{"id":"https://openalex.org/W4391753699","doi":"https://doi.org/10.3390/bios14020095","title":"Development of Taste Sensor with Lipid/Polymer Membranes for Detection of Umami Substances Using Surface Modification","display_name":"Development of Taste Sensor with Lipid/Polymer Membranes for Detection of Umami Substances Using Surface Modification","publication_year":2024,"publication_date":"2024-02-11","ids":{"openalex":"https://openalex.org/W4391753699","doi":"https://doi.org/10.3390/bios14020095","pmid":"https://pubmed.ncbi.nlm.nih.gov/38392014","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10887241"},"language":"en","primary_location":{"id":"doi:10.3390/bios14020095","doi":"https://doi.org/10.3390/bios14020095","is_oa":true,"landing_page_url":"https://doi.org/10.3390/bios14020095","pdf_url":"https://www.mdpi.com/2079-6374/14/2/95/pdf?version=1707640508","source":{"id":"https://openalex.org/S150925516","display_name":"Biosensors","issn_l":"2079-6374","issn":["2079-6374"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2079-6374/14/2/95/pdf?version=1707640508","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062014173","display_name":"Wenhao Yuan","orcid":"https://orcid.org/0009-0007-4958-9441","observed_orcids":["https://orcid.org/0009-0007-4958-9441"]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Wenhao Yuan","raw_affiliation_strings":["Graduate School of Information Science and Electrical Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan"],"raw_orcid":"https://orcid.org/0009-0007-4958-9441","affiliations":[{"raw_affiliation_string":"Graduate School of Information Science and Electrical Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan","institution_ids":["https://openalex.org/I135598925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101585446","display_name":"Zeyu Zhao","orcid":"https://orcid.org/0000-0002-4300-1738","observed_orcids":["https://orcid.org/0000-0002-4300-1738"]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Zeyu Zhao","raw_affiliation_strings":["Graduate School of Information Science and Electrical Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Information Science and Electrical Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan","institution_ids":["https://openalex.org/I135598925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019110921","display_name":"Shunsuke Kimura","orcid":"https://orcid.org/0000-0001-7314-5540","observed_orcids":["https://orcid.org/0000-0001-7314-5540"]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]},{"id":"https://openalex.org/I4405287385","display_name":"Research and Development Center for Five-Sense Devices, Kyushu University","ror":"https://ror.org/0514rer66","country_code":"JP","type":"facility","lineage":["https://openalex.org/I135598925","https://openalex.org/I4405287385"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shunsuke Kimura","raw_affiliation_strings":["Research and Development Center for Five-Sense Devices, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan"],"raw_orcid":"https://orcid.org/0000-0001-7314-5540","affiliations":[{"raw_affiliation_string":"Research and Development Center for Five-Sense Devices, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan","institution_ids":["https://openalex.org/I135598925","https://openalex.org/I4405287385"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112040232","display_name":"Kiyoshi Toko","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]},{"id":"https://openalex.org/I4405286845","display_name":"Kyushu University Institute for Advanced Study","ror":"https://ror.org/039pja661","country_code":"JP","type":"facility","lineage":["https://openalex.org/I135598925","https://openalex.org/I4405286845"]},{"id":"https://openalex.org/I4405287385","display_name":"Research and Development Center for Five-Sense Devices, Kyushu University","ror":"https://ror.org/0514rer66","country_code":"JP","type":"facility","lineage":["https://openalex.org/I135598925","https://openalex.org/I4405287385"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kiyoshi Toko","raw_affiliation_strings":["Institute for Advanced Study, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan","Research and Development Center for Five-Sense Devices, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Advanced Study, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan","institution_ids":["https://openalex.org/I135598925","https://openalex.org/I4405286845"]},{"raw_affiliation_string":"Research and Development Center for Five-Sense Devices, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan","institution_ids":["https://openalex.org/I135598925","https://openalex.org/I4405287385"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5112040232"],"corresponding_institution_ids":["https://openalex.org/I135598925","https://openalex.org/I4405286845","https://openalex.org/I4405287385"],"apc_list":{"value":2700,"currency":"CHF","value_usd":3069},"apc_paid":{"value":2700,"currency":"CHF","value_usd":3069},"fwci":1.3928,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.76363571,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"14","issue":"2","first_page":"95","last_page":"95"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11584","display_name":"Biochemical Analysis and Sensing Techniques","score":0.7592999935150146,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11584","display_name":"Biochemical Analysis and Sensing Techniques","score":0.7592999935150146,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.12849999964237213,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.06340000033378601,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/taste-sensor","display_name":"taste sensor","score":0.9570000171661377},{"id":"https://openalex.org/keywords/lipid-polymer-membranes","display_name":"lipid/polymer membranes","score":0.9290000200271606},{"id":"https://openalex.org/keywords/monosodium-glutamate","display_name":"monosodium glutamate","score":0.8709999918937683},{"id":"https://openalex.org/keywords/surface-modification","display_name":"surface modification","score":0.8059999942779541},{"id":"https://openalex.org/keywords/carboxyl-groups","display_name":"carboxyl groups","score":0.7960000038146973},{"id":"https://openalex.org/keywords/intramolecular-hydrogen-bonding","display_name":"intramolecular hydrogen bonding","score":0.9089999794960022},{"id":"https://openalex.org/keywords/membrane-potential","display_name":"membrane potential","score":0.5690000057220459}],"concepts":[{"id":"https://openalex.org/C2776946002","wikidata":"https://www.wikidata.org/wiki/Q202637","display_name":"Umami","level":3,"score":0.9895058870315552},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8043244481086731},{"id":"https://openalex.org/C8868529","wikidata":"https://www.wikidata.org/wiki/Q124794","display_name":"Taste","level":2,"score":0.7757540941238403},{"id":"https://openalex.org/C2776989845","wikidata":"https://www.wikidata.org/wiki/Q179678","display_name":"Monosodium glutamate","level":2,"score":0.711121678352356},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.578879714012146},{"id":"https://openalex.org/C2776622989","wikidata":"https://www.wikidata.org/wiki/Q184782","display_name":"Phosphoric acid","level":2,"score":0.45083391666412354},{"id":"https://openalex.org/C118792377","wikidata":"https://www.wikidata.org/wiki/Q108584245","display_name":"Selectivity","level":3,"score":0.44135695695877075},{"id":"https://openalex.org/C38858142","wikidata":"https://www.wikidata.org/wiki/Q3821292","display_name":"Aftertaste","level":3,"score":0.43016254901885986},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.42925602197647095},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3084416389465332},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2956897020339966},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.25421303510665894},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012970","descriptor_name":"Sodium Glutamate","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013649","descriptor_name":"Taste","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.3390/bios14020095","doi":"https://doi.org/10.3390/bios14020095","is_oa":true,"landing_page_url":"https://doi.org/10.3390/bios14020095","pdf_url":"https://www.mdpi.com/2079-6374/14/2/95/pdf?version=1707640508","source":{"id":"https://openalex.org/S150925516","display_name":"Biosensors","issn_l":"2079-6374","issn":["2079-6374"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10887241","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10887241","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10887241/pdf/biosensors-14-00095.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors (Basel)","raw_type":"Text"},{"id":"pmid:38392014","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38392014","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:4a0cd4c93c314d67ae31c1d208141c54","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/4a0cd4c93c314d67ae31c1d208141c54","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biosensors, Vol 14, Iss 2, p 95 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/bios14020095","doi":"https://doi.org/10.3390/bios14020095","is_oa":true,"landing_page_url":"https://doi.org/10.3390/bios14020095","pdf_url":"https://www.mdpi.com/2079-6374/14/2/95/pdf?version=1707640508","source":{"id":"https://openalex.org/S150925516","display_name":"Biosensors","issn_l":"2079-6374","issn":["2079-6374"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G6239866820","display_name":"Development of Novel Taste Sensor Using Allostery","funder_award_id":"21H05006","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4391753699.pdf","grobid_xml":"https://content.openalex.org/works/W4391753699.grobid-xml"},"referenced_works_count":68,"referenced_works":["https://openalex.org/W1235558738","https://openalex.org/W1779641998","https://openalex.org/W1865553564","https://openalex.org/W1869285760","https://openalex.org/W1967754883","https://openalex.org/W1967870346","https://openalex.org/W1968670574","https://openalex.org/W1974109301","https://openalex.org/W1977357428","https://openalex.org/W1981609139","https://openalex.org/W1983845337","https://openalex.org/W1985696604","https://openalex.org/W1986364353","https://openalex.org/W1996157147","https://openalex.org/W1998823894","https://openalex.org/W2013560772","https://openalex.org/W2027503646","https://openalex.org/W2034350807","https://openalex.org/W2039139441","https://openalex.org/W2040474773","https://openalex.org/W2046912419","https://openalex.org/W2049209791","https://openalex.org/W2049342431","https://openalex.org/W2049682677","https://openalex.org/W2049854801","https://openalex.org/W2057102050","https://openalex.org/W2062560346","https://openalex.org/W2063082079","https://openalex.org/W2065878163","https://openalex.org/W2068317838","https://openalex.org/W2068322437","https://openalex.org/W2085872178","https://openalex.org/W2087253274","https://openalex.org/W2092557227","https://openalex.org/W2151202430","https://openalex.org/W2387744194","https://openalex.org/W2403920160","https://openalex.org/W2493384574","https://openalex.org/W2728186791","https://openalex.org/W2739293431","https://openalex.org/W2749086208","https://openalex.org/W2776735955","https://openalex.org/W2781659948","https://openalex.org/W2790559546","https://openalex.org/W2792475275","https://openalex.org/W2972493059","https://openalex.org/W2990606142","https://openalex.org/W2991478808","https://openalex.org/W2998239166","https://openalex.org/W3004161764","https://openalex.org/W3009596829","https://openalex.org/W3012723384","https://openalex.org/W3034538066","https://openalex.org/W3036728843","https://openalex.org/W3090703459","https://openalex.org/W3164864185","https://openalex.org/W3196789224","https://openalex.org/W4212766257","https://openalex.org/W4221105236","https://openalex.org/W4233153321","https://openalex.org/W4239904705","https://openalex.org/W4251422341","https://openalex.org/W4297143957","https://openalex.org/W4310906889","https://openalex.org/W4318586510","https://openalex.org/W4321768881","https://openalex.org/W4381110646","https://openalex.org/W6740741057"],"related_works":["https://openalex.org/W4408286246","https://openalex.org/W2128349169","https://openalex.org/W4415489819","https://openalex.org/W7135101286","https://openalex.org/W4255752163","https://openalex.org/W4401215913","https://openalex.org/W2070745505","https://openalex.org/W2046019769","https://openalex.org/W4404723998","https://openalex.org/W6886238606"],"abstract_inverted_index":{"A":[0],"taste":[1,12,30,64,73,92,166],"sensor":[2,74,167],"employs":[3],"various":[4],"lipid/polymer":[5],"membranes":[6],"with":[7,169],"specific":[8],"physicochemical":[9],"properties":[10],"for":[11,28,35,75,94,120,177],"classification":[13],"and":[14,53,150],"evaluation.":[15],"However,":[16],"phosphoric":[17],"acid":[18],"di(2-ethylhexyl)":[19],"ester":[20],"(PAEE),":[21],"employed":[22],"as":[23,105,141,143],"one":[24],"of":[25,40,46,62,101,132,137,157,172],"the":[26,29,44,50,54,110,116,130,138,147,155,161],"lipids":[27,47],"sensors,":[31],"exhibits":[32],"insufficient":[33],"selectivity":[34,176],"umami":[36,63,77,122,162,178],"substances.":[37,179],"The":[38,126,165],"pH":[39],"sample":[41],"solutions":[42],"impacts":[43],"dissociation":[45],"to":[48,56,69,91],"influence":[49],"membrane":[51],"potential,":[52],"response":[55],"astringent":[57],"substances":[58,78,123],"makes":[59],"accurate":[60],"measurement":[61],"difficult.":[65],"This":[66],"study":[67],"aims":[68],"develop":[70],"a":[71,87,158],"novel":[72],"detecting":[76],"like":[79],"monosodium":[80],"L-glutamate":[81],"(MSG)":[82],"through":[83],"surface":[84],"modification,":[85],"i.e.,":[86],"methodology":[88],"previously":[89],"applied":[90],"sensors":[93],"non-charged":[95],"bitter":[96],"substance":[97,163],"measurement.":[98,164],"Four":[99],"kinds":[100],"modifiers":[102],"were":[103],"tested":[104],"membrane-modifying":[106],"materials.":[107],"By":[108],"comparing":[109],"results":[111],"obtained":[112],"from":[113],"these":[114],"modifiers,":[115],"modifier":[117,159,173],"structure":[118],"suitable":[119],"measuring":[121],"was":[124],"identified.":[125],"findings":[127],"revealed":[128],"that":[129],"presence":[131],"carboxyl":[133,148],"groups":[134],"at":[135],"para-position":[136],"benzene":[139],"ring,":[140],"well":[142],"intramolecular":[144],"H-bonds":[145],"between":[146],"group":[149],"hydroxyl":[151],"group,":[152],"significantly":[153],"affect":[154],"effectiveness":[156],"in":[160],"treated":[168],"this":[170],"type":[171],"showed":[174],"excellent":[175]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-02-13T00:00:00"}