{"id":"https://openalex.org/W4391844064","doi":"https://doi.org/10.3390/pathogens13020177","title":"Zika Virus\u2014A Reemerging Neurotropic Arbovirus Associated with Adverse Pregnancy Outcomes and Neuropathogenesis","display_name":"Zika Virus\u2014A Reemerging Neurotropic Arbovirus Associated with Adverse Pregnancy Outcomes and Neuropathogenesis","publication_year":2024,"publication_date":"2024-02-15","ids":{"openalex":"https://openalex.org/W4391844064","doi":"https://doi.org/10.3390/pathogens13020177","pmid":"https://pubmed.ncbi.nlm.nih.gov/38392915","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10892292"},"language":"en","primary_location":{"id":"doi:10.3390/pathogens13020177","doi":"https://doi.org/10.3390/pathogens13020177","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pathogens13020177","pdf_url":"https://www.mdpi.com/2076-0817/13/2/177/pdf?version=1708001100","source":{"id":"https://openalex.org/S4210239906","display_name":"Pathogens","issn_l":"2076-0817","issn":["2076-0817"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathogens","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2076-0817/13/2/177/pdf?version=1708001100","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031837203","display_name":"Kenneth C. Elliott","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1280259254","display_name":"Henry M. Jackson Foundation","ror":"https://ror.org/04q9tew83","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1280259254"]},{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth C. Elliott","raw_affiliation_strings":["Department of Microbiology & Immunology, The Henry M Jackson Foundation for Military Medicine, Uniformed Services University, Bethesda, MD 20814, USA","Department of Microbiology & Immunology, Uniformed Services University, Bethesda, MD 20814, USA","Uniformed Services University, Bethesda, MD 20814, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology & Immunology, The Henry M Jackson Foundation for Military Medicine, Uniformed Services University, Bethesda, MD 20814, USA","institution_ids":["https://openalex.org/I1280259254"]},{"raw_affiliation_string":"Department of Microbiology & Immunology, Uniformed Services University, Bethesda, MD 20814, USA","institution_ids":["https://openalex.org/I148314036"]},{"raw_affiliation_string":"Uniformed Services University, Bethesda, MD 20814, USA","institution_ids":["https://openalex.org/I148314036"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078755301","display_name":"Joseph J. Mattapallil","orcid":"https://orcid.org/0000-0002-7412-9507","observed_orcids":["https://orcid.org/0000-0002-7412-9507"]},"institutions":[{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joseph J. Mattapallil","raw_affiliation_strings":["Department of Microbiology & Immunology, Uniformed Services University, Bethesda, MD 20814, USA"],"raw_orcid":"https://orcid.org/0000-0002-7412-9507","affiliations":[{"raw_affiliation_string":"Department of Microbiology & Immunology, Uniformed Services University, Bethesda, MD 20814, USA","institution_ids":["https://openalex.org/I148314036"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5078755301"],"corresponding_institution_ids":["https://openalex.org/I148314036"],"apc_list":{"value":2700,"currency":"CHF","value_usd":3069},"apc_paid":{"value":2700,"currency":"CHF","value_usd":3069},"fwci":1.405,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.78717949,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"13","issue":"2","first_page":"177","last_page":"177"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12047","display_name":"Viral Infections and Vectors","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/zika-virus","display_name":"Zika virus","score":1.0},{"id":"https://openalex.org/keywords/flavivirus","display_name":"flavivirus","score":0.902999997138977},{"id":"https://openalex.org/keywords/neurotropism","display_name":"neurotropism","score":0.7279999852180481},{"id":"https://openalex.org/keywords/congenital-zika-syndrome","display_name":"congenital Zika syndrome","score":0.8100000023841858},{"id":"https://openalex.org/keywords/guillain-barre-syndrome","display_name":"Guillain-Barr\u00e9 syndrome","score":0.9010000228881836},{"id":"https://openalex.org/keywords/encephalitis","display_name":"encephalitis","score":0.7129999995231628},{"id":"https://openalex.org/keywords/meningitis","display_name":"meningitis","score":0.6840000152587891},{"id":"https://openalex.org/keywords/sexual-transmission","display_name":"sexual transmission","score":0.8019999861717224},{"id":"https://openalex.org/keywords/perinatal-transmission","display_name":"perinatal transmission","score":0.9670000076293945},{"id":"https://openalex.org/keywords/immunological-cross-reactivity","display_name":"immunological cross-reactivity","score":0.5740000009536743},{"id":"https://openalex.org/keywords/dengue-virus","display_name":"dengue virus","score":0.7689999938011169},{"id":"https://openalex.org/keywords/neutralizing-antibodies","display_name":"neutralizing antibodies","score":0.6909999847412109},{"id":"https://openalex.org/keywords/cd8-t-cell-responses","display_name":"CD8+ T cell responses","score":0.8790000081062317},{"id":"https://openalex.org/keywords/vaccine-immunogen-design","display_name":"vaccine immunogen design","score":0.6880000233650208},{"id":"https://openalex.org/keywords/virus-structure","display_name":"virus structure","score":0.5040000081062317},{"id":"https://openalex.org/keywords/immune-evasion","display_name":"immune evasion","score":0.5339999794960022}],"concepts":[{"id":"https://openalex.org/C2777053367","wikidata":"https://www.wikidata.org/wiki/Q202864","display_name":"Zika virus","level":3,"score":0.9135226011276245},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.7748053073883057},{"id":"https://openalex.org/C2778116200","wikidata":"https://www.wikidata.org/wiki/Q630622","display_name":"Arbovirus","level":3,"score":0.5935423374176025},{"id":"https://openalex.org/C2779635636","wikidata":"https://www.wikidata.org/wiki/Q476209","display_name":"Dengue virus","level":3,"score":0.5877048969268799},{"id":"https://openalex.org/C533803919","wikidata":"https://www.wikidata.org/wiki/Q30953","display_name":"Dengue fever","level":2,"score":0.5475611686706543},{"id":"https://openalex.org/C2780568436","wikidata":"https://www.wikidata.org/wiki/Q1165479","display_name":"Flavivirus","level":3,"score":0.47123584151268005},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4618145227432251},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.44512954354286194},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.3785400986671448},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3182738423347473}],"mesh":[{"descriptor_ui":"D000071243","descriptor_name":"Zika Virus Infection","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000071243","descriptor_name":"Zika Virus Infection","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D000071243","descriptor_name":"Zika Virus Infection","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D000071244","descriptor_name":"Zika Virus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000914","descriptor_name":"Antibodies, Viral","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003429","descriptor_name":"Cross Reactions","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003716","descriptor_name":"Dengue Virus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011251","descriptor_name":"Pregnancy Complications, Infectious","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011251","descriptor_name":"Pregnancy Complications, Infectious","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011251","descriptor_name":"Pregnancy Complications, Infectious","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D011256","descriptor_name":"Pregnancy Outcome","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D018414","descriptor_name":"CD8-Positive T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D020275","descriptor_name":"Guillain-Barre Syndrome","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D020275","descriptor_name":"Guillain-Barre Syndrome","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D020275","descriptor_name":"Guillain-Barre Syndrome","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D020275","descriptor_name":"Guillain-Barre Syndrome","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D057134","descriptor_name":"Antibodies, Neutralizing","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D057134","descriptor_name":"Antibodies, Neutralizing","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3390/pathogens13020177","doi":"https://doi.org/10.3390/pathogens13020177","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pathogens13020177","pdf_url":"https://www.mdpi.com/2076-0817/13/2/177/pdf?version=1708001100","source":{"id":"https://openalex.org/S4210239906","display_name":"Pathogens","issn_l":"2076-0817","issn":["2076-0817"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathogens","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10892292","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10892292","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10892292/pdf/pathogens-13-00177.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathogens","raw_type":"Text"},{"id":"pmid:38392915","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38392915","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathogens (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:a04ad24895914219926077505bce8f98","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/a04ad24895914219926077505bce8f98","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pathogens, Vol 13, Iss 2, p 177 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/pathogens13020177","doi":"https://doi.org/10.3390/pathogens13020177","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pathogens13020177","pdf_url":"https://www.mdpi.com/2076-0817/13/2/177/pdf?version=1708001100","source":{"id":"https://openalex.org/S4210239906","display_name":"Pathogens","issn_l":"2076-0817","issn":["2076-0817"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathogens","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4391844064.pdf","grobid_xml":"https://content.openalex.org/works/W4391844064.grobid-xml"},"referenced_works_count":191,"referenced_works":["https://openalex.org/W1968071906","https://openalex.org/W1973619678","https://openalex.org/W1975120587","https://openalex.org/W1976308168","https://openalex.org/W1985294654","https://openalex.org/W1993651229","https://openalex.org/W2006214221","https://openalex.org/W2012551953","https://openalex.org/W2042530028","https://openalex.org/W2047365750","https://openalex.org/W2065276673","https://openalex.org/W2068751098","https://openalex.org/W2073049582","https://openalex.org/W2081342613","https://openalex.org/W2087151076","https://openalex.org/W2090127796","https://openalex.org/W2119292034","https://openalex.org/W2124547357","https://openalex.org/W2125566625","https://openalex.org/W2138527314","https://openalex.org/W2142445664","https://openalex.org/W2167041942","https://openalex.org/W2178559328","https://openalex.org/W2178932929","https://openalex.org/W2224061626","https://openalex.org/W2277664010","https://openalex.org/W2277850893","https://openalex.org/W2288486409","https://openalex.org/W2289704315","https://openalex.org/W2292034915","https://openalex.org/W2293707105","https://openalex.org/W2294983505","https://openalex.org/W2295245778","https://openalex.org/W2321791060","https://openalex.org/W2327959547","https://openalex.org/W2333018296","https://openalex.org/W2335029448","https://openalex.org/W2335127767","https://openalex.org/W2338703441","https://openalex.org/W2345638947","https://openalex.org/W2346122645","https://openalex.org/W2346372208","https://openalex.org/W2346484133","https://openalex.org/W2400855681","https://openalex.org/W2405496925","https://openalex.org/W2412153247","https://openalex.org/W2460692594","https://openalex.org/W2461605911","https://openalex.org/W2464735068","https://openalex.org/W2469258508","https://openalex.org/W2489760462","https://openalex.org/W2493146871","https://openalex.org/W2510187969","https://openalex.org/W2515326166","https://openalex.org/W2518406360","https://openalex.org/W2518728671","https://openalex.org/W2519998274","https://openalex.org/W2528733278","https://openalex.org/W2529443144","https://openalex.org/W2538612363","https://openalex.org/W2539130992","https://openalex.org/W2546845633","https://openalex.org/W2546889486","https://openalex.org/W2551940318","https://openalex.org/W2564382896","https://openalex.org/W2567109063","https://openalex.org/W2570993046","https://openalex.org/W2571430932","https://openalex.org/W2577798709","https://openalex.org/W2584249987","https://openalex.org/W2587277868","https://openalex.org/W2587850379","https://openalex.org/W2588207387","https://openalex.org/W2589226646","https://openalex.org/W2594135889","https://openalex.org/W2604098753","https://openalex.org/W2605946416","https://openalex.org/W2610442760","https://openalex.org/W2614980328","https://openalex.org/W2617274523","https://openalex.org/W2618918047","https://openalex.org/W2620298867","https://openalex.org/W2624571024","https://openalex.org/W2673196552","https://openalex.org/W2745794351","https://openalex.org/W2749582671","https://openalex.org/W2752337702","https://openalex.org/W2753787192","https://openalex.org/W2755187147","https://openalex.org/W2760003140","https://openalex.org/W2760337654","https://openalex.org/W2760364797","https://openalex.org/W2761680340","https://openalex.org/W2768431258","https://openalex.org/W2768924487","https://openalex.org/W2776497640","https://openalex.org/W2781555529","https://openalex.org/W2783170893","https://openalex.org/W2784201211","https://openalex.org/W2786313719","https://openalex.org/W2792422559","https://openalex.org/W2794257526","https://openalex.org/W2797119872","https://openalex.org/W2797350331","https://openalex.org/W2801013503","https://openalex.org/W2804586592","https://openalex.org/W2808947321","https://openalex.org/W2838060337","https://openalex.org/W2849330166","https://openalex.org/W2884928200","https://openalex.org/W2885094735","https://openalex.org/W2889817565","https://openalex.org/W2892068086","https://openalex.org/W2899044014","https://openalex.org/W2901065350","https://openalex.org/W2902753196","https://openalex.org/W2903985069","https://openalex.org/W2907768116","https://openalex.org/W2914654039","https://openalex.org/W2914723032","https://openalex.org/W2920868010","https://openalex.org/W2921782305","https://openalex.org/W2941347504","https://openalex.org/W2946749496","https://openalex.org/W2947905105","https://openalex.org/W2948133227","https://openalex.org/W2949208852","https://openalex.org/W2949245609","https://openalex.org/W2950833983","https://openalex.org/W2953229326","https://openalex.org/W2955786652","https://openalex.org/W2959171710","https://openalex.org/W2971685987","https://openalex.org/W2973041413","https://openalex.org/W2979411325","https://openalex.org/W2982308767","https://openalex.org/W2982703661","https://openalex.org/W2997878790","https://openalex.org/W2997947400","https://openalex.org/W3004159088","https://openalex.org/W3005697799","https://openalex.org/W3008526556","https://openalex.org/W3035630903","https://openalex.org/W3045544130","https://openalex.org/W3046522781","https://openalex.org/W3047138066","https://openalex.org/W3047192664","https://openalex.org/W3047642829","https://openalex.org/W3080379602","https://openalex.org/W3080470203","https://openalex.org/W3083604060","https://openalex.org/W3087244807","https://openalex.org/W3087906323","https://openalex.org/W3092429904","https://openalex.org/W3095436082","https://openalex.org/W3096439859","https://openalex.org/W3107417040","https://openalex.org/W3126234398","https://openalex.org/W3132116325","https://openalex.org/W3134863639","https://openalex.org/W3137413543","https://openalex.org/W3164874824","https://openalex.org/W3178069284","https://openalex.org/W3191434637","https://openalex.org/W3195785009","https://openalex.org/W3206657111","https://openalex.org/W3212891259","https://openalex.org/W4200068373","https://openalex.org/W4200171952","https://openalex.org/W4210525002","https://openalex.org/W4213432032","https://openalex.org/W4231020630","https://openalex.org/W4297496628","https://openalex.org/W4310251723","https://openalex.org/W4310370480","https://openalex.org/W4313374845","https://openalex.org/W4313375380","https://openalex.org/W4315782168","https://openalex.org/W4366597842","https://openalex.org/W4377014735","https://openalex.org/W4379618959","https://openalex.org/W4380685719","https://openalex.org/W4385694287","https://openalex.org/W4386305835","https://openalex.org/W4387965499","https://openalex.org/W4388421886","https://openalex.org/W4389136745","https://openalex.org/W4399118652","https://openalex.org/W6713548928","https://openalex.org/W6743879993","https://openalex.org/W6806186800"],"related_works":["https://openalex.org/W2613423833","https://openalex.org/W2621647460","https://openalex.org/W2669509643","https://openalex.org/W2788787368","https://openalex.org/W2774769719","https://openalex.org/W3207177444","https://openalex.org/W4299564803","https://openalex.org/W2736493714","https://openalex.org/W2582850730","https://openalex.org/W2982405267"],"abstract_inverted_index":{"Zika":[0,72],"virus":[1,123],"(ZIKV)":[2],"is":[3,8,95,211],"a":[4,142,148],"reemerging":[5],"flavivirus":[6],"that":[7,61,133,174,210],"primarily":[9,36],"spread":[10],"through":[11],"bites":[12],"from":[13],"infected":[14],"mosquitos.":[15],"It":[16],"was":[17,50],"first":[18],"discovered":[19],"in":[20,22,25,37,48,75,86],"1947":[21],"sentinel":[23],"monkeys":[24],"Uganda":[26],"and":[27,39,65,77,84,98,108,121,155,164,202],"has":[28],"since":[29],"been":[30],"the":[31,45,53,70,101,116,127,145,187,194,203,207],"cause":[32],"of":[33,55,58,103,129,147,157,160,190,196,206],"several":[34],"outbreaks,":[35,44],"tropical":[38],"subtropical":[40],"areas.":[41],"Unlike":[42],"earlier":[43],"2015\u20132016":[46],"epidemic":[47],"Brazil":[49],"characterized":[51,99],"by":[52,92,100,213],"emergence":[54],"neurovirulent":[56],"strains":[57,60],"ZIKV":[59,93,120,151,163,191,200,214],"could":[62,134],"be":[63,178],"sexually":[64],"perinatally":[66],"transmitted,":[67],"leading":[68],"to":[69,126,180],"Congenital":[71],"Syndrome":[73,79],"(CZS)":[74],"newborns,":[76],"Guillain-Barre":[78],"(GBS)":[80],"along":[81,166,192],"with":[82,167,193,199],"encephalitis":[83],"meningitis":[85],"adults.":[87],"The":[88,153],"immune":[89,131,208],"response":[90,209],"elicited":[91,212],"infection":[94,201],"highly":[96,149],"effective":[97],"induction":[102,128],"both":[104,162],"ZIKV-specific":[105],"neutralizing":[106],"antibodies":[107,158],"robust":[109],"effector":[110],"CD8+":[111,169],"T":[112,170],"cell":[113,171],"responses.":[114],"However,":[115],"structural":[117,188],"similarities":[118],"between":[119],"Dengue":[122],"(DENV)":[124],"lead":[125],"cross-reactive":[130,168],"responses":[132,172],"potentially":[135],"enhance":[136],"subsequent":[137],"DENV":[138,165],"infection,":[139],"which":[140],"imposes":[141],"constraint":[143],"on":[144],"development":[146],"efficacious":[150],"vaccine.":[152],"isolation":[154],"characterization":[156],"capable":[159],"cross-neutralizing":[161],"suggest":[173],"vaccine":[175],"immunogens":[176],"can":[177],"designed":[179],"overcome":[181],"these":[182],"constraints.":[183],"Here":[184],"we":[185],"review":[186],"characteristics":[189],"evidence":[195],"neuropathogenesis":[197],"associated":[198],"complex":[204],"nature":[205],"infection.":[215]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-02-16T00:00:00"}