{"id":"https://openalex.org/W4391716677","doi":"https://doi.org/10.1038/s41467-024-45684-3","title":"TFIP11 promotes replication fork reversal to preserve genome stability","display_name":"TFIP11 promotes replication fork reversal to preserve genome stability","publication_year":2024,"publication_date":"2024-02-10","ids":{"openalex":"https://openalex.org/W4391716677","doi":"https://doi.org/10.1038/s41467-024-45684-3","pmid":"https://pubmed.ncbi.nlm.nih.gov/38341452","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10858868"},"language":"en","primary_location":{"id":"doi:10.1038/s41467-024-45684-3","doi":"https://doi.org/10.1038/s41467-024-45684-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-024-45684-3","pdf_url":"https://www.nature.com/articles/s41467-024-45684-3.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41467-024-45684-3.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084914364","display_name":"Junliang Chen","orcid":"https://orcid.org/0000-0001-9452-4697","observed_orcids":["https://orcid.org/0000-0001-9452-4697"]},"institutions":[{"id":"https://openalex.org/I4210119853","display_name":"Zhejiang Hospital","ror":"https://ror.org/02kzr5g33","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210119853"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junliang Chen","raw_affiliation_strings":["Center for Life Sciences, Shaoxing Institute, Zhejiang University, 321000, Shaoxing, China","The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China","Zhejiang Provincial Key Laboratory of Geriatrics and Geriatrics Institute of Zhejiang Province, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Life Sciences, Shaoxing Institute, Zhejiang University, 321000, Shaoxing, China","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"Zhejiang Provincial Key Laboratory of Geriatrics and Geriatrics Institute of Zhejiang Province, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China","institution_ids":["https://openalex.org/I4210119853","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103951972","display_name":"Mingjie Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingjie Wu","raw_affiliation_strings":["The Trauma Center, The First Affiliated Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Trauma Center, The First Affiliated Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107911081","display_name":"Yulan Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yulan Yang","raw_affiliation_strings":["The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017011454","display_name":"Chunyan Ruan","orcid":"https://orcid.org/0000-0001-7170-5831","observed_orcids":["https://orcid.org/0000-0001-7170-5831"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunyan Ruan","raw_affiliation_strings":["The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069358812","display_name":"Yi Luo","orcid":"https://orcid.org/0000-0001-7051-219X","observed_orcids":["https://orcid.org/0000-0001-7051-219X"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Luo","raw_affiliation_strings":["The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075444056","display_name":"Lizhi Song","orcid":"https://orcid.org/0009-0006-2570-7004","observed_orcids":["https://orcid.org/0009-0006-2570-7004"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lizhi Song","raw_affiliation_strings":["The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China"],"raw_orcid":"https://orcid.org/0009-0006-2570-7004","affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087865441","display_name":"Ting Wu","orcid":"https://orcid.org/0000-0002-6994-104X","observed_orcids":["https://orcid.org/0000-0002-6994-104X"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ting Wu","raw_affiliation_strings":["The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052632562","display_name":"Jun Huang","orcid":"https://orcid.org/0000-0002-7837-653X","observed_orcids":["https://orcid.org/0000-0002-7837-653X"]},"institutions":[{"id":"https://openalex.org/I4210119853","display_name":"Zhejiang Hospital","ror":"https://ror.org/02kzr5g33","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210119853"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Huang","raw_affiliation_strings":["The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China","Zhejiang Provincial Key Laboratory of Geriatrics and Geriatrics Institute of Zhejiang Province, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China"],"raw_orcid":"https://orcid.org/0000-0002-7837-653X","affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"Zhejiang Provincial Key Laboratory of Geriatrics and Geriatrics Institute of Zhejiang Province, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China","institution_ids":["https://openalex.org/I4210119853","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059065464","display_name":"Bing Yang","orcid":"https://orcid.org/0000-0001-6739-2932","observed_orcids":["https://orcid.org/0000-0001-6739-2932","https://orcid.org/0009-0004-8590-5358"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bing Yang","raw_affiliation_strings":["The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China"],"raw_orcid":"https://orcid.org/0000-0001-6739-2932","affiliations":[{"raw_affiliation_string":"The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 310058, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101610236","display_name":"Ting Liu","orcid":"https://orcid.org/0000-0002-7956-3396","observed_orcids":["https://orcid.org/0000-0002-7956-3396"]},"institutions":[{"id":"https://openalex.org/I4210119853","display_name":"Zhejiang Hospital","ror":"https://ror.org/02kzr5g33","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210119853"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ting Liu","raw_affiliation_strings":["Department of Cell Biology, Zhejiang University School of Medicine, 310058, Hangzhou, China. liuting518@zju.edu.cn","Zhejiang Provincial Key Laboratory of Geriatrics and Geriatrics Institute of Zhejiang Province, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China. liuting518@zju.edu.cn","Department of Cell Biology, Zhejiang University School of Medicine, 310058, Hangzhou, China"],"raw_orcid":"https://orcid.org/0000-0002-7956-3396","affiliations":[{"raw_affiliation_string":"Department of Cell Biology, Zhejiang University School of Medicine, 310058, Hangzhou, China. liuting518@zju.edu.cn","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"Zhejiang Provincial Key Laboratory of Geriatrics and Geriatrics Institute of Zhejiang Province, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China. liuting518@zju.edu.cn","institution_ids":["https://openalex.org/I4210119853","https://openalex.org/I76130692"]},{"raw_affiliation_string":"Department of Cell Biology, Zhejiang University School of Medicine, 310058, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5101610236"],"corresponding_institution_ids":["https://openalex.org/I4210119853","https://openalex.org/I76130692"],"apc_list":{"value":6790,"currency":"USD","value_usd":6790},"apc_paid":{"value":6790,"currency":"USD","value_usd":6790},"fwci":1.2233,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.76364124,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"15","issue":"1","first_page":"1262","last_page":"1262"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10937","display_name":"Telomeres, Telomerase, and Senescence","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/blm-helicase","display_name":"BLM helicase","score":0.8920000195503235},{"id":"https://openalex.org/keywords/replication-fork-reversal","display_name":"replication fork reversal","score":0.9829999804496765},{"id":"https://openalex.org/keywords/replication-stress","display_name":"replication stress","score":0.843999981880188},{"id":"https://openalex.org/keywords/genomic-stability","display_name":"genome stability","score":0.7559999823570251},{"id":"https://openalex.org/keywords/chromosomal-instability","display_name":"chromosomal instability","score":0.7770000100135803},{"id":"https://openalex.org/keywords/rad51","display_name":"RAD51","score":0.9369999766349792},{"id":"https://openalex.org/keywords/recq-helicase","display_name":"RecQ helicase","score":0.8009999990463257},{"id":"https://openalex.org/keywords/stalled-replication-forks","display_name":"stalled replication forks","score":0.7459999918937683},{"id":"https://openalex.org/keywords/protein-dna-interactions","display_name":"protein-DNA interactions","score":0.656000018119812},{"id":"https://openalex.org/keywords/protein-protein-complex-formation","display_name":"protein-protein complex formation","score":0.5630000233650208}],"concepts":[{"id":"https://openalex.org/C161223559","wikidata":"https://www.wikidata.org/wiki/Q138864","display_name":"Helicase","level":4,"score":0.7809599041938782},{"id":"https://openalex.org/C175248279","wikidata":"https://www.wikidata.org/wiki/Q3858415","display_name":"Minichromosome maintenance","level":5,"score":0.753822922706604},{"id":"https://openalex.org/C2779012473","wikidata":"https://www.wikidata.org/wiki/Q3235015","display_name":"RAD51","level":4,"score":0.6477779746055603},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6246538162231445},{"id":"https://openalex.org/C2779013463","wikidata":"https://www.wikidata.org/wiki/Q1469646","display_name":"Bloom syndrome","level":5,"score":0.588646650314331},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5830004811286926},{"id":"https://openalex.org/C2780751114","wikidata":"https://www.wikidata.org/wiki/Q7302254","display_name":"RecQ helicase","level":5,"score":0.5683205723762512},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5658988356590271},{"id":"https://openalex.org/C73573662","wikidata":"https://www.wikidata.org/wiki/Q130996","display_name":"DNA replication","level":3,"score":0.5576782822608948},{"id":"https://openalex.org/C178169997","wikidata":"https://www.wikidata.org/wiki/Q2892636","display_name":"Genome instability","level":4,"score":0.5463760495185852},{"id":"https://openalex.org/C104690221","wikidata":"https://www.wikidata.org/wiki/Q5165872","display_name":"Control of chromosome duplication","level":4,"score":0.4209821820259094},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.40984299778938293},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.35442960262298584},{"id":"https://openalex.org/C134935766","wikidata":"https://www.wikidata.org/wiki/Q210538","display_name":"DNA repair","level":3,"score":0.24866923689842224},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.2070053517818451},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000072260","descriptor_name":"RNA Splicing Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000097122","descriptor_name":"DNA Damage Tolerance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004261","descriptor_name":"DNA Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042822","descriptor_name":"Genomic Instability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051135","descriptor_name":"Rad51 Recombinase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051135","descriptor_name":"Rad51 Recombinase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D053484","descriptor_name":"RecQ Helicases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053484","descriptor_name":"RecQ Helicases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1038/s41467-024-45684-3","doi":"https://doi.org/10.1038/s41467-024-45684-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-024-45684-3","pdf_url":"https://www.nature.com/articles/s41467-024-45684-3.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10858868","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10858868","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10858868/pdf/41467_2024_Article_45684.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nat Commun","raw_type":"Text"},{"id":"pmid:38341452","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38341452","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature communications","raw_type":"Journal Article"},{"id":"pmh:oai:RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-45684-3","doi":null,"is_oa":false,"landing_page_url":"https://www.nature.com/articles/s41467-024-45684-3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:00f7c422a4dd4430b23246b18637fc0c","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/00f7c422a4dd4430b23246b18637fc0c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41467-024-45684-3","doi":"https://doi.org/10.1038/s41467-024-45684-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-024-45684-3","pdf_url":"https://www.nature.com/articles/s41467-024-45684-3.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4000000059604645,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1016302644","display_name":null,"funder_award_id":"31971220","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1947931836","display_name":"XPF\u86cb\u767d\u7684\u4e59\u9170\u5316\u4fee\u9970\u5728DNA\u635f\u4f24\u4fee\u590d\u4e2d\u7684\u529f\u80fd\u4e0e\u4f5c\u7528\u673a\u5236\u7814\u7a76","funder_award_id":"31970664","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3346196684","display_name":"TIP39 \u8c03\u63a7\u590d\u5236\u53c9\u7a33\u5b9a\u6027\u4e0ePARP \u6291\u5236\u5242\u8010\u836f\u7684\u673a\u5236\u7814\u7a76","funder_award_id":"LZ24C070002","funder_id":"https://openalex.org/F4320338464","funder_display_name":"Natural Science Foundation of Zhejiang Province"},{"id":"https://openalex.org/G3637454188","display_name":"SRAD\u5728DNA\u53cc\u94fe\u65ad\u88c2\u635f\u4f24\u4fee\u590d\u9014\u5f84\u9009\u62e9\u4e2d\u7684\u4f5c\u7528\u53ca\u5176\u673a\u5236","funder_award_id":"31730021","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3760006649","display_name":null,"funder_award_id":"2022YFA1302800","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G4761251382","display_name":null,"funder_award_id":"31961160725","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5336272186","display_name":null,"funder_award_id":"2021YFA1101000","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G7436199236","display_name":null,"funder_award_id":"31822031","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8862820813","display_name":null,"funder_award_id":"32270769","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320326297","display_name":"Fok Ying Tung Education Foundation","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320338464","display_name":"Natural Science Foundation of Zhejiang Province","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4391716677.pdf","grobid_xml":"https://content.openalex.org/works/W4391716677.grobid-xml"},"referenced_works_count":75,"referenced_works":["https://openalex.org/W1808263692","https://openalex.org/W1873662011","https://openalex.org/W1963563101","https://openalex.org/W1966950471","https://openalex.org/W1970069044","https://openalex.org/W1970578083","https://openalex.org/W1970898019","https://openalex.org/W1972932327","https://openalex.org/W1983711411","https://openalex.org/W1987086578","https://openalex.org/W1987146639","https://openalex.org/W1994704295","https://openalex.org/W1998727638","https://openalex.org/W1999120412","https://openalex.org/W1999757141","https://openalex.org/W2004699718","https://openalex.org/W2005855776","https://openalex.org/W2008529786","https://openalex.org/W2010160165","https://openalex.org/W2012312296","https://openalex.org/W2021252097","https://openalex.org/W2030639168","https://openalex.org/W2031567993","https://openalex.org/W2035692319","https://openalex.org/W2038246003","https://openalex.org/W2039674107","https://openalex.org/W2039784108","https://openalex.org/W2042056279","https://openalex.org/W2052289985","https://openalex.org/W2052547134","https://openalex.org/W2056870028","https://openalex.org/W2062101590","https://openalex.org/W2070781513","https://openalex.org/W2077436902","https://openalex.org/W2080716570","https://openalex.org/W2082447947","https://openalex.org/W2083273205","https://openalex.org/W2084772885","https://openalex.org/W2087746152","https://openalex.org/W2104584181","https://openalex.org/W2106892764","https://openalex.org/W2117602431","https://openalex.org/W2117613018","https://openalex.org/W2121027597","https://openalex.org/W2122623363","https://openalex.org/W2124204427","https://openalex.org/W2132222969","https://openalex.org/W2132587601","https://openalex.org/W2132641227","https://openalex.org/W2135785842","https://openalex.org/W2146533600","https://openalex.org/W2149045141","https://openalex.org/W2150909798","https://openalex.org/W2154870331","https://openalex.org/W2162378349","https://openalex.org/W2173561323","https://openalex.org/W2473363865","https://openalex.org/W2542071790","https://openalex.org/W2577344516","https://openalex.org/W2737083047","https://openalex.org/W2737658553","https://openalex.org/W2751450140","https://openalex.org/W2754242788","https://openalex.org/W2759812252","https://openalex.org/W2760968141","https://openalex.org/W2763248055","https://openalex.org/W2765392650","https://openalex.org/W2765875601","https://openalex.org/W2771808827","https://openalex.org/W2914441724","https://openalex.org/W3043743907","https://openalex.org/W3113025221","https://openalex.org/W3172335938","https://openalex.org/W3213010392","https://openalex.org/W4281691846"],"related_works":["https://openalex.org/W2078438237","https://openalex.org/W1966950471","https://openalex.org/W3172335938","https://openalex.org/W2409124218","https://openalex.org/W7164452066","https://openalex.org/W3163775954","https://openalex.org/W1516566300","https://openalex.org/W2165346898","https://openalex.org/W2015078392","https://openalex.org/W7160533057"],"abstract_inverted_index":{"Replication":[0],"fork":[1,112],"reversal,":[2],"a":[3,17,29,64,72,129],"critical":[4],"protective":[5],"mechanism":[6,133],"against":[7],"replication":[8,86,119],"stress":[9],"in":[10,40,108],"higher":[11],"eukaryotic":[12],"cells,":[13],"is":[14,38],"orchestrated":[15],"via":[16],"series":[18],"of":[19,31,89,98,138],"coordinated":[20],"enzymatic":[21],"reactions.":[22],"The":[23],"Bloom":[24],"syndrome":[25],"gene":[26],"product,":[27],"BLM,":[28],"member":[30],"the":[32,58,67,81,96,99,136],"highly":[33],"conserved":[34],"RecQ":[35],"helicase":[36],"family,":[37],"implicated":[39],"this":[41,53],"process,":[42],"yet":[43],"its":[44],"precise":[45],"regulation":[46],"and":[47,114,122,140],"role":[48],"remain":[49],"poorly":[50],"understood.":[51],"In":[52],"study,":[54],"we":[55],"demonstrate":[56],"that":[57,79,134],"GCFC":[59],"domain-containing":[60],"protein":[61,101],"TFIP11":[62,70,91],"forms":[63],"complex":[65],"with":[66],"BLM":[68,93,139],"helicase.":[69],"exhibits":[71],"preference":[73],"for":[74],"binding":[75],"to":[76,95,118],"DNA":[77],"substrates":[78],"mimic":[80],"structure":[82],"generated":[83],"at":[84,102,142],"stalled":[85,103,143],"forks.":[87,104],"Loss":[88],"either":[90],"or":[92],"leads":[94],"accumulation":[97],"other":[100],"This":[105],"abnormal":[106],"accumulation,":[107],"turn,":[109],"impairs":[110],"RAD51-mediated":[111],"reversal":[113],"slowing,":[115],"sensitizes":[116],"cells":[117],"stress-inducing":[120],"agents,":[121],"enhances":[123],"chromosomal":[124],"instability.":[125],"These":[126],"findings":[127],"reveal":[128],"previously":[130],"unidentified":[131],"regulatory":[132],"modulates":[135],"activities":[137],"RAD51":[141],"forks,":[144],"thereby":[145],"impacting":[146],"genome":[147],"integrity.":[148]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2024-02-11T00:00:00"}