/surgical-outcomes","display_name":"surgical outcomes","score":0.4230000078678131},{"id":"https://openalex.org/keywords/tumor-reconstruction","display_name":"tumor reconstruction","score":0.40400001406669617},{"id":"https://openalex.org/keywords/iatrogenic-injury","display_name":"iatrogenic injury","score":0.5979999899864197},{"id":"https://openalex.org/keywords/repeat-resection","display_name":"repeat resection","score":0.4359999895095825},{"id":"https://openalex.org/keywords/medical-therapy","display_name":"medical therapy","score":0.4189999997615814},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.7829999923706055},{"id":"https://openalex.org/keywords/pituitary-function-recovery","display_name":"pituitary function recovery","score":0.4180000126361847},{"id":"https://openalex.org/keywords/visual-acuity","display_name":"visual acuity","score":0.3050000071525574}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5319856405258179},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.4426146149635315}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1055/s-0044-1779921","doi":"https://doi.org/10.1055/s-0044-1779921","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0044-1779921","pdf_url":null,"source":{"id":"https://openalex.org/S4210197100","display_name":"Journal of Neurological Surgery Part B Skull Base","issn_l":"2193-6331","issn":["2193-6331","2193-634X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurological Surgery Part B: Skull Base","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.6000000238418579,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7168277169","https://openalex.org/W4407249757","https://openalex.org/W4407250649","https://openalex.org/W4285280107","https://openalex.org/W2573650089","https://openalex.org/W4391990519","https://openalex.org/W4407249429","https://openalex.org/W4285108508","https://openalex.org/W2927314539","https://openalex.org/W2149222958"],"abstract_inverted_index":{"Introduction:":[0],"A":[1,33],"small":[2],"subset":[3],"of":[4,27,45,83,164,238,248,298,369,414,443,485,520],"pituitary":[5,84,102,121,170,493,509],"adenomas":[6,20,85,122,463,510],"invade":[7],"the":[8,23,46,75,304,337,367,483],"suprasellar":[9],"subarachnoid":[10,87,124,159,177,205,259,263,315,349,409,436,465,512],"space":[11],"and":[12,52,66,81,112,150,157,203,279,329,397,423,452,477,507,531],"involve":[13],"critical":[14],"neurovascular":[15,50,139,500],"structures.":[16,501],"Compared":[17,255],"to":[18,58,73,110,141,175,256,268,333,482,495,498],"typical":[19,492],"which":[21],"respect":[22],"arachnoid":[24],"plane,":[25],"resection":[26,104,172,272,416,484],"these":[28],"tumors":[29,129,516],"present":[30],"additional":[31,281],"challenges.":[32],"unique":[34],"operative":[35],"approach":[36,99,134],"including":[37,289],"an":[38,96],"expanded":[39],"bony":[40],"exposure,":[41],"careful":[42],"extracapsular":[43],"dissection":[44],"tumor":[47,148,213,219,226,271],"from":[48,91,108,137],"surrounding":[49,138],"structures,":[51],"meticulous":[53],"multi-layered":[54],"reconstruction":[55],"is":[56],"required":[57],"achieve":[59],"maximal":[60,143],"safe":[61,144],"resection,":[62,522],"avoid":[63,496],"iatrogenic":[64],"injury,":[65],"prevent":[67],"post-operative":[68,529],"complications.":[69],"This":[70],"study":[71],"aims":[72],"describe":[74],"presentation,":[76],"nuances":[77],"in":[78,188,212],"surgical":[79,133,470],"management,":[80],"outcomes":[82,151],"with":[86,123,156,202,262,314,348,408,435,464,504,511,517],"invasion.":[88,160,206],"Methods:":[89],"Data":[90],"321":[92],"patients":[93,119,155,165,201,257,313,347,358,407],"who":[94],"underwent":[95,130],"endoscopic":[97],"endonasal":[98],"(EEA)":[100],"for":[101,169,533],"adenoma":[103,171],"was":[105,185,209],"prospectively":[106],"collected":[107],"2018":[109],"2023":[111],"analyzed":[113],"as":[114,179],"a":[115,131,440,468,486,491],"retrospective":[116],"cohort.":[117],"Thirteen":[118],"harboring":[120],"invasion":[125,178,241,264,316,350,360,410,437,513],"were":[126,152,173,265,317,330,379,386],"identified.":[127],"These":[128],"modified":[132],"involving":[135],"microdissection":[136],"structures":[140],"accomplish":[142],"resection.":[145,295],"Patient":[146],"demographics,":[147],"characteristics,":[149],"compared":[153],"across":[154,200,381],"without":[158,204,258,359],"Results:":[161],"Approximately":[162],"4%":[163],"(13/321)":[166],"undergoing":[167],"EEA":[168],"found":[174],"have":[176,269,334],"determined":[180],"by":[181],"intra-operative":[182,353,523],"observation.":[183],"There":[184],"no":[186,210],"difference":[187,211],"age":[189],"(":[190,196,215,222,228,233,242,251],"p":[191,197,216,223,229,234,243,252,276,286,310,326,343,364,376,394,403,420,431,449,458],"=":[192,198,224,230,235,244,253,311,377,395,404,459],"0.67)":[193,199],"or":[194,246,293,488],"gender":[195],"Moreover,":[207],"there":[208],"pathology":[214],">":[217],"0.05),":[218],"functional":[220],"status":[221],"0.16),":[225],"size":[227],"0.43),":[231],"apoplexy":[232],"0.88),":[236,312],"presence":[237],"cavernous":[239,338],"sinus":[240,339],"0.62),":[245],"history":[247],"prior":[249],"surgery":[250,300],"0.24).":[254],"invasion,":[260],"those":[261],"more":[266,318,331,480],"likely":[267,332],"subtotal":[270,521],"(53%":[273,307],"vs.":[274,308,324,341,362,374,392,401,418,429,447,456],"11%,":[275],"<":[277,287,327,344,365,421,432,450],"0.00001)":[278],"require":[280],"treatment":[282],"(33%":[283],"versus":[284],"13%,":[285],"0.01)":[288],"medical":[290,389],"therapy,":[291],"radiation,":[292],"repeat":[294,415],"While":[296],"rates":[297,356,368,413,519],"transcavernous":[299],"remained":[301],"similar":[302,380],"between":[303],"two":[305],"groups":[306],"51%,":[309],"predominantly":[319],"Knosp":[320],"grade":[321],"4":[322],"(27%":[323,340,446],"4%,":[325,448],"0.0001)":[328],"residual":[335],"within":[336],"5%,":[342,393],"0.001).":[345],"Although":[346],"experienced":[351,411],"greater":[352],"CSF":[354,371,524],"leak":[355,372],"than":[357,490],"(100%":[361],"35%,":[363],"0.00001),":[366],"postoperative":[370,384,453,526],"(0%":[373],"3%,":[375],"0.51)":[378],"groups.":[382],"Additional":[383],"interventions":[385],"comparable":[387,481],"regarding":[388],"therapy":[390,427],"(13%":[391,417,428],"0.14)":[396],"stereotactic":[398],"radiosurgery":[399],"(7%":[400,455],"2%,":[402],"0.21),":[405],"although":[406],"higher":[412,441],"1%,":[419],"0.001)":[422,451],"proton":[424],"beam":[425],"radiation":[426],"0%,":[430],"0.0001).":[433],"Patients":[434],"also":[438],"exhibited":[439],"incidence":[442],"diabetes":[444,527],"insipidus":[445],"hematomas":[454],"0.6%,":[457],"0.02).":[460],"Conclusion:":[461],"Pituitary":[462],"extension":[466],"represent":[467],"distinct":[469],"challenge,":[471],"requiring":[472],"microsurgical":[473],"dissection,":[474],"detachment,":[475],"devascularization,":[476],"debulking":[478],"techniques":[479],"meningioma":[487],"craniopharyngioma":[489],"adenoma,":[494],"injury":[497],"adjacent":[499],"Yet,":[502],"even":[503],"this":[505],"recognition":[506],"approach,":[508],"remain":[514],"challenging":[515],"increased":[518],"leak,":[525],"insipidus,":[528],"hematomas,":[530],"need":[532],"adjuvant":[534],"interventions.":[535],"Fig.":[536,538],"1":[537],"2":[539],"Publication":[540],"History":[541],"Article":[542],"published":[543],"online:":[544],"05":[545],"February":[546],"2024":[547],"\u00a9":[548],"2024.":[549],"Thieme.":[550],"All":[551],"rights":[552],"reserved.":[553],"Georg":[554],"Thieme":[555],"Verlag":[556],"KG":[557],"R\u00fcdigerstra\u00dfe":[558],"14,":[559],"70469":[560],"Stuttgart,":[561],"Germany":[562]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2024-02-22T00:00:00"}