{"id":"https://openalex.org/W4391970470","doi":"https://doi.org/10.1002/acn3.52021","title":"Impact of neuromyelitis optica spectrum disorder on employment and income in the United States","display_name":"Impact of neuromyelitis optica spectrum disorder on employment and income in the United States","publication_year":2024,"publication_date":"2024-02-20","ids":{"openalex":"https://openalex.org/W4391970470","doi":"https://doi.org/10.1002/acn3.52021","pmid":"https://pubmed.ncbi.nlm.nih.gov/38374778","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11021617"},"language":"en","primary_location":{"id":"doi:10.1002/acn3.52021","doi":"https://doi.org/10.1002/acn3.52021","is_oa":true,"landing_page_url":"https://doi.org/10.1002/acn3.52021","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.52021","source":{"id":"https://openalex.org/S2764382054","display_name":"Annals of Clinical and Translational Neurology","issn_l":"2328-9503","issn":["2328-9503"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Clinical and Translational Neurology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.52021","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5093588182","display_name":"Isabella Gomez Hjerthen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Isabella Gomez Hjerthen","raw_affiliation_strings":["Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA","School of Engineering and Applied Sciences, Harvard College, Cambridge, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"School of Engineering and Applied Sciences, Harvard College, Cambridge, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093092556","display_name":"Cristina Trapaga Hacker","orcid":"https://orcid.org/0000-0003-1101-0362","observed_orcids":["https://orcid.org/0000-0003-1101-0362"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cristina Tr\u00e1paga Hacker","raw_affiliation_strings":["Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061111709","display_name":"William R. Meador","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William Meador","raw_affiliation_strings":["Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA","Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004669262","display_name":"Ahmed Zayed Obeidat","orcid":"https://orcid.org/0000-0002-3549-3277","observed_orcids":["https://orcid.org/0000-0002-3549-3277"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ahmed Z. Obeidat","raw_affiliation_strings":["Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA"],"raw_orcid":"https://orcid.org/0000-0002-3549-3277","affiliations":[{"raw_affiliation_string":"Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA","institution_ids":["https://openalex.org/I204308271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030843441","display_name":"Lucas Felipe Bastos Horta","orcid":"https://orcid.org/0000-0002-5839-6955","observed_orcids":["https://orcid.org/0000-0002-5839-6955","https://orcid.org/0000-0002-5824-5815"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lucas Horta","raw_affiliation_strings":["Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062928592","display_name":"Farrah Jasmine Mateen","orcid":"https://orcid.org/0000-0002-4293-8115","observed_orcids":["https://orcid.org/0000-0002-4293-8115"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Farrah J. Mateen","raw_affiliation_strings":["Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA","Harvard Medical School, Boston, Massachusetts, USA"],"raw_orcid":"https://orcid.org/0000-0002-4293-8115","affiliations":[{"raw_affiliation_string":"Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5062928592"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"],"apc_list":{"value":3990,"currency":"USD","value_usd":3990},"apc_paid":{"value":3990,"currency":"USD","value_usd":3990},"fwci":2.4153,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.88224438,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"11","issue":"4","first_page":"1011","last_page":"1020"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11514","display_name":"Disability Education and Employment","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/3311","display_name":"Safety Research"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11631","display_name":"Retirement, Disability, and Employment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3317","display_name":"Demography"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuromyelitis-optica-spectrum-disorder","display_name":"neuromyelitis optica spectrum disorder","score":1.0},{"id":"https://openalex.org/keywords/employment","display_name":"employment","score":0.824999988079071},{"id":"https://openalex.org/keywords/income","display_name":"income","score":0.8999999761581421},{"id":"https://openalex.org/keywords/working-hours","display_name":"working hours","score":0.8240000009536743},{"id":"https://openalex.org/keywords/job-loss","display_name":"job loss","score":0.9300000071525574},{"id":"https://openalex.org/keywords/aquaporin-4-antibodies","display_name":"aquaporin-4 antibodies","score":0.6639999747276306},{"id":"https://openalex.org/keywords/mog-antibodies","display_name":"anti-MOG antibodies","score":0.9890000224113464},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.3479999899864197},{"id":"https://openalex.org/keywords/rituximab","display_name":"rituximab","score":0.8640000224113464},{"id":"https://openalex.org/keywords/caregiver-burden","display_name":"caregiver burden","score":0.5109999775886536},{"id":"https://openalex.org/keywords/informal-caregivers","display_name":"informal caregivers","score":0.5889999866485596},{"id":"https://openalex.org/keywords/economic-burden","display_name":"economic burden","score":0.36899998784065247}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9215500354766846},{"id":"https://openalex.org/C2781137167","wikidata":"https://www.wikidata.org/wiki/Q611458","display_name":"Neuromyelitis optica","level":3,"score":0.7839194536209106},{"id":"https://openalex.org/C2776760755","wikidata":"https://www.wikidata.org/wiki/Q18939","display_name":"Azathioprine","level":3,"score":0.49163514375686646},{"id":"https://openalex.org/C2780252810","wikidata":"https://www.wikidata.org/wiki/Q1455316","display_name":"Immunosuppression","level":2,"score":0.46024152636528015},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.4567190408706665},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.44034165143966675},{"id":"https://openalex.org/C2780653079","wikidata":"https://www.wikidata.org/wiki/Q412323","display_name":"Rituximab","level":3,"score":0.41356968879699707},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3934956192970276},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.373629629611969},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31460654735565186},{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.17488878965377808},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.15575242042541504},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.08767423033714294},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000069283","descriptor_name":"Rituximab","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009173","descriptor_name":"Mycophenolic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009471","descriptor_name":"Neuromyelitis Optica","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016756","descriptor_name":"Immunoglobulins, Intravenous","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1002/acn3.52021","doi":"https://doi.org/10.1002/acn3.52021","is_oa":true,"landing_page_url":"https://doi.org/10.1002/acn3.52021","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.52021","source":{"id":"https://openalex.org/S2764382054","display_name":"Annals of Clinical and Translational Neurology","issn_l":"2328-9503","issn":["2328-9503"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Clinical and Translational Neurology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11021617","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11021617","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11021617/pdf/ACN3-11-1011.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ann Clin Transl Neurol","raw_type":"Text"},{"id":"pmid:38374778","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38374778","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of clinical and translational neurology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:52e2c86ffd5e4720bf379968148c671c","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/52e2c86ffd5e4720bf379968148c671c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Annals of Clinical and Translational Neurology, Vol 11, Iss 4, Pp 1011-1020 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1002/acn3.52021","doi":"https://doi.org/10.1002/acn3.52021","is_oa":true,"landing_page_url":"https://doi.org/10.1002/acn3.52021","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.52021","source":{"id":"https://openalex.org/S2764382054","display_name":"Annals of Clinical and Translational Neurology","issn_l":"2328-9503","issn":["2328-9503"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Clinical and Translational Neurology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/8","display_name":"Decent work and economic growth"},{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"},{"score":0.4074000120162964,"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320319146","display_name":"Horizon Therapeutics","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4391970470.pdf","grobid_xml":"https://content.openalex.org/works/W4391970470.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W1977920771","https://openalex.org/W2278851035","https://openalex.org/W2285134363","https://openalex.org/W2599076725","https://openalex.org/W2908202794","https://openalex.org/W2949643330","https://openalex.org/W4223530293","https://openalex.org/W4229025055","https://openalex.org/W4294116629","https://openalex.org/W4295235548","https://openalex.org/W4306888935","https://openalex.org/W4323668124","https://openalex.org/W4390883509"],"related_works":["https://openalex.org/W4405350069","https://openalex.org/W4412112386","https://openalex.org/W2773051144","https://openalex.org/W4411176587","https://openalex.org/W4323668124","https://openalex.org/W4295235548","https://openalex.org/W7203654583","https://openalex.org/W4400882747","https://openalex.org/W4403333051","https://openalex.org/W4403206425"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1],"OBJECTIVES:":[2],"We":[3,244],"aim":[4],"to":[5,39,128,135,239],"characterize":[6],"the":[7,30,148,202,211,215,250,261,269],"sociodemographic":[8],"and":[9,18,54,96,166,258,273],"clinical":[10],"factors":[11],"associated":[12],"with":[13,23,79,102],"loss":[14],"of":[15,84,90,98,140,173,184,206,210,218,223,231,249,252,271],"jobs,":[16],"income,":[17,53],"work":[19,51,56,179,235,256],"hours":[20,236],"in":[21,29,260],"people":[22],"neuromyelitis":[24],"optica":[25],"spectrum":[26],"disorder":[27],"(NMOSD)":[28],"United":[31,262],"States.":[32],"METHODS:":[33],"A":[34],"REDCap-based":[35],"survey":[36],"was":[37],"administered":[38],"working-age":[40],"NMOSD":[41,253],"patients":[42,272],"(18-70":[43],"years":[44,205],"old)":[45],"querying":[46],"demographic":[47],"information,":[48],"symptoms,":[49],"immunosuppression,":[50],"hours,":[52,180,257],"caregiver":[55],"(11/2022-07/2023).":[57],"Regression":[58],"models":[59],"were":[60,100],"developed":[61],"using":[62],"MATLAB.":[63],"RESULTS:":[64],"Of":[65],"127":[66],"participants":[67,141,224],"(97":[68],"female;":[69],"55%":[70],"AQP4-antibody,":[71],"19%":[72],"MOG":[73],"antibody;":[74],"69%":[75],"Caucasian,":[76],"7%":[77,110],"Hispanic),":[78],"an":[80,182],"average":[81,87,183,203],"diagnosis":[82,154],"age":[83],"38.7":[85],"years,":[86,92],"disease":[88,207],"duration":[89,208],"6.4":[91,204],"mean":[93],"3.1":[94],"attacks,":[95],"94%":[97],"whom":[99],"treated":[101],"immune":[103],"system-directed":[104],"therapy":[105],"(53%":[106],"rituximab,":[107],"8%":[108],"satralizumab,":[109],"eculizumab,":[111],"6%":[112],"mycophenolate":[113],"mofetil,":[114],"4%":[115],"inebilizumab,":[116],"2%":[117],"azathioprine,":[118],"10%":[119,121],"IVIg,":[120],"other),":[122],"56%":[123],"lost":[124],"a":[125,168,226,246],"job":[126,169,238],"due":[127],"NMOSD.":[129,242],"Employment":[130],"decreased":[131],"12%":[132],"(80%":[133],"pre-":[134],"68%":[136],"post-diagnosis).":[137],"Thirty-six":[138],"percent":[139,172,222],"said":[142],"they":[143],"no":[144,163],"longer":[145],"worked":[146],"outside":[147],"home.":[149],"Significant":[150],"predictors":[151],"for":[152],"post-NMOSD":[153],"employment":[155],"status":[156],"included":[157],"younger":[158],"age,":[159],"lower":[160],"pain":[161],"level,":[162],"walking":[164],"aids,":[165],"having":[167],"prediagnosis.":[170],"Sixty-eight":[171],"those":[174],"employed":[175],"prediagnosis":[176],"reduced":[177],"their":[178,234,274],"dropping":[181],"18.4":[185],"h":[186],"per":[187],"month":[188],"since":[189],"being":[190],"diagnosed":[191],"(\u00b110.1":[192],"h).":[193],"Average":[194],"annual":[195],"income":[196,259],"grew":[197],"slowly":[198],"at":[199],"$1998":[200],"during":[201],"(14%":[209],"value":[212],"predicted":[213],"by":[214],"U.S.":[216],"Bureau":[217],"Labor":[219],"Statistics).":[220],"Sixty":[221],"had":[225],"regular":[227],"unpaid":[228],"caregiver;":[229],"34%":[230],"caregivers":[232],"changed":[233],"or":[237],"help":[240],"manage":[241],"DISCUSSION:":[243],"provide":[245],"structured":[247],"analysis":[248],"impact":[251],"on":[254,268],"employment,":[255],"States,":[263],"demonstrating":[264],"its":[265],"major":[266],"effect":[267],"livelihoods":[270],"caregivers.":[275]},"counts_by_year":[{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-02-21T00:00:00"}