{"id":"https://openalex.org/W4391968585","doi":"https://doi.org/10.30574/wjarr.2024.21.2.0527","title":"Gravity-driven crossflow membrane filtration and mechanical centrifugation yield plasma with equivalent total and COVID-19-specific immunoglobulin content","display_name":"Gravity-driven crossflow membrane filtration and mechanical centrifugation yield plasma with equivalent total and COVID-19-specific immunoglobulin content","publication_year":2024,"publication_date":"2024-02-20","ids":{"openalex":"https://openalex.org/W4391968585","doi":"https://doi.org/10.30574/wjarr.2024.21.2.0527"},"language":"en","primary_location":{"id":"doi:10.30574/wjarr.2024.21.2.0527","doi":"https://doi.org/10.30574/wjarr.2024.21.2.0527","is_oa":true,"landing_page_url":"https://doi.org/10.30574/wjarr.2024.21.2.0527","pdf_url":"https://wjarr.com/sites/default/files/WJARR-2024-0527.pdf","source":{"id":"https://openalex.org/S4210223820","display_name":"World Journal of Advanced Research and Reviews","issn_l":"2581-9615","issn":["2581-9615"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4383735917","host_organization_name":"GSC Online Press","host_organization_lineage":["https://openalex.org/P4383735917"],"host_organization_lineage_names":["GSC Online Press"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Advanced Research and Reviews","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://wjarr.com/sites/default/files/WJARR-2024-0527.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042181770","display_name":"Rosita Bihariesingh-Sanchit","orcid":"https://orcid.org/0000-0003-0646-9507","observed_orcids":["https://orcid.org/0000-0003-0646-9507"]},"institutions":[{"id":"https://openalex.org/I2799540604","display_name":"Academic Hospital Paramaribo","ror":"https://ror.org/01ky0w731","country_code":"SR","type":"healthcare","lineage":["https://openalex.org/I2799540604"]}],"countries":["SR"],"is_corresponding":true,"raw_author_name":"Rosita Bihariesingh-Sanchit","raw_affiliation_strings":["Department of Anesthesiology, Academic Hospital Paramaribo, Paramaribo, Suriname","Department of Intensive Care, Academic Hospital Paramaribo, Paramaribo, Suriname"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Academic Hospital Paramaribo, Paramaribo, Suriname","institution_ids":["https://openalex.org/I2799540604"]},{"raw_affiliation_string":"Department of Intensive Care, Academic Hospital Paramaribo, Paramaribo, Suriname","institution_ids":["https://openalex.org/I2799540604"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038441238","display_name":"Rakesh Bansie","orcid":"https://orcid.org/0000-0002-5885-3677","observed_orcids":["https://orcid.org/0000-0002-5885-3677"]},"institutions":[{"id":"https://openalex.org/I2799540604","display_name":"Academic Hospital Paramaribo","ror":"https://ror.org/01ky0w731","country_code":"SR","type":"healthcare","lineage":["https://openalex.org/I2799540604"]}],"countries":["SR"],"is_corresponding":false,"raw_author_name":"Rakesh Bansie","raw_affiliation_strings":["Department of Internal Medicine, Academic Hospital Paramaribo, Paramaribo, Suriname"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Academic Hospital Paramaribo, Paramaribo, Suriname","institution_ids":["https://openalex.org/I2799540604"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104246338","display_name":"Shannon Tjon A Sam","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shannon Tjon A Sam","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093963555","display_name":"Cheneal Lieveld","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799540604","display_name":"Academic Hospital Paramaribo","ror":"https://ror.org/01ky0w731","country_code":"SR","type":"healthcare","lineage":["https://openalex.org/I2799540604"]}],"countries":["SR"],"is_corresponding":false,"raw_author_name":"Cheneal Lieveld","raw_affiliation_strings":["Department of Intensive Care, Academic Hospital Paramaribo, Paramaribo, Suriname"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Intensive Care, Academic Hospital Paramaribo, Paramaribo, Suriname","institution_ids":["https://openalex.org/I2799540604"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113123064","display_name":"Anoushka Simons","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799540604","display_name":"Academic Hospital Paramaribo","ror":"https://ror.org/01ky0w731","country_code":"SR","type":"healthcare","lineage":["https://openalex.org/I2799540604"]}],"countries":["SR"],"is_corresponding":false,"raw_author_name":"Anoushka Simons","raw_affiliation_strings":["Department of Intensive Care, Academic Hospital Paramaribo, Paramaribo, Suriname"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Intensive Care, Academic Hospital Paramaribo, Paramaribo, Suriname","institution_ids":["https://openalex.org/I2799540604"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058855168","display_name":"J.N.R. Kromosoeto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799540604","display_name":"Academic Hospital Paramaribo","ror":"https://ror.org/01ky0w731","country_code":"SR","type":"healthcare","lineage":["https://openalex.org/I2799540604"]}],"countries":["SR"],"is_corresponding":false,"raw_author_name":"Jimmy Kromosoeto","raw_affiliation_strings":["Department of Anesthesiology, St. Vincentius Hospital, Paramaribo, Suriname"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, St. Vincentius Hospital, Paramaribo, Suriname","institution_ids":["https://openalex.org/I2799540604"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062777194","display_name":"Sjef J. C. M. van de Leur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146510","display_name":"Isala","ror":"https://ror.org/046a2wj10","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210146510"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Sjef J.C.M. van de Leur","raw_affiliation_strings":["Department of Clinical Chemistry , Isala Clinics , Zwolle , The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Chemistry , Isala Clinics , Zwolle , The Netherlands","institution_ids":["https://openalex.org/I4210146510"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114128702","display_name":"Stephen C. Vreden","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799540604","display_name":"Academic Hospital Paramaribo","ror":"https://ror.org/01ky0w731","country_code":"SR","type":"healthcare","lineage":["https://openalex.org/I2799540604"]}],"countries":["SR"],"is_corresponding":false,"raw_author_name":"Stephen C. Vreden","raw_affiliation_strings":["Department of Internal Medicine , Academic Hospital Paramaribo , Paramaribo , Suriname"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine , Academic Hospital Paramaribo , Paramaribo , Suriname","institution_ids":["https://openalex.org/I2799540604"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031216196","display_name":"Z. Choudhry","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zaheeb Choudhry","raw_affiliation_strings":["Department of Nephrology and Therapeutic Apheresis, Horacio Oduber Hospital, Aruba"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology and Therapeutic Apheresis, Horacio Oduber Hospital, Aruba","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068451297","display_name":"Ang\u00e9lique B. van \u2019t Wout","orcid":"https://orcid.org/0000-0003-3705-2392","observed_orcids":["https://orcid.org/0000-0003-3705-2392"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ang\u00e9lique B. van \u2018t Wout","raw_affiliation_strings":["AlphaBiomics Limited , London , United Kingdom","Van 't Wout Pharma Consulting , Amsterdam , The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AlphaBiomics Limited , London , United Kingdom","institution_ids":[]},{"raw_affiliation_string":"Van 't Wout Pharma Consulting , Amsterdam , The Netherlands","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068063896","display_name":"Marien Isa\u00e4k de Jonge","orcid":"https://orcid.org/0000-0003-2812-5895","observed_orcids":["https://orcid.org/0000-0003-2812-5895"]},"institutions":[{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Marien I. de Jonge","raw_affiliation_strings":["Department of Laboratory Medicine , Laboratory of Medical Immunology , Radboud University Medical Center , Nijmegen , The Netherlands","Radboud Center for Infectious Diseases (RCI) , Radboud University Medical Center , Nijmegen , The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine , Laboratory of Medical Immunology , Radboud University Medical Center , Nijmegen , The Netherlands","institution_ids":["https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Radboud Center for Infectious Diseases (RCI) , Radboud University Medical Center , Nijmegen , The Netherlands","institution_ids":["https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077094573","display_name":"Dimitri Adriaan Diavatopoulos","orcid":"https://orcid.org/0000-0001-7065-7807","observed_orcids":["https://orcid.org/0000-0001-7065-7807"]},"institutions":[{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Dimitri A. Diavatopoulos","raw_affiliation_strings":["Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands","Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I2802934949"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001887359","display_name":"Arno Pieter Nierich","orcid":"https://orcid.org/0000-0003-1221-7277","observed_orcids":["https://orcid.org/0000-0003-1221-7277"]},"institutions":[{"id":"https://openalex.org/I2799540604","display_name":"Academic Hospital Paramaribo","ror":"https://ror.org/01ky0w731","country_code":"SR","type":"healthcare","lineage":["https://openalex.org/I2799540604"]},{"id":"https://openalex.org/I4405267155","display_name":"HemoClear BV (Netherlands)","ror":"https://ror.org/01e8thn03","country_code":"NL","type":"company","lineage":["https://openalex.org/I4405267155"]}],"countries":["NL","SR"],"is_corresponding":false,"raw_author_name":"Arno P. Nierich","raw_affiliation_strings":["Department of Anesthesiology , Academic Hospital Paramaribo , Paramaribo , Suriname","HemoClear BV , Zwolle , The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology , Academic Hospital Paramaribo , Paramaribo , Suriname","institution_ids":["https://openalex.org/I2799540604"]},{"raw_affiliation_string":"HemoClear BV , Zwolle , The Netherlands","institution_ids":["https://openalex.org/I4405267155"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5042181770"],"corresponding_institution_ids":["https://openalex.org/I2799540604"],"apc_list":null,"apc_paid":null,"fwci":0.5839,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.60464031,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"21","issue":"2","first_page":"1107","last_page":"1115"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.5175999999046326,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.5175999999046326,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.149399995803833,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12735","display_name":"Blood donation and transfusion practices","score":0.11349999904632568,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/convalescent-plasma","display_name":"convalescent plasma","score":0.8450000286102295},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.9240000247955322},{"id":"https://openalex.org/keywords/plasmapheresis","display_name":"plasmapheresis","score":0.9129999876022339},{"id":"https://openalex.org/keywords/immunoglobulins","display_name":"immunoglobulins","score":0.7950000166893005},{"id":"https://openalex.org/keywords/igg","display_name":"IgG","score":0.6520000100135803},{"id":"https://openalex.org/keywords/low-and-middle-income-countries","display_name":"low- and middle-income countries","score":0.9070000052452087},{"id":"https://openalex.org/keywords/plasma-collection","display_name":"plasma collection","score":0.5040000081062317}],"concepts":[{"id":"https://openalex.org/C7623868","wikidata":"https://www.wikidata.org/wiki/Q1967135","display_name":"Centrifugation","level":2,"score":0.7439964413642883},{"id":"https://openalex.org/C128489963","wikidata":"https://www.wikidata.org/wiki/Q1187724","display_name":"Filtration (mathematics)","level":2,"score":0.6452873349189758},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5642016530036926},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.537570595741272},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.5291978120803833},{"id":"https://openalex.org/C134121241","wikidata":"https://www.wikidata.org/wiki/Q899301","display_name":"Yield (engineering)","level":2,"score":0.5220962762832642},{"id":"https://openalex.org/C53163501","wikidata":"https://www.wikidata.org/wiki/Q1141078","display_name":"Cross-flow filtration","level":3,"score":0.4856232702732086},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.453967422246933},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4430920481681824},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.4132794141769409},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3176000714302063},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1617494523525238},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.15523594617843628},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1467423141002655},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.1335800290107727},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08388015627861023},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.07721415162086487},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.30574/wjarr.2024.21.2.0527","doi":"https://doi.org/10.30574/wjarr.2024.21.2.0527","is_oa":true,"landing_page_url":"https://doi.org/10.30574/wjarr.2024.21.2.0527","pdf_url":"https://wjarr.com/sites/default/files/WJARR-2024-0527.pdf","source":{"id":"https://openalex.org/S4210223820","display_name":"World Journal of Advanced Research and Reviews","issn_l":"2581-9615","issn":["2581-9615"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4383735917","host_organization_name":"GSC Online Press","host_organization_lineage":["https://openalex.org/P4383735917"],"host_organization_lineage_names":["GSC Online Press"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Advanced Research and Reviews","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.30574/wjarr.2024.21.2.0527","doi":"https://doi.org/10.30574/wjarr.2024.21.2.0527","is_oa":true,"landing_page_url":"https://doi.org/10.30574/wjarr.2024.21.2.0527","pdf_url":"https://wjarr.com/sites/default/files/WJARR-2024-0527.pdf","source":{"id":"https://openalex.org/S4210223820","display_name":"World Journal of Advanced Research and Reviews","issn_l":"2581-9615","issn":["2581-9615"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4383735917","host_organization_name":"GSC Online Press","host_organization_lineage":["https://openalex.org/P4383735917"],"host_organization_lineage_names":["GSC Online Press"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Advanced Research and Reviews","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4391968585.pdf","grobid_xml":"https://content.openalex.org/works/W4391968585.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W1943749260","https://openalex.org/W1995664671","https://openalex.org/W2150391880","https://openalex.org/W2784146546","https://openalex.org/W3013742505","https://openalex.org/W3014735311","https://openalex.org/W3080642689","https://openalex.org/W3087661988","https://openalex.org/W3213925583","https://openalex.org/W4220678499","https://openalex.org/W4250409746","https://openalex.org/W4313544510","https://openalex.org/W4321478322","https://openalex.org/W4321611115","https://openalex.org/W4376129094","https://openalex.org/W4386506065"],"related_works":["https://openalex.org/W3046232576","https://openalex.org/W4206598230","https://openalex.org/W3185955237","https://openalex.org/W7120808146","https://openalex.org/W7118818350","https://openalex.org/W3031223533","https://openalex.org/W4321436111","https://openalex.org/W3014853902","https://openalex.org/W3123425658","https://openalex.org/W4401482025"],"abstract_inverted_index":{"While":[0],"the":[1,25,62,66,83,92,99,150,161,191,228,236,243],"administration":[2],"of":[3,20,29,73,98,128,149,196,221],"convalescent":[4,31,140],"plasma":[5,32,45,89,141,162],"is":[6],"a":[7,56,232],"promising":[8],"therapy":[9,53],"for":[10,91,122,147,194,235],"coronavirus":[11],"disease":[12],"2019":[13],"(COVID-19),":[14],"upfront":[15],"costs":[16],"and":[17,27,36,94,120,145,204,213,223,238],"technological":[18],"barriers":[19],"conventional":[21,78,88,214],"plasmapheresis":[22],"have":[23],"limited":[24],"collection":[26,237],"processing":[28],"COVID-19":[30,110],"(CCP)":[33],"in":[34,59,135,160,242],"Low-":[35],"Middle-Income":[37],"Countries":[38],"(LMICs).":[39],"We":[40],"previously":[41],"reported":[42],"that":[43,210],"bedside":[44],"separation":[46],"using":[47,113],"gravity-driven":[48,67,84,211,229],"microfiltration":[49,68,85,144,212,230],"has":[50],"made":[51],"CCP":[52,217,241],"accessible":[54],"as":[55,75],"treatment":[57,239],"option":[58,234],"Suriname.":[60],"However,":[61],"question":[63],"remains":[64],"whether":[65],"method":[69,86,231],"yields":[70],"similar":[71],"amounts":[72,220],"immunoglobulins":[74],"compared":[76,82],"to":[77,124,170,179],"plasmapheresis.":[79],"Here,":[80],"we":[81],"with":[87,218,240],"centrifugation":[90,146,174,215],"total":[93,197,199,201,222],"COVID-19-specific":[95,136,224],"immunoglobulin":[96],"content":[97],"obtained":[100,142,163],"CCP.":[101],"Blood":[102],"donations":[103],"from":[104,108],"10":[105],"donors":[106],"recovered":[107],"PCR-confirmed":[109],"were":[111,117,132,157,188],"processed":[112],"both":[114,129],"methods.":[115,130],"Samples":[116],"collected":[118],"pre-":[119],"post-processing":[121],"analysis":[123],"allow":[125],"direct":[126],"comparison":[127],"There":[131],"no":[133],"differences":[134,187],"IgG":[137,155,205],"levels":[138,156,195],"between":[139,190],"by":[143],"4":[148],"5":[151],"assays":[152],"used.":[153],"Anti-RBD-Omicron":[154],"slightly":[158],"higher":[159],"after":[164,173],"filtration":[165],"(median":[166,175],"274,":[167],"range":[168,177],"69":[169],"1258)":[171],"than":[172],"249,":[176],"67":[178],"1175),":[180],"Wilcoxon":[181],"P":[182],"=":[183],"0.0488.":[184],"No":[185],"significant":[186],"detected":[189],"two":[192],"methods":[193],"albumin,":[198],"cholesterol,":[200],"IgA,":[202],"IgM":[203],"levels.":[206],"These":[207],"results":[208],"indicate":[209],"yield":[216],"equivalent":[219],"antibodies.":[225],"This":[226],"makes":[227],"viable":[233],"LMICs":[244],"setting.":[245]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2024-02-21T00:00:00"}